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PR00509

Identifier
PGMPMM  [View Relations]  [View Alignment]  
Accession
PR00509
No. of Motifs
4
Creation Date
13-JUN-1996  (UPDATE 27-JUN-1999)
Title
Phosphoglucomutase/phosphomannomutase family signature
Database References

PROSITE; PS00710 PGM_PMM
PFAM; PF00408 PGM_PMM
INTERPRO; IPR001485
PDB; 2PMG
SCOP; 3PMG
CATH; 2PMGA; 2PMGB
Literature References
1. DAI, J.B., RAY, W.J. AND KONNO, M.
The crystal structure of muscle phosphoglucomutase refined at 2.7A
resolution.
J.BIOL.CHEM. 267(9) 6322-6337 (1992).
 
2. STEVENSON, G., LEE, S.J., ROMANA, L.K. AND REEVES, P.R.
The cps gene cluster of Salmonella strain LT2 includes a second mannose
pathway - sequence of 2 genes and relationship to genes in the rfb gene
cluster.
MOL.GEN.GENET. 227(2) 173-180 (1991).
 
3. ZIELINSKI, N.A., CHAKRABARTY, A.M AND BERRY, A.
Characterisation and regulation of the Pseudomonas aeruginosa algC gene
encoding phosphomannomutase.
J.BIOL.CHEM. 266(15) 9754-9763 (1991).

Documentation
Phosphoglucomutase (PGM) is responsible for the conversion of D-glucose
1-phosphate to D-glucose 6-phosphate. The enzyme participates in both the
breakdown and synthesis of glucose [1]. Phosphomannomutase (PMM) is
involved in the conversion of D-mannose 1-phosphate to D-mannose
6-phosphate. The enzyme is required for different biosynthetic pathways
in bacteria. In enterobacteria, 2 different genes code for PMM: rfbK,
which is involved in the synthesis of the O antigen of lipopolysaccharide;
and cpsG, which is required for the synthesis of the M antigen capsular
polysaccharide [2]. In P.aeruginosa (gene algC), PMM is involved in the
biosynthesis of the alginate layer [3], and in X.campestris (gene xanA),
it is involved in the biosynthesis of xanthan.
 
The catalytic mechanism of both PGM and PMM involves the formation of a
phosphoserine intermediate [1]. Residues around the active site serine are
well conserved and can be used to characterise a wider PGM/PMM family,
which includes the urease operon ureC protein from H.pylori, E.coli mrsA
protein, P.tetraurelia parafusin (a phosphoglycoprotein involved in
exocytosis), and Methanococcus vannielii hypothetical protein in the
3' region of the gene for ribosomal protein S10.
 
PGMPMM is a 4-element fingerprint that provides a signature for the
phosphogluco- and phosphomannomutase family. The fingerprint was
derived from an initial alignment of 13 sequences: the motifs were
drawn from short conserved regions towards the central portion of the
alignment, motif 1 including the region described by PROSITE pattern
PGM_PMM (PS00710), which includes the active site serine. Three
iterations on OWL28.0 were required to reach convergence, at which
point a true set comprising 28 sequences was identified. Numerous
partial matches were also found, all of which are family members that
fail to make significant matches with one or more motifs. Note: this is 
a highly divergent family, hence the relatively poor diagnositic 
performance of the fingerprint - nevertheless, it may be useful as a guide.
 
An update on SPTR37_9f identified a true set of 48 sequences, and 37
partial matches.
Summary Information
  48 codes involving  4 elements
16 codes involving 3 elements
21 codes involving 2 elements
Composite Feature Index
448484848
31614216
2210021
1234
True Positives
ALGC_PSEAE    EXOC_AZOBR    MANB_ECOLI    MANB_METJA    
MANB_SALMO MANB_SALTY O02605 O02606
O15820 O18719 O25865 O27627
O29791 O43956 O49299 O58651
O66229 O66236 O66240 O66243
O74374 O85343 O86374 P74027
P93262 PARF_PARTE PGM1_YEAST PGM2_YEAST
PGMU_AGRTU PGMU_HUMAN PGMU_NEIGO PGMU_NEIME
PGMU_RABIT PGMU_RAT PGMV_RABIT Q15124
Q21742 Q23919 Q43156 Q50563
Q57439 Q59350 Q59428 RFBB_VIBCH
RFK7_ECOLI RFK9_ECOLI XANA_XANCP YB00_METJA
True Positive Partials
Codes involving 3 elements
MRSA_ECOLI MRSA_HAEIN O06258 O51775
O58973 O66791 O84822 P73648
P95685 P95710 PCM1_YEAST PRSA_PSESY
Q19680 Q49869 Q51847 UREC_HELPY
Codes involving 2 elements
NOEK_RHISN O34824 O53360 O83428
O83648 O84297 O87090 O87164
P72521 P72553 P74643 PCM1_SCHPO
PGMU_ACEXY PGMU_ECOLI Q49913 Q56622
RFBK_SALCH RFBK_SALTY Y740_HAEIN YHXB_BACSU
YM8L_YEAST
Sequence Titles
ALGC_PSEAE  PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - PSEUDOMONAS AERUGINOSA. 
EXOC_AZOBR PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - AZOSPIRILLUM BRASILENSE.
MANB_ECOLI PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - ESCHERICHIA COLI.
MANB_METJA PROBABLE PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - METHANOCOCCUS JANNASCHII.
MANB_SALMO PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - SALMONELLA MONTEVIDEO.
MANB_SALTY PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - SALMONELLA TYPHIMURIUM.
O02605 PHOSPHOGLUCOMUTASE 1 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - PARAMECIUM TETRAURELIA.
O02606 PHOSPHOGLUCOMUTASE 2 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - PARAMECIUM TETRAURELIA.
O15820 PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - ENTAMOEBA HISTOLYTICA.
O18719 PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - ENTAMOEBA DISPAR.
O25865 PHOSPHOMANNOMUTASE (ALGC){PSEUDOMONAS AERUGINOSA} - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O27627 PHOSPHOMANNOMUTASE - METHANOBACTERIUM THERMOAUTOTROPHICUM.
O29791 PHOSPHOMANNOMUTASE (PMM) - ARCHAEOGLOBUS FULGIDUS.
O43956 PHOSPHOGLUCOMUTASE (EC 2.7.5.1) - TETRAHYMENA THERMOPHILA.
O49299 PHOSPHOGLUCOMUTASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O58651 455AA LONG HYPOTHETICAL PHOSPHO-SUGAR MUTASE - PYROCOCCUS HORIKOSHII.
O66229 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - ESCHERICHIA COLI.
O66236 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - ESCHERICHIA COLI.
O66240 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - ESCHERICHIA COLI.
O66243 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - KLEBSIELLA PNEUMONIAE.
O74374 PHOSPHOGLUCOMUTASE - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O85343 PHOSPHOMANNOMUTASE MANB - ESCHERICHIA COLI.
O86374 PMMA - MYCOBACTERIUM TUBERCULOSIS.
P74027 HYPOTHETICAL 52.7 KD PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P93262 PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - MESEMBRYANTHEMUM CRYSTALLINUM (COMMON ICE PLANT).
PARF_PARTE PARAFUSIN - PARAMECIUM TETRAURELIA.
PGM1_YEAST PHOSPHOGLUCOMUTASE 1 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE 1) (PGM 1) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
PGM2_YEAST PHOSPHOGLUCOMUTASE 2 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE 2) (PGM 2) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
PGMU_AGRTU PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - AGROBACTERIUM TUMEFACIENS.
PGMU_HUMAN PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - HOMO SAPIENS (HUMAN).
PGMU_NEIGO PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - NEISSERIA GONORRHOEAE.
PGMU_NEIME PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - NEISSERIA MENINGITIDIS.
PGMU_RABIT PHOSPHOGLUCOMUTASE ISOFORM 1 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - ORYCTOLAGUS CUNICULUS (RABBIT).
PGMU_RAT PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - RATTUS NORVEGICUS (RAT).
PGMV_RABIT PHOSPHOGLUCOMUTASE ISOFORM 2 (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - ORYCTOLAGUS CUNICULUS (RABBIT).
Q15124 PHOSPHOGLUCOMUTASE-RELATED PROTEIN - HOMO SAPIENS (HUMAN).
Q21742 SIMILARTO PHOSPHOGLUCOMUTASE. NCBI GI: 1109809 - CAENORHABDITIS ELEGANS.
Q23919 PHOSPHOGLUCOMUTASE A - DICTYOSTELIUM DISCOIDEUM (SLIME MOLD).
Q43156 PHOSPHOGLUCOMUTASE PRECURSOR (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) - SPINACIA OLERACEA (SPINACH).
Q50563 PHOSPHOMANNOMUTASE - METHANOBACTERIUM THERMOAUTOTROPHICUM.
Q57439 PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - YERSINIA ENTEROCOLITICA.
Q59350 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - ESCHERICHIA COLI.
Q59428 PHOSPHOMANNOMUTASE (EC 5.4.2.8) - ESCHERICHIA COLI, AND KLEBSIELLA PNEUMONIAE.
RFBB_VIBCH PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - VIBRIO CHOLERAE.
RFK7_ECOLI PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - ESCHERICHIA COLI.
RFK9_ECOLI PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - ESCHERICHIA COLI.
XANA_XANCP PHOSPHOGLUCOMUTASE/PHOSPHOMANNOMUTASE [INCLUDES: PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM); PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM)] - XANTHOMONAS CAMPESTRIS (PV. CAMPESTRIS).
YB00_METJA HYPOTHETICAL PROTEIN MJ1100 - METHANOCOCCUS JANNASCHII.

MRSA_ECOLI MRSA PROTEIN - ESCHERICHIA COLI.
MRSA_HAEIN MRSA PROTEIN HOMOLOG - HAEMOPHILUS INFLUENZAE.
O06258 HYPOTHETICAL 45.9 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
O51775 PHOSPHOMANNOMUTASE (CPSG) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O58973 453AA LONG HYPOTHETICAL PHOSPHO-SUGAR MUTASE - PYROCOCCUS HORIKOSHII.
O66791 PHOSPHOGLUCOMUTASE/PHOSPHOMANNOMUTASE - AQUIFEX AEOLICUS.
O84822 PHOSPHOGLUCOMUTASE - CHLAMYDIA TRACHOMATIS.
P73648 HYPOTHETICAL 51.7 KD PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P95685 FEMD GENE - STAPHYLOCOCCUS AUREUS.
P95710 URED GENE - STAPHYLOCOCCUS AUREUS.
PCM1_YEAST PHOSPHOACETYLGLUCOSAMINE MUTASE (EC 5.4.2.3) (ACETYLGLUCOSAMINE PHOSPHOMUTASE) (N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
PRSA_PSESY MRSA PROTEIN HOMOLOG - PSEUDOMONAS SYRINGAE (PV. SYRINGAE).
Q19680 F21D5.1 PROTEIN - CAENORHABDITIS ELEGANS.
Q49869 PUTATIVE UREASE OPERON URED PROTEIN - MYCOBACTERIUM LEPRAE.
Q51847 PHOSPHOMANNOMUTASE - PROCHLOROTHRIX HOLLANDICA.
UREC_HELPY PUTATIVE UREASE OPERON UREC PROTEIN - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).

NOEK_RHISN PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - RHIZOBIUM SP. (STRAIN NGR234).
O34824 YBBT PROTEIN - BACILLUS SUBTILIS.
O53360 PUTATIVE PHOSPHOMANNOMUTASE - MYCOBACTERIUM TUBERCULOSIS.
O83428 PHOSPHOGLUCOMUTASE - TREPONEMA PALLIDUM.
O83648 PHOSPHOMANNOMUTASE (MANB) - TREPONEMA PALLIDUM.
O84297 PHOSPHOMANNOMUTASE - CHLAMYDIA TRACHOMATIS.
O87090 YBBT PROTEIN - BACILLUS SUBTILIS.
O87164 ORF22-25 PROTEIN - VIBRIO CHOLERAE.
P72521 HYPOTHETICAL 44.1 KD PROTEIN - STREPTOCOCCUS PNEUMONIAE.
P72553 CPS3M - STREPTOCOCCUS PNEUMONIAE.
P74643 PHOSPHOGLUCOMUTASE - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
PCM1_SCHPO PUTATIVE PHOSPHOACETYLGLUCOSAMINE MUTASE (EC 5.4.2.3) (ACETYLGLUCOSAMINE PHOSPHOMUTASE) (N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
PGMU_ACEXY PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - ACETOBACTER XYLINUM (ACETOBACTER PASTEURIANUS).
PGMU_ECOLI PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (GLUCOSE PHOSPHOMUTASE) (PGM) - ESCHERICHIA COLI.
Q49913 U0308B - MYCOBACTERIUM LEPRAE.
Q56622 PHOSPHOMANNOMUTASE - VIBRIO CHOLERAE.
RFBK_SALCH PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - SALMONELLA CHOLERAE-SUIS (SALMONELLA ENTERICA).
RFBK_SALTY PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - SALMONELLA TYPHIMURIUM.
Y740_HAEIN PROBABLE PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - HAEMOPHILUS INFLUENZAE.
YHXB_BACSU PROBABLE PHOSPHOMANNOMUTASE (EC 5.4.2.8) (PMM) - BACILLUS SUBTILIS.
YM8L_YEAST HYPOTHETICAL 71.1 KD PROTEIN IN DSK2-CAT8 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
Scan History
OWL28_0    3  500  NSINGLE    
SPTR37_9f 3 200 NSINGLE
Initial Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
SGVMITGSHNPPDYN PGMU_NEIME 96 96 -
SGVMITGSHNPPDYN PGMU_NEIGO 96 96 -
SGVMLTGSHNPPDYN ALGC_PSEAE 100 100 -
GGVMVTASHNPMDYN XANA_XANCP 90 90 -
GGIEVTASHNPMNYN RFK9_ECOLI 91 91 -
GGIEVTASHNPMDYN RFK7_ECOLI 89 89 -
GGIEVTASHNPMDYN CPSG_ECOLI 91 91 -
GGIEVTASHNPMDYN CPSG_SALCH 91 91 -
GGIEVTASHNPMDYN CPSG_SALTY 91 91 -
GGIEVTASHNPMDYN ECOGDPMPP2 89 89 -
GGIEVTASHNPMNYN ECORFBK1 91 91 -
GGIEVTASHNPMNYN ECORFBM1 91 91 -
AGIMITGSHNPPDYN EXOC_AZOBR 99 99 -

Motif 2 width=20
Element Seqn Id St Int Rpt
PLKLVINSGNGAAGPVVDAI CPSG_ECOLI 170 64 -
PLKLVVNSGNGAAGPVIDAI CPSG_SALCH 170 64 -
PLKLVFNAGNGAAGPVIDAI CPSG_SALTY 170 64 -
PLKLVINSGNGAAGPVVDAI ECOGDPMPP2 168 64 -
PLKLVVNSGNGAAGHVIDEV ECORFBK1 171 65 -
PLKLVVNSGNGAAGHVIDEV ECORFBM1 171 65 -
PLKLVINSGNGAAGPVVDAI RFK7_ECOLI 168 64 -
PLKLVVNSGNGAAGHVIDEV RFK9_ECOLI 171 65 -
PLKLVVNAGNGGAGLIVDLL XANA_XANCP 167 62 -
PMKVVVDCGNGVAGVIAPQL ALGC_PSEAE 171 56 -
PINIAIDAGNGVGGAFAGKL PGMU_NEIGO 169 58 -
PMNIAIDAGNGVGGAFAGKL PGMU_NEIME 169 58 -
DLTIAWDAGNGASGEDPAPP EXOC_AZOBR 170 56 -

Motif 3 width=14
Element Seqn Id St Int Rpt
PDGHFPNGIPNPLL ECORFBM1 210 19 -
PDGNFPNGIPNPLL ECOGDPMPP2 207 19 -
PDGTFPNGIPNPLL CPSG_SALTY 209 19 -
PDGTFPNGIPNPLL CPSG_SALCH 209 19 -
PDGNFPNGIPNPLL CPSG_ECOLI 209 19 -
PDGNFPNGIPNPLL RFK7_ECOLI 207 19 -
PDGHFPNGIPNPLL RFK9_ECOLI 210 19 -
PDGNFPNGIPNPLL XANA_XANCP 201 14 -
VDGNFPNHHPDPGK ALGC_PSEAE 205 14 -
VDGNFPNHHPDPSK PGMU_NEIGO 203 14 -
VDGTFPNHHPDPSK PGMU_NEIME 203 14 -
IDGNFPNHHPDPTV EXOC_AZOBR 204 14 -
PDGHFPNGIPNPLL ECORFBK1 210 19 -

Motif 4 width=16
Element Seqn Id St Int Rpt
ADMGIAFDGDFDRCFL CPSG_SALCH 238 15 -
ADMGIAFDGDFDRCFL CPSG_SALTY 238 15 -
ADMGIAFDGDFDRCFL ECOGDPMPP2 236 15 -
ADMGIAFDGDFDRCFL ECORFBK1 239 15 -
ADMGIAFDGDFDRCFL ECORFBM1 239 15 -
ADMGIAFDGDFDRCFL RFK7_ECOLI 236 15 -
ADMGIAFDGDFDRCFL RFK9_ECOLI 239 15 -
ADFGIAWDGDFDRCFF XANA_XANCP 230 15 -
ADLGLAFDGDGDRVGV ALGC_PSEAE 234 15 -
AEIGLAFDGDADRLGV PGMU_NEIGO 232 15 -
AEIGLAFDGDADRLGV PGMU_NEIME 232 15 -
CDIGIGFDGDGDRIGA EXOC_AZOBR 233 15 -
ADMGIAFDGDFDRCFL CPSG_ECOLI 238 15 -
Final Motifs
Motif 1  width=15
Element Seqn Id St Int Rpt
GGIEVTASHNPMDYN MANB_SALMO 91 91 -
GGIEVTASHNPMDYN MANB_ECOLI 91 91 -
GGIEVTASHNPMDYN O85343 91 91 -
GGIEVTASHNPMDYN RFK7_ECOLI 89 89 -
GGIEVTASHNPMDYN MANB_SALTY 91 91 -
GGIEVTASHNPMNYN O66229 91 91 -
GGIEVTASHNPMNYN O66236 91 91 -
GGIEVTASHNPMNYN O66240 91 91 -
GGIEVTASHNPMNYN O66243 91 91 -
GGIEVTASHNPMNYN Q59428 91 91 -
GGIEVTASHNPMNYN RFK9_ECOLI 91 91 -
GGIEVTASHNPIDYN Q59350 91 91 -
GGIEVTASHNPIDYN Q57439 91 91 -
GGIEVTASHNPMDYN RFBB_VIBCH 96 96 -
GGIILTASHNPGGPN PGMU_HUMAN 109 109 -
GGIILTASHNPGGPN PGMU_RABIT 109 109 -
GGIILTASHNPGGPN PGMU_RAT 109 109 -
GGIILTASHNPGGPN PGMV_RABIT 113 113 -
GGVMVTASHNPMDYN XANA_XANCP 90 90 -
GGIILTASHNPGGPK Q21742 114 114 -
GGIILTASHNPGGPE PGM2_YEAST 112 112 -
GGIILTASHNPGGKE O02605 119 119 -
GGIILTASHNPGGKE PARF_PARTE 129 129 -
GGIILTASHNPGGKE O02606 119 119 -
GGIILTASHNPGGPE PGM1_YEAST 113 113 -
GAFILTASHNPGGPN P93262 117 117 -
GAFILTASHNPGGPT O43956 127 127 -
GGIVLSASHNPGGPT PGMU_AGRTU 105 105 -
GAIILTASHNPGGPN Q23919 113 113 -
GAFILTASHNPGGPT O49299 116 116 -
GGIILTASHNAGGPK O74374 106 106 -
GGIILTASHCPGGPG Q15124 54 54 -
SGVMLTGSHNPPDYN ALGC_PSEAE 100 100 -
AGVMITASHNPAPYN O27627 94 94 -
AGFIMTASHNPAGKE O15820 110 110 -
AGFIMTASHNPAGKD O18719 110 110 -
GGVIVTASHNPPQYN Q50563 87 87 -
PGAMFTASHNPAAYN O86374 98 98 -
SGVMITGSHNPPDYN PGMU_NEIGO 96 96 -
SGVMITGSHNPPDYN PGMU_NEIME 96 96 -
AGIMITGSHNPPDYN EXOC_AZOBR 99 99 -
AGVIVTASHNPREYN O29791 93 93 -
GGAVITASHNPPEYN O58651 94 94 -
NSIMITGSHNPKEYN O25865 96 96 -
LGVILTASHNPPEYT MANB_METJA 90 90 -
GSIMMTASHLPYTRN Q43156 145 145 -
VGIMITASHNPPEYN YB00_METJA 82 82 -
GALVLTASHNPANYL P74027 103 103 -

Motif 2 width=20
Element Seqn Id St Int Rpt
PLKLVVNSGNGAAGPVIDAI MANB_SALMO 170 64 -
PLKLVINSGNGAAGPVVDAI MANB_ECOLI 170 64 -
PLKLVINSGNGAAGPVVDAI O85343 170 64 -
PLKLVINSGNGAAGPVVDAI RFK7_ECOLI 168 64 -
PLKLVFNAGNGAAGPVIDAI MANB_SALTY 170 64 -
PLKLVVNSGNGAAGHVIDEV O66229 171 65 -
PLKLVVNSGNGAAGHVIDEV O66236 171 65 -
PLKLVVNSGNGAAGHVIDEV O66240 171 65 -
PLKLVVNSGNGAAGHVIDEV O66243 171 65 -
PLKLVVNSGNGAAGHVIDEV Q59428 171 65 -
PLKLVVNSGNGAAGHVIDEV RFK9_ECOLI 171 65 -
KIKIVVNSGNGAAGPVIDAI Q59350 170 64 -
PLRLVVNSGNGAAGHVIDAL Q57439 170 64 -
PMKLVINSGNGAAGHVIDEL RFBB_VIBCH 173 62 -
RLKIRIDAMHGVVGPYVKKI PGMU_HUMAN 216 92 -
RLKIRIDAMHGVVGPYVKKI PGMU_RABIT 216 92 -
RLKIRIDAMHGVVGPYVKKI PGMU_RAT 216 92 -
RLKIRIDAMHGVVGPYVKKI PGMV_RABIT 220 92 -
PLKLVVNAGNGGAGLIVDLL XANA_XANCP 167 62 -
KLRVLLDSMHGATGPYISTI Q21742 223 94 -
NWKLLFDSMNGVTGPYGKAI PGM2_YEAST 218 91 -
DFSFRFDGMHGVAGPYAKHI O02605 230 96 -
DFSFRFDGMHGVAGPYAKHI PARF_PARTE 240 96 -
DFTFSFDGMHGVAGPYAKHI O02606 230 96 -
GWKLLFDSLNGITGPYGKAI PGM1_YEAST 219 91 -
SFTFCYDALHGVAGVYAKRI P93262 222 90 -
DFQFRFDGMHGVAGPYAHKI O43956 237 95 -
GFKVVVDSMSAVTGPYAVEI PGMU_AGRTU 204 84 -
NFTFNFDAMSGVTGAYGKRI Q23919 217 89 -
KFTFCYDALHGVAGAYAHRI O49299 221 90 -
DFTFVFDALHGITGPYGEAL O74374 207 86 -
QLKIRIDAMHGVMGPYVRKV Q15124 161 92 -
PMKVVVDCGNGVAGVIAPQL ALGC_PSEAE 171 56 -
PLKVVIDSGCGAASHLSPLI O27627 170 61 -
HLKVQVDGFNAVTGIYNKKV O15820 216 91 -
HLKVQVDGFNAVTGIYNKKV O18719 216 91 -
KFRVVVDCGCGAASYTMPYI Q50563 168 66 -
PLRVAVDAGNGMAGHTAPAV O86374 175 62 -
PINIAIDAGNGVGGAFAGKL PGMU_NEIGO 169 58 -
PMNIAIDAGNGVGGAFAGKL PGMU_NEIME 169 58 -
DLTIAWDAGNGASGEDPAPP EXOC_AZOBR 170 56 -
SYRVAVDCGNGAGCFTTPEI O29791 170 62 -
KPFVVVDTSNGAGSLTLPYL O58651 174 65 -
KYKIALDFGNGVGALGLEPI O25865 171 60 -
DKKIAVDFANGATTIAEKEI MANB_METJA 167 62 -
GFQIIVNAGNGSGGFFTWDV Q43156 234 74 -
KFNVVIDCANASACLVSPYL YB00_METJA 159 62 -
KLRVFADVMHGAAASGLERL P74027 184 66 -

Motif 3 width=14
Element Seqn Id St Int Rpt
PDGTFPNGIPNPLL MANB_SALMO 209 19 -
PDGNFPNGIPNPLL MANB_ECOLI 209 19 -
PDGNFPNGIPNPLL O85343 209 19 -
PDGNFPNGIPNPLL RFK7_ECOLI 207 19 -
PDGTFPNGIPNPLL MANB_SALTY 209 19 -
PDGHFPNGIPNPLL O66229 210 19 -
PDGHFPNGIPNPLL O66236 210 19 -
PDGHFPNGIPNPLL O66240 210 19 -
PDGHFPNGIPNPLL O66243 210 19 -
PDGHFPNGIPNPLL Q59428 210 19 -
PDGHFPNGIPNPLL RFK9_ECOLI 210 19 -
PDGNFPHGIPNPLL Q59350 209 19 -
PDGTFPHGIPNPLL Q57439 209 19 -
EDGNFPNGIPNPLL RFBB_VIBCH 212 19 -
PLEDFGGHHPDPNL PGMU_HUMAN 252 16 -
PLEDFGGHHPDPNL PGMU_RABIT 252 16 -
PLEDFGGHHPDPNL PGMU_RAT 252 16 -
PLEDFGGHHPDPNL PGMV_RABIT 256 16 -
PDGNFPNGIPNPLL XANA_XANCP 201 14 -
PKPDFGGGHPDPNL Q21742 259 16 -
PSPDFGGMHPDPNL PGM2_YEAST 255 17 -
PSEDFGGGHPDPNL O02605 266 16 -
PSEDFGGGHPDPNL PARF_PARTE 276 16 -
PSEDFGGGHPDPNL O02606 266 16 -
PLPDFGGLHPDPNL PGM1_YEAST 256 17 -
PKEDFGGGHPDPNL P93262 258 16 -
PKEDFGGGHPDPNL O43956 273 16 -
PLPDFGGHHPDPNL PGMU_AGRTU 240 16 -
PSQDFNGGHPDPNL Q23919 253 16 -
PKEDFGGGHPDPNL O49299 257 16 -
PLPDFGGGHPDPNL O74374 243 16 -
PLEDFGGQHPDPNL Q15124 197 16 -
VDGNFPNHHPDPGK ALGC_PSEAE 205 14 -
PDGFFPGRDPEPVP O27627 204 14 -
PMPDFGGKHPDPNL O15820 252 16 -
PMPDFGGKHPDPNL O18719 252 16 -
PDGFFPGRDPEPVP Q50563 202 14 -
LDGSFPNHEANPLD O86374 210 15 -
VDGNFPNHHPDPSK PGMU_NEIGO 203 14 -
VDGTFPNHHPDPSK PGMU_NEIME 203 14 -
IDGNFPNHHPDPTV EXOC_AZOBR 204 14 -
PDGRFPARNPEPVE O29791 204 14 -
PDGYFPARNPEPNE O58651 208 14 -
PDGNFPNHHPDPSE O25865 205 14 -
PDGNFPAHQPDTLK MANB_METJA 201 14 -
PDGMFPNHIPNPED Q43156 269 15 -
MDGRFIGRLPEPDE YB00_METJA 193 14 -
RDPLFGGASPEPLP P74027 215 11 -

Motif 4 width=16
Element Seqn Id St Int Rpt
ADMGIAFDGDFDRCFL MANB_SALMO 238 15 -
ADMGIAFDGDFDRCFL MANB_ECOLI 238 15 -
ADMGIAFDGDFDRCFL O85343 238 15 -
ADMGIAFDGDFDRCFL RFK7_ECOLI 236 15 -
ADMGIAFDGDFDRCFL MANB_SALTY 238 15 -
ADMGIAFDGDFDRCFL O66229 239 15 -
ADMGIAFDGDFDRCFL O66236 239 15 -
ADMGIAFDGDFDRCFL O66240 239 15 -
ADMGIAFDGDFDRCFL O66243 239 15 -
ADMGIAFDGDFDRCFL Q59428 239 15 -
ADMGIAFDGDFDRCFL RFK9_ECOLI 239 15 -
ADFGIAFDGDFDRCFF Q59350 238 15 -
ADMGIAFDGDFDRCFF Q57439 238 15 -
ADMGIAFDGDFDRCFL RFBB_VIBCH 241 15 -
HDFGAAFDGDGDRNMI PGMU_HUMAN 280 14 -
HDFGAAFDGDGDRNMI PGMU_RABIT 280 14 -
HDFGAAFDGDGDRNMI PGMU_RAT 280 14 -
HDFGAAFDGDGDRNMI PGMV_RABIT 284 14 -
ADFGIAWDGDFDRCFF XANA_XANCP 230 15 -
HDLGAAFDGDGDRNMI Q21742 287 14 -
IEFGAASDGDGDRNMI PGM2_YEAST 283 14 -
PQFGAACDGDADRNMI O02605 301 21 -
PQFGAACDGDADRNMI PARF_PARTE 311 21 -
PQFGAACDGDADRNMI O02606 301 21 -
IAFGAASDGDGDRNMI PGM1_YEAST 284 14 -
PEFGAAADGDADRNMI P93262 293 21 -
PNFGAACDGDADRNMI O43956 310 23 -
PDFGAASDGDGDRNMV PGMU_AGRTU 269 15 -
FDMGCASDGDGDRNMI Q23919 281 14 -
PEFGAAADGDADRNMI O49299 292 21 -
IVMGAASDGDGDRNMI O74374 271 14 -
YGFGAAFDADGDRYMI Q15124 225 14 -
ADLGLAFDGDGDRVGV ALGC_PSEAE 234 15 -
ADLGIAHDGDADRMVA O27627 232 14 -
YDIGFAFDGDGDRNLI O15820 282 16 -
YDIGFAFDGDGDRNLI O18719 282 16 -
ADLGIAHDGDADRTIC Q50563 230 14 -
ADIGLAFDGDADRCFV O86374 239 15 -
AEIGLAFDGDADRLGV PGMU_NEIGO 232 15 -
AEIGLAFDGDADRLGV PGMU_NEIME 232 15 -
CDIGIGFDGDGDRIGA EXOC_AZOBR 233 15 -
ADFGVAHDGDADRAVF O29791 232 14 -
ADFGVAQDGDADRAVF O58651 236 14 -
ISIGFAFDGDADRIAM O25865 234 15 -
CELGLIFDGDGDRLGI MANB_METJA 230 15 -
ADLGIVFDTDVDRSGV Q43156 298 15 -
NYIGIAHDGDADRMVA YB00_METJA 225 18 -
LRVGLIFDGDADRIAA P74027 249 20 -