SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01248

Identifier
TYPE1KERATIN  [View Relations]  [View Alignment]  
Accession
PR01248
No. of Motifs
5
Creation Date
09-DEC-1999
Title
Type I keratin signature
Database References

INTERPRO; IPR002957
Literature References
1. LAMMERS, P.J. AND BROWN, D.
The cytoskeleton.
http://www.nmsu.edu/~molbio/mcb520/lecture11.html
 
2. LODISH, H., BALTIMORE, D., BERK, A., ZIPURSKY, S.L., MATSUDAIRA, P.
AND DARNELL, J.
Microtubules and Intermediate Filaments
IN MOLECULAR CELL BIOLOGY, SCIENTIFIC AMERICAN BOOKS (NEW YORK), 1995,
PP.1107-1108.
 
3. MIDDLETON, K. AND DAVIS, A.
About intermediate filaments.
http://www.cytoskeleton.com/aif.htm

Documentation
Keratins are a well known group of intermediate filament proteins. Like 
actin filaments, keratins are flexible but provide a firm cell skeleton.
Unlike actin, however, no known keratins are associated with motor 
functions [1]. Approximately 10 keratins form the basis of hair or claw,
with a further 20 found in internal body cavity epithelia. They are also
found at desmosomes and hemi-desmosomes (cell/cell and cell/matrix contacts 
respectively) [2].
 
Type I keratins are a group of acidic intermediate filament proteins that
exist as chains of heterodimers with basic type II keratins [3]. Each type
I keratin consists of head-, rod- and tail-like structures, the rod being
constructed from three linked coils: 1A, 1B and 2. Type I proteins are 
associated with a number of inherited developmental disorders, such as 
baldness, beading of hair, and skin blistering.
 
TYPE1KERATIN is a 5-element fingerprint that provides a signature for type
I keratins. The fingerprint was derived from an initial alignment of 34
sequences: the motifs were drawn from the central and C-terminal portions
of the alignment - motifs 1 and 2 fall within coil 1B; motif 3 resides
within linker 12; and motifs 4 and 5 are located within coil 2 (the region 
encoded by PROSITE pattern IF (PS00226) lies between motif 5 and the 
C-terminus, within coil 2). Three iterations on SPTR37_10f were required to
reach convergence, at which point a true set comprising 53 sequences was
identified. Several partial matches were also found, all of which are 
intermediate filament proteins that mostly match motifs 2 and 5: Q90809 and 
Q90976 are chicken CP49 proteins; Q13515 is a highly diverent human protein;
Q28177 is a bovine phakinin; and O96754 is from Amphioxus.
Summary Information
  53 codes involving  5 elements
0 codes involving 4 elements
0 codes involving 3 elements
5 codes involving 2 elements
Composite Feature Index
55353535353
400000
300000
204105
12345
True Positives
K1C0_XENLA    K1C1_CARAU    K1C1_XENLA    K1C4_XENLA    
K1C5_XENLA K1CI_HUMAN K1CJ_BOVIN K1CJ_HUMAN
K1CJ_MOUSE K1CL_HUMAN K1CL_MOUSE K1CM_HUMAN
K1CM_MOUSE K1CN_HUMAN K1CO_HUMAN K1CO_MOUSE
K1CP_HUMAN K1CQ_HUMAN K1CR_HUMAN K1CR_MOUSE
K1CS_BOVIN K1CS_HUMAN K1CS_MOUSE K1CS_POTTR
K1CT_HUMAN K1CU_RAT K1CX_HUMAN K1M1_HUMAN
K1M1_MOUSE K1M1_SHEEP K1M2_HUMAN K1M2_MOUSE
K1M2_SHEEP K1M5_HUMAN O18740 O57607
O57611 O76009 O76010 O76011
O76012 O76013 O76014 O76015
O77727 O93256 Q07426 Q07427
Q14664 Q16402 Q9Z2K1 Q9Z2T8
Q9Z320
True Positive Partials
Codes involving 2 elements
O96754 Q13515 Q28177 Q90809
Q90976
Sequence Titles
K1C0_XENLA  KERATIN 3, TYPE I CYTOSKELETAL 51 KD (51 KD CYTOKERATIN) - XENOPUS LAEVIS (AFRIC 
K1C1_CARAU KERATIN, TYPE I CYTOSKELETAL 50 KD (GK50) - CARASSIUS AURATUS (GOLDFISH).
K1C1_XENLA KERATIN, TYPE I CYTOSKELETAL 47 KD - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
K1C4_XENLA KERATIN, TYPE I CYTOSKELETAL 47 KD - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
K1C5_XENLA KERATIN, TYPE I CYTOSKELETAL 47 KD - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
K1CI_HUMAN KERATIN, TYPE I CYTOSKELETAL 9 (CYTOKERATIN 9) (K9) (CK 9) - HOMO SAPIENS (HUMAN
K1CJ_BOVIN KERATIN, TYPE I CYTOSKELETAL VIB (CYTOKERATIN VIB) - BOS TAURUS (BOVINE).
K1CJ_HUMAN KERATIN, TYPE I CYTOSKELETAL 10 (CYTOKERATIN 10) (K10) (CK 10) - HOMO SAPIENS (H
K1CJ_MOUSE KERATIN, TYPE I CYTOSKELETAL 10 (CYTOKERATIN 10) (56 KD CYTOKERATIN) (KERATIN, T
K1CL_HUMAN KERATIN, TYPE I CYTOSKELETAL 12 (CYTOKERATIN 12) - HOMO SAPIENS (HUMAN).
K1CL_MOUSE KERATIN, TYPE I CYTOSKELETAL 12 (CYTOKERATIN 12) - MUS MUSCULUS (MOUSE).
K1CM_HUMAN KERATIN, TYPE I CYTOSKELETAL 13 (CYTOKERATIN 13) (K13) (CK 13) - HOMO SAPIENS (H
K1CM_MOUSE KERATIN, TYPE I CYTOSKELETAL 13 (CYTOKERATIN 13) (K13) (CK 13) (47 KD CYTOKERATI
K1CN_HUMAN KERATIN, TYPE I CYTOSKELETAL 14 (CYTOKERATIN 14) (K14) (CK 14) - HOMO SAPIENS (H
K1CO_HUMAN KERATIN, TYPE I CYTOSKELETAL 15 (CYTOKERATIN 15) (K15) (CK 15) - HOMO SAPIENS (H
K1CO_MOUSE KERATIN, TYPE I CYTOSKELETAL 15 (CYTOKERATIN 15) (K15) (CK 15) - MUS MUSCULUS (M
K1CP_HUMAN KERATIN, TYPE I CYTOSKELETAL 16 (CYTOKERATIN 16) (K16) (CK 16) - HOMO SAPIENS (H
K1CQ_HUMAN KERATIN, TYPE I CYTOSKELETAL 17 (CYTOKERATIN 17) (K17) (CK 17) (39.1) (VERSION 1
K1CR_HUMAN KERATIN, TYPE I CYTOSKELETAL 18 (CYTOKERATIN 18) (K18) (CK 18) - HOMO SAPIENS (H
K1CR_MOUSE KERATIN, TYPE I CYTOSKELETAL 18 (CYTOKERATIN 18) (CYTOKERATIN ENDO B) (KERATIN D
K1CS_BOVIN KERATIN, TYPE I CYTOSKELETAL 19 (CYTOKERATIN 19) (K19) (CK 19) - BOS TAURUS (BOV
K1CS_HUMAN KERATIN, TYPE I CYTOSKELETAL 19 (CYTOKERATIN 19) (K19) (CK 19) - HOMO SAPIENS (H
K1CS_MOUSE KERATIN, TYPE I CYTOSKELETAL 19 (CYTOKERATIN 19) (K19) (CK 19) - MUS MUSCULUS (M
K1CS_POTTR KERATIN, TYPE I CYTOSKELETAL 19 (CYTOKERATIN 19) (K19) (CK 19) - POTOROUS TRIDAC
K1CT_HUMAN KERATIN, TYPE I CYTOSKELETAL 20 (CYTOKERATIN 20) (K20) (CK 20) - HOMO SAPIENS (H
K1CU_RAT KERATIN, TYPE I CYTOSKELETAL 21 (CYTOKERATIN 21) (K21) - RATTUS NORVEGICUS (RAT)
K1CX_HUMAN KERATIN, TYPE I CYTOSKELETAL 17 (CYTOKERATIN 17) (K17) (CK 17) (VERSION 2) - HOM
K1M1_HUMAN KERATIN, TYPE I CUTICULAR HA1 (HAIR KERATIN, TYPE I HA1) - HOMO SAPIENS (HUMAN).
K1M1_MOUSE KERATIN, TYPE I CUTICULAR HA1 (HAIR KERATIN, TYPE I HA1) (HKA-1) - MUS MUSCULUS
K1M1_SHEEP KERATIN, TYPE I MICROFIBRILLAR 48 KD, COMPONENT 8C-1 (LOW-SULFUR KERATIN) - OVIS
K1M2_HUMAN KERATIN, TYPE I CUTICULAR HA2 (HAIR KERATIN, TYPE I HA2) - HOMO SAPIENS (HUMAN).
K1M2_MOUSE KERATIN, TYPE I CUTICULAR HA2 (HAIR KERATIN, TYPE I HA2) - MUS MUSCULUS (MOUSE).
K1M2_SHEEP KERATIN, TYPE I MICROFIBRILLAR, 47.6 KD (LOW-SULFUR KERATIN) - OVIS ARIES (SHEEP
K1M5_HUMAN KERATIN, TYPE I CUTICULAR HA5 (HAIR KERATIN, TYPE I HA5) - HOMO SAPIENS (HUMAN).
O18740 KERATIN - CANIS FAMILIARIS (DOG).
O57607 TYPE I KERATIN S5 - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
O57611 TYPE I KERATIN SK18 - SCYLIORHINUS STELLARIS.
O76009 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O76010 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O76011 KERATIN TYPE I - HOMO SAPIENS (HUMAN).
O76012 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O76013 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O76014 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O76015 KERATIN, TYPE I - HOMO SAPIENS (HUMAN).
O77727 K15 INTERMEDIATE FILAMENT TYPE I KERATIN - OVIS ARIES (SHEEP).
O93256 KERATIN-19 - GALLUS GALLUS (CHICKEN).
Q07426 KERATIN - CARASSIUS AURATUS (GOLDFISH).
Q07427 KERATIN - CARASSIUS AURATUS (GOLDFISH).
Q14664 KERATIN 10 - HOMO SAPIENS (HUMAN).
Q16402 TYPE I KERATIN 16 - HOMO SAPIENS (HUMAN).
Q9Z2K1 KERATIN 16 - MUS MUSCULUS (MOUSE).
Q9Z2T8 HAIR KERATIN ACIDIC 5 - MUS MUSCULUS (MOUSE).
Q9Z320 C29 - MUS MUSCULUS (MOUSE).

O96754 INTERMEDIATE FILAMENT PROTEIN E2 - BRANCHIOSTOMA LANCEOLATUM (COMMON LANCELET) (
Q13515 BEADED FILAMENT PROTEIN CP49 - HOMO SAPIENS (HUMAN).
Q28177 PHAKININ - BOS TAURUS (BOVINE).
Q90809 INTERMEDIATE FILAMENT PROTEIN CP49INS - GALLUS GALLUS (CHICKEN).
Q90976 INTERMEDIATE FILAMENT PROTEIN CP49 - GALLUS GALLUS (CHICKEN).
Scan History
SPTR37_10f 3  70   NSINGLE    
Initial Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
ARLAADDFRTKYET K1CN_HUMAN 192 192 -
ARLAADDFRTKFET K1CQ_HUMAN 161 161 -
ARLAADDFRTKYEA K1CX_HUMAN 192 192 -
ARLAADDFRLKYEN K1CO_HUMAN 184 184 -
ARLAADDFRLKYEN K1CM_MOUSE 175 175 -
ARLAADDFRLKYEN K1CJ_BOVIN 208 208 -
ARLAADDFRLKYEN K1CJ_MOUSE 224 224 -
ARLAADDFRLKYEN K1CJ_HUMAN 227 227 -
ARLAADDFRLKYEN K1CO_MOUSE 177 177 -
ARLAADDFRTKFET K1CS_POTTR 158 158 -
ARLAAEDFRMKYEN K1CL_MOUSE 200 200 -
ARLAVDDFRLKYEN K1CM_HUMAN 183 183 -
ARLAAEDFRMKYEN K1CL_HUMAN 207 207 -
ARLAADDFRTKFET K1CS_MOUSE 161 161 -
AKLAADDFRTKYET K1M5_HUMAN 145 145 -
AKLAADDFRTKYET K1M1_MOUSE 134 134 -
ARLAADDFRTKFET K1CS_BOVIN 157 157 -
AKLAADDFRTKYQT K1M1_HUMAN 134 134 -
ARLAADDFRTKFET K1CS_HUMAN 158 158 -
AKLAADDFRTKYET K1M1_SHEEP 133 133 -
AKLAADDFRLKFEN K1C4_XENLA 164 164 -
ARLAADDFRTNYEH K1CP_HUMAN 195 195 -
AKLAADDFRAKYEA K1M2_HUMAN 174 174 -
AKLASDDFRTKYET K1M2_SHEEP 133 133 -
AKLAADDFRTKYET K1M2_MOUSE 133 133 -
ARLAADDFRLKFEN K1C1_XENLA 152 152 -
AKLAAEDFRLKFET K1CU_RAT 152 152 -
AKLAAEDFRLKYET K1CT_HUMAN 148 148 -
ARLAADDFKMKFEN K1C0_XENLA 209 209 -
AKLATDDFKTKYEN K1C1_CARAU 194 194 -
AKLAADDFKIKYES K1C5_XENLA 152 152 -
TRMTLDDFRIKFEM K1CI_HUMAN 231 231 -
ARLAADDFRVKYET K1CR_HUMAN 156 156 -
ARLAADDFRVKYET K1CR_MOUSE 149 149 -

Motif 2 width=24
Element Seqn Id St Int Rpt
VEADINGLRRVLDELTLARADLEM K1CN_HUMAN 213 7 -
VEADINGLRRVLDELTLARADLEM K1CQ_HUMAN 182 7 -
VEADVNGLRRVLDELTLARTDLEM K1CX_HUMAN 213 7 -
VEADINGLRRVLDELTLARTDLEM K1CO_HUMAN 205 7 -
VEADINGLRRVLDELTLAKTDLEM K1CM_MOUSE 196 7 -
VEADINGLRRVLDELTLTKTDLEM K1CJ_BOVIN 229 7 -
VEADINGLRRVLDELTLSKSDLEM K1CJ_MOUSE 245 7 -
VEADINGLRRVLDELTLTKADLEM K1CJ_HUMAN 248 7 -
VEADINGLRRVLDELTLARTDLEM K1CO_MOUSE 198 7 -
VEADINGLRRVLDELTLARADLEM K1CS_POTTR 179 7 -
VEADINGLRRVLDELTLTRADLEA K1CL_MOUSE 221 7 -
VEADINGLRRVLDELTLSKTDLEM K1CM_HUMAN 204 7 -
VEADINGLRRVLDELTLTRTDLEM K1CL_HUMAN 228 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_MOUSE 182 7 -
VESDINGLRRILDDLTLCKSDLEA K1M5_HUMAN 166 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_MOUSE 155 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_BOVIN 178 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_HUMAN 155 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_HUMAN 179 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_SHEEP 154 7 -
VETDINGLRRVLDELTLARGDLEM K1C4_XENLA 185 7 -
VEAGVNGLCRVLDELTLARTDLEM K1CP_HUMAN 216 7 -
VEADINGLRRILDDLTLCKADLEA K1M2_HUMAN 195 7 -
VEADLNGLRRILDELTLCKSDLEA K1M2_SHEEP 154 7 -
VEADTNGLRRILDELTLNKADLEA K1M2_MOUSE 154 7 -
VEGDSNGLRRVLDELILARGDFEL K1C1_XENLA 173 7 -
VEADLQGLSKVYDDLTLQKTDLEI K1CU_RAT 173 7 -
VEADLQGLNKVFDDLTLHKTDLEI K1CT_HUMAN 169 7 -
VEADINGLRRVMDDLTLSKSDLES K1C0_XENLA 230 7 -
VEADIAGLKRLLDELTLARSDLEM K1C1_CARAU 215 7 -
AESDIVGLRRVLDELTLNKTDLEL K1C5_XENLA 173 7 -
VDADINGLRQVLDNLTMEKSDLEM K1CI_HUMAN 252 7 -
VENDIHGLRKVIDDTNITRLQLET K1CR_HUMAN 177 7 -
VESDIHGLRKVVDDTNITRLQLET K1CR_MOUSE 170 7 -

Motif 3 width=21
Element Seqn Id St Int Rpt
VNVEMDAAPGVDLSRILNEMR K1CN_HUMAN 267 30 -
INVEMDAAPGVDLSRILNEMR K1CQ_HUMAN 236 30 -
VNVEMDAAPGVDLSRILNEMR K1CX_HUMAN 267 30 -
VNVEMDAAPGVDLTRVLAEMR K1CO_HUMAN 259 30 -
VNVEMDATPGIDLTRVLAEMR K1CM_MOUSE 250 30 -
VNVEMNAAPGVDLTELLNNMR K1CJ_BOVIN 283 30 -
VNVEMNAAPGVDLTQLLNNMR K1CJ_MOUSE 299 30 -
VNVEMNAAPGVDLTQLLNNMR K1CJ_HUMAN 302 30 -
VNVEMDAAPGVDLTRMLAEMR K1CO_MOUSE 252 30 -
VSVEVDSAPGIDLAKILTDMR K1CS_POTTR 233 30 -
VNVEMDAAPGVDLTKVLNEMR K1CL_MOUSE 275 30 -
VNVEMDATPGIDLTRVLAEMR K1CM_HUMAN 258 30 -
VSVEMDAAPGVDLTRLLNDMR K1CL_HUMAN 282 30 -
VSVEVDSTPGVDLAKILSEMR K1CS_MOUSE 236 30 -
LNVEVDAAPPVDLNRVLEEMR K1M5_HUMAN 220 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_MOUSE 209 30 -
VSVEVDSAPGIDLAKILSDMR K1CS_BOVIN 232 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_HUMAN 209 30 -
VSVEVDSAPGTDLAKILSDMR K1CS_HUMAN 233 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_SHEEP 208 30 -
VNVEMDAAPGIDLNKILSDMR K1C4_XENLA 239 30 -
VNVEMDAAPGVDLSCILNEMR K1CP_HUMAN 270 30 -
LNIEVDAAPPVDLTRVLEEMR K1M2_HUMAN 249 30 -
LNVEVDAAPTVDLNHVLNETR K1M2_SHEEP 208 30 -
LNIEVDAAPPVDLTRMLEEVR K1M2_MOUSE 208 30 -
VSVEMDAALGVDLTSILNNMR K1C1_XENLA 227 30 -
VNVEVDAAPGLNLGEIMNEMR K1CU_RAT 227 30 -
VNVEVDAAPGLNLGVIMNEMR K1CT_HUMAN 223 30 -
VNVEMNAAPSSDLTKILNDMR K1C0_XENLA 284 30 -
VNVEVDAAPQEDLSRVMAEIR K1C1_CARAU 269 30 -
VDVQVDSAPPVDLAQIMADVR K1C5_XENLA 227 30 -
VNVEINVAPGKDLTKTLNDMR K1CI_HUMAN 306 30 -
LTVEVDAPKSQDLAKIMADIR K1CR_HUMAN 232 31 -
LTVEVDAPKSQDLSKIMADIR K1CR_MOUSE 225 31 -

Motif 4 width=16
Element Seqn Id St Int Rpt
NLEIELQSQLSMKASL K1CN_HUMAN 339 51 -
ALEIELQSQLSMKASL K1CQ_HUMAN 308 51 -
GLEIELQSQLRMKASL K1CX_HUMAN 339 51 -
ELEIELQSQLSMKAGL K1CO_HUMAN 331 51 -
GLEIELQSQLSMKAGL K1CM_MOUSE 322 51 -
GLEIELQSQLALKQSL K1CJ_BOVIN 355 51 -
GLEIELQSQLALKQSL K1CJ_MOUSE 371 51 -
ALEIELQSQLALKQSL K1CJ_HUMAN 374 51 -
GLEIELQSQLSMKAGL K1CO_MOUSE 324 51 -
GLEIELQSQLSMKAAL K1CS_POTTR 305 51 -
NLEIELQSQLAMKSSL K1CL_MOUSE 347 51 -
GLEIELQSQLSMKAGL K1CM_HUMAN 330 51 -
NLEIELQSQLAMKKSL K1CL_HUMAN 354 51 -
GLEIELQSQLSMKAAL K1CS_MOUSE 308 51 -
ALEIELQAQHSMRDAL K1M5_HUMAN 292 51 -
ALEIELQAQHCMRNSL K1M1_MOUSE 281 51 -
GLEIELQSQLSMKAAL K1CS_BOVIN 304 51 -
ALEIELQAQHNLRDSL K1M1_HUMAN 281 51 -
GLEIELQSQLSMKAAL K1CS_HUMAN 305 51 -
ALEVELQAQHNLRDSL K1M1_SHEEP 280 51 -
SLEIELQSQLAMKKSL K1C4_XENLA 311 51 -
GLEMELQSQLSIKASL K1CP_HUMAN 342 51 -
TLEIELQAQHSLRDSL K1M2_HUMAN 321 51 -
ALEVELQAQHNLRDSL K1M2_SHEEP 280 51 -
TLEIELQAQHSLRDSL K1M2_MOUSE 280 51 -
SLEIELQSQLAMKQSV K1C1_XENLA 299 51 -
TLEIELQSQLSMKESL K1CU_RAT 299 51 -
SLEIELQSHLSMKESL K1CT_HUMAN 295 51 -
SLEIELQSQLAMKKSL K1C0_XENLA 356 51 -
GLEIELQSELSKKRSL K1C1_CARAU 341 51 -
SLEIELQSLLSMKGAL K1C5_XENLA 299 51 -
ELEIELQSQLSKKAAL K1CI_HUMAN 378 51 -
SLEIDLDSMRNLKASL K1CR_HUMAN 304 51 -
TLEIDLDSMKNQNINL K1CR_MOUSE 297 51 -

Motif 5 width=27
Element Seqn Id St Int Rpt
YCMQLAQIQEMIGSVEEQLAQLRCEME K1CN_HUMAN 365 10 -
YCVQLSQIQGLIGSVEEQLAQLRCEME K1CQ_HUMAN 334 10 -
YCMQLSQIQGLIGSVEEQLAQLRCEME K1CX_HUMAN 365 10 -
YATQLQQIQGLIGGLEAQLSELRCEME K1CO_HUMAN 357 10 -
YALQLQQIQGLISSIEAQLSELRSEME K1CM_MOUSE 348 10 -
YCVQLSQIQSQISSLEEQLQQIRAETE K1CJ_BOVIN 381 10 -
YCVQLSQIQSQISALEEQLQQIRAETE K1CJ_MOUSE 397 10 -
YCVQLSQIQAQISALEEQLQQIRAETE K1CJ_HUMAN 400 10 -
YATQLQQIQGVITGLETQLSELHSQME K1CO_MOUSE 350 10 -
YGVQLSQIQALISNIESQLSDIRADME K1CS_POTTR 331 10 -
YCCQLSQVQQLIGSLEEQLQQVRADAE K1CL_MOUSE 373 10 -
YALQLQQIQGLISSIEAQLSELRSEME K1CM_HUMAN 356 10 -
YCAQLSQVQQLISNLEAQLLQVRADAE K1CL_HUMAN 380 10 -
YGVQLSQIQSVISGFEAQLSDVRADIE K1CS_MOUSE 334 10 -
YSSQLAQMQCMITNVEAQLAEIRADLE K1M5_HUMAN 318 10 -
YSSQLSQVQCLITNVESQLGEIRADLE K1M1_MOUSE 307 10 -
FGAQLAQIQALISGIEAQLSDVRADTE K1CS_BOVIN 330 10 -
YSSQLSQVQSLITNVESQLAEIRSDLE K1M1_HUMAN 307 10 -
FGAQLAHIQALISGIEAQLADVRADSE K1CS_HUMAN 331 10 -
YSCQLNQVQSLISNVESQLAEIRGDLE K1M1_SHEEP 306 10 -
YGAQLQTIQFSLRSLEEQLLQIRSDME K1C4_XENLA 337 10 -
YCMQLSQIQGLIGSVEEQLAQLCCEME K1CP_HUMAN 368 10 -
YSSQLAQMQCMITNVEAQLAEIRAELE K1M2_HUMAN 347 10 -
YSCQLNQVQSLIVSVESQLAEIRSDLE K1M2_SHEEP 306 10 -
FTSQLSQMQCMITNVESQLSDIRCDLE K1M2_MOUSE 306 10 -
YSSQLQQIQNTIGSLEEQLLQIRSDME K1C1_XENLA 325 10 -
YASQLAAIQEMLSSLEAQLMQIRSDTE K1CU_RAT 325 10 -
YSSQLANLQSLLSSLEAQLMQIRSNME K1CT_HUMAN 321 10 -
FCMKLSRLQEMIVNVEEQIARLKGESE K1C0_XENLA 382 10 -
YSIQLTQLQARVTSLEEQIVHLRGDMD K1C1_CARAU 367 10 -
YGAQLNHLQAMITQVEMELQNLRSDAD K1C5_XENLA 325 10 -
YCGQLQMIQEQISNLEAQITDVRQEIE K1CI_HUMAN 404 10 -
YALQMEQLNGILLHLESELAQTRAEGQ K1CR_HUMAN 330 10 -
YKAQMEQLNGVLLHLESELAQTRAEGQ K1CR_MOUSE 323 10 -
Final Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
ARLAADDFRTKYET K1CN_HUMAN 192 192 -
ARLAADDFRTKYEH Q16402 195 195 -
ARLAADDFRTKYEN Q9Z2K1 191 191 -
ARLAADDFRTKFET K1CQ_HUMAN 161 161 -
ARLAADDFRTKYEA K1CX_HUMAN 192 192 -
ARLAADDFRLKYEN O77727 182 182 -
ARLAADDFRLKYEN K1CO_HUMAN 184 184 -
ARLAADDFRLKYEN K1CM_MOUSE 175 175 -
ARLAADDFRLKYEN K1CJ_BOVIN 208 208 -
ARLAADDFRLKYEN K1CJ_MOUSE 224 224 -
ARLAADDFRLKYEN K1CJ_HUMAN 227 227 -
ARLAADDFRLKYEN K1CO_MOUSE 177 177 -
ARLAADDFRTKFET K1CS_POTTR 158 158 -
ARLAAEDFRMKYEN K1CL_MOUSE 200 200 -
ARLAVDDFRLKYEN K1CM_HUMAN 183 183 -
ARLAADDFRLKYEN Q14664 220 220 -
AKLAADDFRTKYET O76013 171 171 -
ARLAAEDFRMKYEN K1CL_HUMAN 207 207 -
ARLAADDFRTKFET K1CS_MOUSE 161 161 -
AKLAADDFRTKYET K1M5_HUMAN 145 145 -
AKLAADDFRTKYET O76012 145 145 -
AKLAADDFRTKYET K1M1_MOUSE 134 134 -
ARLAADDFRTKFET K1CS_BOVIN 157 157 -
ARLAADDFKTKFET O93256 172 172 -
AKLAADDFRTKYET Q9Z2T8 145 145 -
AKLAADDFRTKYQT K1M1_HUMAN 134 134 -
ARLAADDFRTKFET K1CS_HUMAN 158 158 -
AKLASDDFRTKYET O76009 134 134 -
AKLAADDFRTKYET K1M1_SHEEP 133 133 -
AKLAADDFRLKFEN K1C4_XENLA 164 164 -
ARLAADDFRTNYEH K1CP_HUMAN 195 195 -
AKLAADDFRAKYEA K1M2_HUMAN 174 174 -
AKLAADDFRTKYQT O76010 134 134 -
ARLTADDFRMKYEN Q9Z320 156 156 -
AKLAADDFRVKYEN Q07426 183 183 -
AKLASDDFRTKYET K1M2_SHEEP 133 133 -
AKLAADDFRTKYET K1M2_MOUSE 133 133 -
ARLAADDFRLKFEN K1C1_XENLA 152 152 -
AKLASDDFRSKYQT O76011 134 134 -
AKLAAEDFRLKFET K1CU_RAT 152 152 -
AKLAAEDFRLKYET K1CT_HUMAN 148 148 -
ARLAADDFKMKFEN K1C0_XENLA 209 209 -
AKLATDDFKTKYEN K1C1_CARAU 194 194 -
AKLAADDFKIKYES K1C5_XENLA 152 152 -
TRMTLDDFRIKFEM K1CI_HUMAN 231 231 -
AKLAADDFRIKLES O76014 140 140 -
ARLAADDFRVKWES O57611 144 144 -
AKLAADDFRIKLES O76015 140 140 -
TRMTLDDIRMKCDI O18740 216 216 -
ARLAADDFRVKYET K1CR_HUMAN 156 156 -
ARLAADDFRVKFES O57607 166 166 -
ARLAADDFRVKYDS Q07427 165 165 -
ARLAADDFRVKYET K1CR_MOUSE 149 149 -

Motif 2 width=24
Element Seqn Id St Int Rpt
VEADINGLRRVLDELTLARADLEM K1CN_HUMAN 213 7 -
VEADVNGLRRVLDELTLARTDLEM Q16402 216 7 -
VEGDINGLRKVLDELTLSRADLEM Q9Z2K1 212 7 -
VEADINGLRRVLDELTLARADLEM K1CQ_HUMAN 182 7 -
VEADVNGLRRVLDELTLARTDLEM K1CX_HUMAN 213 7 -
VEADINGLRRVLDELTLTKTDLEM O77727 203 7 -
VEADINGLRRVLDELTLARTDLEM K1CO_HUMAN 205 7 -
VEADINGLRRVLDELTLAKTDLEM K1CM_MOUSE 196 7 -
VEADINGLRRVLDELTLTKTDLEM K1CJ_BOVIN 229 7 -
VEADINGLRRVLDELTLSKSDLEM K1CJ_MOUSE 245 7 -
VEADINGLRRVLDELTLTKADLEM K1CJ_HUMAN 248 7 -
VEADINGLRRVLDELTLARTDLEM K1CO_MOUSE 198 7 -
VEADINGLRRVLDELTLARADLEM K1CS_POTTR 179 7 -
VEADINGLRRVLDELTLTRADLEA K1CL_MOUSE 221 7 -
VEADINGLRRVLDELTLSKTDLEM K1CM_HUMAN 204 7 -
VEADINGLRRVLDELTLTQADLEM Q14664 241 7 -
VEADINGLRRILDELTLCKADLEA O76013 192 7 -
VEADINGLRRVLDELTLTRTDLEM K1CL_HUMAN 228 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_MOUSE 182 7 -
VESDINGLRRILDDLTLCKSDLEA K1M5_HUMAN 166 7 -
VESDINGLRRILDDLTLCKSDLEA O76012 166 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_MOUSE 155 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_BOVIN 178 7 -
VEADINGLRRVLDELTLARTDLEL O93256 193 7 -
VEADINGLRRILDDLTLCKADLEA Q9Z2T8 166 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_HUMAN 155 7 -
VEADINGLRRVLDELTLARTDLEM K1CS_HUMAN 179 7 -
VESDINGLRRILDELTLCRSDLEA O76009 155 7 -
VESDINGLRRILDELTLCKSDLEA K1M1_SHEEP 154 7 -
VETDINGLRRVLDELTLARGDLEM K1C4_XENLA 185 7 -
VEAGVNGLCRVLDELTLARTDLEM K1CP_HUMAN 216 7 -
VEADINGLRRILDDLTLCKADLEA K1M2_HUMAN 195 7 -
VESDINSLRRILDELTLCRSDLEA O76010 155 7 -
VDADINGLRRVLDELTLCRTDLEV Q9Z320 177 7 -
VEADIAGLRRVLDELTMARSDLEM Q07426 204 7 -
VEADLNGLRRILDELTLCKSDLEA K1M2_SHEEP 154 7 -
VEADTNGLRRILDELTLNKADLEA K1M2_MOUSE 154 7 -
VEGDSNGLRRVLDELILARGDFEL K1C1_XENLA 173 7 -
VESDINSIRRILDELTLCKSDLES O76011 155 7 -
VEADLQGLSKVYDDLTLQKTDLEI K1CU_RAT 173 7 -
VEADLQGLNKVFDDLTLHKTDLEI K1CT_HUMAN 169 7 -
VEADINGLRRVMDDLTLSKSDLES K1C0_XENLA 230 7 -
VEADIAGLKRLLDELTLARSDLEM K1C1_CARAU 215 7 -
AESDIVGLRRVLDELTLNKTDLEL K1C5_XENLA 173 7 -
VDADINGLRQVLDNLTMEKSDLEM K1CI_HUMAN 252 7 -
VEADKCGTQKLLDDATLAKADLEA O76014 161 7 -
VENDINGLRKVIDDTNIGRLHLET O57611 165 7 -
VEADKCGTQKLLDDATLAKADLEA O76015 161 7 -
VNADINGLRKVLDDLTMQKSDLEM O18740 237 7 -
VENDIHGLRKVIDDTNITRLQLET K1CR_HUMAN 177 7 -
VEADIVGLRKVIDDTNMGRMNLES O57607 187 7 -
VEADIAGLRKVIDDTNMNRMNLES Q07427 186 7 -
VESDIHGLRKVVDDTNITRLQLET K1CR_MOUSE 170 7 -

Motif 3 width=21
Element Seqn Id St Int Rpt
VNVEMDAAPGVDLSRILNEMR K1CN_HUMAN 267 30 -
VNVEMDAAPGVDLSRILNEMR Q16402 270 30 -
VNVEMDAAPGVDLSRILNEMR Q9Z2K1 266 30 -
INVEMDAAPGVDLSRILNEMR K1CQ_HUMAN 236 30 -
VNVEMDAAPGVDLSRILNEMR K1CX_HUMAN 267 30 -
VNVEMDAAPGVDLTRVLSEMR O77727 257 30 -
VNVEMDAAPGVDLTRVLAEMR K1CO_HUMAN 259 30 -
VNVEMDATPGIDLTRVLAEMR K1CM_MOUSE 250 30 -
VNVEMNAAPGVDLTELLNNMR K1CJ_BOVIN 283 30 -
VNVEMNAAPGVDLTQLLNNMR K1CJ_MOUSE 299 30 -
VNVEMNAAPGVDLTQLLNNMR K1CJ_HUMAN 302 30 -
VNVEMDAAPGVDLTRMLAEMR K1CO_MOUSE 252 30 -
VSVEVDSAPGIDLAKILTDMR K1CS_POTTR 233 30 -
VNVEMDAAPGVDLTKVLNEMR K1CL_MOUSE 275 30 -
VNVEMDATPGIDLTRVLAEMR K1CM_HUMAN 258 30 -
VNVEMNAAPGVDLTQLLNNMR Q14664 295 30 -
LNVEVDAAPPVDLNKILEDMR O76013 246 30 -
VSVEMDAAPGVDLTRLLNDMR K1CL_HUMAN 282 30 -
VSVEVDSTPGVDLAKILSEMR K1CS_MOUSE 236 30 -
LNVEVDAAPPVDLNRVLEEMR K1M5_HUMAN 220 30 -
LNVEVDAAPPVDLNRVLEEMR O76012 220 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_MOUSE 209 30 -
VSVEVDSAPGIDLAKILSDMR K1CS_BOVIN 232 30 -
VSVEVDSAPGIDLSKILADMR O93256 247 30 -
LNVEVDAAPPVDLNRVLDEMR Q9Z2T8 220 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_HUMAN 209 30 -
VSVEVDSAPGTDLAKILSDMR K1CS_HUMAN 233 30 -
LNVEVDAAPTVDLNQVLNETR O76009 209 30 -
LNVEVDAAPTVDLNRVLNETR K1M1_SHEEP 208 30 -
VNVEMDAAPGIDLNKILSDMR K1C4_XENLA 239 30 -
VNVEMDAAPGVDLSCILNEMR K1CP_HUMAN 270 30 -
LNIEVDAAPPVDLTRVLEEMR K1M2_HUMAN 249 30 -
LNVEVDAAPAVDLNQVLNETR O76010 209 30 -
VNVEMNAAPGVDLTVLLNNMR Q9Z320 231 30 -
VNVEVDAAPQEDLTKIMAEIR Q07426 258 30 -
LNVEVDAAPTVDLNHVLNETR K1M2_SHEEP 208 30 -
LNIEVDAAPPVDLTRMLEEVR K1M2_MOUSE 208 30 -
VSVEMDAALGVDLTSILNNMR K1C1_XENLA 227 30 -
LNVEVDTAPTVDLNQVLNETR O76011 209 30 -
VNVEVDAAPGLNLGEIMNEMR K1CU_RAT 227 30 -
VNVEVDAAPGLNLGVIMNEMR K1CT_HUMAN 223 30 -
VNVEMNAAPSSDLTKILNDMR K1C0_XENLA 284 30 -
VNVEVDAAPQEDLSRVMAEIR K1C1_CARAU 269 30 -
VDVQVDSAPPVDLAQIMADVR K1C5_XENLA 227 30 -
VNVEINVAPGKDLTKTLNDMR K1CI_HUMAN 306 30 -
FRIELDIEPTIDLNRVLGEMR O76014 215 30 -
VHVEVDSAPGPDLSKVLAEIR O57611 220 31 -
LRIELDIEPTIDLNRVLGEMR O76015 215 30 -
VNVEMNAAPGRDLTKILNDMR O18740 291 30 -
LTVEVDAPKSQDLAKIMADIR K1CR_HUMAN 232 31 -
VQVDVDAPKGQDLAAIMAEVR O57607 242 31 -
VQVDVDAPKGQDLAKIMEEIR Q07427 241 31 -
LTVEVDAPKSQDLSKIMADIR K1CR_MOUSE 225 31 -

Motif 4 width=16
Element Seqn Id St Int Rpt
NLEIELQSQLSMKASL K1CN_HUMAN 339 51 -
GLEIELQSQLSMKASL Q16402 342 51 -
GLEIELQSQLSMKASL Q9Z2K1 338 51 -
ALEIELQSQLSMKASL K1CQ_HUMAN 308 51 -
GLEIELQSQLRMKASL K1CX_HUMAN 339 51 -
GLEIELQSQLSMKAGL O77727 329 51 -
ELEIELQSQLSMKAGL K1CO_HUMAN 331 51 -
GLEIELQSQLSMKAGL K1CM_MOUSE 322 51 -
GLEIELQSQLALKQSL K1CJ_BOVIN 355 51 -
GLEIELQSQLALKQSL K1CJ_MOUSE 371 51 -
ALEIELQSQLALKQSL K1CJ_HUMAN 374 51 -
GLEIELQSQLSMKAGL K1CO_MOUSE 324 51 -
GLEIELQSQLSMKAAL K1CS_POTTR 305 51 -
NLEIELQSQLAMKSSL K1CL_MOUSE 347 51 -
GLEIELQSQLSMKAGL K1CM_HUMAN 330 51 -
ALEIELQSQLALKQSL Q14664 367 51 -
ALEIELQAQHSMRNSL O76013 318 51 -
NLEIELQSQLAMKKSL K1CL_HUMAN 354 51 -
GLEIELQSQLSMKAAL K1CS_MOUSE 308 51 -
ALEIELQAQHSMRDAL K1M5_HUMAN 292 51 -
ALEIELQAQHSMRDAL O76012 292 51 -
ALEIELQAQHCMRNSL K1M1_MOUSE 281 51 -
GLEIELQSQLSMKAAL K1CS_BOVIN 304 51 -
GLEIELQSQLSMKGAL O93256 319 51 -
SLEIELQAQQSMRDAL Q9Z2T8 292 51 -
ALEIELQAQHNLRDSL K1M1_HUMAN 281 51 -
GLEIELQSQLSMKAAL K1CS_HUMAN 305 51 -
ALEIELQAQHNLRDSL O76009 281 51 -
ALEVELQAQHNLRDSL K1M1_SHEEP 280 51 -
SLEIELQSQLAMKKSL K1C4_XENLA 311 51 -
GLEMELQSQLSIKASL K1CP_HUMAN 342 51 -
TLEIELQAQHSLRDSL K1M2_HUMAN 321 51 -
ALEIELQAQHNLRYSL O76010 281 51 -
TLEIELQSLLAMKHSL Q9Z320 303 51 -
GLEIELQSQLSMKASL Q07426 330 51 -
ALEVELQAQHNLRDSL K1M2_SHEEP 280 51 -
TLEIELQAQHSLRDSL K1M2_MOUSE 280 51 -
SLEIELQSQLAMKQSV K1C1_XENLA 299 51 -
ALEIELQAQHNLRDSL O76011 281 51 -
TLEIELQSQLSMKESL K1CU_RAT 299 51 -
SLEIELQSHLSMKESL K1CT_HUMAN 295 51 -
SLEIELQSQLAMKKSL K1C0_XENLA 356 51 -
GLEIELQSELSKKRSL K1C1_CARAU 341 51 -
SLEIELQSLLSMKGAL K1C5_XENLA 299 51 -
ELEIELQSQLSKKAAL K1CI_HUMAN 378 51 -
ALEVERQAQHTLKDCL O76014 287 51 -
SLEVELESLLSMKNSL O57611 292 51 -
ALEVERQAQHTLKDCL O76015 287 51 -
EMEIELQSQLSKKSAL O18740 363 51 -
SLEIDLDSMRNLKASL K1CR_HUMAN 304 51 -
TLEIELDSQKSLKGSL O57607 314 51 -
TLEIELESQRNLKGSL Q07427 313 51 -
TLEIDLDSMKNQNINL K1CR_MOUSE 297 51 -

Motif 5 width=27
Element Seqn Id St Int Rpt
YCMQLAQIQEMIGSVEEQLAQLRCEME K1CN_HUMAN 365 10 -
YCMQLSQIQGLIGSVEEQLAQLRCEME Q16402 368 10 -
YCMQLSQIQGLISSVEEQLAQLRCEME Q9Z2K1 364 10 -
YCVQLSQIQGLIGSVEEQLAQLRCEME K1CQ_HUMAN 334 10 -
YCMQLSQIQGLIGSVEEQLAQLRCEME K1CX_HUMAN 365 10 -
YAAQLQQIQGLISSIEAQLSELRSEME O77727 355 10 -
YATQLQQIQGLIGGLEAQLSELRCEME K1CO_HUMAN 357 10 -
YALQLQQIQGLISSIEAQLSELRSEME K1CM_MOUSE 348 10 -
YCVQLSQIQSQISSLEEQLQQIRAETE K1CJ_BOVIN 381 10 -
YCVQLSQIQSQISALEEQLQQIRAETE K1CJ_MOUSE 397 10 -
YCVQLSQIQAQISALEEQLQQIRAETE K1CJ_HUMAN 400 10 -
YATQLQQIQGVITGLETQLSELHSQME K1CO_MOUSE 350 10 -
YGVQLSQIQALISNIESQLSDIRADME K1CS_POTTR 331 10 -
YCCQLSQVQQLIGSLEEQLQQVRADAE K1CL_MOUSE 373 10 -
YALQLQQIQGLISSIEAQLSELRSEME K1CM_HUMAN 356 10 -
YCVQLSQIQAQISALEEQLQEIRAETE Q14664 393 10 -
YSSQLAQMQCLISNVEAQLSEIRCDLE O76013 344 10 -
YCAQLSQVQQLISNLEAQLLQVRADAE K1CL_HUMAN 380 10 -
YGVQLSQIQSVISGFEAQLSDVRADIE K1CS_MOUSE 334 10 -
YSSQLAQMQCMITNVEAQLAEIRADLE K1M5_HUMAN 318 10 -
YSSQLAQMQCMITNVEAQLAEIRADLE O76012 318 10 -
YSSQLSQVQCLITNVESQLGEIRADLE K1M1_MOUSE 307 10 -
FGAQLAQIQALISGIEAQLSDVRADTE K1CS_BOVIN 330 10 -
YGAQLAQIQDMIGSIEAQLAELRADME O93256 345 10 -
YSSQLAQMQCMIGNVESQLGEIRADLE Q9Z2T8 318 10 -
YSSQLSQVQSLITNVESQLAEIRSDLE K1M1_HUMAN 307 10 -
FGAQLAHIQALISGIEAQLADVRADSE K1CS_HUMAN 331 10 -
YSSQLSQVQRLITNVESQLAEIRSDLE O76009 307 10 -
YSCQLNQVQSLISNVESQLAEIRGDLE K1M1_SHEEP 306 10 -
YGAQLQTIQFSLRSLEEQLLQIRSDME K1C4_XENLA 337 10 -
YCMQLSQIQGLIGSVEEQLAQLCCEME K1CP_HUMAN 368 10 -
YSSQLAQMQCMITNVEAQLAEIRAELE K1M2_HUMAN 347 10 -
YSSQLSQVQSLITNVESQLAEIRSDLE O76010 307 10 -
YCTQLAQIQAQISALEEQLHQVRTETE Q9Z320 329 10 -
YSSMLSGFQMQVTSMEQQLGQLRGDLE Q07426 356 10 -
YSCQLNQVQSLIVSVESQLAEIRSDLE K1M2_SHEEP 306 10 -
FTSQLSQMQCMITNVESQLSDIRCDLE K1M2_MOUSE 306 10 -
YSSQLQQIQNTIGSLEEQLLQIRSDME K1C1_XENLA 325 10 -
YSSQLSQVQSLITNVESQLAEIRCDLE O76011 307 10 -
YASQLAAIQEMLSSLEAQLMQIRSDTE K1CU_RAT 325 10 -
YSSQLANLQSLLSSLEAQLMQIRSNME K1CT_HUMAN 321 10 -
FCMKLSRLQEMIVNVEEQIARLKGESE K1C0_XENLA 382 10 -
YSIQLTQLQARVTSLEEQIVHLRGDMD K1C1_CARAU 367 10 -
YGAQLNHLQAMITQVEMELQNLRSDAD K1C5_XENLA 325 10 -
YCGQLQMIQEQISNLEAQITDVRQEIE K1CI_HUMAN 404 10 -
YGTELAQMQSLISNLEEQLSEIRADLE O76014 313 10 -
YEMELQTINGMIAKLEADLHQIRGDMQ O57611 318 10 -
FGTELAQMQSLISNVEEQLSEIRADLE O76015 313 10 -
YCGQLQQLQEQIRSLEGQITEIRGEIE O18740 389 10 -
YALQMEQLNGILLHLESELAQTRAEGQ K1CR_HUMAN 330 10 -
YNMEMESLNKILVGLESELTNLRSNIQ O57607 340 10 -
YNMEIESLNAVTMQLEAELTQLRNNIQ Q07427 339 10 -
YKAQMEQLNGVLLHLESELAQTRAEGQ K1CR_MOUSE 323 10 -