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PR00992

Identifier
ALARACEMASE  [View Relations]  [View Alignment]  
Accession
PR00992
No. of Motifs
9
Creation Date
28-NOV-1998  (UPDATE 06-JUN-1999)
Title
Alanine racemase signature
Database References

PROSITE; PS00395 ALANINE_RACEMASE
PFAM; PF00842 Ala_racemase
INTERPRO; IPR000821
PDB; 1SFT
SCOP; 1SFT
CATH; 1SFT
Literature References
1. HAYASHI, H., WADA, H., YOSHIMURA, T., ESAKI, N. AND SODA, K.
Recent topics in pyridoxal 5'-phosphate enzyme studies.
ANNU.REV.BIOCHEMISTRY 59 87-110 (1990).
 
2. SHAW, J.P., PETSKO, G.A. AND RINGE, D.
Determination of the structure of alanine racemase from Bacillus
stearothermophilus at 1.9-A resolution.
BIOCHEMISTRY 36 1329-1342 (1997).

Documentation
Alanine racemase catalyses the pyridoxal-dependent conversion of L-alanine
into D-alanine, a key component of bacterial peptidoglycan [1]. In E.coli
and S.typhimurium, there are two alanine racemase isoforms: alr is a
biosynthetic form required for cell wall formation; and dadB functions in
L-alanine catabolism. By contrast with dadB and alr, both of which are
monomeric enzymes, the alanine racemase of Bacillaceae are homodimers. In 
P.putida, a broad-specificity amino acid racemase is structurally and
functionally related to alanine racemase.
 
The 3D-structure of the dimeric alanine racemase from B.stearothermophilus 
has been determined to a resolution of 1.9A [2]. Each monomer comprises
two domains, with an eight-stranded alpha/beta barrel at the N-terminus, and
a C-terminal beta-strand domain [2]. In the dimer, the mouth of the alpha/
beta barrel of one monomer faces the second domain of the other monomer. 
The pyridoxal 5'-phosphate (PLP) cofactor lies in and above the barrel mouth
and is covalently linked via an aldimine linkage to Lys39 [2]. 
 
Several other residues are involved in anchoring the PLP: for example, 
Arg219 forms a hydrogen bond with the pyridine nitrogen of the cofactor, 
which is assumed to influence electron delocalisation in PLP-alanine
intermediates; Arg136 donates a hydrogen bond to the phenolic oxygen of PLP,
and may be involved in substrate binding and stabilisation of intermediates;
and Tyr265' is postulated to be a 2 proton donor to the carbanion 
intermediate [2]. 
 
ALARACEMASE is a 9-element fingerprint that provides a signature for alanine
racemase. The fingerprint was derived from an initial alignment of 10 
sequences: the motifs were drawn from conserved regions spanning virtually
the full alignment length - motif 1 spans strand 2 and helix 2, and includes
the region encoded by PROSITE pattern ALANINE_RACEMASE (PS00395), which 
contains the pyridoxal-P attachment site; motif 2 includes helix 4 and 
strand 4; motifs 3 and 4 encode the C-termini of strands 6 and 7 res., motif
3 including the conserved Arg136; motif 5 spans helices 10-12 and strand 9,
and includes Arg219; motif 6 spans strands 12-13 and helix 14, and includes
Tyr265; motif 7 encodes the C-terminal portion of strand 14, helix 15 and
the N-terminus of helix 16; motif 8 spans strands 15 and 16; and motif 9
encodes helix 18. Three iterations on OWL30.2 were required to reach 
convergence, at which point a true set comprising 19 sequences was 
identified. Several partial matches were also found, all of which are 
homologues or fragments that fail to match three or more motifs.
 
An update on SPTR37_9f identified a true set of 18 sequences, and 3
partial matches.
Summary Information
  18 codes involving  9 elements
1 codes involving 8 elements
0 codes involving 7 elements
2 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
9181818181818181818
8101111111
7000000000
6212011221
5000000000
4000000000
3000000000
2000000000
123456789
True Positives
ALR1_ECOLI    ALR1_SALTY    ALR2_BACSU    ALR2_ECOLI    
ALR2_KLEAE ALR2_SALTY ALR_BACST ALR_BACSU
ALR_HAEIN ALR_HELPY ALR_LACPL ALR_MYCLE
ALR_MYCSM ALR_MYCTU ALR_SYNY3 O59828
O85045 O87498
True Positive Partials
Codes involving 8 elements
O86786
Codes involving 6 elements
ALR_AQUAE O51182
Sequence Titles
ALR1_ECOLI  ALANINE RACEMASE, BIOSYNTHETIC (EC 5.1.1.1) - ESCHERICHIA COLI. 
ALR1_SALTY ALANINE RACEMASE, BIOSYNTHETIC (EC 5.1.1.1) - SALMONELLA TYPHIMURIUM.
ALR2_BACSU PUTATIVE ALANINE RACEMASE (EC 5.1.1.1) - BACILLUS SUBTILIS.
ALR2_ECOLI ALANINE RACEMASE, CATABOLIC (EC 5.1.1.1) - ESCHERICHIA COLI.
ALR2_KLEAE ALANINE RACEMASE, CATABOLIC (EC 5.1.1.1) - KLEBSIELLA AEROGENES.
ALR2_SALTY ALANINE RACEMASE, CATABOLIC (EC 5.1.1.1) - SALMONELLA TYPHIMURIUM.
ALR_BACST ALANINE RACEMASE (EC 5.1.1.1) - BACILLUS STEAROTHERMOPHILUS.
ALR_BACSU ALANINE RACEMASE (EC 5.1.1.1) - BACILLUS SUBTILIS.
ALR_HAEIN ALANINE RACEMASE (EC 5.1.1.1) - HAEMOPHILUS INFLUENZAE.
ALR_HELPY ALANINE RACEMASE (EC 5.1.1.1) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
ALR_LACPL ALANINE RACEMASE (EC 5.1.1.1) - LACTOBACILLUS PLANTARUM.
ALR_MYCLE ALANINE RACEMASE (EC 5.1.1.1) - MYCOBACTERIUM LEPRAE.
ALR_MYCSM ALANINE RACEMASE (EC 5.1.1.1) - MYCOBACTERIUM SMEGMATIS.
ALR_MYCTU ALANINE RACEMASE (EC 5.1.1.1) - MYCOBACTERIUM TUBERCULOSIS.
ALR_SYNY3 ALANINE RACEMASE (EC 5.1.1.1) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
O59828 PUTATIVE ALANINE RACEMASE - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O85045 ALANINE RACEMASE (EC 5.1.1.1) - LISTERIA MONOCYTOGENES.
O87498 ALANINE RACEMASE (EC 5.1.1.1) - ESCHERICHIA COLI.

O86786 ALANINE RACEMASE (EC 5.1.1.1) - STREPTOMYCES COELICOLOR.

ALR_AQUAE ALANINE RACEMASE (EC 5.1.1.1) - AQUIFEX AEOLICUS.
O51182 ALANINE RACEMASE (ALR) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
Scan History
OWL30_2    3  100  NSINGLE    
SPTR37_9f 2 67 NSINGLE
Initial Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
HARVWSVVKANAYGHGI ALR2_ECOLI 27 27 -
ASKLVAVVKANAYGHGL ALR1_SALTY 26 26 -
DTHIMAVVKANAYGHGD ALR_BACST 31 31 -
ASKMVAVVKANAYGHGL ALR1_ECOLI 26 26 -
EARVWSVVKANAYGHGI ALR2_SALTY 27 27 -
HVHLMAVEKANAYGHGD ALR_BACSU 33 33 -
HAQLMAVVKADGYGHGA ALR_MYCTU 58 58 -
NSKIIAVVKANAYGHGV ALR_HAEIN 28 28 -
MAQLMVVLKADAYGHGA ALR_MYCLE 36 36 -
KTNLMAVVKADAYGHGA ALR_SYNY3 57 57 -

Motif 2 width=19
Element Seqn Id St Int Rpt
LEEAITLRERGWKGPILML ALR2_ECOLI 61 17 -
LEEALRLRAGGITQPILLL ALR1_SALTY 60 17 -
LDEALALREKGIEAPILVL ALR_BACST 67 19 -
LEEALRLRAGGITKPVLLL ALR1_ECOLI 60 17 -
LEEAITLRERGWKGPILML ALR2_SALTY 61 17 -
LDEAISLRKKGLKAPILVL ALR_BACSU 69 19 -
VDEALALRADGITAPVLAW ALR_MYCTU 94 19 -
LEEALALRSNGITKPILLL ALR_HAEIN 63 18 -
VDEALALRADGISAPVLAW ALR_MYCLE 72 19 -
LGEGIELREAGITAPILLL ALR_SYNY3 93 19 -

Motif 3 width=13
Element Seqn Id St Int Rpt
YLKVNSGMNRLGF ALR2_ECOLI 121 41 -
WMKLDTGMHRLGV ALR1_SALTY 120 41 -
HLKMDTGMGRLGV ALR_BACST 127 41 -
WMKLDTGMHRLGV ALR1_ECOLI 120 41 -
YVKVNSGMNRLGF ALR2_SALTY 121 41 -
HLKVDTGMNRLGV ALR_BACSU 128 40 -
TVKVDTGLNRNGV ALR_MYCTU 155 42 -
WLKIDTGMHRLGV ALR_HAEIN 123 41 -
TVKADTGLNRNGV ALR_MYCLE 133 42 -
HLKLDTGMTRLGT ALR_SYNY3 155 43 -

Motif 4 width=12
Element Seqn Id St Int Rpt
TLMSHFAEAEHP ALR2_ECOLI 155 21 -
NIVSHFARADEP ALR1_SALTY 155 22 -
GLYTHFATADEV ALR_BACST 162 22 -
NIVSHFARADEP ALR1_ECOLI 155 22 -
TLMSHFAQADHP ALR2_SALTY 155 21 -
GVFTHFATADEK ALR_BACSU 163 22 -
GLMSHMVYADKP ALR_MYCTU 192 24 -
GFVSHFSRADEL ALR_HAEIN 158 22 -
GLMSHLVYADQP ALR_MYCLE 170 24 -
SLYSHLATADDP ALR_SYNY3 189 21 -

Motif 5 width=28
Element Seqn Id St Int Rpt
SNSAATLWHPEAHFDWVRPGIILYGASP ALR2_ECOLI 190 23 -
AASGGILLWPQSHFDWARPGIILYGVSP ALR1_SALTY 192 25 -
ANSAASLRFPDRTFNMVRFGIAMYGLAP ALR_BACST 202 28 -
AASGGILLWPQSHFDWVRPGIILYGVSP ALR1_ECOLI 192 25 -
SNSAATLWHPQAHYDWVRPGIILYGASP ALR2_SALTY 190 23 -
ANSAAGLRLKKGFFNAVRFGIGMYGLRP ALR_BACSU 203 28 -
SNSSATMARPDLTFDLVRPGIAVYGLSP ALR_MYCTU 235 31 -
AASGGILFWPKSHLECIRPGIIMYGISP ALR_HAEIN 195 25 -
SNSSATMSRPDLAYDLVRPGIAVYGLSP ALR_MYCLE 213 31 -
ANSAATLHGQAWHYDMVRVGLGLYGLYP ALR_SYNY3 232 31 -

Motif 6 width=16
Element Seqn Id St Int Rpt
GERVGYGGRYTARDEQ ALR2_ECOLI 248 30 -
GEPVGYGGTWVSERDT ALR1_SALTY 250 30 -
GEKVSYGATYTAQTEE ALR_BACST 260 30 -
GEPVGYGGTWVSERDT ALR1_ECOLI 250 30 -
GERVGYGGGYSVTQEQ ALR2_SALTY 248 30 -
GESVSYGAEYTAEKDT ALR_BACSU 261 30 -
GEGVSYGHTWIAPRDT ALR_MYCTU 290 27 -
GDPVGYGGIWTSPRDT ALR_HAEIN 251 28 -
GEGVSYGHDWIAQHDT ALR_MYCLE 268 27 -
GTGVSYGHQFVSEETM ALR_SYNY3 288 28 -

Motif 7 width=16
Element Seqn Id St Int Rpt
IGIVAAGYADGYPRHA ALR2_ECOLI 265 1 -
LGVVAMGYGDGYPRAA ALR1_SALTY 267 1 -
IGTIPIGYADGWLRRL ALR_BACST 277 1 -
LGVVAMGYGDGYPRAA ALR1_ECOLI 267 1 -
IGIVAAGYADGYPRHA ALR2_SALTY 265 1 -
IGTVPVGYADGWLRKL ALR_BACSU 278 1 -
LALLPIGYADGVFRSL ALR_MYCTU 307 1 -
IGVVAMGYGDGYPRDV ALR_HAEIN 268 1 -
LALLPVGYADGVFRSL ALR_MYCLE 285 1 -
MAVVGIGYADGVPRNL ALR_SYNY3 305 1 -

Motif 8 width=18
Element Seqn Id St Int Rpt
VLVDGVRTMTVGTVSMDM ALR2_ECOLI 286 5 -
VLVNGREVPIVGRVAMDM ALR1_SALTY 288 5 -
VLVDGQKAPIVGRICMDQ ALR_BACST 297 4 -
VLVNGREVPIVGRVAMDM ALR1_ECOLI 288 5 -
VLVDGIRTRTVGTVSMDM ALR2_SALTY 286 5 -
ILVKGKRLKIAGRICMDQ ALR_BACSU 298 4 -
VLINGRRCPGVGRICMDQ ALR_MYCTU 328 5 -
VYLNGRLVPIVGRVSMDM ALR_HAEIN 289 5 -
VLINGKRRPGVGRICMDQ ALR_MYCLE 306 5 -
VLLRGQPVRQIGAITMDQ ALR_SYNY3 326 5 -

Motif 9 width=14
Element Seqn Id St Int Rpt
TVGYELMCALALRV ALR2_ECOLI 338 34 -
VSAYELITRLTSRV ALR1_SALTY 340 34 -
TINYEVPCTISYRV ALR_BACST 351 36 -
VSAYELITRLTSRV ALR1_ECOLI 340 34 -
TLGYELLCAVAPRV ALR2_SALTY 338 34 -
TINYEVACTISSRV ALR_BACSU 352 36 -
TIHYEVVTSPRGRI ALR_MYCTU 385 39 -
ILSYELITKLTPRV ALR_HAEIN 341 34 -
TIHYEVVTSLRGRI ALR_MYCLE 363 39 -
TISWEILCGFKHRL ALR_SYNY3 382 38 -
Final Motifs
Motif 1  width=17
Element Seqn Id St Int Rpt
HARVWSVVKANAYGHGI ALR2_ECOLI 27 27 -
HARVWSVVKANAYGHGI O87498 27 27 -
ASKLVAVVKANAYGHGL ALR1_SALTY 26 26 -
DTHIMAVVKANAYGHGD ALR_BACST 31 31 -
ASKMVAVVKANAYGHGL ALR1_ECOLI 26 26 -
EARVWSVVKANAYGHGI ALR2_SALTY 27 27 -
GSRLWAVDKDNAYGHGV ALR2_KLEAE 27 27 -
HVHLMAVEKANAYGHGD ALR_BACSU 33 33 -
LTELWAVVKANGYGHGI ALR_LACPL 33 33 -
HAQLMAVVKADGYGHGA ALR_MYCTU 58 58 -
NSKIIAVVKANAYGHGV ALR_HAEIN 28 28 -
SVDLWAVVKANAYGHGI O85045 32 32 -
SADVMAVVKADAYGHGA ALR_MYCSM 38 38 -
MAQLMVVLKADAYGHGA ALR_MYCLE 36 36 -
KSKIMAVVKANGYGHGS ALR2_BACSU 31 31 -
SGHVLAIVKANAYGHGA O59828 30 30 -
KTNLMAVVKADAYGHGA ALR_SYNY3 57 57 -
DACVMAVVKANAYGAGA ALR_HELPY 29 29 -

Motif 2 width=19
Element Seqn Id St Int Rpt
LEEAITLRERGWKGPILML ALR2_ECOLI 61 17 -
LEEAITLRERGWKGPILML O87498 61 17 -
LEEALRLRAGGITQPILLL ALR1_SALTY 60 17 -
LDEALALREKGIEAPILVL ALR_BACST 67 19 -
LEEALRLRAGGITKPVLLL ALR1_ECOLI 60 17 -
LEEAITLRERGWKGPILML ALR2_SALTY 61 17 -
LEEAILLREQGWKGPILLL ALR2_KLEAE 61 17 -
LDEAISLRKKGLKAPILVL ALR_BACSU 69 19 -
LDEALALRAAGFAEPILVL ALR_LACPL 69 19 -
VDEALALRADGITAPVLAW ALR_MYCTU 94 19 -
LEEALALRSNGITKPILLL ALR_HAEIN 63 18 -
LDEALALREAGFQDDFILV O85045 68 19 -
IPEALALREGGITAPVLAW ALR_MYCSM 74 19 -
VDEALALRADGISAPVLAW ALR_MYCLE 72 19 -
VEEGIVLRKAGITAPILVL ALR2_BACSU 67 19 -
IEEALELRHGGIYNKIVLL O59828 68 21 -
LGEGIELREAGITAPILLL ALR_SYNY3 93 19 -
LDEALELRSHFSKTPILIL ALR_HELPY 65 19 -

Motif 3 width=13
Element Seqn Id St Int Rpt
YLKVNSGMNRLGF ALR2_ECOLI 121 41 -
YLKVNSGMNRLGF O87498 121 41 -
WMKLDTGMHRLGV ALR1_SALTY 120 41 -
HLKMDTGMGRLGV ALR_BACST 127 41 -
WMKLDTGMHRLGV ALR1_ECOLI 120 41 -
YVKVNSGMNRLGF ALR2_SALTY 121 41 -
YLKVNSGMNRLGF ALR2_KLEAE 121 41 -
HLKVDTGMNRLGV ALR_BACSU 128 40 -
HLALDTGMGRIGF ALR_LACPL 132 44 -
TVKVDTGLNRNGV ALR_MYCTU 155 42 -
WLKIDTGMHRLGV ALR_HAEIN 123 41 -
HLKVDSGMGRLGI O85045 125 38 -
TVKVDTGLSRNGV ALR_MYCSM 135 42 -
TVKADTGLNRNGV ALR_MYCLE 133 42 -
HINVDTGMGRLGV ALR2_BACSU 130 44 -
WLKLDSGMNRLGF O59828 129 42 -
HLKLDTGMTRLGT ALR_SYNY3 155 43 -
HIKIDTGMHRLGL ALR_HELPY 126 42 -

Motif 4 width=12
Element Seqn Id St Int Rpt
TLMSHFAEAEHP ALR2_ECOLI 155 21 -
TLMSHFAEAEHP O87498 155 21 -
NIVSHFARADEP ALR1_SALTY 155 22 -
GLYTHFATADEV ALR_BACST 162 22 -
NIVSHFARADEP ALR1_ECOLI 155 22 -
TLMSHFAQADHP ALR2_SALTY 155 21 -
TLMSHFAEAENP ALR2_KLEAE 155 21 -
GVFTHFATADEK ALR_BACSU 163 22 -
GIFTHFATADQA ALR_LACPL 168 23 -
GLMSHMVYADKP ALR_MYCTU 192 24 -
GFVSHFSRADEL ALR_HAEIN 158 22 -
GIYTHFATADQL O85045 160 22 -
GLMSHLVHGDDP ALR_MYCSM 172 24 -
GLMSHLVYADQP ALR_MYCLE 170 24 -
GIFTHFSTADEP ALR2_BACSU 165 22 -
GKITHFAFADML O59828 163 21 -
SLYSHLATADDP ALR_SYNY3 189 21 -
GIFTHLSNADAK ALR_HELPY 161 22 -

Motif 5 width=28
Element Seqn Id St Int Rpt
SNSAATLWHPEAHFDWVRPGIILYGASP ALR2_ECOLI 190 23 -
SNSAATLWHPEAHFDWVRPGIILYGRSP O87498 190 23 -
AASGGILLWPQSHFDWARPGIILYGVSP ALR1_SALTY 192 25 -
ANSAASLRFPDRTFNMVRFGIAMYGLAP ALR_BACST 202 28 -
AASGGILLWPQSHFDWVRPGIILYGVSP ALR1_ECOLI 192 25 -
SNSAATLWHPQAHYDWVRPGIILYGASP ALR2_SALTY 190 23 -
ANSAATLWHPEAHFDWVRPGIVLYGASP ALR2_KLEAE 190 23 -
ANSAAGLRLKKGFFNAVRFGIGMYGLRP ALR_BACSU 203 28 -
SNSATSLWHQACNGNMVRFGVALYGLNP ALR_LACPL 208 28 -
SNSSATMARPDLTFDLVRPGIAVYGLSP ALR_MYCTU 235 31 -
AASGGILFWPKSHLECIRPGIIMYGISP ALR_HAEIN 195 25 -
ANSAASLLQPQIGFDAIRFGISMYGLTP O85045 200 28 -
CNSPAAMTRPDLAFEMVRPGISLYGLSP ALR_MYCSM 215 31 -
SNSSATMSRPDLAYDLVRPGIAVYGLSP ALR_MYCLE 213 31 -
CNTAAAIAFPEFSADMIRLGIGLYGLYP ALR2_BACSU 208 31 -
GSAIILGWLNTVCTDWLRAGIMLYGISP O59828 202 27 -
ANSAATLHGQAWHYDMVRVGLGLYGLYP ALR_SYNY3 232 31 -
GILSLCNGNENRLLNLYRPGIMLYGFYP ALR_HELPY 208 35 -

Motif 6 width=16
Element Seqn Id St Int Rpt
GERVGYGGRYTARDEQ ALR2_ECOLI 248 30 -
GERVGYGGRYTARDEQ O87498 248 30 -
GEPVGYGGTWVSERDT ALR1_SALTY 250 30 -
GEKVSYGATYTAQTEE ALR_BACST 260 30 -
GEPVGYGGTWVSERDT ALR1_ECOLI 250 30 -
GERVGYGGGYSVTQEQ ALR2_SALTY 248 30 -
GEAIGYGGLYRTTQEQ ALR2_KLEAE 248 30 -
GESVSYGAEYTAEKDT ALR_BACSU 261 30 -
GKSVSYGATYTAAQDE ALR_LACPL 265 29 -
GEGVSYGHTWIAPRDT ALR_MYCTU 290 27 -
GDPVGYGGIWTSPRDT ALR_HAEIN 251 28 -
GDSVSYGATYTATERE O85045 258 30 -
GDGVSYGHRWVADRDT ALR_MYCSM 270 27 -
GEGVSYGHDWIAQHDT ALR_MYCLE 268 27 -
PRTVSYGATYIAEPNE ALR2_BACSU 267 31 -
GQPIGYGGRYVATRDM O59828 264 34 -
GTGVSYGHQFVSEETM ALR_SYNY3 288 28 -
GEFIGYGEHFYTNEET ALR_HELPY 266 30 -

Motif 7 width=16
Element Seqn Id St Int Rpt
IGIVAAGYADGYPRHA ALR2_ECOLI 265 1 -
IGIVAAGYADGYPRHA O87498 265 1 -
LGVVAMGYGDGYPRAA ALR1_SALTY 267 1 -
IGTIPIGYADGWLRRL ALR_BACST 277 1 -
LGVVAMGYGDGYPRAA ALR1_ECOLI 267 1 -
IGIVAAGYADGYPRHA ALR2_SALTY 265 1 -
IGIVACGYADGYPRVA ALR2_KLEAE 265 1 -
IGTVPVGYADGWLRKL ALR_BACSU 278 1 -
IGTVPIGYADGYERRL ALR_LACPL 282 1 -
LALLPIGYADGVFRSL ALR_MYCTU 307 1 -
IGVVAMGYGDGYPRDV ALR_HAEIN 268 1 -
VATLPIGYADGLIRHY O85045 275 1 -
LGLLPIGYADGVYRAL ALR_MYCSM 287 1 -
LALLPVGYADGVFRSL ALR_MYCLE 285 1 -
IATLPIGYADGYSRAL ALR2_BACSU 284 1 -
LGVVAMGYGDGFPRQV O59828 281 1 -
MAVVGIGYADGVPRNL ALR_SYNY3 305 1 -
VGVLALGYADGLMRAL ALR_HELPY 283 1 -

Motif 8 width=18
Element Seqn Id St Int Rpt
VLVDGVRTMTVGTVSMDM ALR2_ECOLI 286 5 -
VLVDGVRTMTVGTVSMDM O87498 286 5 -
VLVNGREVPIVGRVAMDM ALR1_SALTY 288 5 -
VLVDGQKAPIVGRICMDQ ALR_BACST 297 4 -
VLVNGREVPIVGRVAMDM ALR1_ECOLI 288 5 -
VLVDGIRTRTVGTVSMDM ALR2_SALTY 286 5 -
VLVDGVRTTTVGRVSMDM ALR2_KLEAE 286 5 -
ILVKGKRLKIAGRICMDQ ALR_BACSU 298 4 -
VLVDGEFCEIVGRVCMDQ ALR_LACPL 302 4 -
VLINGRRCPGVGRICMDQ ALR_MYCTU 328 5 -
VYLNGRLVPIVGRVSMDM ALR_HAEIN 289 5 -
VLVDGEPAPIIGRVCMDQ O85045 295 4 -
VLIKGRRRRAVGRICMDQ ALR_MYCSM 308 5 -
VLINGKRRPGVGRICMDQ ALR_MYCLE 306 5 -
VLHRGKRVPVAGRVTMDM ALR2_BACSU 305 5 -
VLVNGVKAPIVGRVSMDM O59828 302 5 -
VLLRGQPVRQIGAITMDQ ALR_SYNY3 326 5 -
VAINNQLAPLIGKVCMDQ ALR_HELPY 304 5 -

Motif 9 width=14
Element Seqn Id St Int Rpt
TVGYELMCALALRV ALR2_ECOLI 338 34 -
TVGYELMCALALRV O87498 338 34 -
VSAYELITRLTSRV ALR1_SALTY 340 34 -
TINYEVPCTISYRV ALR_BACST 351 36 -
VSAYELITRLTSRV ALR1_ECOLI 340 34 -
TLGYELLCAVAPRV ALR2_SALTY 338 34 -
TVGYELMCALAPRV ALR2_KLEAE 338 34 -
TINYEVACTISSRV ALR_BACSU 352 36 -
TIHYEIACGLAPRV ALR_LACPL 356 36 -
TIHYEVVTSPRGRI ALR_MYCTU 385 39 -
ILSYELITKLTPRV ALR_HAEIN 341 34 -
TINYEVTCLLNERI O85045 349 36 -
TIHYEVVTSPRGRV ALR_MYCSM 365 39 -
TIHYEVVTSLRGRI ALR_MYCLE 363 39 -
TINYEVVSTLSRRI ALR2_BACSU 361 38 -
TSPYELVTKLTRRV O59828 356 36 -
TISWEILCGFKHRL ALR_SYNY3 382 38 -
TIAYETISTLSKRL ALR_HELPY 359 37 -