SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01284

Identifier
NUCLEARECPTR  [View Relations]  [View Alignment]  
Accession
PR01284
No. of Motifs
11
Creation Date
16-FEB-2000
Title
Orphan nuclear receptor (4A nuclear receptor) family signature
Database References
PRINTS; PR00398 STRDHORMONER; PR01285 HMRNUCRECPTR; PR01287 NURRNUCRCPTR
Literature References
1. NUCLEAR RECEPTORS NOMENCLATURE COMMITTEE
A unified nomenclature system for the nuclear receptor superfamily.
CELL 97 161-163 (1999).
 
2. NISHIKAWA, J-I., KITAURA, M., IMAGAWA, M. AND NISHIHARA, T.
Vitamin D receptor contains multiple dimerisation interfaces that
are functionally different.
NUCLEIC ACIDS RES. 23(4) 606-611 (1995).
 
3. DE VOS, P., SCHMITT, J., VERHOEVEN, G. AND STUNNENBERG, G.
Human androgen receptor expressed in HeLa cells activates transcription
in vitro.
NUCLEIC ACIDS RES. 22(7) 1161-1166 (1994).
 
4. OHKURA, N., HIJIKURO, M., YAMAMOTO, A. AND MIKI, K.
Molecular cloning of a novel thyroid/steroid receptor superfamily gene from
cultured rat neuronal cells.
BIOCHEM.BIOPHYS.RES.COMMUN. 205 1959-1965 (1994).
 
5. LAW, S.W., CONNEELY, O.M., DEMAYO, F.J. AND O'MALLEY, B.W.
Identification of a new brain-specific transcription factor, NURR1.
MOL.ENDOCRINOL. 2129-2135 (1992). 
 
6. WILSON, T.E., PAULSEN, R.E., PADGETT, K.A. AND MILBRANDT, J.
Participation of non-zinc finger residues in DNA binding by two nuclear 
orphan receptors.
SCIENCE 256 107-110 (1992). 
 
7. CLARK, J., BENJAMIN, H., GILL, S., SIDHAR, S., GOODWIN, G., CREW, J.,
GUSTERSON, B.A., SHIPLEY, J. AND COOPER, C.S.
Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor
gene superfamily, in a human myxoid chondrosarcoma.
ONCOGENE 12 229-235 (1996). 

Documentation
Steroid or nuclear hormone receptors (NRs) constitute an important super-
family of transcription regulators that are involved in widely diverse 
physiological functions, including control of embryonic development, cell
differentiation and homeostasis [1]. Members of the superfamily include the
steroid hormone receptors and receptors for thyroid hormone, retinoids, 
1,25-dihydroxy-vitamin D3 and a variety of other ligands. The proteins 
function as dimeric molecules in nuclei to regulate the transcription of 
target genes in a ligand-responsive manner [2,3]. In addition to C-terminal
ligand-binding domains, these nuclear receptors contain a highly-conserved,
N-terminal zinc-finger that mediates specific binding to target DNA 
sequences, termed ligand-responsive elements. In the absence of ligand,
steroid hormone receptors are thought to be weakly associated with nuclear
components; hormone binding greatly increases receptor affinity.
 
NRs are extremely important in medical research, a large number of them
being implicated in diseases such as cancer, diabetes, hormone resistance
syndromes, etc. [1]. While several NRs act as ligand-inducible transcription
factors, many do not yet have a defined ligand and are accordingly termed 
"orphan" receptors. During the last decade, more than 300 NRs have been
described, many of which are orphans, which cannot easily be named due to 
current nomenclature confusions in the literature. However, a new system 
has recently been introduced in an attempt to rationalise the increasingly 
complex set of names used to describe superfamily members [1].
 
Novel members of the steroid receptor superfamily designated NOR-1 (neuron
derived orphan receptor) [4], Nurr1 (Nur-related factor 1) [5], and NGFI-B
[6] have been identified from forebrain neuronal cells undergoing apoptosis,
from brain cortex, and from lung, superior cervical ganglia and adrenal 
tissue respectively. The NOR-1 protein binds to the B1a response-element,
which has been identified as the target sequence of the Nur77 family,
suggesting that three members of the Nur77 family may transactivate common
target gene(s) at different situations [4]. Ewing's sarcoma is characterised
by chromosomal translocations that involve the NOR protein [7].
 
NUCLEARECPTR is an 11-element fingerprint that provides a signature for the
orphan nuclear receptor family. The fingerprint was derived from an initial
alignment of 11 sequences: the motifs were drawn from conserved regions
spanning virtually the full alignment length, focusing on those sections
that characterise members of the nuclear receptor family but distinguish 
them from the rest of the steroid hormone receptor superfamily - motifs 1-3
lie N-terminal to the zinc finger domain; motifs 4 and 5 lie between the
zinc fingers and putative ligand-binding domain; motifs 6 and 7 encode the
N- and C-terminal extremities of the ligand-binding domain; and motifs 8-11
reside at the C-terminus. A single iteration on SPTR37_10f was required to
reach convergence, no further sequences being identified beyond the starting
set. Several partial matches were found, all of which appear to be N- or 
C-terminally truncated homologues.
Summary Information
  11 codes involving 11 elements
0 codes involving 10 elements
1 codes involving 9 elements
1 codes involving 8 elements
0 codes involving 7 elements
0 codes involving 6 elements
3 codes involving 5 elements
0 codes involving 4 elements
1 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
111111111111111111111111
1000000000000
900111111111
800011111111
700000000000
600000000000
533333000000
400000000000
311100000000
200000000000
1234567891011
True Positives
NR41_CANFA    NR41_HUMAN    NR41_MOUSE    NR41_RAT      
NR42_HUMAN NR42_MOUSE NR42_RAT NR42_XENLA
NR43_HUMAN NR43_RAT O97726
True Positive Partials
Codes involving 9 elements
Q16311
Codes involving 8 elements
HR38_DROME
Codes involving 5 elements
NOR2_RAT O97727 Q14979
Codes involving 3 elements
Q15627
Sequence Titles
NR41_CANFA  ORPHAN NUCLEAR RECEPTOR HMR (ORPHAN NUCLEAR RECEPTOR NGFI-B) - CANIS FAMILIARIS  
NR41_HUMAN ORPHAN NUCLEAR RECEPTOR HMR (EARLY RESPONSE PROTEIN NAK1) (TR3 ORPHAN RECEPTOR)
NR41_MOUSE ORPHAN NUCLEAR RECEPTOR HMR (NUCLEAR HORMONE RECEPTOR NUR/77) (N10 NUCLEAR PROTE
NR41_RAT ORPHAN NUCLEAR RECEPTOR HMR (NERVE GROWTH FACTOR INDUCED PROTEIN I-B) (NGFI-B) (
NR42_HUMAN ORPHAN NUCLEAR RECEPTOR NURR1 (IMMEDIATE-EARLY RESPONSE PROTEIN NOT) (TRANSCRIPT
NR42_MOUSE ORPHAN NUCLEAR RECEPTOR NURR1 (NUR-RELATED FACTOR 1) - MUS MUSCULUS (MOUSE).
NR42_RAT ORPHAN NUCLEAR RECEPTOR NURR1 (NUR-RELATED FACTOR 1) (REGENERATING LIVER NUCLEAR
NR42_XENLA ORPHAN NUCLEAR RECEPTOR NURR1 (NERVE GROWTH FACTOR INDUCED PROTEIN I-B HOMOLOG)
NR43_HUMAN NUCLEAR HORMONE RECEPTOR NOR-1 (NEURON-DERIVED ORPHAN RECEPTOR 1) (MITOGEN INDUC
NR43_RAT NUCLEAR HORMONE RECEPTOR NOR-1 (NEURON-DERIVED ORPHAN RECEPTOR 1) - RATTUS NORVE
O97726 NEURON-DERIVED ORPHAN RECEPTOR-1 ALFA - SUS SCROFA (PIG).

Q16311 TINUR= NGFI-B/NUR77 BETA-TYPE TRANSCRIPTION FACTOR HOMOLOG - HOMO SAPIENS (HUMAN

HR38_DROME PROBABLE NUCLEAR HORMONE RECEPTOR HR38 (DHR38) - DROSOPHILA MELANOGASTER (FRUIT

NOR2_RAT NUCLEAR HORMONE RECEPTOR NOR-2 (NEURON-DERIVED ORPHAN RECEPTOR 2) - RATTUS NORVE
O97727 NEURON-DERIVED ORPHAN RECEPTOR-1 BETA - SUS SCROFA (PIG).
Q14979 NUCLEAR RECEPTOR - HOMO SAPIENS (HUMAN).

Q15627 TR3BETA - HOMO SAPIENS (HUMAN).
Scan History
SPTR37_10f 2  50   NSINGLE    
Initial Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
DPLTPEFIKPTMDLASPE NR41_HUMAN 24 24 -
DPLTPELSKPTMDLASPE NR41_CANFA 24 24 -
DFLTPEFVKFSMDLTNTE NR42_RAT 33 33 -
DFLTPEFVKFSMDLTNTE NR42_MOUSE 33 33 -
DFLTPEFVKFSMDLTNTE NR42_HUMAN 33 33 -
DPLALEFSKPTMDLASPE NR41_RAT 24 24 -
DPLALEFGKPTMDLASPE NR41_MOUSE 24 24 -
DILNSEFGKFTMDLVNSE NR42_XENLA 24 24 -
DILNSEFGKFTMDLVNSE NR42_XENLA 24 24 -
EIMNPDYTKLTMDLGSTE NR43_HUMAN 29 29 -
EIMNPDYAKLTMDLGSTG NR43_RAT 29 29 -

Motif 2 width=14
Element Seqn Id St Int Rpt
APTALPSFSTFMDG NR41_HUMAN 46 4 -
APTALPSFSTFMDG NR41_CANFA 46 4 -
ATTSLPSFSTFMDN NR42_RAT 53 2 -
ATTSLPSFSTFMDN NR42_MOUSE 53 2 -
ATTSLPSFSTFMDN NR42_HUMAN 53 2 -
APATLPSFSTFMDG NR41_RAT 46 4 -
APATLPSFSTFMDG NR41_MOUSE 46 4 -
ASTSLPSFSTFMDG NR42_XENLA 44 2 -
ASTSLPSFSTFMDG NR42_XENLA 44 2 -
ATTSLPSISTFVEG NR43_HUMAN 51 4 -
ATTSLPSFSTFMEG NR43_RAT 51 4 -

Motif 3 width=16
Element Seqn Id St Int Rpt
SPSTPSFQPPQLSPWD NR41_HUMAN 140 80 -
SPSTPSFQPPQLSPWD NR41_CANFA 140 80 -
TPSTPGFQVQHSPMWD NR42_RAT 129 62 -
TPSTPSFQVQHSPMWD NR42_MOUSE 129 62 -
TPTTPGFQVQHSPMWD NR42_HUMAN 129 62 -
SPPTPNFQPSQLSPWD NR41_RAT 139 79 -
SPSTPNFQPSQLSPWD NR41_MOUSE 142 82 -
SPSTPGFQNPQLPTWE NR42_XENLA 117 59 -
SPSTPGFQNPQLPTWE NR42_XENLA 117 59 -
TPTTPAFPPQAGALWD NR43_HUMAN 142 77 -
TPTTPGFPPQAGALWD NR43_RAT 144 79 -

Motif 4 width=16
Element Seqn Id St Int Rpt
TDSLKGRRGRLPSKPK NR41_HUMAN 339 183 -
TDSLKGRRGRLPSKPK NR41_CANFA 339 183 -
TDSLKGRRGRLPSKPK NR42_RAT 335 190 -
TDSLKGRRGRLPSKPK NR42_MOUSE 335 190 -
TDSLKGRRGRLPSKPK NR42_HUMAN 335 190 -
TDSLKGRRGRLPSKPK NR41_RAT 338 183 -
TDSLKGRRGRLPSKPK NR41_MOUSE 342 184 -
TDSLKGRRGRLPSKPK NR42_XENLA 318 185 -
TDSLKGRRGRLPSKPK NR42_XENLA 318 185 -
TDSLKGRRGRLPSKPK NR43_HUMAN 364 206 -
TDSLKGRRGRLPSKPK NR43_RAT 366 206 -

Motif 5 width=17
Element Seqn Id St Int Rpt
PANLLTSLVRAHLDSGP NR41_HUMAN 361 6 -
PANLLTSLVRAHLDSGP NR41_CANFA 361 6 -
PVSLISALVRAHVDSNP NR42_RAT 361 10 -
PVSLISALVRAHVDSNP NR42_MOUSE 361 10 -
PVSLISALVRAHVDSNP NR42_HUMAN 361 10 -
PTNLLTSLIRAHLDSGP NR41_RAT 360 6 -
PTNLLTSLIRAHLDSGP NR41_MOUSE 364 6 -
PVDLINSLVRAHIDSIP NR42_XENLA 340 6 -
PVDLINSLVRAHIDSIP NR42_XENLA 340 6 -
PICMMNALVRALTDSTP NR43_HUMAN 395 15 -
PICMMNALVRALTDATP NR43_RAT 397 15 -

Motif 6 width=15
Element Seqn Id St Int Rpt
QQFYDLLSGSLEVIR NR41_HUMAN 404 26 -
QQFYDLLSGSLEVIR NR41_CANFA 404 26 -
QQFYDLLTGSMEIIR NR42_RAT 404 26 -
QQFYDLLTGSMEIIR NR42_MOUSE 404 26 -
QQFYDLLTGSMEIIR NR42_HUMAN 404 26 -
QQFYDLLSGSLDVIR NR41_RAT 403 26 -
QQFYDLLSGSLDVIR NR41_MOUSE 407 26 -
QQFYDLLSGSLEVIR NR42_XENLA 383 26 -
QQFYDLLSGSLEVIR NR42_XENLA 383 26 -
QQFYNLLTASIDVSR NR43_HUMAN 435 23 -
QQFYNLLTASIDVSR NR43_RAT 437 23 -

Motif 7 width=21
Element Seqn Id St Int Rpt
RSKPGEGKLIFCSGLVLHRLQ NR41_HUMAN 454 35 -
RSKPAEGKLIFCSGLVLHRLQ NR41_CANFA 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_RAT 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_MOUSE 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_HUMAN 454 35 -
RSKPGEGKLIFCSGLVLHRLQ NR41_RAT 453 35 -
RSKPGEGKLIFCSGLVLHQLQ NR41_MOUSE 457 35 -
RSRPEEGKLIFCNGVVLHRTQ NR42_XENLA 433 35 -
RSRPEEGKLIFCNGVVLHRTQ NR42_XENLA 433 35 -
RSNTAEDKFVFCNGLVLHRLQ NR43_HUMAN 485 35 -
RSNTAEDKFVFCNGLVLHRLQ NR43_RAT 487 35 -

Motif 8 width=16
Element Seqn Id St Int Rpt
CARGFGDWIDSILAFS NR41_HUMAN 475 0 -
CARGFGDWIDSILAFS NR41_CANFA 475 0 -
CVRGFGEWIDSIVEFS NR42_RAT 475 0 -
CVRGFGEWIDSIVEFS NR42_MOUSE 475 0 -
CVRGFGEWIDSIVEFS NR42_HUMAN 475 0 -
CARGFGDWIDNILAFS NR41_RAT 474 0 -
CARGFGDWIDNILAFS NR41_MOUSE 478 0 -
CVRGFGEWIDSIIEFS NR42_XENLA 454 0 -
CVRGFGEWIDSIIEFS NR42_XENLA 454 0 -
CLRGFGEWLDSIKDFS NR43_HUMAN 506 0 -
CLRGFGEWLDSIKDFS NR43_RAT 508 0 -

Motif 9 width=18
Element Seqn Id St Int Rpt
PRRVEELQNRIASCLKEH NR41_HUMAN 521 30 -
PRRVEELQNRIASCLKEH NR41_CANFA 521 30 -
PKRVEELQNKIVNCLKDH NR42_RAT 521 30 -
PKRVEELQNKIVNCLKDH NR42_MOUSE 521 30 -
PKRVEELQNKIVNCLKDH NR42_HUMAN 521 30 -
PRRVEELQNRIASCLKEH NR41_RAT 520 30 -
PRRVEELQNRIASCLKEH NR41_MOUSE 524 30 -
PKKVEELQSQIINCLKEH NR42_XENLA 500 30 -
PKKVEELQSQIINCLKEH NR42_XENLA 500 30 -
PKRVEELCNKITSSLKDH NR43_HUMAN 552 30 -
PKRVEELCNKITSSLKDH NR43_RAT 554 30 -

Motif 10 width=21
Element Seqn Id St Int Rpt
RLLGKLPELRTLCTQGLQRIF NR41_HUMAN 554 15 -
RLLGKLPELRTLCTQGLQRIF NR41_CANFA 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_RAT 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_MOUSE 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_HUMAN 554 15 -
RLLGKLPELRTLCTQGLQRIF NR41_RAT 553 15 -
RLLGKLPELRTLCTQGLQRIF NR41_MOUSE 557 15 -
KLLGKLPELRTLCTQGLQRIF NR42_XENLA 533 15 -
KLLGKLPELRTLCTQGLQRIF NR42_XENLA 533 15 -
KVLGALVELRKICTLGLQRIF NR43_HUMAN 582 12 -
KVLRALVELRKICTQGLQRIF NR43_RAT 584 12 -

Motif 11 width=22
Element Seqn Id St Int Rpt
YLKLEDLVPPPPIIDKIFMDTL NR41_HUMAN 575 0 -
YLKLEDLVPPPPIVDKIFMDTL NR41_CANFA 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_RAT 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_MOUSE 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_HUMAN 575 0 -
CLKLEDLVPPPPIVDKIFMDTL NR41_RAT 574 0 -
CLKLEDLVPPPPIVDKIFMDTL NR41_MOUSE 578 0 -
YLKLEDLVPPPPIVDKIFMDTL NR42_XENLA 554 0 -
YLKLEDLVPPPPIVDKIFMDTL NR42_XENLA 554 0 -
YLKLEDLVSPPSIIDKLFLDTL NR43_HUMAN 603 0 -
YLKLEDLVSPPSVIDKLFLDTL NR43_RAT 605 0 -
Final Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
DPLTPEFIKPTMDLASPE NR41_HUMAN 24 24 -
DPLTPELSKPTMDLASPE NR41_CANFA 24 24 -
DFLTPEFVKFSMDLTNTE NR42_RAT 33 33 -
DFLTPEFVKFSMDLTNTE NR42_MOUSE 33 33 -
DFLTPEFVKFSMDLTNTE NR42_HUMAN 33 33 -
DPLALEFSKPTMDLASPE NR41_RAT 24 24 -
DPLALEFGKPTMDLASPE NR41_MOUSE 24 24 -
DILNSEFGKFTMDLVNSE NR42_XENLA 24 24 -
DILNSEFGKFTMDLVNSE NR42_XENLA 24 24 -
EIMNPDYTKLTMDLGSTE O97726 29 29 -
EIMNPDYTKLTMDLGSTE NR43_HUMAN 29 29 -
EIMNPDYAKLTMDLGSTG NR43_RAT 29 29 -

Motif 2 width=14
Element Seqn Id St Int Rpt
APTALPSFSTFMDG NR41_HUMAN 46 4 -
APTALPSFSTFMDG NR41_CANFA 46 4 -
ATTSLPSFSTFMDN NR42_RAT 53 2 -
ATTSLPSFSTFMDN NR42_MOUSE 53 2 -
ATTSLPSFSTFMDN NR42_HUMAN 53 2 -
APATLPSFSTFMDG NR41_RAT 46 4 -
APATLPSFSTFMDG NR41_MOUSE 46 4 -
ASTSLPSFSTFMDG NR42_XENLA 44 2 -
ASTSLPSFSTFMDG NR42_XENLA 44 2 -
ATTSLPSFSTFMEG O97726 51 4 -
ATTSLPSISTFVEG NR43_HUMAN 51 4 -
ATTSLPSFSTFMEG NR43_RAT 51 4 -

Motif 3 width=16
Element Seqn Id St Int Rpt
SPSTPSFQPPQLSPWD NR41_HUMAN 140 80 -
SPSTPSFQPPQLSPWD NR41_CANFA 140 80 -
TPSTPGFQVQHSPMWD NR42_RAT 129 62 -
TPSTPSFQVQHSPMWD NR42_MOUSE 129 62 -
TPTTPGFQVQHSPMWD NR42_HUMAN 129 62 -
SPPTPNFQPSQLSPWD NR41_RAT 139 79 -
SPSTPNFQPSQLSPWD NR41_MOUSE 142 82 -
SPSTPGFQNPQLPTWE NR42_XENLA 117 59 -
SPSTPGFQNPQLPTWE NR42_XENLA 117 59 -
TPTTPVFPQQAGALWE O97726 154 89 -
TPTTPAFPPQAGALWD NR43_HUMAN 142 77 -
TPTTPGFPPQAGALWD NR43_RAT 144 79 -

Motif 4 width=16
Element Seqn Id St Int Rpt
TDSLKGRRGRLPSKPK NR41_HUMAN 339 183 -
TDSLKGRRGRLPSKPK NR41_CANFA 339 183 -
TDSLKGRRGRLPSKPK NR42_RAT 335 190 -
TDSLKGRRGRLPSKPK NR42_MOUSE 335 190 -
TDSLKGRRGRLPSKPK NR42_HUMAN 335 190 -
TDSLKGRRGRLPSKPK NR41_RAT 338 183 -
TDSLKGRRGRLPSKPK NR41_MOUSE 342 184 -
TDSLKGRRGRLPSKPK NR42_XENLA 318 185 -
TDSLKGRRGRLPSKPK NR42_XENLA 318 185 -
TDSLKGRRGRLPSKPK O97726 381 211 -
TDSLKGRRGRLPSKPK NR43_HUMAN 364 206 -
TDSLKGRRGRLPSKPK NR43_RAT 366 206 -

Motif 5 width=17
Element Seqn Id St Int Rpt
PANLLTSLVRAHLDSGP NR41_HUMAN 361 6 -
PANLLTSLVRAHLDSGP NR41_CANFA 361 6 -
PVSLISALVRAHVDSNP NR42_RAT 361 10 -
PVSLISALVRAHVDSNP NR42_MOUSE 361 10 -
PVSLISALVRAHVDSNP NR42_HUMAN 361 10 -
PTNLLTSLIRAHLDSGP NR41_RAT 360 6 -
PTNLLTSLIRAHLDSGP NR41_MOUSE 364 6 -
PVDLINSLVRAHIDSIP NR42_XENLA 340 6 -
PVDLINSLVRAHIDSIP NR42_XENLA 340 6 -
PVCMMNALVRALTDSTP O97726 412 15 -
PICMMNALVRALTDSTP NR43_HUMAN 395 15 -
PICMMNALVRALTDATP NR43_RAT 397 15 -

Motif 6 width=15
Element Seqn Id St Int Rpt
QQFYDLLSGSLEVIR NR41_HUMAN 404 26 -
QQFYDLLSGSLEVIR NR41_CANFA 404 26 -
QQFYDLLTGSMEIIR NR42_RAT 404 26 -
QQFYDLLTGSMEIIR NR42_MOUSE 404 26 -
QQFYDLLTGSMEIIR NR42_HUMAN 404 26 -
QQFYDLLSGSLDVIR NR41_RAT 403 26 -
QQFYDLLSGSLDVIR NR41_MOUSE 407 26 -
QQFYDLLSGSLEVIR NR42_XENLA 383 26 -
QQFYDLLSGSLEVIR NR42_XENLA 383 26 -
QQFYNLLTASIDVSR O97726 452 23 -
QQFYNLLTASIDVSR NR43_HUMAN 435 23 -
QQFYNLLTASIDVSR NR43_RAT 437 23 -

Motif 7 width=21
Element Seqn Id St Int Rpt
RSKPGEGKLIFCSGLVLHRLQ NR41_HUMAN 454 35 -
RSKPAEGKLIFCSGLVLHRLQ NR41_CANFA 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_RAT 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_MOUSE 454 35 -
RSNPVEGKLIFCNGVVLHRLQ NR42_HUMAN 454 35 -
RSKPGEGKLIFCSGLVLHRLQ NR41_RAT 453 35 -
RSKPGEGKLIFCSGLVLHQLQ NR41_MOUSE 457 35 -
RSRPEEGKLIFCNGVVLHRTQ NR42_XENLA 433 35 -
RSRPEEGKLIFCNGVVLHRTQ NR42_XENLA 433 35 -
RSNTAEDKFVFCNGLVLHRLQ O97726 502 35 -
RSNTAEDKFVFCNGLVLHRLQ NR43_HUMAN 485 35 -
RSNTAEDKFVFCNGLVLHRLQ NR43_RAT 487 35 -

Motif 8 width=16
Element Seqn Id St Int Rpt
CARGFGDWIDSILAFS NR41_HUMAN 475 0 -
CARGFGDWIDSILAFS NR41_CANFA 475 0 -
CVRGFGEWIDSIVEFS NR42_RAT 475 0 -
CVRGFGEWIDSIVEFS NR42_MOUSE 475 0 -
CVRGFGEWIDSIVEFS NR42_HUMAN 475 0 -
CARGFGDWIDNILAFS NR41_RAT 474 0 -
CARGFGDWIDNILAFS NR41_MOUSE 478 0 -
CVRGFGEWIDSIIEFS NR42_XENLA 454 0 -
CVRGFGEWIDSIIEFS NR42_XENLA 454 0 -
CLRGFGEWLDSIKDFS O97726 523 0 -
CLRGFGEWLDSIKDFS NR43_HUMAN 506 0 -
CLRGFGEWLDSIKDFS NR43_RAT 508 0 -

Motif 9 width=18
Element Seqn Id St Int Rpt
PRRVEELQNRIASCLKEH NR41_HUMAN 521 30 -
PRRVEELQNRIASCLKEH NR41_CANFA 521 30 -
PKRVEELQNKIVNCLKDH NR42_RAT 521 30 -
PKRVEELQNKIVNCLKDH NR42_MOUSE 521 30 -
PKRVEELQNKIVNCLKDH NR42_HUMAN 521 30 -
PRRVEELQNRIASCLKEH NR41_RAT 520 30 -
PRRVEELQNRIASCLKEH NR41_MOUSE 524 30 -
PKKVEELQSQIINCLKEH NR42_XENLA 500 30 -
PKKVEELQSQIINCLKEH NR42_XENLA 500 30 -
PKRVEELCNKITSSLKEH O97726 569 30 -
PKRVEELCNKITSSLKDH NR43_HUMAN 552 30 -
PKRVEELCNKITSSLKDH NR43_RAT 554 30 -

Motif 10 width=21
Element Seqn Id St Int Rpt
RLLGKLPELRTLCTQGLQRIF NR41_HUMAN 554 15 -
RLLGKLPELRTLCTQGLQRIF NR41_CANFA 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_RAT 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_MOUSE 554 15 -
KLLGKLPELRTLCTQGLQRIF NR42_HUMAN 554 15 -
RLLGKLPELRTLCTQGLQRIF NR41_RAT 553 15 -
RLLGKLPELRTLCTQGLQRIF NR41_MOUSE 557 15 -
KLLGKLPELRTLCTQGLQRIF NR42_XENLA 533 15 -
KLLGKLPELRTLCTQGLQRIF NR42_XENLA 533 15 -
KVLRALVELRKICTLGLQRIF O97726 599 12 -
KVLGALVELRKICTLGLQRIF NR43_HUMAN 582 12 -
KVLRALVELRKICTQGLQRIF NR43_RAT 584 12 -

Motif 11 width=22
Element Seqn Id St Int Rpt
YLKLEDLVPPPPIIDKIFMDTL NR41_HUMAN 575 0 -
YLKLEDLVPPPPIVDKIFMDTL NR41_CANFA 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_RAT 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_MOUSE 575 0 -
YLKLEDLVPPPAIIDKLFLDTL NR42_HUMAN 575 0 -
CLKLEDLVPPPPIVDKIFMDTL NR41_RAT 574 0 -
CLKLEDLVPPPPIVDKIFMDTL NR41_MOUSE 578 0 -
YLKLEDLVPPPPIVDKIFMDTL NR42_XENLA 554 0 -
YLKLEDLVPPPPIVDKIFMDTL NR42_XENLA 554 0 -
YLKLEDLVSPPSIIDKLFLDTL O97726 620 0 -
YLKLEDLVSPPSIIDKLFLDTL NR43_HUMAN 603 0 -
YLKLEDLVSPPSVIDKLFLDTL NR43_RAT 605 0 -