SPRINT Home UMBER Home Contents Standard Search Advanced Search Relation Search

==SPRINT==> PRINTS View



  selected as


PR00895

Identifier
PENTAXIN  [View Relations]  [View Alignment]  
Accession
PR00895
No. of Motifs
7
Creation Date
01-JUL-1998  (UPDATE 10-JUN-1999)
Title
Pentaxin signature
Database References

PROSITE; PS00289 PENTAXIN
PFAM; PF00354 pentaxin
INTERPRO; IPR001759
Literature References
1. GEWURZ, H., ZHANG X.H. AND LINT, T.F.
Structure and function of pentaxins.
CURR.OPIN.IMMUNOL. 7 54-64 (1995).
 
2. ROMERO, I.R., MORRIS, C., RODRIGUEZ, M., DUCLOS, T.W. AND MOLD, C.
Inflammatory potential of C-reactive protein complexes compared to immune
complexes.
CLIN.IMMUN.IMMUNOPATH. 87(2) 155-162 (1998).
 
3. LI, X-A., YUTANI, C. AND SHIMOKADO, K.
Serum amyloid P component associates with high density lipoprotein as well
as very low density lipoprotein but not with low density lipoprotein.
BIOCHEM.BIOPHYS.RES.COMMUN. 244 249-252 (1998).
 
4. COE, J.E AND ROSS, M.J.
Electrophorectic polymorphism of a hamster pentraxin, female protein
SCAND.J.IMMUNOL. 46(2) 180-182 (1997).
 
5. OMEIS, I.A., HSU, Y-C. AND PERIN, M.S.
Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic
structure and chromosomal localization.
GENOMICS 36 543-545 (1996).
 
6. REID, M.S. AND BLOBEL, C.P.
Apexin, an acrosomal pentaxin.
J.BIOL.CHEM. 269 32615-32620 (1994).

Documentation
Pentaxins (or pentraxins) constitute a family of proteins that are involved
in acute immunological responses [1]. Three of the principal members of the 
pentaxin family are serum proteins: namely, C-reactive protein (CRP) [2],
serum amyloid P component protein (SAP) [3], and female protein (FP) [4]. 
CRP is expressed in response to tissue damage or inflammation. The protein
resembles antibody and performs several functions associated with host 
defence: it promotes agglutination, bacterial capsular swelling and phago-
cytosis, and activates the classical complement pathway through its calcium-
dependent binding to phosphocholine. SAP is a vertebrate protein found in 
all types of amyloid deposits, in glomerular basement menbrane and in 
elastic fibres in blood vessels. SAP binds to various lipoprotein ligands
in a calcium-dependent manner, and it has been suggested that, in mammals,
this may have important implications in atherosclerosis and amyloidosis.
FP is a SAP homologue found in the Syrian hamster that is unique because
its synthesis is controlled by sex hormones. 
 
Pentaxin proteins expressed in the nervous system are neural pentaxin I
(NPI) and II (NPII) [5]. NPI and NPII are homologous and can exist within
one species. It is suggested that both proteins mediate the uptake of
synaptic macromolecules and play a role in synaptic plasticity. Apexin, a
sperm acrosomal protein, is a homologue of NPII found in guinea pigs [6].
 
PTX3 (or TSG-14) protein is a cytokine-induced protein that is homologous
to CRPs and SAPs, but its function is not yet known.
 
PENTAXIN is a 7-element fingerprint that provides a signature for the
pentaxin family. The fingerprint was derived from an initial alignment of
10 sequences: the motifs were drawn from the central and C-terminal regions
of the alignment - motif 3 includes the region encoded by PROSITE pattern
PENTAXIN (PS00289), a hexapeptide that includes a cysteine residue known to 
be involved in disulphide bond formation in CRPs and SRPs. Three iterations
on OWL30.2 were required to reach convergence, at which point a true set 
comprising 35 sequences was identified. A single partial match was also
found, LIMU_LIMPO, a limulin fragment from Limulus polyphemus that matches
motifs 1 and 2.
 
An update on SPTR37_9f identified a true set of 32 sequences, and 4
partial matches.
Summary Information
32 codes involving  7 elements
0 codes involving 6 elements
0 codes involving 5 elements
0 codes involving 4 elements
0 codes involving 3 elements
0 codes involving 2 elements
Composite Feature Index
732323232323232
60000000
50000000
40000000
30000000
20000000
1234567
True Positives
APEX_CAVPO    CRP1_LIMPO    CRP3_LIMPO    CRP4_LIMPO    
CRP_CAVPO CRP_HUMAN CRP_MESAU CRP_MOUSE
CRP_RABIT CRP_RAT CRP_XENLA FP_CRIMI
NPX1_HUMAN NPX1_MOUSE NPX1_RAT NPX2_HUMAN
O19062 O19063 O35764 O70340
P79899 P79905 P97738 PTX3_HUMAN
PTX3_MOUSE PXN1_XENLA Q63913 SAMP_CAVPO
SAMP_HUMAN SAMP_MESAU SAMP_MOUSE SAMP_RAT
Sequence Titles
APEX_CAVPO  APEXIN PRECURSOR (ACROSOMAL PENTAXIN-LIKE PROTEIN P50) (AM50) - CAVIA PORCELLUS (GUINEA PIG). 
CRP1_LIMPO C-REACTIVE PROTEIN 1.1 PRECURSOR - LIMULUS POLYPHEMUS (ATLANTIC HORSESHOE CRAB).
CRP3_LIMPO C-REACTIVE PROTEIN 3.3 PRECURSOR - LIMULUS POLYPHEMUS (ATLANTIC HORSESHOE CRAB).
CRP4_LIMPO C-REACTIVE PROTEIN 1.4 PRECURSOR - LIMULUS POLYPHEMUS (ATLANTIC HORSESHOE CRAB).
CRP_CAVPO C-REACTIVE PROTEIN PRECURSOR - CAVIA PORCELLUS (GUINEA PIG).
CRP_HUMAN C-REACTIVE PROTEIN PRECURSOR - HOMO SAPIENS (HUMAN).
CRP_MESAU C-REACTIVE PROTEIN PRECURSOR - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
CRP_MOUSE C-REACTIVE PROTEIN PRECURSOR - MUS MUSCULUS (MOUSE).
CRP_RABIT C-REACTIVE PROTEIN PRECURSOR - ORYCTOLAGUS CUNICULUS (RABBIT).
CRP_RAT C-REACTIVE PROTEIN PRECURSOR - RATTUS NORVEGICUS (RAT).
CRP_XENLA C-REACTIVE PROTEIN PRECURSOR (CRP) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
FP_CRIMI FEMALE PROTEIN PRECURSOR (FP) (SERUM AMYLOID P-COMPONENT) - CRICETULUS MIGRATORIUS (ARMENIAN HAMSTER).
NPX1_HUMAN NEURONAL PENTRAXIN I PRECURSOR (NP-I) (NP1) - HOMO SAPIENS (HUMAN).
NPX1_MOUSE NEURONAL PENTRAXIN I PRECURSOR (NP-I) (NP1) - MUS MUSCULUS (MOUSE).
NPX1_RAT NEURONAL PENTRAXIN I PRECURSOR (NP-I) (NP1) (47 KD TAIPOXIN-BINDING PROTEIN) - RATTUS NORVEGICUS (RAT).
NPX2_HUMAN NEURONAL PENTRAXIN II PRECURSOR (NP-II) (NP2) - HOMO SAPIENS (HUMAN).
O19062 C-REACTIVE PROTEIN PRECURSOR - SUS SCROFA (PIG).
O19063 PORCINE SERUM AMYLOID P COMPONENT (SAP) PRECURSOR (SAP) - SUS SCROFA (PIG).
O35764 NEURONAL PENTRAXIN RECEPTOR - RATTUS NORVEGICUS (RAT).
O70340 NEURONAL PENTRAXIN 2 - MUS MUSCULUS (MOUSE).
P79899 PENTRAXIN PRECURSOR - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
P79905 PENTRAXIN PRECURSOR - SALMO SALAR (ATLANTIC SALMON).
P97738 NARP - RATTUS NORVEGICUS (RAT).
PTX3_HUMAN PENTAXIN-RELATED PROTEIN PTX3 PRECURSOR (TUMOR NECROSIS FACTOR- INDUCIBLE PROTEIN TSG-14) - HOMO SAPIENS (HUMAN).
PTX3_MOUSE PENTAXIN-RELATED PROTEIN PTX3 PRECURSOR (TUMOR NECROSIS FACTOR- INDUCIBLE PROTEIN TSG-14) - MUS MUSCULUS (MOUSE).
PXN1_XENLA PENTRAXIN FUSION PROTEIN PRECURSOR - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
Q63913 SERUM AMYLOID P - CRICETULUS MIGRATORIUS (ARMENIAN HAMSTER).
SAMP_CAVPO SERUM AMYLOID P-COMPONENT PRECURSOR (SAP) - CAVIA PORCELLUS (GUINEA PIG).
SAMP_HUMAN SERUM AMYLOID P-COMPONENT PRECURSOR (SAP) (9.5S ALPHA-1-GLYCOPROTEIN) - HOMO SAPIENS (HUMAN).
SAMP_MESAU SERUM AMYLOID P-COMPONENT PRECURSOR (FEMALE PROTEIN) (FP) (SAP(FP)) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
SAMP_MOUSE SERUM AMYLOID P-COMPONENT PRECURSOR (SAP) - MUS MUSCULUS (MOUSE).
SAMP_RAT SERUM AMYLOID P-COMPONENT PRECURSOR (SAP) - RATTUS NORVEGICUS (RAT).
Scan History
OWL30_2    3  100  NSINGLE    
SPTR37_9f 2 91 NSINGLE
Initial Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
LYSFTICLWLRSSAS APEX_CAVPO 243 243 -
MYAFTVCMWLKSSAA NPX1_RAT 250 250 -
LKNLTVCLRSYTTLT CRP_XENLA 46 46 -
LQEITLCYWFKVNHL CRP4_LIMPO 56 56 -
LESFSACIWVKATDV PTX3_HUMAN 204 204 -
LKAFTLCMKVLLNVP PXN1_XENLA 245 245 -
ISAMTMCQRFNSEQE SGX99385 54 54 -
LEAFTVCLYAHADVS CRP_RAT 49 49 -
LNTFTVCLHFYTALS CRP_MOUSE 49 49 -
LQEFTVCLRAYSDLS SAMP_CAVPO 49 49 -

Motif 2 width=15
Element Seqn Id St Int Rpt
FSYAVPGQANEIVLI APEX_CAVPO 264 6 -
LATSNPLQDNAFLLF CRP_XENLA 68 7 -
FSYNTAKNDNELLTS CRP4_LIMPO 77 6 -
FSYGTKRNPYEIQLY PTX3_HUMAN 225 6 -
FSYRTMFYDELNLWI PXN1_XENLA 267 7 -
FSLATQSHDNDLLLY SGX99385 74 5 -
FSYATKTSFNEILLF CRP_RAT 69 5 -
FSYATKKNSNDILIF CRP_MOUSE 71 7 -
FSYNTPGKDNELLIY SAMP_CAVPO 69 5 -
FSYAVPGQANELVLI NPX1_RAT 271 6 -

Motif 3 width=19
Element Seqn Id St Int Rpt
HICVTWTTRDGVWEAYQDG NPX1_RAT 314 28 -
HVCHTWSSWEGEATIGVDG CRP4_LIMPO 123 31 -
SICWTWDSTTGLTQLWVNG SGX99385 118 29 -
HLCLTWESKYGRTEFWLNG PXN1_XENLA 309 27 -
HLCGTWNSEEGLTSLWVNG PTX3_HUMAN 269 29 -
HICATWESATGIVELWLDG CRP_RAT 112 28 -
HICASWESATGIVEFWIDG CRP_MOUSE 114 28 -
HICTSWESSSGIAEFWING SAMP_CAVPO 112 28 -
HICITWTTRDGLWEAFQDG APEX_CAVPO 307 28 -
HTCVSWDSVSGVVELWIDG CRP_XENLA 111 28 -

Motif 4 width=20
Element Seqn Id St Int Rpt
LHKGYTVGPDASIILGQEQD CRP_MOUSE 140 7 -
LKPDTSVTGTPSIMLVQEQD SGX99385 144 7 -
LQKGYIVGTNASIILGQEQD CRP_RAT 138 7 -
LKRGYSVAAHPKIILGQEQD SAMP_CAVPO 138 7 -
LAPWHPIKSGGVLILGQEQD APEX_CAVPO 334 8 -
LAPYHPIKPQGVLVLGQEQD NPX1_RAT 341 8 -
SKKASSIGFPSSIIQGQEQD CRP_XENLA 137 7 -
IAMGVTLSQGGLVVLGQEQD CRP4_LIMPO 151 9 -
MATGHIVPEGGILQIGQEKN PTX3_HUMAN 296 8 -
YHQKNTVRSGGIVLLGQDQD PXN1_XENLA 335 7 -

Motif 5 width=20
Element Seqn Id St Int Rpt
CVGGGFDETLAFSGRLTGFN PTX3_HUMAN 318 2 -
SYGGDFDKTQSFVGQIKDLK PXN1_XENLA 355 0 -
SYGGDFDAKQSLVGDIGDVN CRP_MOUSE 160 0 -
SYGGGFDANQSLVGDIGDVN CRP_RAT 158 0 -
SYGGKFDRGQSFLGEIGDVY SAMP_CAVPO 158 0 -
SYGGGFDSSQSFVGEVTDVH SGX99385 164 0 -
TVGGRFDATQAFVGELSQFN APEX_CAVPO 354 0 -
TLGGGFDATQAFVGELAHFN NPX1_RAT 361 0 -
SFGGGFNIDQSFVGEISDVH CRP_XENLA 157 0 -
SVGGEYDAEQSLEGELSELN CRP4_LIMPO 171 0 -

Motif 6 width=15
Element Seqn Id St Int Rpt
NIWDSVLSNEEIRET PTX3_HUMAN 337 -1 -
HFWDSVISPCEIQMY SGX99385 183 -1 -
NMWDFVLSPEQINAV CRP_RAT 177 -1 -
NMWDFVLSPEQINTV CRP_MOUSE 179 -1 -
YMWDSVLSPDDVQAV SAMP_CAVPO 177 -1 -
NIWDRVLRPQEISNI APEX_CAVPO 373 -1 -
NIWDRKLTPGEVYNL NPX1_RAT 380 -1 -
HMWDYVLTPDHIQKV CRP_XENLA 176 -1 -
NLWNTVLNHEQIKHL CRP4_LIMPO 190 -1 -
KMWNKVLPLRSLKSL PXN1_XENLA 374 -1 -

Motif 7 width=12
Element Seqn Id St Int Rpt
DFNGNIISWRSL CRP_XENLA 196 5 -
HIRGNIVGWGVT PTX3_HUMAN 358 6 -
IGNGNIFDWSSL PXN1_XENLA 394 5 -
VFSPNVLNWRAL CRP_RAT 196 4 -
FTAGNILNWKDL SGX99385 203 5 -
TLSPNVLNWRAL CRP_MOUSE 198 4 -
YVNGSILNWQAL SAMP_CAVPO 196 4 -
NMAGNIIPWVDN APEX_CAVPO 393 5 -
ALSGNVIAWAES NPX1_RAT 401 6 -
HIHGNIIQWDKT CRP4_LIMPO 214 9 -
Final Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
LENFTLCFRTYTDLS Q63913 49 49 -
LENFTLCFRTYTDLS FP_CRIMI 49 49 -
LQNFTVCFRAYSDLS SAMP_MESAU 52 52 -
LKAFTVCLHFYTELS CRP_HUMAN 48 48 -
LQNFTLCFRAYSDLS SAMP_RAT 50 50 -
LEAFTVCLYAHADVS CRP_RAT 49 49 -
LNTFTVCLHFYTALS CRP_MOUSE 49 49 -
LKAFTVCLHIFTELS CRP_MESAU 49 49 -
LTAFTVCLRVYTDLN O19062 49 49 -
LQNFTLCFRAYSDLS SAMP_HUMAN 49 49 -
LQNFTLCFRTYSDLS SAMP_MOUSE 50 50 -
LSAFTVCLHIYTELF CRP_CAVPO 49 49 -
LKAFTVCLYFYTDLS CRP_RABIT 49 49 -
LQEFTVCLRAYSDLS SAMP_CAVPO 49 49 -
LQNFTLCFRAYSDLS O19063 49 49 -
LYAFTICLWLRSSAS NPX2_HUMAN 246 246 -
LYAFTICLWLRSSAS O70340 245 245 -
LYAFTICLWLRSSAS P97738 248 248 -
LYSFTICLWLRSSAS APEX_CAVPO 243 243 -
MYAFTVCMWLKSSAT NPX1_HUMAN 248 248 -
MYAFTVCMWLKSSAA NPX1_MOUSE 250 250 -
MYAFTVCMWLKSSAA NPX1_RAT 250 250 -
LYAFTACMWLRSRSG O35764 310 310 -
ISAMTMCQRFNSEQE P79905 54 54 -
LQEITLCYWFKVNRL CRP1_LIMPO 56 56 -
LQEITLCYWFKVNCL CRP3_LIMPO 56 56 -
ISAMTMCQRFNSEQE P79899 54 54 -
LKNLTVCLRSYTTLT CRP_XENLA 46 46 -
LQEITLCYWFKVNHL CRP4_LIMPO 56 56 -
LESFSACIWVKATDV PTX3_HUMAN 204 204 -
LKAFTLCMKVLLNVP PXN1_XENLA 245 245 -
LESFSTCIWVKATDV PTX3_MOUSE 204 204 -

Motif 2 width=15
Element Seqn Id St Int Rpt
FSYNTKNKDNELLIY Q63913 69 5 -
FSYNTKNKDNELLIY FP_CRIMI 69 5 -
FSYNAEYGENELLIY SAMP_MESAU 72 5 -
FSYATKRQDNEILIF CRP_HUMAN 70 7 -
FSYSVNSRDNELLIY SAMP_RAT 70 5 -
FSYATKTSFNEILLF CRP_RAT 69 5 -
FSYATKKNSNDILIF CRP_MOUSE 71 7 -
FSYATKNSPNEILIF CRP_MESAU 71 7 -
FSYATKTQYNEILLF O19062 69 5 -
FSYNTQGRDNELLVY SAMP_HUMAN 69 5 -
FSYSVKGRDNELLIY SAMP_MOUSE 70 5 -
FSYATEKEANEILIF CRP_CAVPO 71 7 -
FSYATRRQFNEILLF CRP_RABIT 71 7 -
FSYNTPGKDNELLIY SAMP_CAVPO 69 5 -
FSYNLQGKDNELLVF O19063 69 5 -
FSYAVPGQANEILLI NPX2_HUMAN 267 6 -
FSYAVPGQANEIVLI O70340 266 6 -
FSYAVPGQANEIVLI P97738 269 6 -
FSYAVPGQANEIVLI APEX_CAVPO 264 6 -
FSYAVPGQANELVLI NPX1_HUMAN 269 6 -
FSYAVPGQANELVLI NPX1_MOUSE 271 6 -
FSYAVPGQANELVLI NPX1_RAT 271 6 -
FSYSVPGQANEIVLL O35764 332 7 -
FSLATQSHDNDLLLY P79905 74 5 -
FSYATAKKDNELLTL CRP1_LIMPO 77 6 -
FSYATAKKDNELLTL CRP3_LIMPO 77 6 -
FSLATQSHDNDLLLY P79899 74 5 -
LATSNPLQDNAFLLF CRP_XENLA 68 7 -
FSYNTAKNDNELLTS CRP4_LIMPO 77 6 -
FSYGTKRNPYEIQLY PTX3_HUMAN 225 6 -
FSYRTMFYDELNLWI PXN1_XENLA 267 7 -
FSYGTKWNPYEIQLY PTX3_MOUSE 225 6 -

Motif 3 width=19
Element Seqn Id St Int Rpt
HFCTSWESSSGIADFWVNG Q63913 112 28 -
HFCTSWESSSGIAEFWVNG FP_CRIMI 112 28 -
HFCTSWESSSGIAEFWVNG SAMP_MESAU 115 28 -
HICTSWESASGIVEFWVDG CRP_HUMAN 113 28 -
HFCTSWESSSGIAEFWVNG SAMP_RAT 113 28 -
HICATWESATGIVELWLDG CRP_RAT 112 28 -
HICASWESATGIVEFWIDG CRP_MOUSE 114 28 -
HICASWESATGIAELWVDG CRP_MESAU 114 28 -
HFCMTWESTSGITELWVDG O19062 111 27 -
HICVSWESSSGIAEFWING SAMP_HUMAN 112 28 -
HLCTTWESSSGIVEFWVNG SAMP_MOUSE 113 28 -
HICTSWESVSGIIELWVDG CRP_CAVPO 114 28 -
HLCASWESSTGIAELWVDG CRP_RABIT 114 28 -
HICTSWESSSGIAEFWING SAMP_CAVPO 112 28 -
HICTSWESSTGIAEFWING O19063 112 28 -
HICVTWTTRDGMWEAFQDG NPX2_HUMAN 310 28 -
HICITWTTRDGMWEAFQDG O70340 309 28 -
HICITWTTRDGMWEAFQDG P97738 312 28 -
HICITWTTRDGLWEAFQDG APEX_CAVPO 307 28 -
HICVTWTTRDGVWEAYQDG NPX1_HUMAN 312 28 -
HICVTWTTRDGVWEAYQDG NPX1_MOUSE 314 28 -
HICVTWTTRDGVWEAYQDG NPX1_RAT 314 28 -
HICIAWTTRDGLWSAYQDG O35764 375 28 -
SICWTWDSKSGLTQLWVNG P79905 118 29 -
HVCHTWSSWEGEATIAVDG CRP1_LIMPO 123 31 -
HVCHTWSSWEGEATIAVDG CRP3_LIMPO 123 31 -
SICWTWDSTTGLTQLWVNG P79899 118 29 -
HTCVSWDSVSGVVELWIDG CRP_XENLA 111 28 -
HVCHTWSSWEGEATIGVDG CRP4_LIMPO 123 31 -
HLCGTWNSEEGLTSLWVNG PTX3_HUMAN 269 29 -
HLCLTWESKYGRTEFWLNG PXN1_XENLA 309 27 -
HLCGTWSSEQGSMSLWANG PTX3_MOUSE 269 29 -

Motif 4 width=20
Element Seqn Id St Int Rpt
LKKGYTVKTQPSIILGQEQD Q63913 138 7 -
LKKGYTVKTQPSIILGQEQD FP_CRIMI 138 7 -
LQKGYTVKNKPSIILGQEQD SAMP_MESAU 141 7 -
LKKGYTVGAEASIILGQEQD CRP_HUMAN 139 7 -
LQKGYTVKSSPSIVLGQEQD SAMP_RAT 139 7 -
LQKGYIVGTNASIILGQEQD CRP_RAT 138 7 -
LHKGYTVGPDASIILGQEQD CRP_MOUSE 140 7 -
LQKGYTVGTDASIILGQEQD CRP_MESAU 140 7 -
LKRGYSLGTQASIILGQEQD O19062 137 7 -
LRQGYFVEAQPKIVLGQEQD SAMP_HUMAN 138 7 -
LQREYTVKAPPSIVLGQEQD SAMP_MOUSE 139 7 -
LQKGYFVGTEAMIILGQDQD CRP_CAVPO 140 7 -
LKKGYILGPEASIILGQDQD CRP_RABIT 140 7 -
LKRGYSVAAHPKIILGQEQD SAMP_CAVPO 138 7 -
LRQGYSVGAYPRIVLGQEQD O19063 138 7 -
LAPWHPIKPGGVLILGQEQD NPX2_HUMAN 337 8 -
LAPWHPIKPGGVLILGQEQD O70340 336 8 -
LAPWHPIKPGGVLILGQEQD P97738 339 8 -
LAPWHPIKSGGVLILGQEQD APEX_CAVPO 334 8 -
LAPYHPIKPQGVLVLGQEQD NPX1_HUMAN 339 8 -
LAPYHPIKPQGVLVLGQEQD NPX1_MOUSE 341 8 -
LAPYHPIKPQGVLVLGQEQD NPX1_RAT 341 8 -
LAAWHPIKPHGILILGQEQD O35764 402 8 -
LKPDTSVTGTPSIMLVQEQD P79905 144 7 -
IAVGRTLSQGGLVVLGQDQD CRP1_LIMPO 151 9 -
IAVGRTLSQGGLVVLGQDQD CRP3_LIMPO 151 9 -
LKPDTSVTGTPSIMLVQEQD P79899 144 7 -
SKKASSIGFPSSIIQGQEQD CRP_XENLA 137 7 -
IAMGVTLSQGGLVVLGQEQD CRP4_LIMPO 151 9 -
MATGHIVPEGGILQIGQEKN PTX3_HUMAN 296 8 -
YHQKNTVRSGGIVLLGQDQD PXN1_XENLA 335 7 -
MAKSHSVPEGGLLQIGQEKN PTX3_MOUSE 296 8 -

Motif 5 width=20
Element Seqn Id St Int Rpt
NYGGGFDKSQSFVGEMGDLN Q63913 158 0 -
NYGGGFDKSQSFVGEMGDLN FP_CRIMI 158 0 -
NYGGGFDNYQSFVGEIGDLN SAMP_MESAU 161 0 -
SFGGNFEGSQSLVGDIGNVN CRP_HUMAN 159 0 -
TYGGGFDKTQSFVGEIADLY SAMP_RAT 159 0 -
SYGGGFDANQSLVGDIGDVN CRP_RAT 158 0 -
SYGGDFDAKQSLVGDIGDVN CRP_MOUSE 160 0 -
SYGGGFDANQSLVGDIGDVN CRP_MESAU 160 0 -
AFAGGFEKNQCLVGDIGDVN O19062 157 0 -
SYGGKFDRSQSFVGEIGDLY SAMP_HUMAN 158 0 -
NYGGGFQRSQSFVGEFSDLY SAMP_MOUSE 159 0 -
SFGGSFDANQSFVGDIGDVN CRP_CAVPO 160 0 -
SFGGSFEKQQSLVGDIGNVN CRP_RABIT 160 0 -
SYGGKFDRGQSFLGEIGDVY SAMP_CAVPO 158 0 -
SYGGGFDKTQSFVGEIGDLY O19063 158 0 -
TVGGRFDATQAFVGELSQFN NPX2_HUMAN 357 0 -
TVGGRFDATQAFVGELSQFN O70340 356 0 -
TVGGRFDATQAFVGELSQFN P97738 359 0 -
TVGGRFDATQAFVGELSQFN APEX_CAVPO 354 0 -
TLGGGFDATQAFVGELAHFN NPX1_HUMAN 359 0 -
TLGGGFDATQAFVGELAHFN NPX1_MOUSE 361 0 -
TLGGGFDATQAFVGELAHFN NPX1_RAT 361 0 -
TLGGRFDATQAFVGDIAQFN O35764 422 0 -
SYGGGFDVSQSFVGEVTDVH P79905 164 0 -
SVGGKFDATQSLEGELSELN CRP1_LIMPO 171 0 -
SVGGKFDATQSLEGELSELN CRP3_LIMPO 171 0 -
SYGGGFDSSQSFVGEVTDVH P79899 164 0 -
SFGGGFNIDQSFVGEISDVH CRP_XENLA 157 0 -
SVGGEYDAEQSLEGELSELN CRP4_LIMPO 171 0 -
CVGGGFDETLAFSGRLTGFN PTX3_HUMAN 318 2 -
SYGGDFDKTQSFVGQIKDLK PXN1_XENLA 355 0 -
CVGGGFDESLAFSGRITGFN PTX3_MOUSE 318 2 -

Motif 6 width=15
Element Seqn Id St Int Rpt
NMWDSVLTPEEIKSV Q63913 177 -1 -
NMWDSVLTPEEIKSV FP_CRIMI 177 -1 -
NMWDSVLTPEEIKSV SAMP_MESAU 180 -1 -
NMWDFVLSPDEINTI CRP_HUMAN 178 -1 -
YMWDSVLTPENIHSV SAMP_RAT 178 -1 -
NMWDFVLSPEQINAV CRP_RAT 177 -1 -
NMWDFVLSPEQINTV CRP_MOUSE 179 -1 -
NMWDIVLSPEQINTV CRP_MESAU 179 -1 -
NMWDYVLSPEEINTV O19062 176 -1 -
YMWDSVLPPENILSA SAMP_HUMAN 177 -1 -
YMWDYVLTPQDILFV SAMP_MOUSE 178 -1 -
NMWDFVLSPKEIDMV CRP_CAVPO 179 -1 -
NMWDYALSPEEINTI CRP_RABIT 179 -1 -
YMWDSVLSPDDVQAV SAMP_CAVPO 177 -1 -
YMWGSVLSPNEIRLV O19063 177 -1 -
NIWDRVLRAQEIVNI NPX2_HUMAN 376 -1 -
NIWDRVLRAQEIINI O70340 375 -1 -
NIWDRVLRAQEIINI P97738 378 -1 -
NIWDRVLRPQEISNI APEX_CAVPO 373 -1 -
NIWDRKLTPGEVYNL NPX1_HUMAN 378 -1 -
NIWDRKLTPGEVYNL NPX1_MOUSE 380 -1 -
NIWDRKLTPGEVYNL NPX1_RAT 380 -1 -
NLWDHALTPAQVLGI O35764 441 -1 -
HFWDSVISPCEIQLY P79905 183 -1 -
NLWNTVLNHEQIKYL CRP1_LIMPO 190 -1 -
NLWNTVLNHEQIKYL CRP3_LIMPO 190 -1 -
HFWDSVISPCEIQMY P79899 183 -1 -
HMWDYVLTPDHIQKV CRP_XENLA 176 -1 -
NLWNTVLNHEQIKHL CRP4_LIMPO 190 -1 -
NIWDSVLSNEEIRET PTX3_HUMAN 337 -1 -
KMWNKVLPLRSLKSL PXN1_XENLA 374 -1 -
NIWDRVLSEEEIRAS PTX3_MOUSE 337 -1 -

Motif 7 width=12
Element Seqn Id St Int Rpt
WLEPNILDWRAL Q63913 196 4 -
WLEANILDWRTL FP_CRIMI 196 4 -
PLEPNILDWQAL SAMP_MESAU 199 4 -
PFSPNVLNWRAL CRP_HUMAN 197 4 -
PPNPNILDWRAL SAMP_RAT 197 4 -
VFSPNVLNWRAL CRP_RAT 196 4 -
TLSPNVLNWRAL CRP_MOUSE 198 4 -
TLDPSVLNWQAL CRP_MESAU 198 4 -
TFSPNVLNWRAL O19062 195 4 -
PLPANILDWQAL SAMP_HUMAN 196 4 -
PVNPNILNWQAL SAMP_MOUSE 197 4 -
TFSPNVLSWRSL CRP_CAVPO 198 4 -
TFSPNVLDWREL CRP_RABIT 198 4 -
YVNGSILNWQAL SAMP_CAVPO 196 4 -
FPHPTILDWQAL O19063 197 5 -
NMPGNIIPWVDN NPX2_HUMAN 396 5 -
NMPGNIIPWVDN O70340 395 5 -
NMPGNIIPWVDN P97738 398 5 -
NMAGNIIPWVDN APEX_CAVPO 393 5 -
ALSGNVIAWAES NPX1_HUMAN 399 6 -
ALSGNVIAWAES NPX1_MOUSE 401 6 -
ALSGNVIAWAES NPX1_RAT 401 6 -
PLMGNVLPWEDK O35764 461 5 -
FTPGNILNWKAL P79905 203 5 -
HIYGNIIQWDKT CRP1_LIMPO 214 9 -
HIYGNIIQWDKT CRP3_LIMPO 214 9 -
FTAGNILNWKDL P79899 203 5 -
DFNGNIISWRSL CRP_XENLA 196 5 -
HIHGNIIQWDKT CRP4_LIMPO 214 9 -
HIRGNIVGWGVT PTX3_HUMAN 358 6 -
IGNGNIFDWSSL PXN1_XENLA 394 5 -
HIRGNVVGWGVT PTX3_MOUSE 358 6 -