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PR00465

Identifier
EP450IV  [View Relations]  [View Alignment]  
Accession
PR00465
No. of Motifs
8
Creation Date
25-MAR-1996  (UPDATE 08-JUL-1999)
Title
E-class P450 group IV signature
Database References
PRINTS; PR00385 P450
INTERPRO; IPR002403
PDB; 2HPD
SCOP; 2HPD
CATH; 2HPD
Literature References
1. NOMENCLATURE COMMITTEE OF THE INTERNATIONAL UNION OF BIOCHEMISTRY (NC-IUB).
Nomenclature of electron-transfer proteins. Recommendations 1989.
EUR.J.BIOCHEMISTRY 200 599-611 (1991).
 
2. NEBERT, D.W. AND GONZALEZ, F.J.
P450 genes: structure, evolution, and regulation.
ANNU.REV.BIOCHEMISTRY 56 945-993 (1987).
 
3. NELSON, D.R., KAMATAKI, T., WAXMAN, D.J., GUENGERICH, F.P.,
ESTABROOK, R.W., FEYEREISEN, R., GONZALEZ, F.J., COON, M.J.,
GUNSALUS, I.C., GOTOH, O., OKUDA, K. AND NEBERT, D.W.
The P450 superfamily: update on new sequences, gene mapping, accession
numbers, early trivial names of enzymes, and nomenclature.
DNA CELL BIOL. 12 1-51 (1993).
 
4. GOTOH, O.
Evolution and differentiation of P-450 genes.
IN CYTOCHROME P-450, OMURA, T., ISHIMURA, Y. AND FUJII-KURIYAMA, Y., EDS.
2ND ED., PP.255-272 (1993). KODANSHA, TOKYO.
 
5. HARA, S., MIYATA, A., YOKOYAMA, C., INOUE, H., BRUGGER, R., 
LOTTSPEICH, F., ULLRICH., V. AND TANABE, T.
Isolation and molecular cloning of prostacyclin synthase from bovine 
endothelial cells.
J.BIOL.CHEM. 269 19897-19903 (1994).
 
6. BOSCOTT, P.E. AND GRANT, G.H.
Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from 
P450cam. 
J.MOL.GRAPH. 12 185-192 195 (1994). 

Documentation
P450 enzymes constitute a superfamily of haem-thiolate proteins [1],
widely distributed in bacteria, fungi, plants and animals. The enzymes
are involved in metabolism of a plethora of both exogenous and endogenous
compounds [2]. Usually, they act as terminal oxidases in multi-component
electron transfer chains, called P450-containing monooxygenase systems.
 
Current P450 nomenclature, based on divergent evolution of the P450
superfamily, was proposed and developed by Nebert et al. [3]. On the basis
of sequence similarity, all P450s can be categorised into 2 main classes,
the so-called B- and E-classes: P450 proteins of prokaryotic 3-component
systems and fungal P450nor (CYP55) belong to the B-class; all other known
P450s from distinct systems are of the E-class [4]. E-class P450 may be
further divided into 5 subclasses (groups) according to protein sequence
similarities.
 
There seems to be no particular functional resemblance between cholesterol
7-alpha-hydroxylase (family CYP7) and lanosterol 14-alpha-demethylase 
(CYP51): yet, sequence similarity between these 2 families is significant,
so CYP7 and CYP51 have been regarded as constituting a single group, namely
group IV [4]. Taking into account the high sequence similarity of CYP7 
proteins and prostacyclin synthase (CYP8) [5], we would also include the
CYP8 family within group IV.
 
EP450II is an 8-element fingerprint that provides a signature for group IV
E-class P450s. The fingerprint was derived from an initial alignment
of 7 sequences: the motifs were drawn from conserved regions spanning
virtually the full alignment length. Since there is no 3D structure 
available for a group IV E-class P450 representative, the assignment of
secondary structure elements given below is adopted from the modelling study
of Boscott and Grant [6]. Neighbouring motifs 1 and 2 are located towards
the N-terminus, motif 2 including helix A; motif 3 includes the major part
of helix I, which is proposed to be central to the catalytic function of
P450s (cf. motif 1 of signature P450); motif 5 corresponds to the 
C-terminal half of helix K; motif 6 includes the "aromatic region" typical
of E-class P450s [4]; motifs 7 and 8 are adjacent, spanning the N-terminal
part of helix L and including the invariant Cys residue that provides the
haem iron thiolate ligand (cf. motifs 4 and 5 of signature P450 and
PROSITE pattern CYTOCHROME_P450). Two iterations on OWL27.1 were required
to reach convergence, at which point a true set comprising 21 sequences was
identified. Several partial matches were also found: JC2334 (rat CYP51) is
a fragment lacking motif 1; two more CYP51 sequences (S75389 from Candida
glabrata and S75391 from Issatchenkia orientalis) are fragments lacking
motifs 1 and 8; and, with the exception of two short fragments of yeast
CYP51 (YSA14DM and YSCP450) that match motifs 7 and 8, sequences matching 
five or less motifs belong to other P450 groups.
 
An update on SPTR37_9f identified a true set of 26 sequences, and 308
partial matches.
Summary Information
  26 codes involving  8 elements
0 codes involving 7 elements
1 codes involving 6 elements
4 codes involving 5 elements
13 codes involving 4 elements
94 codes involving 3 elements
195 codes involving 2 elements
Composite Feature Index
82626262626262626
700000000
601110111
512341333
40859110127
301435662686136
212821945836296
12345678
True Positives
CP51_CANAL    CP51_CANGA    CP51_CANTR    CP51_HUMAN    
CP51_PENIT CP51_PIG CP51_RAT CP51_SCHPO
CP51_UNCNE CP51_USTMA CP51_YEAST CP70_CRIGR
CP70_HUMAN CP70_PIG CP70_RABIT CP70_RAT
O02766 O22744 O35074 O75881
O88962 PTGI_BOVIN PTGI_HUMAN Q60991
Q62969 Q64505
True Positive Partials
Codes involving 6 elements
CP09_MYCTU
Codes involving 5 elements
C714_SOLME C81E_GLYEC CP51_SORBI O65814
Codes involving 4 elements
C822_SOYBN C823_SOYBN C824_SOYBN CP3R_ONCMY
CPT7_HUMAN CPXN_ANASP O48925 O65815
O76107 P95099 Q27691 Q59163
Q59990
Codes involving 3 elements
C4D2_DROME C6A1_MUSDO C6B3_PAPPO C6B4_PAPGL
C712_SOLME C751_PETHY C753_PETHY C755_EUSGR
C756_CAMME C757_EUSGR C762_SOLME C76B_HELTU
C7B1_THLAR C7B4_ARATH C7B9_ARATH C7C1_ARATH
C7C2_ARATH C7C4_ARATH C7D7_SOLCH C7DA_SOYBN
C7E1_SORBI C933_SOYBN C982_SOYBN C983_ARATH
CP11_SPAAU CP11_STECH CP26_BRARE CP27_HUMAN
CP27_RAT CP2B_HUMAN CP2B_MOUSE CP2B_RAT
CP36_RABIT CP3D_MOUSE CP42_RAT CP4C_BLADI
CP84_ARATH CPBJ_MOUSE CPCH_HUMAN CPCJ_HUMAN
CPF5_RAT CPH2_CHICK CPM1_HUMAN CPS1_BOVIN
CPS1_HUMAN CPS1_PIG CPS3_PIG CPT7_BOVIN
CPT7_HORSE CPT7_MESAU CPT7_PIG CPT7_SHEEP
O04163 O08447 O16156 O16670
O46051 O46053 O46054 O46221
O46515 O48532 O48918 O49394
O49396 O49650 O49652 O64901
O65782 O69653 O81077 O93323
P77900 P90730 P96813 Q12668
Q16741 Q16742 Q16749 Q16874
Q25508 Q27692 Q27694 Q27703
Q64584 Q64615 Q64639 TCMO_CATRO
TCMO_POPKI TCMO_POPTM THAS_HUMAN THAS_MOUSE
THAS_PIG THAS_RAT
Codes involving 2 elements
AVNA_ASPPA C6A2_DROME C6A9_DROME C6B6_HELAM
C6B7_HELAM C718_MENPI C719_SOYBN C752_SOLME
C754_GENTR C772_SOLME C773_SOYBN C7B2_ARATH
C7B3_ARATH C7B6_ARATH C7B7_ARATH C7C1_MAIZE
C7C2_MAIZE C7C3_ARATH C7C3_MAIZE C7D6_SOLCH
C7D8_SOYBN C7D9_SOYBN C881_MAIZE C883_ARATH
C8B2_ESCCA C931_SOYBN C973_ARATH C981_SORBI
C9B1_GLYEC CP10_LYMST CP11_CANFA CP11_MICTO
CP11_PLEPL CP12_HUMAN CP27_RABIT CP31_RAT
CP32_RAT CP33_HUMAN CP34_HUMAN CP35_HUMAN
CP37_HUMAN CP38_MACFA CP39_RAT CP3A_MESAU
CP3E_CAVPO CP3F_CAVPO CP3G_MOUSE CP3H_CAVPO
CP3I_RAT CP3L_CALJA CP3O_SHEEP CP3P_MOUSE
CP3S_BOVIN CP3T_PIG CP3V_MESAU CP43_RAT
CP44_RABIT CP46_RABIT CP47_RABIT CP4B_RABIT
CP4B_RAT CP4Y_HUMAN CP5I_CANMA CP5T_CANMA
CP71_PERAE CP78_MAIZE CP80_BERST CPB1_RAT
CPB2_RAT CPBB_CANFA CPC7_RAT CPC9_HUMAN
CPCA_HUMAN CPCI_HUMAN CPCP_MESAU CPCQ_MESAU
CPCT_MOUSE CPDA_MOUSE CPF1_RAT CPF2_HUMAN
CPF3_HUMAN CPF4_RAT CPF6_RAT CPH1_CHICK
CPJ2_HUMAN CPM1_BOVIN CPM1_CAPHI CPM1_ONCMY
CPM1_PIG CPM1_RAT CPM1_SHEEP CPN1_BOVIN
CPN1_CAVPO CPN1_HUMAN CPN1_PAPHA CPN1_PIG
CPN1_RANCA CPN1_RAT CPN2_HUMAN CPN2_RAT
CPN3_RAT CPO2_MUSDO CPP1_DROAC CPS1_MOUSE
CPT7_CAVPO CPT7_CHICK CPT7_ICTPU CPT7_ONCMY
CPT7_ORYLA CPT7_RANDY CPT7_RAT CPV1_CARAU
CPV1_ORYLA O01997 O02641 O02646
O13254 O13490 O16362 O16671
O17329 O17655 O17806 O17807
O22185 O22188 O23154 O23155
O23156 O23387 O23389 O23391
O24315 O35728 O42430 O44658
O44704 O45219 O45605 O49342
O53765 O57315 O60634 O61204
O64853 O64989 O65438 O65624
O73852 O74129 O74131 O74133
O74292 O76345 O76799 O76801
O80823 O81725 O86330 O88304
P79716 Q06884 Q08078 Q16757
Q16802 Q16843 Q16872 Q21424
Q27465 Q27466 Q27480 Q27482
Q27693 Q27695 Q42959 Q43795
Q64462 Q64510 Q64529 Q64590
Q92039 STCF_EMENI STCL_EMENI STCS_EMENI
TCMO_ARATH TCMO_CICAR TCMO_GLYEC TCMO_HELTU
TCMO_MEDSA TCMO_PETCR TCMO_PHAAU TCMO_SOYBN
TCMO_ZINEL YRV3_CAEEL YRV7_CAEEL
Sequence Titles
CP51_CANAL  CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - CANDIDA ALBICANS (YEAST). 
CP51_CANGA CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA-DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - CANDIDA GLABRATA (YEAST) (TORULOPSIS GLABRATA).
CP51_CANTR CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - CANDIDA TROPICALIS (YEAST).
CP51_HUMAN CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450L1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (LDM) (P450-14DM) - HOMO SAPIENS (HUMAN).
CP51_PENIT CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (EBURICOL 14-ALPHA-DEMETHYLASE) (P450-14DM) - PENICILLIUM ITALICUM.
CP51_PIG CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450L1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (LDM) (P450-14DM) - SUS SCROFA (PIG).
CP51_RAT CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450L1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (LDM) (P450-14DM) - RATTUS NORVEGICUS (RAT).
CP51_SCHPO PROBABLE CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
CP51_UNCNE CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (EBURICOL 14-ALPHA-DEMETHYLASE) (P450-14DM) - UNCINULA NECATOR (GRAPE POWDERY MILDEW).
CP51_USTMA CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - USTILAGO MAYDIS (SMUT FUNGUS).
CP51_YEAST CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (STEROL 14- ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
CP70_CRIGR CYTOCHROME P450 7 (CHOLESTEROL 7-ALPHA-MONOOXYGENASE) (CYPVII) (EC 1.14.13.17) (CHOLESTEROL 7-ALPHA-HYDROXYLASE) - CRICETULUS GRISEUS (CHINESE HAMSTER).
CP70_HUMAN CYTOCHROME P450 7 (CHOLESTEROL 7-ALPHA-MONOOXYGENASE) (CYPVII) (EC 1.14.13.17) (CHOLESTEROL 7-ALPHA-HYDROXYLASE) - HOMO SAPIENS (HUMAN).
CP70_PIG CYTOCHROME P450 7 (CHOLESTEROL 7-ALPHA-MONOOXYGENASE) (CYPVII) (EC 1.14.13.17) (CHOLESTEROL 7-ALPHA-HYDROXYLASE) - SUS SCROFA (PIG).
CP70_RABIT CYTOCHROME P450 7 (CHOLESTEROL 7-ALPHA-MONOOXYGENASE) (CYPVII) (EC 1.14.13.17) (CHOLESTEROL 7-ALPHA-HYDROXYLASE) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP70_RAT CYTOCHROME P450 7 (CHOLESTEROL 7-ALPHA-MONOOXYGENASE) (CYPVII) (EC 1.14.13.17) (CHOLESTEROL 7-ALPHA-HYDROXYLASE) - RATTUS NORVEGICUS (RAT).
O02766 STEROL 12-ALPHA HYDROXYLASE - ORYCTOLAGUS CUNICULUS (RABBIT).
O22744 PUTATIVE OBTUSIFOLIOL 14-ALPHA DEMETHYLASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O35074 PROSTACYCLIN SYNTHASE (EC 5.3.99.4) (PROSTAGLANDIN-I SYNTHASE) - MUS MUSCULUS (MOUSE).
O75881 OXYSTEROL 7ALPHA-HYDROXYLASE - HOMO SAPIENS (HUMAN).
O88962 STEROL 12-ALPHA HYDROXYLASE CYP8B1 - MUS MUSCULUS (MOUSE).
PTGI_BOVIN PROSTACYCLIN SYNTHASE (EC 5.3.99.4) (PROSTAGLANDIN I2 SYNTHASE) - BOS TAURUS (BOVINE).
PTGI_HUMAN PROSTACYCLIN SYNTHASE (EC 5.3.99.4) (PROSTAGLANDIN I2 SYNTHASE) - HOMO SAPIENS (HUMAN).
Q60991 CYTOCHROME P450, 7B1 (CYTOCHROME P450 CYP7B1) - MUS MUSCULUS (MOUSE).
Q62969 PROSTACYCLIN SYNTHASE - RATTUS NORVEGICUS (RAT).
Q64505 CYTOCHROME P450 (CHOLESTEROL 7-ALPHA-HYDROXYLASE) (EC 1.14.14.1) - MUS MUSCULUS (MOUSE).

CP09_MYCTU CYTOCHROME P450 51-LIKE RV3059 (EC 1.14.-.-) - MYCOBACTERIUM TUBERCULOSIS.

C714_SOLME CYTOCHROME P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE).
C81E_GLYEC CYTOCHROME P450 81E1 (EC 1.14.-.-) (ISOFLAVONE 2'-HYDROXYLASE) (P450 91A4) (CYP GE-3) - GLYCYRRHIZA ECHINATA (LICORICE).
CP51_SORBI CYTOCHROME P450 51 (EC 1.14.14.1) (CYPL1) (P450-L1A1) (OBTUSIFOLIOL 14-ALPHA DEMETHYLASE) - SORGHUM BICOLOR MILO (SORGHUM).
O65814 CYTOCHROME P450 81B1 (EC 1.14.13.53) (ISOFLAVONE 2'-HYDROXYLASE) - HELIANTHUS TUBEROSUS (JERUSALEM ARTICHOKE).

C822_SOYBN CYTOCHROME P450 82A2 (EC 1.14.-.-) (P450 CP4) - GLYCINE MAX (SOYBEAN).
C823_SOYBN CYTOCHROME P450 82A3 (EC 1.14.-.-) (P450 CP6) - GLYCINE MAX (SOYBEAN).
C824_SOYBN CYTOCHROME P450 82A4 (EC 1.14.-.-) (P450 CP9) - GLYCINE MAX (SOYBEAN).
CP3R_ONCMY Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27) - Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
CPT7_HUMAN CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - HOMO SAPIENS (HUMAN).
CPXN_ANASP PROBABLE CYTOCHROME P450 110 (EC 1.14.-.-) (ORF3) - ANABAENA SP. (STRAIN PCC 7120).
O48925 CYP82C1P - GLYCINE MAX (SOYBEAN).
O65815 CYTOCHROME P450 81B1 (EC 1.14.13.53) (ISOFLAVONE 2'-HYDROXYLASE) - HELIANTHUS TUBEROSUS (JERUSALEM ARTICHOKE).
O76107 CYTOCHROME P450 - CULEX QUINQUEFASCIATUS (SOUTHERN HOUSE MOSQUITO).
P95099 HYPOTHETICAL 56.2 KD PROTEIN (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS.
Q27691 CYTOCHROME P450 (EC 1.14.14.1) - MUSCA DOMESTICA (HOUSE FLY).
Q59163 CYTOCHROME P450 (EC 1.14.14.1) - ANABAENA VARIABILIS.
Q59990 CYTOCHROME P450 (EC 1.14.14.1) - SYNECHOCYSTIS SP. (STRAIN PCC 6803).

C4D2_DROME CYTOCHROME P450 4D2 (EC 1.14.14.1) (CYPIVD2) - DROSOPHILA MELANOGASTER (FRUIT FLY).
C6A1_MUSDO CYTOCHROME P450 6A1 (EC 1.14.14.1) (CYPVIA1) - MUSCA DOMESTICA (HOUSE FLY).
C6B3_PAPPO CYTOCHROME P450 6B3 (EC 1.14.14.1) (CYPVIB4) (CYP6B3V1/CYP6B3V2) - PAPILIO POLYXENES (BLACK SWALLOWTAIL BUTTERFLY).
C6B4_PAPGL CYTOCHROME P450 6B4 (EC 1.14.14.1) (CYPVIB4) (CYP6B4V1/CYP6B4V2) - PAPILIO GLAUCUS (TIGER SWALLOWTAIL BUTTERFLY).
C712_SOLME CYTOCHROME P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE).
C751_PETHY FLAVONOID 3',5'-HYDROXYLASE 1 (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A1) (CYPLXXVA1) - PETUNIA HYBRIDA (PETUNIA).
C753_PETHY FLAVONOID 3',5'-HYDROXYLASE 2 (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A3) (CYPLXXVA3) - PETUNIA HYBRIDA (PETUNIA).
C755_EUSGR FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A5) - EUSTOMA GRANDIFLORUM (BLUEBELLS) (LISIANTHUS RUSSELLIANUS).
C756_CAMME FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A6) - CAMPANULA MEDIUM (CANTERBURY BELLS).
C757_EUSGR FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A7) - EUSTOMA GRANDIFLORUM (BLUEBELLS) (LISIANTHUS RUSSELLIANUS).
C762_SOLME CYTOCHROME P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE).
C76B_HELTU CYTOCHROME P450 76B1 (EC 1.14.-.-) (7-ETHOXYCOUMARIN O-DEETHYLASE) (ECOD) (PHENYLUREA DEALKYLASE) - HELIANTHUS TUBEROSUS (JERUSALEM ARTICHOKE).
C7B1_THLAR CYTOCHROME P450 71B1 (EC 1.14.-.-) (CYPLXXIB1) - THLASPI ARVENSE (FIELD PENNYCRESS).
C7B4_ARATH CYTOCHROME P450 71B4 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7B9_ARATH CYTOCHROME P450 71B9 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7C1_ARATH CYTOCHROME P450 76C1 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7C2_ARATH CYTOCHROME P450 76C2 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7C4_ARATH CYTOCHROME P450 76C4 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7D7_SOLCH CYTOCHROME P450 71D7 (EC 1.14.-.-) - SOLANUM CHACOENSE (CHACO POTATO).
C7DA_SOYBN CYTOCHROME P450 71D10 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN).
C7E1_SORBI CYTOCHROME P450 71E1 (EC 1.14.-.-) - SORGHUM BICOLOR MILO (SORGHUM).
C933_SOYBN CYTOCHROME P450 93A3 (EC 1.14.-.-) (P450 CP5) - GLYCINE MAX (SOYBEAN).
C982_SOYBN CYTOCHROME P450 98A2 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN).
C983_ARATH CYTOCHROME P450 98A3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
CP11_SPAAU Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) - Sparus aurata (Gilthead sea bream).
CP11_STECH Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) - Stenotomus chrysops (Scup).
CP26_BRARE CYTOCHROME P450 26 (EC 1.14.-.-) (RETINOIC ACID-METABOLIZING CYTOCHROME) (P450RAI) (RETINOIC ACID 4-HYDROXYLASE) - BRACHYDANIO RERIO (ZEBRAFISH) (ZEBRA DANIO).
CP27_HUMAN STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - HOMO SAPIENS (HUMAN).
CP27_RAT STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - RATTUS NORVEGICUS (RAT).
CP2B_HUMAN 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - HOMO SAPIENS (HUMAN).
CP2B_MOUSE 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - MUS MUSCULUS (MOUSE).
CP2B_RAT 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (25-OHD-1 ALPHA-HYDROXYLASE) (25-HYDROXYVITAMIN D3 1- ALPHA-HYDROXYLASE) (VD3 1A HYDROXYLASE) (P450C1 ALPHA) (P450VD1- ALPHA) - RATTUS NORVEGICUS (RAT).
CP36_RABIT Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C) - Oryctolagus cuniculus (Rabbit).
CP3D_MOUSE Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13) - Mus musculus (Mouse).
CP42_RAT CYTOCHROME P450 4A2 PRECURSOR (EC 1.14.15.3) (CYPIVA2) (LAURIC ACID OMEGA-HYDROXYLASE) (P450-LA-OMEGA 2) (P450 K-5) (P-450 K-2) - RATTUS NORVEGICUS (RAT).
CP4C_BLADI CYTOCHROME P450 4C1 (EC 1.14.14.1) (CYPIVC1) - BLABERUS DISCOIDALIS (TROPICAL COCKROACH).
CP84_ARATH CYTOCHROME P450 84A1 (FERULATE-5-HYDROXYLASE) (EC 1.14.-.-) (F5H) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
CPBJ_MOUSE Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19) - Mus musculus (Mouse).
CPCH_HUMAN CYTOCHROME P450 2C19 (EC 1.14.14.1) (CYPIIC19) (P450-11A) (MEPHENYTOIN 4-HYDROXYLASE) (CYPIIC17) (P450-254C) - HOMO SAPIENS (HUMAN).
CPCJ_HUMAN CYTOCHROME P450 2C19 (EC 1.14.14.1) (CYPIIC19) (P450-11A) (MEPHENYTOIN 4-HYDROXYLASE) (CYPIIC17) (P450-254C) - HOMO SAPIENS (HUMAN).
CPF5_RAT CYTOCHROME P450 4F5 (EC 1.14.14.1) (CYPIVF5) - RATTUS NORVEGICUS (RAT).
CPH2_CHICK CYTOCHROME P450 2H2 (EC 1.14.14.1) (CYPIIH2) (P450 PCHP7) - GALLUS GALLUS (CHICKEN).
CPM1_HUMAN CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - HOMO SAPIENS (HUMAN).
CPS1_BOVIN CYTOCHROME P450 XXIA1 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - BOS TAURUS (BOVINE).
CPS1_HUMAN CYTOCHROME P450 XXIB (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21B) - HOMO SAPIENS (HUMAN).
CPS1_PIG CYTOCHROME P450 XXIA1 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - SUS SCROFA (PIG).
CPS3_PIG CYTOCHROME P450 XXIA3 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - SUS SCROFA (PIG).
CPT7_BOVIN CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - BOS TAURUS (BOVINE).
CPT7_HORSE CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - EQUUS CABALLUS (HORSE).
CPT7_MESAU CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
CPT7_PIG CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - SUS SCROFA (PIG).
CPT7_SHEEP CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - OVIS ARIES (SHEEP).
O04163 CYTOCHROME P450 - NEPETA RACEMOSA.
O08447 PUTATIVE CYTOCHROME P450 MONOXYGENASE (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS.
O16156 CYTOCHROME P450 30 - MERCENARIA MERCENARIA (NORTHERN QUAHOG).
O16670 F41B5.4 PROTEIN - CAENORHABDITIS ELEGANS.
O46051 EG:152A3.2 PROTEIN - DROSOPHILA MELANOGASTER (FRUIT FLY).
O46053 COSMID 152A3 - DROSOPHILA MELANOGASTER (FRUIT FLY).
O46054 COSMID 152A3 - DROSOPHILA MELANOGASTER (FRUIT FLY).
O46221 CYTOCHROME P450 MONOOXYGENASE CYP28A1 - DROSOPHILA METTLERI (FRUIT FLY).
O46515 CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE - EQUUS CABALLUS (HORSE).
O48532 PUTATIVE CYTOCHROME P-450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O48918 CYP71A10 - GLYCINE MAX (SOYBEAN).
O49394 CYTOCHROME P450-LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O49396 CYTOCHROME P450-LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O49650 CYTOCHROME P450 LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O49652 CYTOCHROME P450 - LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O64901 (S)-N-METHYLCOCLAURINE 3'-HYDROXYLASE - ESCHSCHOLZIA CALIFORNICA (CALIFORNIA POPPY).
O65782 CYTOCHROME P450 MONOOXYGENASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O69653 PUTATIVE CYTOCHROME P-450 - MYCOBACTERIUM TUBERCULOSIS.
O81077 PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O93323 RETINOIC ACID CONVERTING ENZYME - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
P77900 HYPOTHETICAL 52.2 KD PROTEIN CY21B4.11C (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS.
P90730 CYTOCHROME P450 (EC 1.14.14.1) - CERATITIS CAPITATA (MEDITERRANEAN FRUIT FLY).
P96813 HYPOTHETICAL 49.3 KD PROTEIN (EC 1.14.14.1) - MYCOBACTERIUM TUBERCULOSIS.
Q12668 CYTOCHROME P450 (BENZOATE 4-HYDROXYLASE) (EC 1.14.14.1) - RHODOTORULA MINUTA.
Q16741 CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE). (EC 1.14.14.1) - HOMO SAPIENS (HUMAN).
Q16742 CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) - HOMO SAPIENS (HUMAN).
Q16749 CYTOCHROME P450 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) - HOMO SAPIENS (HUMAN).
Q16874 CYTOCHROME P450 21-HYDROXYLASE (STEROID 21-MONOOXYGENASE) (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (CYTOCHROME P450 XXIA1) - HOMO SAPIENS (HUMAN).
Q25508 CYTOCHROME P450 - MANDUCA SEXTA (TOBACCO HAWKMOTH) (TOBACCO HORNWORM).
Q27692 CYTOCHROME P450 (EC 1.14.14.1) - MUSCA DOMESTICA (HOUSE FLY).
Q27694 CYTOCHROME P450 (EC 1.14.14.1) - MUSCA DOMESTICA (HOUSE FLY).
Q27703 CYTOCHROME P450 (EC 1.14.14.1) - MUSCA DOMESTICA (HOUSE FLY).
Q64584 CYTOCHROME P450 B (EC 1.14.14.1) - Rattus norvegicus (Rat).
Q64615 CYTOCHROME P450 C27/25 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT).
Q64639 CYTOCHROME P450 C27/25 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT).
TCMO_CATRO TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - CATHARANTHUS ROSEUS (ROSY PERIWINKLE) (MADAGASCAR PERIWINKLE).
TCMO_POPKI TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - POPULUS KITAKAMIENSIS (ASPEN).
TCMO_POPTM TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - POPULUS TREMULOIDES (QUAKING ASPEN).
THAS_HUMAN THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - HOMO SAPIENS (HUMAN).
THAS_MOUSE THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) (TS) - MUS MUSCULUS (MOUSE).
THAS_PIG THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - SUS SCROFA (PIG).
THAS_RAT THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS) - RATTUS NORVEGICUS (RAT).

AVNA_ASPPA AVERANTIN OXIDOREDUCTASE (EC 1.14.-.-) (CYTOCHROME P450 60A1) - ASPERGILLUS PARASITICUS.
C6A2_DROME CYTOCHROME P450 6A2 (EC 1.14.14.1) (CYPVIA2) (P450-B1) - DROSOPHILA MELANOGASTER (FRUIT FLY).
C6A9_DROME CYTOCHROME P450 6A9 (EC 1.14.14.1) (CYPVIA9) - DROSOPHILA MELANOGASTER (FRUIT FLY).
C6B6_HELAM CYTOCHROME P450 6B6 (EC 1.14.14.1) (CYPVIB6) - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
C6B7_HELAM CYTOCHROME P450 6B7 (EC 1.14.14.1) (CYPVIB7) - HELICOVERPA ARMIGERA (COTTON BOLLWORM).
C718_MENPI CYTOCHROME P450 71A8 (EC 1.14.-.-) - MENTHA PIPERITA (PEPPERMINT).
C719_SOYBN CYTOCHROME P450 71A9 (EC 1.14.-.-) (P450 CP1) - GLYCINE MAX (SOYBEAN).
C752_SOLME FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A2) (CYPLXXVA2) (P-450EG1) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE).
C754_GENTR FLAVONOID 3',5'-HYDROXYLASE (EC 1.14.-.-) (F3'5'H) (CYTOCHROME P450 75A4) - GENTIANA TRIFLORA.
C772_SOLME CYTOCHROME P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2) (P-450EG5) - SOLANUM MELONGENA (EGGPLANT) (AUBERGINE).
C773_SOYBN CYTOCHROME P450 77A3 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN).
C7B2_ARATH CYTOCHROME P450 71B2 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7B3_ARATH CYTOCHROME P450 71B3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7B6_ARATH CYTOCHROME P450 71B6 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7B7_ARATH CYTOCHROME P450 71B7 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7C1_MAIZE CYTOCHROME P450 71C1 (EC 1.14.-.-) - ZEA MAYS (MAIZE).
C7C2_MAIZE CYTOCHROME P450 71C2 (EC 1.14.-.-) - ZEA MAYS (MAIZE).
C7C3_ARATH CYTOCHROME P450 76C3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C7C3_MAIZE CYTOCHROME P450 71C3 (EC 1.14.-.-) - ZEA MAYS (MAIZE).
C7D6_SOLCH CYTOCHROME P450 71D6 (EC 1.14.-.-) - SOLANUM CHACOENSE (CHACO POTATO).
C7D8_SOYBN CYTOCHROME P450 71D8 (EC 1.14.-.-) (P450 CP7) - GLYCINE MAX (SOYBEAN).
C7D9_SOYBN CYTOCHROME P450 71D9 (EC 1.14.-.-) (P450 CP3) - GLYCINE MAX (SOYBEAN).
C881_MAIZE CYTOCHROME P450 88A1 (EC 1.14.-.-) (DWARF3 PROTEIN) - ZEA MAYS (MAIZE).
C883_ARATH CYTOCHROME P450 88A3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C8B2_ESCCA (S)-N-METHYLCOCLAURINE 3'-HYDROXYLASE ISOZYME 2 (EC 1.1.3.-) (CYTOCHROME P450 80B2) - ESCHSCHOLZIA CALIFORNICA (CALIFORNIA POPPY).
C931_SOYBN CYTOCHROME P450 93A1 (EC 1.14.-.-) - GLYCINE MAX (SOYBEAN).
C973_ARATH CYTOCHROME P450 97B3 (EC 1.14.-.-) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
C981_SORBI CYTOCHROME P450 98A1 (EC 1.14.-.-) - SORGHUM BICOLOR MILO (SORGHUM).
C9B1_GLYEC CYTOCHROME P450 93B1 (EC 1.14.-.-) ((2S)-FLAVANONE 2-HYDROXYLASE) (LICODIONE SYNTHASE) (FLAVONE SYNTHASE II) (CYP GE-5) - GLYCYRRHIZA ECHINATA (LICORICE).
CP10_LYMST CYTOCHROME P450 10 (EC 1.14.-.-) (CYPX) - LYMNAEA STAGNALIS (GREAT POND SNAIL).
CP11_CANFA Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (DAH1) - Canis familiaris (Dog).
CP11_MICTO Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) - Microgadus tomcod (Atlantic tomcod).
CP11_PLEPL Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) - Pleuronectes platessa (Plaice).
CP12_HUMAN Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3) (P(3)450) (P450 4) - Homo sapiens (Human).
CP27_RABIT STEROL 26-HYDROXYLASE, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP31_RAT Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1) - Rattus norvegicus (Rat).
CP32_RAT Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2) (P450/6- beta-A) (Testosterone 6-beta-hydroxylase) - Rattus norvegicus (Rat).
CP33_HUMAN Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp) - Homo sapiens (Human).
CP34_HUMAN Cytochrome P450 3A4 (EC 1.14.14.1) (CYPIIIA4) (Nifedipine oxidase) (NF-25) (P450-PCN1) - Homo sapiens (Human).
CP35_HUMAN Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3) - Homo sapiens (Human).
CP37_HUMAN Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA) - Homo sapiens (Human).
CP38_MACFA Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2) (P-450- MK2) - Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey).
CP39_RAT Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3) (Olfactive) (3AH15) - Rattus norvegicus (Rat).
CP3A_MESAU Cytochrome P450 3A10 (EC 1.14.14.1) (CYPIIIA10) (6 beta-hydroxylase) - Mesocricetus auratus (Golden hamster).
CP3E_CAVPO Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14) - Cavia porcellus (Guinea pig).
CP3F_CAVPO Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15) - Cavia porcellus (Guinea pig).
CP3G_MOUSE Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16) - Mus musculus (Mouse).
CP3H_CAVPO Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17) - Cavia porcellus (Guinea pig).
CP3I_RAT Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18) (P450(6)beta-2) - Rattus norvegicus (Rat).
CP3L_CALJA Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450 CM3A-10) - Callithrix jacchus (Common marmoset).
CP3O_SHEEP Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) - Ovis aries (Sheep).
CP3P_MOUSE Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25) - Mus musculus (Mouse).
CP3S_BOVIN Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28) - Bos taurus (Bovine).
CP3T_PIG Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29) - Sus scrofa (Pig).
CP3V_MESAU Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450 SH3A-1) - Mesocricetus auratus (Golden hamster).
CP43_RAT CYTOCHROME P450 4A3 (EC 1.14.15.3) (CYPIVA3) (LAURIC ACID OMEGA- HYDROXYLASE) (P450-LA-OMEGA 3) - RATTUS NORVEGICUS (RAT).
CP44_RABIT CYTOCHROME P450 4A4 (EC 1.14.14.1) (CYPIVA4) (PROSTAGLANDIN OMEGA- HYDROXYLASE) (P450-P-2) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP46_RABIT CYTOCHROME P450 4A6 PRECURSOR (EC 1.14.15.3) (CYPIVA6) (LAURIC ACID OMEGA-HYDROXYLASE) (P450-KA-1) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP47_RABIT CYTOCHROME P450 4A7 PRECURSOR (EC 1.14.15.3) (CYPIVA7) (LAURIC ACID OMEGA-HYDROXYLASE) (P450-KA-2) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP4B_RABIT CYTOCHROME P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-ISOZYME 5) - ORYCTOLAGUS CUNICULUS (RABBIT).
CP4B_RAT CYTOCHROME P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-ISOZYME 5) - RATTUS NORVEGICUS (RAT).
CP4Y_HUMAN CYTOCHROME P450 4A11 PRECURSOR (EC 1.14.15.3) (CYPIVA11) (FATTY ACID OMEGA- HYDROXYLASE) (P-450 HK OMEGA) (LAURIC ACID OMEGA-HYDROXYLASE) (CYP4AII) (P450-HL-OMEGA) - HOMO SAPIENS (HUMAN).
CP5I_CANMA CYTOCHROME P450 52A9 (EC 1.14.14.1) (CYPLIIA9) (ALKANE-INDUCIBLE P450-ALK5-A) -
CP5T_CANMA CYTOCHROME P450 52D1 (EC 1.14.14.-) (CYPLIID1) (ALKANE-INDUCIBLE P450-ALK4) - CA
CP71_PERAE CYTOCHROME P450 71A1 (EC 1.14.-.-) (CYPLXXIA1) (ARP-2) - PERSEA AMERICANA (AVOCADO).
CP78_MAIZE CYTOCHROME P450 78A1 (EC 1.14.-.-) (CYPLXXVIII) - ZEA MAYS (MAIZE).
CP80_BERST BERBAMUNINE SYNTHASE (EC 1.1.3.34) (CYTOCHROME P450 80) (CYPLXXX) ((S)-N-METHYLCOCLAURINE OXIDASE [C-O PHENOL-COUPLING]) - BERBERIS STOLONIFERA (BARBERRY).
CPB1_RAT Cytochrome P450 2B1 (EC 1.14.14.1) (CYPIIB1) (P450-B) (P450-PB1 and P450-PB2) (P450-LM2) - Rattus norvegicus (Rat).
CPB2_RAT Cytochrome P450 2B2 (EC 1.14.14.1) (CYPIIB2) (P450E) (P450 PB4) - Rattus norvegicus (Rat).
CPBB_CANFA Cytochrome P450 2B11 (EC 1.14.14.1) (CYPIIB11) (P450 PBD-2) - Canis familiaris (Dog).
CPC7_RAT CYTOCHROME P450 2C7 (EC 1.14.14.1) (CYPIIC7) (P450F) (PTF1) - RATTUS NORVEGICUS (RAT).
CPC9_HUMAN CYTOCHROME P450 2C9 (EC 1.14.14.1) (CYPIIC9) (P450 PB-1) (P450 MP-4) (S-MEPHENYTOIN 4-HYDROXYLASE) (P-450MP) - HOMO SAPIENS (HUMAN).
CPCA_HUMAN CYTOCHROME P450 2C10 (EC 1.14.14.1) (CYPIIC10) (P450 MP-8) (S- MEPHENYTOIN 4-HYDROXYLASE) (P-450MP) - HOMO SAPIENS (HUMAN).
CPCI_HUMAN CYTOCHROME P450 2C18 (EC 1.14.14.1) (CYPIIC18) (P450-6B/29C) - HOMO SAPIENS (HUMAN).
CPCP_MESAU CYTOCHROME P450 2C26 (EC 1.14.14.1) (CYPIIC26) (P450 HSM2) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
CPCQ_MESAU CYTOCHROME P450 2C27 (EC 1.14.14.1) (CYPIIC27) (P450 HSM3) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
CPCT_MOUSE CYTOCHROME P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P-450 MUT-2) (ALDEHYDE OXYGENASE) - MUS MUSCULUS (MOUSE).
CPDA_MOUSE Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) - Mus musculus (Mouse).
CPF1_RAT CYTOCHROME P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3) - RATTUS NORVEGICUS (RAT).
CPF2_HUMAN CYTOCHROME P450 4F2 (EC 1.14.13.30) (CYPIVF2) (LEUKOTRIENE-B4 OMEGA- HYDROXYLASE) (LEUKOTRIENE-B4 20-MONOOXYGENASE) (CYTOCHROME P450- LTB-OMEGA) - HOMO SAPIENS (HUMAN).
CPF3_HUMAN CYTOCHROME P450 4F3 (EC 1.14.13.30) (CYPIVF3) (LEUKOTRIENE-B4 OMEGA- HYDROXYLASE) (LEUKOTRIENE-B4 20-MONOOXYGENASE) (CYTOCHROME P450- LTB-OMEGA) - HOMO SAPIENS (HUMAN).
CPF4_RAT CYTOCHROME P450 4F4 (EC 1.14.14.1) (CYPIVF4) - RATTUS NORVEGICUS (RAT).
CPF6_RAT CYTOCHROME P450 4F6 (EC 1.14.14.1) (CYPIVF6) - RATTUS NORVEGICUS (RAT).
CPH1_CHICK CYTOCHROME P450 2H1 (EC 1.14.14.1) (CYPIIH1) (PB15) (P450 PCHP3) - GALLUS GALLUS (CHICKEN).
CPJ2_HUMAN Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic acid epoxygenase) - Homo sapiens (Human).
CPM1_BOVIN CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - BOS TAURUS (BOVINE).
CPM1_CAPHI CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - CAPRA HIRCUS (GOAT).
CPM1_ONCMY CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
CPM1_PIG CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - SUS SCROFA (PIG).
CPM1_RAT CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - RATTUS NORVEGICUS (RAT).
CPM1_SHEEP CYTOCHROME P450 11A1, MITOCHONDRIAL PRECURSOR (EC 1.14.15.6) (CYPXIA1) (P450(SCC)) (CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME) (CHOLESTEROL DESMOLASE) - OVIS ARIES (SHEEP).
CPN1_BOVIN CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - BOS TAURUS (BOVINE).
CPN1_CAVPO CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (ALDOSTERONE SYNTHASE) - CAVIA PORCELLUS (GUINEA PIG).
CPN1_HUMAN CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - HOMO SAPIENS (HUMAN).
CPN1_PAPHA CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - PAPIO HAMADRYAS (HAMADRYAS BABOON).
CPN1_PIG CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) - SUS SCROFA (PIG).
CPN1_RANCA CYTOCHROME P450 11B PRECURSOR (EC 1.14.15.4) (CYPXIB) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (P-450(11 BETA,ALDO)) - RANA CATESBEIANA (BULL FROG).
CPN1_RAT CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4) (CYPXIB1) (P450C11) (STEROID 11-BETA-HYDROXYLASE) (P450(11 BETA)-DS) - RATTUS NORVEGICUS (RAT).
CPN2_HUMAN CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (CYPXIB2) (P-450ALDO) (ALDOSTERONE SYNTHASE) (ALDOS) (ALDOSTERONE-SYNTHESIZING ENZYME) (STEROID 18-HYDROXYLASE) (P-450C18) - HOMO SAPIENS (HUMAN).
CPN2_RAT CYTOCHROME P450 11B2 PRECURSOR (EC 1.14.15.4) (CYPXIB2) (P450-ALDO-1) (ALDOSTERONE SYNTHASE) - RATTUS NORVEGICUS (RAT).
CPN3_RAT CYTOCHROME P450 11B3 PRECURSOR (EC 1.14.15.4) (CYPXIB3) (P450-ALDO-2) (ALDOSTERONE SYNTHASE) - RATTUS NORVEGICUS (RAT).
CPO2_MUSDO CYTOCHROME P450 CYP12A2 (EC 1.14.-.-) (CYPXIIA2) - MUSCA DOMESTICA (HOUSE FLY).
CPP1_DROAC CYTOCHROME P450 12B1 PRECURSOR (EC 1.14.-.-) (CYPXIIB1) - DROSOPHILA ACANTHOPTERA (FRUIT FLY).
CPS1_MOUSE CYTOCHROME P450 XXIA1 (EC 1.14.99.10) (STEROID 21-HYDROXYLASE) (P450-C21) - MUS MUSCULUS (MOUSE).
CPT7_CAVPO CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - CAVIA PORCELLUS (GUINEA PIG).
CPT7_CHICK CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - GALLUS GALLUS (CHICKEN).
CPT7_ICTPU CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ICTALURUS PUNCTATUS (CHANNEL CATFISH).
CPT7_ONCMY CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ONCORHYNCHUS MYKISS (RAINBOW TROUT) (SALMO GAIRDNERI).
CPT7_ORYLA CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - ORYZIAS LATIPES (MEDAKA FISH).
CPT7_RANDY CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - RANA DYBOWSKII (FROG).
CPT7_RAT CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII) (P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE) - RATTUS NORVEGICUS (RAT).
CPV1_CARAU CYTOCHROME P450 19 (AROMATASE) (EC 1.14.14.1) (CYPXIX) (ESTROGEN SYNTHETASE) (P-450AROM) - CARASSIUS AURATUS (GOLDFISH).
CPV1_ORYLA CYTOCHROME P450 19 (AROMATASE) (EC 1.14.14.1) (CYPXIX) (ESTROGEN SYNTHETASE) (P-450AROM) - ORYZIAS LATIPES (MEDAKA FISH).
O01997 T10B9.4 PROTEIN - CAENORHABDITIS ELEGANS.
O02641 PUTATIVE CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS.
O02646 HYPOTHETICAL 58.6 KD PROTEIN ZK938.1 IN CHROMOSOME II - CAENORHABDITIS ELEGANS.
O13254 CYTOCHROME P450 SCC (EC 1.14.14.1) - GALLUS GALLUS (CHICKEN).
O13490 CYTOCHROME P450 - MYROTHECIUM RORIDUM.
O16362 F44C8.1 PROTEIN - CAENORHABDITIS ELEGANS.
O16671 F41B5.3 PROTEIN - CAENORHABDITIS ELEGANS.
O17329 COSMID E03E2 - CAENORHABDITIS ELEGANS.
O17655 C41G6.1 PROTEIN - CAENORHABDITIS ELEGANS.
O17806 F14F7.2 PROTEIN - CAENORHABDITIS ELEGANS.
O17807 F14F7.3 PROTEIN - CAENORHABDITIS ELEGANS.
O22185 PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O22188 PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23154 CYTOCHROME P450-LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23155 CYTOCHROME P450 HOMOLOG - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23156 CYTOCHROME P450-LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23387 SIMILARITY TO CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23389 SIMILARITY TO CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O23391 SIMILAR TO CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O24315 CINNAMATE 4-HYDROXYLASE - PHASEOLUS VULGARIS (KIDNEY BEAN) (FRENCH BEAN).
O35728 CYTOCHROME P450 - MUS MUSCULUS (MOUSE).
O42430 CYP1A - LIMANDA LIMANDA (DAB).
O44658 B0213.14 PROTEIN - CAENORHABDITIS ELEGANS.
O44704 C45H4.2 PROTEIN - CAENORHABDITIS ELEGANS.
O45219 B0331.1 PROTEIN - CAENORHABDITIS ELEGANS.
O45605 H02I12.8 PROTEIN - CAENORHABDITIS ELEGANS.
O49342 PUTATIVE CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O53765 HYPOTHETICAL 50.7 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
O57315 BRAIN AROMATASE - CARASSIUS AURATUS (GOLDFISH).
O60634 CYTOCHROME P-450 - HOMO SAPIENS (HUMAN).
O61204 B0213.16 PROTEIN - CAENORHABDITIS ELEGANS.
O64853 PUTATIVE THROMBOXANE-A SYNTHASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O64989 STEROID 22-ALPHA-HYDROXYLASE - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O65438 CYTOCHROME P450 LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O65624 CYTOCHROME P450 - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O73852 CYTOCHROME P450 CHOLESTEROL SIDE CHAIN CLEAVAGE - ICTALURUS PUNCTATUS (CHANNEL CATFISH).
O74129 ALK3 - YARROWIA LIPOLYTICA (CANDIDA LIPOLYTICA).
O74131 ALK5 - YARROWIA LIPOLYTICA (CANDIDA LIPOLYTICA).
O74133 ALK7 - YARROWIA LIPOLYTICA (CANDIDA LIPOLYTICA).
O74292 CYTOCHROME P450 MONOOXYGENASE - FUSARIUM MONILIFORME (GIBBERELLA FUJIKUROI).
O76345 CYTOCHROME P450 - HOMARUS AMERICANUS (AMERICAN LOBSTER).
O76799 MICROSOMAL CYTOCHROME P450 - DROSOPHILA METTLERI (FRUIT FLY).
O76801 CYP9 CYTOCHROME P450 - DROSOPHILA METTLERI (FRUIT FLY).
O80823 PUTATIVE CYTOCHROME P450 (PUTATIVE CYTOCHROME P450, 3' PARTIAL) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O81725 CYTOCHROME P450 - LIKE PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O86330 HYPOTHETICAL 47.9 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
O88304 STEROID 21-HYDROXYLASE - MUS MUSCULUS (MOUSE).
P79716 CYTOCHROME P450 1A1 (EC 1.14.14.1) (CYPIA1) - DICENTRARCHUS LABRAX (EUROPEAN SEA BASS).
Q06884 CYTOCHROME P450 IIIA (EC 1.14.14.1) (STEROID INDUCIBLE) - Rattus norvegicus (Rat).
Q08078 CYTOCHROME P450 2C25 (EC 1.14.14.1) (CYPIIC25) (P450 HSM1) - MESOCRICETUS AURATUS (GOLDEN HAMSTER).
Q16757 CYTOCHROME P450 (NIFEDIPINE OXIDASE) (EC 1.14.14.1) - HOMO SAPIENS (HUMAN).
Q16802 FATTY ACID OMEGA-HYDROXYLASE (CYTOCHROME P450) (EC 1.14.14.1) - HOMO SAPIENS (HUMAN).
Q16843 THROMBOXANE SYNTHASE (EC 5.3.99.5) (THROMBOXANE-A SYNTHASE) (THROMBOXANE SYNTHETASE) - HOMO SAPIENS (HUMAN).
Q16872 CYTOCHROME P450 (EC 1.14.14.1) - HOMO SAPIENS (HUMAN).
Q21424 T19B10.1 PROTEIN - CAENORHABDITIS ELEGANS.
Q27465 SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS.
Q27466 C01F6.3 PROTEIN - CAENORHABDITIS ELEGANS.
Q27480 C44C10.2 PROTEIN - CAENORHABDITIS ELEGANS.
Q27482 SIMILAR TO CYTOCHROME P450 (EC 1.14.14.1) - CAENORHABDITIS ELEGANS.
Q27693 CYTOCHROME P450 (EC 1.14.14.1) - MUSCA DOMESTICA (HOUSE FLY).
Q27695 CYTOCHROME P450 - MUSCA DOMESTICA (HOUSE FLY).
Q42959 CYTOCHROME P450 (EC 1.14.14.1) - NICOTIANA TABACUM (COMMON TOBACCO).
Q43795 CYTOCHROME P450 (EC 1.14.14.1) - NICOTIANA TABACUM (COMMON TOBACCO).
Q64462 CYTOCHROME P450 4B1 (EC 1.14.14.1) (CYPIVB1) - MUS MUSCULUS (MOUSE).
Q64510 CYTOCHROME P450 (EC 1.14.14.1) - MUS MUSCULUS (MOUSE).
Q64529 CYTOCHROME P450 16A-MS1 (EC 1.14.14.1) - Mus spretus (Western wild mouse).
Q64590 CYTOCHROME P450 (EC 1.14.14.1) - RATTUS NORVEGICUS (RAT).
Q92039 CYTOCHROME P450 (EC 1.14.14.1) - CHAETODON CAPISTRATUS (FOUR-EYE BUTTERFLYFISH).
STCF_EMENI PROBABLE STERIGMATOCYSTIN BIOSYNTHESIS P450 MONOOXYGENASE STCF (EC 1.14.-.-) (CYTOCHROME P450 60A2) - EMERICELLA NIDULANS (ASPERGILLUS NIDULANS).
STCL_EMENI PROBABLE STERIGMATOCYSTIN BIOSYNTHESIS P450 MONOOXYGENASE STCL (EC 1.14.-.-) (CYTOCHROME P450 60B) - EMERICELLA NIDULANS (ASPERGILLUS NIDULANS).
STCS_EMENI PROBABLE STERIGMATOCYSTIN BIOSYNTHESIS P450 MONOOXYGENASE STCS (EC 1.14.-.-) (CYTOCHROME P450 59) - EMERICELLA NIDULANS (ASPERGILLUS NIDULANS).
TCMO_ARATH TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
TCMO_CICAR TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - CICER ARIETINUM (CHICKPEA) (GARBANZO).
TCMO_GLYEC TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - GLYCYRRHIZA ECHINATA (LICORICE).
TCMO_HELTU TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - HELIANTHUS TUBEROSUS (JERUSALEM ARTICHOKE).
TCMO_MEDSA TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - MEDICAGO SATIVA (ALFALFA).
TCMO_PETCR TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - PETROSELINUM CRISPUM (PARSLEY) (PETROSELINUM HORTENSE).
TCMO_PHAAU TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - PHASEOLUS AUREUS (MUNG BEAN) (VIGNA RADIATA).
TCMO_SOYBN TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - GLYCINE MAX (SOYBEAN).
TCMO_ZINEL TRANS-CINNAMATE 4-MONOOXYGENASE (EC 1.14.13.11) (CINNAMIC ACID 4-HYDROXYLASE) (CA4H) (C4H) (P450C4H) (CYTOCHROME P450 73) - ZINNIA ELEGANS.
YRV3_CAEEL PUTATIVE CYTOCHROME P450 T10B9.3 IN CHROMOSOME II (EC 1.14.-.-) - CAENORHABDITIS ELEGANS.
YRV7_CAEEL PUTATIVE CYTOCHROME P450 T10B9.7 IN CHROMOSOME II (EC 1.14.-.-) - CAENORHABDITIS ELEGANS.
Scan History
OWL27_1    2  120  NSINGLE    
SPTR37_9f 2 227 NSINGLE
Initial Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
PPIVFHWIPFVGSAVAYG CP51_SCHPO 33 33 -
PPLENGLIPYLGCALKFG CP70_CRIGR 32 32 -
PPLENGLIPYLGCALQFG CP70_HUMAN 32 32 -
PPLDLGSIPWLGHALEFG BOVPRSY 30 30 -
PPYIYSPIPFLGHAIAFG RNU17697 44 44 -
PPLDLGSIPWLGYALDFG JC2231 30 30 -
VPMVFYWIPWFGSAASYG CP51_CANTR 48 48 -

Motif 2 width=24
Element Seqn Id St Int Rpt
EFLRANQRKHGHVFTCKLMGKYVH CP70_CRIGR 54 4 -
EFLRANQRKHGHVFTCKLMGKYVH CP70_HUMAN 54 4 -
VFFRECRAKYGDVFTFVCMGRKMT CP51_SCHPO 55 4 -
EFLENAYEKYGPVFSFTMVGKTFT RNU17697 66 4 -
GFLTRMKEKHGDIFTVLVGGRHVT BOVPRSY 52 4 -
SFLTRMKEKHGDIFTILVGGRYVT JC2231 52 4 -
EFFEKCRLKYGDVFSFMLLGKVMT CP51_CANTR 70 4 -

Motif 3 width=27
Element Seqn Id St Int Rpt
ARALVLQLWATQGNMGPAAFWLLLFLL BOVPRSY 274 198 -
AGMLIGLLLAGQHTSSTTSAWMGFFLA RNU17697 285 195 -
ARALVLQLWATQGNMGPAAFWLLLFLL JC2231 274 198 -
AKTHLVVLWASQANTIPATFWSLFQMI CP70_HUMAN 276 198 -
AKTHLAILWASQANTIPATFWSLFQMI CP70_CRIGR 276 198 -
ANLLIGVLMGGQHTSASTSAWFLLHLA CP51_CANTR 298 204 -
AGMMIALLMAGQHTSAATIVWVLALLG CP51_SCHPO 279 200 -

Motif 4 width=17
Element Seqn Id St Int Rpt
LPVLDSIIKEALRLSSA CP70_CRIGR 343 40 -
TPVLDSVLSESLRLTAA JC2231 338 37 -
MPVLDSVLSESLRLTPA BOVPRSY 338 37 -
LNLLDRCIKETLRLRPP RNU17697 343 31 -
LPVLDSIIKESLRLSSA CP70_HUMAN 343 40 -
MPLLNYVIQETLRLHPP CP51_SCHPO 336 30 -
LPLVNNTIKETLRMHMP CP51_CANTR 359 34 -

Motif 5 width=15
Element Seqn Id St Int Rpt
YNIRKDDIIALYPQL CP70_CRIGR 379 19 -
FNLRRGDRLLLFPFL JC2231 375 20 -
FSLRRGDRLLLFPFL BOVPRSY 375 20 -
YTIPPGHQVCVSPTV RNU17697 376 16 -
IVIPANNYLLAAPGL CP51_SCHPO 371 18 -
YNIRKDDIIALYPQL CP70_HUMAN 379 19 -
YVIPKGHYVLVSAGY CP51_CANTR 394 18 -

Motif 6 width=19
Element Seqn Id St Int Rpt
QRDPEIYTDPEVFKYNRFL JC2231 392 2 -
QRLKDSWVERLDFNPDRYL RNU17697 392 1 -
QKDPEIYTDPEVFKYTRFL BOVPRSY 392 2 -
ATEEEYFTHATDFDPKRWN CP51_SCHPO 387 1 -
HTSDRWFEHPEHFNPRRWE CP51_CANTR 410 1 -
HLDPAIYPDPLTFKYDRYL CP70_CRIGR 395 1 -
HLDPEIYPDPLTFKYDRYL CP70_HUMAN 395 1 -

Motif 7 width=17
Element Seqn Id St Int Rpt
KRLKNYNMPWGAGHNHC JC2231 425 14 -
LKLKYYYMPFGSGATIC CP70_HUMAN 428 14 -
NKLKYFYMPFGSGATIC CP70_CRIGR 428 14 -
KGVSSPYLPFGGGRHRC CP51_CANTR 454 25 -
KGAASPYLPFGAGRHRC CP51_SCHPO 426 20 -
SGEKFAYVPFGAGRHRC RNU17697 416 5 -
KRLKNYSLPWGAGHNQC BOVPRSY 425 14 -

Motif 8 width=19
Element Seqn Id St Int Rpt
CIGENFAYVQIKTIWSTML RNU17697 432 -1 -
CIGEQFAYMHLSTIISKFV CP51_SCHPO 442 -1 -
CIGEQFAYVQLGTILTTYI CP51_CANTR 470 -1 -
CPGRLFAVQEIKQFLILML CP70_CRIGR 444 -1 -
CPGRLFAIHEIKQFLILML CP70_HUMAN 444 -1 -
CLGRSYAVNSIKQFVFLVL JC2231 441 -1 -
CLGKGYAVNSIKQFVFLVL BOVPRSY 441 -1 -
Final Motifs
Motif 1  width=18
Element Seqn Id St Int Rpt
PPLENGLIPYLGCALQFG CP70_HUMAN 32 32 -
PPLDNGLIPYLGCALKFG Q64505 32 32 -
PPLENGLIPYLGCALKFG CP70_RAT 32 32 -
PPLENGLIPYLGCALKFG CP70_CRIGR 32 32 -
PPLEKGWIPYLGCALQFG CP70_RABIT 32 32 -
PPLENGIIPYLGCALQFG CP70_PIG 32 32 -
PPLDLGSIPWLGHALEFG O35074 31 31 -
PPLDLGSIPWLGHALEFG Q62969 31 31 -
PPLDLGSIPWLGYALDFG PTGI_HUMAN 30 30 -
PPLDLGSIPWLGHALEFG PTGI_BOVIN 30 30 -
PPYIFSPIPFLGHAIAFG CP51_PIG 61 61 -
PPYIFSPIPFLGHAIAFG CP51_HUMAN 61 61 -
PPYIYSPIPFLGHAIAFG CP51_RAT 61 61 -
PPLDKGFVPWLGHSMAFR O88962 32 32 -
PPLDKGSIPWLGHAMTFR O02766 32 32 -
PPLVFYWIPWVGSAIPYG CP51_CANGA 57 57 -
PPVVFHFVPVIGSAIYYG CP51_USTMA 60 60 -
PPLVFYWIPWVGSAVVYG CP51_YEAST 56 56 -
APLVFYWIPWFGSAASYG CP51_CANAL 48 48 -
VPMVFYWIPWFGSAASYG CP51_CANTR 48 48 -
PPLIKGWLPYLGVVLNLR O75881 46 46 -
PPLIKGWLPYLGMALKFF Q60991 44 44 -
PPVVFHWIPFIGSTIAYG CP51_PENIT 42 42 -
PPIVFHWIPFVGSAVAYG CP51_SCHPO 33 33 -
PPVVFHWFPIIGSTISYG CP51_UNCNE 52 52 -
PPVLQAWPPFIGSLIRFM O22744 40 40 -

Motif 2 width=24
Element Seqn Id St Int Rpt
EFLRANQRKHGHVFTCKLMGKYVH CP70_HUMAN 54 4 -
EFLRAKQRKHGHVFTCKLMGKYVH Q64505 54 4 -
EFLRANQRKHGHVFTCKLMGKYVH CP70_RAT 54 4 -
EFLRANQRKHGHVFTCKLMGKYVH CP70_CRIGR 54 4 -
DFLRANQRKYGHVFTCKLMGKYVH CP70_RABIT 54 4 -
EFLRANQRKHGHIFTCQLMGNYVH CP70_PIG 54 4 -
SFLTRMKEKHGDIFTVLVGGRYVT O35074 53 4 -
SFLTRMKEKHGDIFTVLVGGRYVT Q62969 53 4 -
SFLTRMKEKHGDIFTILVGGRYVT PTGI_HUMAN 52 4 -
GFLTRMKEKHGDIFTVLVGGRHVT PTGI_BOVIN 52 4 -
EFLENAYEKYGPVFSFTMVGKTFT CP51_PIG 83 4 -
EFLENAYEKYGPVFSFTMVGKTFT CP51_HUMAN 83 4 -
EFLENAYEKYGPVFSFTMVGKTFT CP51_RAT 83 4 -
EFLKGMRAKHGDVFTVQLGGQYFT O88962 54 4 -
EFLKHMRSKHGDVFTVQLGGQYFT O02766 54 4 -
EFFEDCQKKYGDIFSFMLLGRIMT CP51_CANGA 79 4 -
KFFFECREKYGDVFTFVLLGRKIT CP51_USTMA 82 4 -
EFFEECQKKYGDIFSFVLLGRVMT CP51_YEAST 78 4 -
EFFESCRQKYGDVFSFMLLGKIMT CP51_CANAL 70 4 -
EFFEKCRLKYGDVFSFMLLGKVMT CP51_CANTR 70 4 -
RFMKTLQKQHGDTFTVLLGGKYIT O75881 68 4 -
TFLKTLQRQHGDTFTVFLVGKYIT Q60991 66 4 -
QFFFASRAKYGDIFTFILLGKKTT CP51_PENIT 64 4 -
VFFRECRAKYGDVFTFVCMGRKMT CP51_SCHPO 55 4 -
KFYFDCRAKYGDIFTFILLGKKVT CP51_UNCNE 74 4 -
VLLREEYPKLGSVFTVKLLHKNIT O22744 62 4 -

Motif 3 width=27
Element Seqn Id St Int Rpt
AKTHLVVLWASQANTIPATFWSLFQMI CP70_HUMAN 276 198 -
AKTHLVILWASQANTIPATFWSLFQMI Q64505 276 198 -
AKTHLAILWASQANTIPATFWSLFQMI CP70_RAT 276 198 -
AKTHLAILWASQANTIPATFWSLFQMI CP70_CRIGR 276 198 -
AKTHLAILWASQANTIPATFWSLFHMM CP70_RABIT 273 195 -
AKSLLAVLWASQANTIPATFWCLFQTI CP70_PIG 273 195 -
ARALVLQLWATQGNMGPTAFWLLLFLL O35074 275 198 -
ARALVLQLWATQGNMGPTAFWLLLFLL Q62969 275 198 -
ARALVLQLWATQGNMGPAAFWLLLFLL PTGI_HUMAN 274 198 -
ARALVLQLWATQGNMGPAAFWLLLFLL PTGI_BOVIN 274 198 -
AGMLIGLLLAGQHTSSTTSAWMGFFLA CP51_PIG 302 195 -
AGMLIGLLLAGQHTSSTTSAWMGFFLA CP51_HUMAN 302 195 -
AGMLIGLLLAGQHTSSTTSAWMGFFLA CP51_RAT 302 195 -
DKFNFMMLWASQGNTGPTCFWVLLFLL O88962 272 194 -
DKFNFMMLWASQGNTGPASFWALIYLL O02766 272 194 -
ANLLIGVLMGGQHTSAATSAWCLLHLA CP51_CANGA 306 203 -
AHMMIALLMAGQHTSSATSSWAFLRLA CP51_USTMA 316 210 -
ANLLIGVLMGGQHTSAATSAWILLHLA CP51_YEAST 305 203 -
ANLLIGILMGGQHTSASTSAWFLLHLG CP51_CANAL 298 204 -
ANLLIGVLMGGQHTSASTSAWFLLHLA CP51_CANTR 298 204 -
GAHHLGFLWASVANTIPTMFWAMYYLL O75881 283 191 -
GAHHLGFLWASLANTIPAMFWAMYYIL Q60991 281 191 -
AHMMITLLMAGQHSSSAISCWILLRLA CP51_PENIT 295 207 -
AGMMIALLMAGQHTSAATIVWVLALLG CP51_SCHPO 279 200 -
AHMMIALLMAGQHSSSSTSSWIMLWLA CP51_UNCNE 299 201 -
TGLLIAGLFAGQHTSSITATWTGAYLI O22744 264 178 -

Motif 4 width=17
Element Seqn Id St Int Rpt
LPVLDSIIKESLRLSSA CP70_HUMAN 343 40 -
LPVLDSIIKEALRLSSA Q64505 343 40 -
LPVLDSIIKEALRLSSA CP70_RAT 343 40 -
LPVLDSIIKEALRLSSA CP70_CRIGR 343 40 -
MPVLDSIIKESLRLSSA CP70_RABIT 340 40 -
MPVLDSIIKESLRLSSA CP70_PIG 340 40 -
MPVLDSVLNETLRLTAA O35074 339 37 -
MPVLDSVLNETLRLTAA Q62969 339 37 -
TPVLDSVLSESLRLTAA PTGI_HUMAN 338 37 -
MPVLDSVLSESLRLTAA PTGI_BOVIN 338 37 -
LNLLDRCIKETLRLRPP CP51_PIG 360 31 -
LNLLDRCIKETLRLRPP CP51_HUMAN 360 31 -
LNLLDRCIKETLRLRPP CP51_RAT 360 31 -
TPVLDSVMEESLRLCAT O88962 336 37 -
IPVLDSVMEETLRLGAA O02766 336 37 -
MPLLNQMIKETLRLHHP CP51_CANGA 364 31 -
VPLLDAVVKETLRLHPP CP51_USTMA 378 35 -
MPLLNQTIKETLRMHHP CP51_YEAST 363 31 -
LPSVNNTIKETLRMHMP CP51_CANAL 359 34 -
LPLVNNTIKETLRMHMP CP51_CANTR 359 34 -
LICLESSIFEALRLSSY O75881 349 39 -
LVCLESTILEVLRLCSY Q60991 347 39 -
LPLLRNVIKETLRLHSS CP51_PENIT 353 31 -
MPLLNYVIQETLRLHPP CP51_SCHPO 336 30 -
LQLHQNVLKEVLRLHAP CP51_UNCNE 359 33 -
MDFLFRSAKEALRLHPP O22744 322 31 -

Motif 5 width=15
Element Seqn Id St Int Rpt
YNIRKDDIIALYPQL CP70_HUMAN 379 19 -
YNIRKDDIIALYPQL Q64505 379 19 -
YNIRKDDMIALYPQL CP70_RAT 379 19 -
YNIRKDDIIALYPQL CP70_CRIGR 379 19 -
YNIRKDDIIALYPQL CP70_RABIT 376 19 -
YNIRKDDIIALYPQL CP70_PIG 376 19 -
FSLRRGDRLLLFPFL O35074 376 20 -
FSLRRGDRLLLFPFL Q62969 376 20 -
FNLRRGDRLLLFPFL PTGI_HUMAN 375 20 -
FSLRRGDRLLLFPFL PTGI_BOVIN 375 20 -
YTIPPGHQVCVSPTV CP51_PIG 393 16 -
YTIPPGHQVCVSPTV CP51_HUMAN 393 16 -
YTIPPGHQVCVSPTV CP51_RAT 393 16 -
YQIRRGDKVALFPYL O88962 373 20 -
CLLRQGDIVTLFPYL O02766 373 20 -
YVVPRDYHVLVSPGY CP51_CANGA 399 18 -
YVIPKGHYIMAAPGV CP51_USTMA 426 31 -
YVIPAGYHVLVSPGY CP51_YEAST 398 18 -
YIVPKGHYVLVSPGY CP51_CANAL 394 18 -
YVIPKGHYVLVSAGY CP51_CANTR 394 18 -
YCVRKGDLVAIFPPV O75881 385 19 -
FSLRKGDFVALFPPL Q60991 383 19 -
FVVPPSHTLLSSPGV CP51_PENIT 388 18 -
IVIPANNYLLAAPGL CP51_SCHPO 371 18 -
YVIPTSHVLISSPGC CP51_UNCNE 394 18 -
YEIPKGHIVATSPAF O22744 360 21 -

Motif 6 width=19
Element Seqn Id St Int Rpt
HLDPEIYPDPLTFKYDRYL CP70_HUMAN 395 1 -
HLDPEIYPDPLTFKYDRYL Q64505 395 1 -
HLDPEIYPDPLTFKYDRYL CP70_RAT 395 1 -
HLDPAIYPDPLTFKYDRYL CP70_CRIGR 395 1 -
HLDPEIYPDPMTFKYDRYL CP70_RABIT 392 1 -
HLDPEIYPDPLTFKYDRYL CP70_PIG 392 1 -
QKDPEIYTEPEVFKYNRFL O35074 393 2 -
QKDPEIYTEPEVFKYNRFL Q62969 393 2 -
QRDPEIYTDPEVFKYNRFL PTGI_HUMAN 392 2 -
QKDPEIYTDPEVFKYNRFL PTGI_BOVIN 392 2 -
QRLKDSWVERLDFNPDRYL CP51_PIG 409 1 -
QRLKDSWVERLDFNPDRYL CP51_HUMAN 409 1 -
QRLKDSWVERLDFNPDRYL CP51_RAT 409 1 -
HMDPDIHPEPTAFKYDRFL O88962 390 2 -
HMDPDIHPEPTTFKYDRFL O02766 390 2 -
HLQEEFFPKPNEFNIHRWD CP51_CANGA 415 1 -
QVDPQIWKSSDQFDPHRWL CP51_USTMA 442 1 -
HLRDEYFPNAHQFNIHRWN CP51_YEAST 414 1 -
HTSERYFDNPEDFDPTRWD CP51_CANAL 410 1 -
HTSDRWFEHPEHFNPRRWE CP51_CANTR 410 1 -
HGDPEIFEAPEEFRYDRFI O75881 401 1 -
HNDPEIFDAPKEFRFDRFI Q60991 399 1 -
ARDERHFRDPLRWDPHRWE CP51_PENIT 404 1 -
ATEEEYFTHATDFDPKRWN CP51_SCHPO 387 1 -
SQDATFFPDPLKWDPHRWD CP51_UNCNE 410 1 -
NRLPHVYKDPENFDPDRFS O22744 376 1 -

Motif 7 width=17
Element Seqn Id St Int Rpt
LKLKYYYMPFGSGATIC CP70_HUMAN 428 14 -
NKLKYFYMPFGSGATIC Q64505 428 14 -
NKLKCFYMPFGSGATIC CP70_RAT 428 14 -
NKLKYFYMPFGSGATIC CP70_CRIGR 428 14 -
LKLKYYYMPFGSGATIC CP70_RABIT 425 14 -
LKLKYYYMPFGSGATIC CP70_PIG 425 14 -
KRLKNYNMPWGAGHNQC O35074 426 14 -
KRLKNYNMPWGAGHNQC Q62969 426 14 -
KRLKNYNMPWGAGHNHC PTGI_HUMAN 425 14 -
KRLKNYSLPWGAGHNQC PTGI_BOVIN 425 14 -
SGEKFAYVPFGAGRHRC CP51_PIG 433 5 -
SGEKFAYVPFGAGRHRC CP51_HUMAN 433 5 -
SGEKFAYVPFGAGRHRC CP51_RAT 433 5 -
KKIHHYSMPWGSGVSKC O88962 423 14 -
QKIHHYTMPWGSGVSIC O02766 423 14 -
KGVSSPYLPFGGGRHRC CP51_CANGA 456 22 -
TGANSPYLPFGAGRHRC CP51_USTMA 485 24 -
KGVSSPYLPFGGGRHRC CP51_YEAST 454 21 -
KGVSSPYLPFGGGRHRC CP51_CANAL 454 25 -
KGVSSPYLPFGGGRHRC CP51_CANTR 454 25 -
KKLKCYLMPFGTGTSKC O75881 433 13 -
KRLKTYVMPFGLGTSKC Q60991 431 13 -
KGTRSPYLPFGAGRHRC CP51_PENIT 443 20 -
KGAASPYLPFGAGRHRC CP51_SCHPO 426 20 -
TGASSPYLPFGAGRHRC CP51_UNCNE 453 24 -
AAGSCSYISLGAGRHEC O22744 402 7 -

Motif 8 width=19
Element Seqn Id St Int Rpt
CPGRLFAIHEIKQFLILML CP70_HUMAN 444 -1 -
CPGRLFAVQEIKQFLILML Q64505 444 -1 -
CPGRLFAVQEIKQFLILML CP70_RAT 444 -1 -
CPGRLFAVQEIKQFLILML CP70_CRIGR 444 -1 -
CPGRLFAIQEIKQFLILML CP70_RABIT 441 -1 -
CPGRLFAVQEIKQFLILML CP70_PIG 441 -1 -
CLGKSYAINSIKQFVVLLL O35074 442 -1 -
CLGKSYAINSIKQFVVLLL Q62969 442 -1 -
CLGRSYAVNSIKQFVFLVL PTGI_HUMAN 441 -1 -
CLGKGYAVNSIKQFVFLVL PTGI_BOVIN 441 -1 -
CIGENFAYVQIKTIWSTML CP51_PIG 449 -1 -
CIGENFAYVQIKTIWSTML CP51_HUMAN 449 -1 -
CIGENFAYVQIKTIWSTML CP51_RAT 449 -1 -
CPGRFFALSEMKTFVLLMI O88962 439 -1 -
CPGRFFALSEMKLFVLLMV O02766 439 -1 -
CIGELFAYCQLGVLMSIFI CP51_CANGA 472 -1 -
CIGEQFAYLQIGVILATFV CP51_USTMA 501 -1 -
CIGEHFAYCQLGVLMSIFI CP51_YEAST 470 -1 -
CIGEQFAYVQLGTILTTFV CP51_CANAL 470 -1 -
CIGEQFAYVQLGTILTTYI CP51_CANTR 470 -1 -
CPGRFFALMEIKQLLVILL O75881 449 -1 -
CPGRYFAVNEMKLLLIELL Q60991 447 -1 -
CIGEKFAYLNLEVIVATLV CP51_PENIT 459 -1 -
CIGEQFAYMHLSTIISKFV CP51_SCHPO 442 -1 -
CIGEQFATLQLVTIMATMV CP51_UNCNE 469 -1 -
CPGGSFAFLQIKAVWCHLL O22744 418 -1 -