SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR01041

Identifier
TRNASYNTHMET  [View Relations]  [View Alignment]  
Accession
PR01041
No. of Motifs
6
Creation Date
11-DEC-1998  (UPDATE 28-JUN-1999)
Title
Methionyl-tRNA synthetase signature
Database References
PRINTS; PR90000 TRNASYNTH; PR90001 TRNASYNTHCLI
PROSITE; PS00178 AA_TRNA_LIGASE_I
INTERPRO; IPR002304
PDB; 1MEA; 1MED
SCOP; 1MEA; 1MED
Literature References
1. LODISH, H., BALTIMORE, D., BERK, A., ZIPURSKY, S.L., MATSUDAIRA, P. AND
DARNELL, J.
Nucleic Acids, the Genetic Code, and Protein Synthesis. 
IN MOLECULAR CELL BIOLOGY, SCIENTIFIC AMERICAN BOOKS (NEW YORK), 1995,
PP.126-128.
 
2. DELARUE, M.
Aminoacyl-tRNA synthetases.
CURR.OPIN.STRUCT.BIOL. 5 48-55 (1995).
 
3. PERONA, J.J., ROULD, M. AND STEITZ, T.A.
Structural Basis for Transfer RNA Aminoacylation by Escherichia coli
Glutaminyl-tRNA Synthetase.
BIOCHEMISTRY 32 8758-8771 (1993).

Documentation
Appropriate attachment of an amino acid to its cognate tRNA is the key to
faithful translation of the genetic code. The family of enzymes responsible
for this is the aminoacyl-tRNA synthetases (AATRSs) (EC 6.1.1.-).
 
AATRSs catalyse a two-step reaction:
 
(1) Enzyme + amino acid + ATP ---> Enzyme(aminoacyl-AMP) + PPi
 
(2) tRNA + Enzyme(aminoacyl-AMP) ---> aminoacyl-tRNA + AMP + Enzyme
 
In the first step, they form an aminoacyl-adenylate, in which the carboxyl
of the amino acid is linked to the alpha-phosphate of ATP, by displacing
the pyrophosphate. When the correct tRNA is bound, the aminoacyl group is
transferred to the 2'- or 3'-terminal OH of the tRNA at the expense of AMP
[1].
 
Based on structural and sequence comparisons, this group of at least 20
proteins (in prokaryotes there are approximately 20, but in eukaryotes
there are usually 2 forms for each amino acid; namely, the cytosolic and
mitochondrial forms) can be divided into two classes.
 
Class I AATRSs contain a characteristic Rossman fold and are mostly
monomeric. At the primary structure level, two highly-conserved motifs
are observed, `HIGH' and `KMSKS' [2,3]; these are associated with the ATP-
binding site.
 
Class II AATRSs share an anti-parallel beta-sheet formation, flanked by
alpha-helices [3], and are mostly dimeric or multimeric.
 
Further distinction between the two classes is evident when the reaction
mechanisms are investigated. In reactions catalysed by the class I AATRSs,
the aminoacyl group is coupled to the 2'-hydroxyl of the tRNA, while, in
class II reactions, the 3'-hydroxyl site is preferred.
 
Methionly-tRNA synthetase (EC 6.1.1.10) is specific to methionine and 
belongs to class I.
 
TRNASYNTHMET is a 6-element fingerprint that provides a signature for the
methionyl-tRNA synthetases. The fingerprint was derived from an initial
alignment of 11 sequences: the motifs were drawn from the N-terminal and
central portions of the alignment - motif 1 spans part of the region encoded
by the PROSITE pattern AA_TRNA_LIGASE_I (PS00178), which contains the `HIGH'
consensus sequence; a zinc binding site lies between motifs 3 and 4. Three 
iterations on OWL31.1 were required to reach convergence, at which point a 
true set comprising 27 sequences was identified. Two partial matches were 
also found, SYM_MYCPU and AB006140, both of which are fragments that lack 
the portion of sequence bearing motif 6. 
 
An update on SPTR37_9f identified a true set of 27 sequences, and 11
partial matches.
Summary Information
  27 codes involving  6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
11 codes involving 2 elements
Composite Feature Index
6272727272727
5000000
4000000
3000000
21190002
123456
True Positives
O13634        O14000        O23761        O33925        
O58721 O67298 O74634 O84035
SYMC_YEAST SYMM_YEAST SYM_ARCFU SYM_BACST
SYM_BACSU SYM_BORBU SYM_CAEEL SYM_ECOLI
SYM_HAEIN SYM_HELPY SYM_HUMAN SYM_METJA
SYM_METTH SYM_MYCGE SYM_MYCPN SYM_MYCTU
SYM_SYNY3 SYM_THETH SYM_TREPA
True Positive Partials
Codes involving 2 elements
O75005 Q12019 SYIM_YEAST SYI_ECOLI
SYI_HELPY SYI_SYNY3 SYLM_SACDO SYV_ARCFU
SYV_METJA SYV_METTH YLJ6_CAEEL
Sequence Titles
O13634      METHIONYL-TRNA SYNTHETASE - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
O14000 PUTATIVE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O23761 METRS (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METHIONYL-TRNA SYNTHETASE) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O33925 METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - THERMOTOGA MARITIMA.
O58721 723AA LONG HYPOTHETICAL METHIONYL-TRNA SYNTHETASE - PYROCOCCUS HORIKOSHII.
O67298 METHIONYL-TRNA SYNTHETASE ALPHA SUBUNIT - AQUIFEX AEOLICUS.
O74634 METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.10) (METHIONINE-- TRNA LIGASE) (METRS) - CANDIDA ALBICANS (YEAST).
O84035 METHIONYL-TRNA SYNTHETASE - CHLAMYDIA TRACHOMATIS.
SYMC_YEAST METHIONYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYMM_YEAST METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.10) (METHIONINE-- TRNA LIGASE) (METRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYM_ARCFU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - ARCHAEOGLOBUS FULGIDUS.
SYM_BACST METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BACILLUS STEAROTHERMOPHILUS.
SYM_BACSU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BACILLUS SUBTILIS.
SYM_BORBU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
SYM_CAEEL PROBABLE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - CAENORHABDITIS ELEGANS.
SYM_ECOLI METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - ESCHERICHIA COLI.
SYM_HAEIN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HAEMOPHILUS INFLUENZAE.
SYM_HELPY METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
SYM_HUMAN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - HOMO SAPIENS (HUMAN).
SYM_METJA METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - METHANOCOCCUS JANNASCHII.
SYM_METTH METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
SYM_MYCGE METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOPLASMA GENITALIUM.
SYM_MYCPN METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOPLASMA PNEUMONIAE.
SYM_MYCTU METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - MYCOBACTERIUM TUBERCULOSIS.
SYM_SYNY3 METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
SYM_THETH METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - THERMUS AQUATICUS (SUBSP. THERMOPHILUS).
SYM_TREPA METHIONYL-TRNA SYNTHETASE (EC 6.1.1.10) (METHIONINE--TRNA LIGASE) (METRS) - TREPONEMA PALLIDUM.

O75005 VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
Q12019 HYPOTHETICAL 559.3 KD PROTEIN - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYIM_YEAST ISOLEUCYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.5) (ISOLEUCINE-- TRNA LIGASE) (ILERS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - ESCHERICHIA COLI.
SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (EC 6.1.1.5) (ISOLEUCINE--TRNA LIGASE) (ILERS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
SYLM_SACDO LEUCYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (EC 6.1.1.4) (LEUCINE--TRNA LIGASE) (LEURS) - SACCHAROMYCES DOUGLASII (YEAST).
SYV_ARCFU VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - ARCHAEOGLOBUS FULGIDUS.
SYV_METJA VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - METHANOCOCCUS JANNASCHII.
SYV_METTH VALYL-TRNA SYNTHETASE (EC 6.1.1.9) (VALINE--TRNA LIGASE) (VALRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
YLJ6_CAEEL HYPOTHETICAL 272.0 KD PROTEIN C50C3.6 IN CHROMOSOME III - CAENORHABDITIS ELEGANS.
Scan History
OWL31_1    3  50   NSINGLE    
SPTR37_9f 2 120 NSINGLE
Initial Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
VTTPLYYVNDVPHL SYM_SYNY3 11 11 -
VTTPIYYVNAEPHL SYM_THETH 7 7 -
LTTPIYYPSDKLHI SYM_BACST 8 8 -
ITTPIYYVNDIPHI SYM_HELPY 6 6 -
ITTPIYYPSGKLHI SYM_BACSU 10 10 -
ITSALPYVNNVPHL SYM_HUMAN 268 268 -
ITTPIYYASGKPHI SYM_MYCGE 6 6 -
VTTPIFYPNAKPHL SYMM_YEAST 17 17 -
ITTALAYTNGPLHL SYM_METJA 5 5 -
VTCALPYANGAIHL SYM_HAEIN 10 10 -
VTCALPYANGSIHL SYM_ECOLI 9 9 -

Motif 2 width=15
Element Seqn Id St Int Rpt
QGYDVLMITGTDEHG SYM_SYNY3 43 18 -
DGYRTFFLTGTDEHG SYM_THETH 39 18 -
RGYDVMYLTGTDEHG SYM_BACST 40 18 -
QGEEVFFLTGTDEHG SYM_HELPY 38 18 -
KGFDVRYLTGTDEHG SYM_BACSU 42 18 -
RQWNTLYLCGTDEYG SYM_HUMAN 301 19 -
NGYEAFLLVGSDEHG SYM_MYCGE 38 18 -
KGNLSFFTTGTDEHG SYMM_YEAST 49 18 -
RGEDVIHVGGTDNHG SYM_METJA 38 19 -
RGNKIHFVCADDAHG SYM_HAEIN 42 18 -
RGHEVNFICADDAHG SYM_ECOLI 41 18 -

Motif 3 width=12
Element Seqn Id St Int Rpt
ILYDRFSRTTDP SYM_SYNY3 91 33 -
IAYDDFIRTTEE SYM_THETH 87 33 -
ISYDDFIRTTQE SYM_BACST 88 33 -
LDYDGFIRTTDS SYM_HELPY 86 33 -
ISNDDFIRTTEK SYM_BACSU 90 33 -
ISFDIFGRTTTP SYM_HUMAN 349 33 -
ISFDHFIRTTDE SYM_MYCGE 86 33 -
INYTRFIRTTDP SYMM_YEAST 98 34 -
VEFDAFGKTHSQ SYM_METJA 86 33 -
ISFDNYHSTHSE SYM_HAEIN 90 33 -
ISYDNYHSTHSE SYM_ECOLI 89 33 -

Motif 4 width=12
Element Seqn Id St Int Rpt
IYVWFDALLGYV SYM_SYNY3 228 125 -
TYVWFDALLNYV SYM_THETH 224 125 -
IYVWIDALANYI SYM_BACST 224 124 -
VYVWLDALLNYA SYM_HELPY 228 130 -
VYVWIDALFNYL SYM_BACSU 237 135 -
FYVWFDATIGYL SYM_HUMAN 515 154 -
IYVWFDALFSYI SYM_MYCGE 221 123 -
VYVWFDALCNYL SYMM_YEAST 244 134 -
MYVWLEAPIGYI SYM_METJA 244 146 -
FYVWLDAPIGYM SYM_HAEIN 251 149 -
FYVWLDAPIGYM SYM_ECOLI 250 149 -

Motif 5 width=16
Element Seqn Id St Int Rpt
HLIGKDILRFHAVYWP SYM_SYNY3 264 24 -
HLIGKDILKPHAVFWP SYM_THETH 255 19 -
HLVGKEIVRFHTIYWP SYM_BACST 257 21 -
HIVGKDILRFHAIYWP SYM_HELPY 260 20 -
HLVGKEIVRFHTIYWP SYM_BACSU 270 21 -
QFMAKDNVPFHSLVFP SYM_HUMAN 550 23 -
HLISREITRFHCIYWP SYM_MYCGE 259 26 -
HVIGKDIAKFHTVYWP SYMM_YEAST 300 44 -
HFIGKDITVHHAVFWP SYM_METJA 278 22 -
HFIGKDIVYFHSLFWP SYM_HAEIN 290 27 -
HFIGKDIVYFHSLFWP SYM_ECOLI 291 29 -

Motif 6 width=12
Element Seqn Id St Int Rpt
DLANDLGNLLNR SYM_SYNY3 356 76 -
DLADDLGNLVQR SYM_THETH 348 77 -
DLANDLGNLLHR SYM_BACST 349 76 -
NLNNDLGNLLNR SYM_HELPY 352 76 -
DLANDLGNLLNR SYM_BACSU 362 76 -
ELLNNLGNFINR SYM_HUMAN 645 79 -
DLANSFGNHVSR SYM_MYCGE 352 77 -
LLVSKWGNLINR SYMM_YEAST 391 75 -
ELINIIGNFTHR SYM_METJA 371 77 -
DIVNKLVNLASR SYM_HAEIN 383 77 -
DIVNKVVNLASR SYM_ECOLI 384 77 -
Final Motifs
Motif 1  width=14
Element Seqn Id St Int Rpt
VTTPLYYVNDVPHL SYM_SYNY3 11 11 -
LTTPLYYVNAPPHM O23761 73 73 -
VTTPIYYVNDVPHL O67298 9 9 -
ITTPIYYVNSEPHI O33925 5 5 -
VTTAIAYPNAAPHV SYM_MYCTU 6 6 -
VTTPIYYVNAEPHL SYM_THETH 7 7 -
LTTPIYYPSDKLHI SYM_BACST 8 8 -
ITTPIYYVNDIPHI SYM_HELPY 6 6 -
ITTPIYYPSGKLHI SYM_BACSU 10 10 -
VTSALPYANGPIHA O58721 6 6 -
ITTPIYYASGKPHI SYM_MYCPN 6 6 -
ITSALPYVNNVPHL O13634 21 21 -
ITCALPYANGPTHL SYM_METTH 6 6 -
ITSALPYVNNVPHL SYMC_YEAST 199 199 -
ITSALPYVNNVPHL SYM_HUMAN 268 268 -
ITAALPYVNNVPHL SYM_TREPA 6 6 -
ITAALPYVNNVPHL SYM_CAEEL 39 39 -
ITTPIYYASGKPHI SYM_MYCGE 6 6 -
VTAALPYVNNIPHL SYM_BORBU 7 7 -
VTTPIFYPNAKPHL SYMM_YEAST 17 17 -
LTTPIFYVNAAPHL O14000 23 23 -
ITSALPYANGPLHF O84035 8 8 -
ITTPIFYVNAAPHI O74634 22 22 -
ITTALAYTNGPLHL SYM_METJA 5 5 -
VTCGLPYANGKAHV SYM_ARCFU 4 4 -
VTCALPYANGAIHL SYM_HAEIN 10 10 -
VTCALPYANGSIHL SYM_ECOLI 9 9 -

Motif 2 width=15
Element Seqn Id St Int Rpt
QGYDVLMITGTDEHG SYM_SYNY3 43 18 -
LGKKVIFITGTDEHG O23761 105 18 -
RDYDVFFLTGTDEHG O67298 41 18 -
MGYDVFFLTGTDEHG O33925 37 18 -
DRYDVRFLTGTDEHG SYM_MYCTU 38 18 -
DGYRTFFLTGTDEHG SYM_THETH 39 18 -
RGYDVMYLTGTDEHG SYM_BACST 40 18 -
QGEEVFFLTGTDEHG SYM_HELPY 38 18 -
KGFDVRYLTGTDEHG SYM_BACSU 42 18 -
KGEDVVFICGTDEHG O58721 39 19 -
NGYEAYFLTGTDEHG SYM_MYCPN 38 18 -
RNHNTLYICGTDEYG O13634 54 19 -
RGDDVLFVCATDEHG SYM_METTH 39 19 -
RNYNALFICGTDEYG SYMC_YEAST 232 19 -
RQWNTLYLCGTDEYG SYM_HUMAN 301 19 -
RGYHTCFVCGTDEYG SYM_TREPA 38 18 -
RGHQTFYVGGTDEYG SYM_CAEEL 72 19 -
NGYEAFLLVGSDEHG SYM_MYCGE 38 18 -
SGIETLYVCGTDEYG SYM_BORBU 39 18 -
KGNLSFFTTGTDEHG SYMM_YEAST 49 18 -
PDVSVISSTGTDEHG O14000 56 19 -
QGKEVLYICGSDEYG O84035 41 19 -
PSKESFMLTGTDEHG O74634 55 19 -
RGEDVIHVGGTDNHG SYM_METJA 38 19 -
SGEEVVFVCGSDCHG SYM_ARCFU 36 18 -
RGNKIHFVCADDAHG SYM_HAEIN 42 18 -
RGHEVNFICADDAHG SYM_ECOLI 41 18 -

Motif 3 width=12
Element Seqn Id St Int Rpt
ILYDRFSRTTDP SYM_SYNY3 91 33 -
IAYDKFIRTTDP O23761 153 33 -
IEYTKFIRTTDP O67298 89 33 -
ITNDYFIRTTDE O33925 85 33 -
ISFDRFIRTTDA SYM_MYCTU 86 33 -
IAYDDFIRTTEE SYM_THETH 87 33 -
ISYDDFIRTTQE SYM_BACST 88 33 -
LDYDGFIRTTDS SYM_HELPY 86 33 -
ISNDDFIRTTEK SYM_BACSU 90 33 -
ISFDFFGRTELP O58721 87 33 -
INFDHFIRTTDL SYM_MYCPN 86 33 -
IDFDHFGRTTTP O13634 102 33 -
ISFDSFTRTTDE SYM_METTH 87 33 -
IGFDYFGRTTTD SYMC_YEAST 280 33 -
ISFDIFGRTTTP SYM_HUMAN 349 33 -
LSFDYFGRTTSD SYM_TREPA 86 33 -
IDFSHFGRTTTD SYM_CAEEL 120 33 -
ISFDHFIRTTDE SYM_MYCGE 86 33 -
IEFDIFGRTTNK SYM_BORBU 87 33 -
INYTRFIRTTDP SYMM_YEAST 98 34 -
TKFTHFIRTTNP O14000 104 33 -
ISVDFFSRTTNT O84035 89 33 -
VNYDRFIRTTDN O74634 103 33 -
VEFDAFGKTHSQ SYM_METJA 86 33 -
IKFDFYGRTDSD SYM_ARCFU 84 33 -
ISFDNYHSTHSE SYM_HAEIN 90 33 -
ISYDNYHSTHSE SYM_ECOLI 89 33 -

Motif 4 width=12
Element Seqn Id St Int Rpt
IYVWFDALLGYV SYM_SYNY3 228 125 -
IYVWFDALLGYI O23761 289 124 -
IYVWFDALFNYI O67298 227 126 -
IYVWVDALINYI O33925 224 127 -
MYVWVDALTNYL SYM_MYCTU 225 127 -
TYVWFDALLNYV SYM_THETH 224 125 -
IYVWIDALANYI SYM_BACST 224 124 -
VYVWLDALLNYA SYM_HELPY 228 130 -
VYVWIDALFNYL SYM_BACSU 237 135 -
LYVWFEAPIGYI O58721 251 152 -
IYVWFDALFNYI SYM_MYCPN 221 123 -
LYVWFDATIGYI O13634 268 154 -
IYVWGEAFLGYI SYM_METTH 249 150 -
LYVWFDATIGYV SYMC_YEAST 446 154 -
FYVWFDATIGYL SYM_HUMAN 515 154 -
FYVWFDAPVGYI SYM_TREPA 250 152 -
FYVWFDAPIGYL SYM_CAEEL 288 156 -
IYVWFDALFSYI SYM_MYCGE 221 123 -
FYVWFDAPIGYI SYM_BORBU 252 153 -
VYVWFDALCNYL SYMM_YEAST 244 134 -
IYVWLDALINYI O14000 251 135 -
FYVWFDAPIGYI O84035 248 147 -
IYVWFDALLNYL O74634 249 134 -
MYVWLEAPIGYI SYM_METJA 244 146 -
VYVWVDAPIGYI SYM_ARCFU 243 147 -
FYVWLDAPIGYM SYM_HAEIN 251 149 -
FYVWLDAPIGYM SYM_ECOLI 250 149 -

Motif 5 width=16
Element Seqn Id St Int Rpt
HLIGKDILRFHAVYWP SYM_SYNY3 264 24 -
HLIGKDILRFHAVYWP O23761 325 24 -
HLVGKDILRFHTVYWP O67298 254 15 -
HLIGKEINRFHSIIWP O33925 256 20 -
HMIGKDIIRFHAVYWP SYM_MYCTU 258 21 -
HLIGKDILKPHAVFWP SYM_THETH 255 19 -
HLVGKEIVRFHTIYWP SYM_BACST 257 21 -
HIVGKDILRFHAIYWP SYM_HELPY 260 20 -
HLVGKEIVRFHTIYWP SYM_BACSU 270 21 -
HFIGKDNIPFHAIFWP O58721 293 30 -
HLISREITRFHCIYWP SYM_MYCPN 259 26 -
QFMGKDNVPFHTVIFP O13634 303 23 -
HFIGKDIIYHHAIFWP SYM_METTH 284 23 -
QFMGKDNVPFHTVVFP SYMC_YEAST 481 23 -
QFMAKDNVPFHSLVFP SYM_HUMAN 550 23 -
QFVGKDNIPFHTLFFP SYM_TREPA 301 39 -
NFVGKDNVAFHAVMFP SYM_CAEEL 324 24 -
HLISREITRFHCIYWP SYM_MYCGE 259 26 -
QFIGKDNILFHTIIFP SYM_BORBU 287 23 -
HVIGKDIAKFHTVYWP SYMM_YEAST 300 44 -
HVIGKDIIRFHCIYWP O14000 285 22 -
QFIGKDNTSFHAAIFP O84035 288 28 -
HVIGKDIIRFHCIYWP O74634 288 27 -
HFIGKDITVHHAVFWP SYM_METJA 278 22 -
HFIGLDIVYHHCIFWP SYM_ARCFU 281 26 -
HFIGKDIVYFHSLFWP SYM_HAEIN 290 27 -
HFIGKDIVYFHSLFWP SYM_ECOLI 291 29 -

Motif 6 width=12
Element Seqn Id St Int Rpt
DLANDLGNLLNR SYM_SYNY3 356 76 -
HLANTIGNLLNR O23761 417 76 -
ELANEIGNLYSR O67298 346 76 -
DLANDYGNLLHR O33925 348 76 -
DLANELGNLAQR SYM_MYCTU 350 76 -
DLADDLGNLVQR SYM_THETH 348 77 -
DLANDLGNLLHR SYM_BACST 349 76 -
NLNNDLGNLLNR SYM_HELPY 352 76 -
DLANDLGNLLNR SYM_BACSU 362 76 -
ELVNNLGNFVHR O58721 395 86 -
DLANSFGNHASR SYM_MYCPN 352 77 -
ELLANLGNFVNR O13634 398 79 -
ELADVLGNFLHR SYM_METTH 376 76 -
ELLANLGNFVNR SYMC_YEAST 576 79 -
ELLNNLGNFINR SYM_HUMAN 645 79 -
ELIGNLCNLVNR SYM_TREPA 396 79 -
ELLNNLGNFINR SYM_CAEEL 419 79 -
DLANSFGNHVSR SYM_MYCGE 352 77 -
ELIDNFSNLVNR SYM_BORBU 382 79 -
LLVSKWGNLINR SYMM_YEAST 391 75 -
DLRRSLGVLLSR O14000 377 76 -
ELVGKYGNFVNR O84035 382 78 -
AVLGKYCNLISR O74634 379 75 -
ELINIIGNFTHR SYM_METJA 371 77 -
EVIATLGNFLYR SYM_ARCFU 375 78 -
DIVNKLVNLASR SYM_HAEIN 383 77 -
DIVNKVVNLASR SYM_ECOLI 384 77 -