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PR01039

Identifier
TRNASYNTHTRP  [View Relations]  [View Alignment]  
Accession
PR01039
No. of Motifs
4
Creation Date
18-DEC-1998  (UPDATE 16-JUN-1999)
Title
Tryptophanyl-tRNA synthetase signature
Database References
PRINTS; PR90000 TRNASYNTH; PR90001 TRNASYNTHCLI
PROSITE; PS00178 AA_TRNA_LIGASE_I
PFAM; PF00579 tRNA-synt_1b
INTERPRO; IPR002306
Literature References
1. LODISH, H., BALTIMORE, D., BERK, A., ZIPURSKY, S.L., MATSUDAIRA, P.
AND DARNELL, J.
Nucleic Acids, the Genetic Code, and Protein Synthesis. 
IN MOLECULAR CELL BIOLOGY, SCIENTIFIC AMERICAN BOOKS (NEW YORK), 1995,
PP.126-128
 
2. DELARUE, M.
Aminoacyl-tRNA synthetases.
CURR.OPIN.STRUCT.BIOL. 5 48-55 (1995).
 
3. PERONA, J.J., ROULD, M. AND STEITZ, T.A.
Structural Basis for Transfer RNA Aminoacylation by Escherichia coli
Glutaminyl-tRNA Synthetase.
BIOCHEMISTRY 32 8758-8771 (1993).

Documentation
Appropriate attachment of an amino acid to its cognate tRNA is the key to
faithful translation of the genetic code. The family of enzymes responsible
for this is the aminoacyl-tRNA synthetases (AATRSs) (EC 6.1.1.-).
 
AATRSs catalyse a two-step reaction:
 
(1) Enzyme + amino acid + ATP ---> Enzyme(aminoacyl-AMP) + PPi
 
(2) tRNA + Enzyme(aminoacyl-AMP) ---> aminoacyl-tRNA + AMP + Enzyme
 
In the first step, they form an aminoacyl-adenylate, in which the carboxyl
of the amino acid is linked to the alpha-phosphate of ATP, by displacing
the pyrophosphate. When the correct tRNA is bound, the aminoacyl group is
transferred to the 2'- or 3'-terminal OH of the tRNA at the expense of AMP
[1].
 
Based on structural and sequence comparisons, this group of at least 20
proteins (in prokaryotes there are approximately 20, but in eukaryotes
there are usually 2 forms for each amino acid; namely, the cytosolic and
mitochondrial forms) can be divided into two classes.
 
Class I AATRSs contain a characteristic Rossman fold and are mostly
monomeric. At the primary structure level, two highly-conserved motifs
are observed, `HIGH' and `KMSKS' [2,3]; these are associated with the ATP-
binding site.
 
Class II AATRSs share an anti-parallel beta-sheet formation, flanked by
alpha-helices [3], and are mostly dimeric or multimeric.
 
Further distinction between the two classes is evident when the reaction
mechanisms are investigated. In reactions catalysed by the class I AATRSs,
the aminoacyl group is coupled to the 2'-hydroxyl of the tRNA, while, in
class II reactions, the 3'-hydroxyl site is preferred.
 
Tryptophanyl-tRNA synthetase (EC 6.1.1.2 ) is specific to tryptophan and 
belongs to class I.
 
TRNASYNTHTRP is a 4-element fingerprint that provides a signature for the
tryptophanyl-tRNA synthetase. The fingerprint was derived from an initial
alignment of 23 sequences: the motifs were drawn from conserved regions 
within the N-terminal portion of the alignment - motifs 1 and 4 contain the
characteristic HIGH and KMSKS regions respectively. Two iterations on
OWL31.1 were required to reach convergence, at which point a true set
comprising 33 sequences was identified. Several partial matches were also
found, all of which are tyrosyl-tRNA synthetases.
 
An update on SPTR37_9f identified a true set of 29 sequences, and 4
partial matches all of which are tyrosyl-tRNA synthetases.
Summary Information
  29 codes involving  4 elements
0 codes involving 3 elements
4 codes involving 2 elements
Composite Feature Index
429292929
30000
23014
1234
True Positives
O42875        O53386        O59584        O67115        
O82313 O84589 SYWC_YEAST SYWM_CAEEL
SYWM_YEAST SYW_ARCFU SYW_BACST SYW_BACSU
SYW_BORBU SYW_BOVIN SYW_CLOLO SYW_ECOLI
SYW_HAEIN SYW_HELPY SYW_HUMAN SYW_METJA
SYW_METTH SYW_MOUSE SYW_MYCGE SYW_MYCLE
SYW_MYCPN SYW_RABIT SYW_SCHPO SYW_SYNY3
SYW_TREPA
True Positive Partials
Codes involving 2 elements
SYY_ARCFU SYY_METTH SYY_SULSO SYY_SYNY3
Sequence Titles
O42875      PROBABLE TRYPTOPHANYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST). 
O53386 TRYPTOPHANYL TRNA SYNTHETASE - MYCOBACTERIUM TUBERCULOSIS.
O59584 301AA LONG HYPOTHETICAL TRYPTOPHANYL-TRNA SYNTHETASE - PYROCOCCUS HORIKOSHII.
O67115 TRYPTOPHANYL-TRNA SYNTHETASE - AQUIFEX AEOLICUS.
O82313 PUTATIVE TRYTOPHANYL-TRNA SYNTHETASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O84589 TRYPTOPHANYL TRNA SYNTHETASE - CHLAMYDIA TRACHOMATIS.
SYWC_YEAST TRYPTOPHANYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.2) (TRYPTOPHAN-- TRNA LIGASE) (TRPRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYWM_CAEEL PROBABLE TRYPTOPHANYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - CAENORHABDITIS ELEGANS.
SYWM_YEAST TRYPTOPHANYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC 6.1.1.2) (TRYPTOPHAN-- TRNA LIGASE) (TRPRS) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
SYW_ARCFU TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - ARCHAEOGLOBUS FULGIDUS.
SYW_BACST TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - BACILLUS STEAROTHERMOPHILUS.
SYW_BACSU TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - BACILLUS SUBTILIS.
SYW_BORBU TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
SYW_BOVIN TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - BOS TAURUS (BOVINE).
SYW_CLOLO TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - CLOSTRIDIUM LONGISPORUM.
SYW_ECOLI TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - ESCHERICHIA COLI.
SYW_HAEIN TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - HAEMOPHILUS INFLUENZAE.
SYW_HELPY TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
SYW_HUMAN TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) (IFP53) - HOMO SAPIENS (HUMAN).
SYW_METJA TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - METHANOCOCCUS JANNASCHII.
SYW_METTH TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
SYW_MOUSE TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - MUS MUSCULUS (MOUSE).
SYW_MYCGE TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - MYCOPLASMA GENITALIUM.
SYW_MYCLE TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - MYCOBACTERIUM LEPRAE.
SYW_MYCPN TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - MYCOPLASMA PNEUMONIAE.
SYW_RABIT TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - ORYCTOLAGUS CUNICULUS (RABBIT).
SYW_SCHPO PUTATIVE TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
SYW_SYNY3 TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
SYW_TREPA TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) (TRYPTOPHAN--TRNA LIGASE) (TRPRS) - TREPONEMA PALLIDUM.

SYY_ARCFU TYROSYL-TRNA SYNTHETASE (EC 6.1.1.1) (TYROSINE--TRNA LIGASE) (TYRRS) - ARCHAEOGLOBUS FULGIDUS.
SYY_METTH TYROSYL-TRNA SYNTHETASE (EC 6.1.1.1) (TYROSINE--TRNA LIGASE) (TYRRS) - METHANOBACTERIUM THERMOAUTOTROPHICUM.
SYY_SULSO TYROSYL-TRNA SYNTHETASE (EC 6.1.1.1) (TYROSINE--TRNA LIGASE) (TYRRS) - SULFOLOBUS SOLFATARICUS.
SYY_SYNY3 TYROSYL-TRNA SYNTHETASE (EC 6.1.1.1) (TYROSINE--TRNA LIGASE) (TYRRS) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
Scan History
OWL31_1    2  100  NSINGLE    
SPTR37_9f 3 100 NSINGLE
Initial Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
ITIGNYIGALRQFVELQ SYW_BACST 14 14 -
LHLGNALGAITQWVALQ SYW_MYCLE 21 21 -
IHLGNYLGAIKHWVEMQ SYW_HELPY 29 29 -
FHLGNYLGATRVWTDLC SYWM_YEAST 47 47 -
LHIGHYVGSLKNRVQLQ SYW_CLOLO 16 16 -
MHVGHLIPFIFTKWLQD SYW_HUMAN 169 169 -
CNVGHLIPFIFTKWLQD RABERFX 173 173 -
MHVGHLIPFIFTKWLQD AB012222 3 3 -
MHIGHIIPFFATKWLQE G71206 1 1 -
LTIGNYMGALRQWVKMQ ECDAMOPRA6 16 16 -
LHLGHYVGSVVNRLKFQ E70100 18 18 -
PHFGHKMTMDEIVWHQS SYW_ARCFU 76 76 -
MHIGHKMIVDQLRWYDR SYW_METTH 74 74 -
MHLGHMIPFVFTKWLQE SYWC_YEAST 116 116 -
MHFGHKMVVDLLKFYQK SYW_METJA 79 79 -
PHLGNFFGSIEPWTELQ SYWM_CAEEL 33 33 -
MHVGHLIPFIFTKWLQD SYW_BOVIN 174 174 -
MHLGHMIPFMFCKWLQD SYW_SCHPO 96 96 -
QHLGNFLGVMQGLKQLQ SYW_MYCGE 15 15 -
MHVGHLIPFIFTKWLQD SYW_RABIT 173 173 -
VTLGNYIGAMKQFVELQ SYW_BACSU 15 15 -
LTIGNYMGALRQWVNMQ SYW_ECOLI 16 16 -
LHLGNYLGAIRSWVEQQ SYW_SYNY3 56 56 -

Motif 2 width=20
Element Seqn Id St Int Rpt
DIIACGFDINKTFIFSDLDY SYW_HUMAN 221 35 -
DYLACGINPDKVSIYLQSAI E70100 71 36 -
LYLACGIDPEKSTIFVQSHV ECDAMOPRA6 66 33 -
DIMPCGFDVNKTFIFSDLDY RABERFX 225 35 -
DIIACGFDINKTFIFSDLEY AB012222 55 35 -
DIIAVGFDPDKTFIFQNSEF G71206 54 36 -
LYLAVGLDPEKATLFIQSEV SYW_BACSU 65 33 -
LYLACGIDPEKSTIFVQSHV SYW_ECOLI 66 33 -
LYLACGIDLQYSTIFVQSHV SYW_SYNY3 106 33 -
KYLAVGIDPTQATLFIQSEV SYW_BACST 64 33 -
QYLALGIDPGRAVVFVQSHV SYW_MYCLE 75 37 -
LLLACGIDPKQSGLFIQSEV SYW_HELPY 79 33 -
SILAVGVDPEKASVIYQSAI SYWM_YEAST 102 38 -
DYLAVGIDPLKSTILVQSQI SYW_CLOLO 69 36 -
DIIACGFDVNKTFIFSDLDY SYW_RABIT 225 35 -
TLLALGLDYGKVNLFLQSDL SYW_MYCGE 65 33 -
DIIAVGFDPKKTFIFMNSTY SYW_SCHPO 149 36 -
KDITCGFDINKTFIFSDLDY SYW_BOVIN 225 34 -
SLIACGVDPNRTLLFRQSDV SYWM_CAEEL 88 38 -
NYIALGLDPEKINVYLQSKY SYW_METJA 131 35 -
DIIAVGFDPKNTFIFSDLQY SYWC_YEAST 169 36 -
GYIALGLDLEKDNIHVYLQS SYW_METTH 126 35 -
SIIALGLREDAVIYFQSKSS SYW_ARCFU 127 34 -

Motif 3 width=22
Element Seqn Id St Int Rpt
NLVPVGRDNESHIEFARELARR E70100 148 57 -
DLVPVGEDQKQHLELTRNLAER SYW_BACSU 140 55 -
NLVPVGEDQKQHLELSRDIAQR SYW_ECOLI 142 56 -
DKVPVGEDQKQHLELTRDIVIR SYW_SYNY3 182 56 -
DIVPVGEDQKQHIELTRDLAER SYW_BACST 139 55 -
DLVPVGEDQRQHLELARDLAQR SYW_MYCLE 152 57 -
DLVPVGEDQKQHLELTRNIAEK SYW_HELPY 155 56 -
THVPVGDDQSQHLELTRHLAEK SYWM_YEAST 191 69 -
TTVPVGEDQLPMIEQAREIVRS SYW_CLOLO 147 58 -
CLIPCAIDQDPYFRMTRDVAPR SYW_HUMAN 305 64 -
CLIPCAIDQDPYFRMTRDVAPR SYW_RABIT 309 64 -
DIVPVGNDQKQHLELTNDLAKR SYW_MYCGE 147 62 -
CLIPCAIDQDPYFRLTRDVSGR SYW_SCHPO 231 62 -
CLIPCAIDQDPYFRMTRDVAPR SYW_BOVIN 309 64 -
TTVPVGEDQSQHLNLLGGLAYA SYWM_CAEEL 165 57 -
VVVPVGIDQDPHIRLTRDIANR SYW_METJA 210 59 -
CLIPCAIDQDPYFRVCRDVADK SYWC_YEAST 251 62 -
VIVPVGPDQDPHIRLTRDIAAR SYW_METTH 205 59 -
VVVPVGADQDPHMRLTRDLAAR SYW_ARCFU 203 56 -
CLIPAAIDQDPYWRLQRDFAES G71206 124 50 -
CLIPCAIDQDPYFRMTRDVAPR AB012222 139 64 -
CLIPCAIDQDPYFRMTRDVAPR RABERFX 309 64 -
NLVPVGEDQKQHLELSRDIAQR ECDAMOPRA6 142 56 -

Motif 4 width=11
Element Seqn Id St Int Rpt
KMSASDPNSSI SYW_HUMAN 349 22 -
KMSASDPNSSI SYW_RABIT 353 22 -
KMSKSNPDQNG SYW_MYCGE 200 31 -
KMSASKDSSAI SYW_SCHPO 275 22 -
KMSASDPNSSI SYW_BOVIN 353 22 -
KMSKSSGGPRS SYWM_CAEEL 219 32 -
KMSSSKPETAI SYW_METJA 255 23 -
KMSASDDTTAI SYWC_YEAST 295 22 -
KMSSNRPKSAI SYW_METTH 251 24 -
KMSSSKPESYI SYW_ARCFU 308 83 -
KMSKSDDNRNN SYW_ECOLI 195 31 -
KMSKSDESELS SYW_SYNY3 239 35 -
KMSKSDPNPKA SYW_BACST 192 31 -
KMSKSASSDAG SYW_MYCLE 205 31 -
KMSKSDPNQKA SYW_BACSU 193 31 -
KMSASKPETAI G71206 168 22 -
KMSASDPNSSI AB012222 183 22 -
KMSASDPNSSI RABERFX 353 22 -
KMSKSDDNRNN ECDAMOPRA6 195 31 -
KMSKSLDNAIF E70100 200 30 -
KMSKSHQGANH SYW_HELPY 208 31 -
KMSKSDPNHDS SYWM_YEAST 244 31 -
KMSKSIGNAIY SYW_CLOLO 201 32 -
Final Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
VTLGNYIGAMKQFVELQ SYW_BACSU 15 15 -
LTIGNYMGALRQWVNMQ SYW_ECOLI 16 16 -
LTIGNYLGALRNWVKMQ SYW_HAEIN 16 16 -
LHLGNYLGAIRSWVEQQ SYW_SYNY3 56 56 -
VHLGNYLGAIKNWVALQ O82313 15 15 -
LHLGNALGAVAQWVGLQ O53386 21 21 -
ITIGNYIGALRQFVELQ SYW_BACST 14 14 -
LHLGNALGAITQWVALQ SYW_MYCLE 21 21 -
LHLGHYFGVIRNWVKLQ O67115 13 13 -
QHLGNYLGVMQSLIELQ SYW_MYCPN 15 15 -
IHLGNYLGAIKHWVEMQ SYW_HELPY 29 29 -
PHIGNYLGSLKQWVQLQ O42875 26 26 -
FHLGNYLGATRVWTDLC SYWM_YEAST 47 47 -
LHLGHYAGSLGTRLRIQ SYW_TREPA 14 14 -
LHIGHYVGSLKNRVQLQ SYW_CLOLO 16 16 -
LHLGHWIGSIMNRLQLQ O84589 16 16 -
MHVGHLIPFIFTKWLQD SYW_HUMAN 169 169 -
MHVGHLIPFIFTKWLQD SYW_RABIT 173 173 -
MHLGHLVPFIFTKWLED SYW_MOUSE 173 173 -
QHLGNFLGVMQGLKQLQ SYW_MYCGE 15 15 -
LHLGHYVGSVVNRLKFQ SYW_BORBU 18 18 -
MHLGHMIPFMFCKWLQD SYW_SCHPO 96 96 -
MHVGHLIPFIFTKWLQD SYW_BOVIN 174 174 -
PHLGNFFGSIEPWTELQ SYWM_CAEEL 33 33 -
MHFGHKMVVDLLKFYQK SYW_METJA 79 79 -
MHIGHIIPFFATKWLQE O59584 1 1 -
MHLGHMIPFVFTKWLQE SYWC_YEAST 116 116 -
MHIGHKMIVDQLRWYDR SYW_METTH 74 74 -
PHFGHKMTMDEIVWHQS SYW_ARCFU 76 76 -

Motif 2 width=20
Element Seqn Id St Int Rpt
LYLAVGLDPEKATLFIQSEV SYW_BACSU 65 33 -
LYLACGIDPEKSTIFVQSHV SYW_ECOLI 66 33 -
LYLACGIDPNKSTIFVQSHV SYW_HAEIN 66 33 -
LYLACGIDLQYSTIFVQSHV SYW_SYNY3 106 33 -
LYLACGIDVSKASVFVQSHV O82313 65 33 -
QYLALGIDPGRATIFVQSQV O53386 71 33 -
KYLAVGIDPTQATLFIQSEV SYW_BACST 64 33 -
QYLALGIDPGRAVVFVQSHV SYW_MYCLE 75 37 -
DWLALGLDPQKSVLFIQSLV O67115 64 34 -
TLLAVGLDPQKACLFLQSDL SYW_MYCPN 65 33 -
LLLACGIDPKQSGLFIQSEV SYW_HELPY 79 33 -
ALLAIGINPQKSTLFFQSDV O42875 82 39 -
SILAVGVDPEKASVIYQSAI SYWM_YEAST 102 38 -
DYLACGIDAQRAVIYLQSAV SYW_TREPA 67 36 -
DYLAVGIDPLKSTILVQSQI SYW_CLOLO 69 36 -
DWLSVGIDPEKSAIYLQSAI O84589 71 38 -
DIIACGFDINKTFIFSDLDY SYW_HUMAN 221 35 -
DIIACGFDVNKTFIFSDLDY SYW_RABIT 225 35 -
DIIACGFDINKTFIFSDLEY SYW_MOUSE 225 35 -
TLLALGLDYGKVNLFLQSDL SYW_MYCGE 65 33 -
DYLACGINPDKVSIYLQSAI SYW_BORBU 71 36 -
DIIAVGFDPKKTFIFMNSTY SYW_SCHPO 149 36 -
KDITCGFDINKTFIFSDLDY SYW_BOVIN 225 34 -
SLIACGVDPNRTLLFRQSDV SYWM_CAEEL 88 38 -
NYIALGLDPEKINVYLQSKY SYW_METJA 131 35 -
DIIAVGFDPDKTFIFQNSEF O59584 54 36 -
DIIAVGFDPKNTFIFSDLQY SYWC_YEAST 169 36 -
GYIALGLDLEKDNIHVYLQS SYW_METTH 126 35 -
SIIALGLREDAVIYFQSKSS SYW_ARCFU 127 34 -

Motif 3 width=22
Element Seqn Id St Int Rpt
DLVPVGEDQKQHLELTRNLAER SYW_BACSU 140 55 -
NLVPVGEDQKQHLELSRDIAQR SYW_ECOLI 142 56 -
KSVPVGDDQKQHLEITRDIANR SYW_HAEIN 142 56 -
DKVPVGEDQKQHLELTRDIVIR SYW_SYNY3 182 56 -
DFVPVGEDQKQHIELAREIAQR O82313 142 57 -
ELVPVGEDQRQHLELARDVAQR O53386 148 57 -
DIVPVGEDQKQHIELTRDLAER SYW_BACST 139 55 -
DLVPVGEDQRQHLELARDLAQR SYW_MYCLE 152 57 -
EGVPVGEDQLPHIELSREIARR O67115 211 127 -
DIVPVGNDQKQHLELTRDLAQR SYW_MYCPN 147 62 -
DLVPVGEDQKQHLELTRNIAEK SYW_HELPY 155 56 -
THIPVGKDQSQHVELTRSIARS O42875 172 70 -
THVPVGDDQSQHLELTRHLAEK SYWM_YEAST 191 69 -
HLVPVGKDNESHVELTREVAKR SYW_TREPA 144 57 -
TTVPVGEDQLPMIEQAREIVRS SYW_CLOLO 147 58 -
HLVPVGKDNEAHVELTRDIAKT O84589 150 59 -
CLIPCAIDQDPYFRMTRDVAPR SYW_HUMAN 305 64 -
CLIPCAIDQDPYFRMTRDVAPR SYW_RABIT 309 64 -
CLIPCAIDQDPYFRMTRDVAPR SYW_MOUSE 309 64 -
DIVPVGNDQKQHLELTNDLAKR SYW_MYCGE 147 62 -
NLVPVGRDNESHIEFARELARR SYW_BORBU 148 57 -
CLIPCAIDQDPYFRLTRDVSGR SYW_SCHPO 231 62 -
CLIPCAIDQDPYFRMTRDVAPR SYW_BOVIN 309 64 -
TTVPVGEDQSQHLNLLGGLAYA SYWM_CAEEL 165 57 -
VVVPVGIDQDPHIRLTRDIANR SYW_METJA 210 59 -
CLIPAAIDQDPYWRLQRDFAES O59584 124 50 -
CLIPCAIDQDPYFRVCRDVADK SYWC_YEAST 251 62 -
VIVPVGPDQDPHIRLTRDIAAR SYW_METTH 205 59 -
VVVPVGADQDPHMRLTRDLAAR SYW_ARCFU 203 56 -

Motif 4 width=11
Element Seqn Id St Int Rpt
KMSKSDPNQKA SYW_BACSU 193 31 -
KMSKSDDNRNN SYW_ECOLI 195 31 -
KMSKSDDNRNN SYW_HAEIN 195 31 -
KMSKSDESELS SYW_SYNY3 239 35 -
KMSKSAPSDQS O82313 208 44 -
KMSKSAGTDAG O53386 201 31 -
KMSKSDPNPKA SYW_BACST 192 31 -
KMSKSASSDAG SYW_MYCLE 205 31 -
KMSKSYGNAVF O67115 261 28 -
KMSKSSKNQNG SYW_MYCPN 200 31 -
KMSKSHQGANH SYW_HELPY 208 31 -
KMSKSDINSKN O42875 225 31 -
KMSKSDPNHDS SYWM_YEAST 244 31 -
KMSKSLGNAIF SYW_TREPA 195 29 -
KMSKSIGNAIY SYW_CLOLO 201 32 -
KMSKSANNAIY O84589 201 29 -
KMSASDPNSSI SYW_HUMAN 349 22 -
KMSASDPNSSI SYW_RABIT 353 22 -
KMSASDPNSSI SYW_MOUSE 353 22 -
KMSKSNPDQNG SYW_MYCGE 200 31 -
KMSKSLDNAIF SYW_BORBU 200 30 -
KMSASKDSSAI SYW_SCHPO 275 22 -
KMSASDPNSSI SYW_BOVIN 353 22 -
KMSKSSGGPRS SYWM_CAEEL 219 32 -
KMSSSKPETAI SYW_METJA 255 23 -
KMSASKPETAI O59584 168 22 -
KMSASDDTTAI SYWC_YEAST 295 22 -
KMSSNRPKSAI SYW_METTH 251 24 -
KMSSSKPESYI SYW_ARCFU 308 83 -