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PR00326

Identifier
GTP1OBG  [View Relations]  [View Alignment]  
Accession
PR00326
No. of Motifs
4
Creation Date
24-OCT-1994  (UPDATE 07-JUN-1999)
Title
GTP1/OBG GTP-binding protein family signature
Database References

PROSITE; PS00905 GTP1_OBG; PS00017 ATP_GTP_A
PFAM; PF01018 GTP1_OBG
INTERPRO; IPR000765
Literature References
1. SAZUKA, T., TOMOOKA, Y., IKAWA, Y., NODA, M. AND KUMAR, S.
DRG: a novel developmentally regulated GTP-binding protein.
BIOCHEM.BIOPHYS.RES.COMMUN. 189 363-370 (1992).
 
2. HUDSON, J.D. AND YOUNG, P.G.
Sequence of the Schizosaccharomyces pombe gtp1 gene and identification of
a novel family of putative GTP-binding proteins.
GENE 125 191-193 (1993).
 
3. TRACH, K. AND HOCH, J.A.
The Bacillus subtilis spo0B stage 0 sporulation operon includes an essential
GTP-binding protein.
J.BACTERIOL. 171 1362-1371 (1989).

Documentation
Several proteins have recently been shown to contain the 5 structural
motifs characteristic of GTP-binding proteins [1]: these include murine
DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from
Bacillus subtilis; and several others. Although the proteins contain GTP-
binding motifs and are similar to each other, they do not share sequence
similarity to other GTP-binding proteins, and have thus been classed as a
novel group - the GTP1/OBG family [2,3]. As yet, the functions of these 
proteins is uncertain, but they have been shown to be important in
development and normal cell metabolism [2,3].
 
GTP1OBG is a 4-element fingerprint that provides a signature for the
GTP1/OBG family of GTP-binding proteins. The fingerprint was derived from
an initial alignment of 6 sequences: motifs 1-3 were drawn from conserved
regions thought to form the GTP-binding pocket, and correspond to the regions
encoded by PROSITE patterns ATP_GTP_A (PS00017) (binding site motif A, or
the so-called P-loop), and GTP1_OBG (PS00905) (binding site motif B). Two
iterations on OWL24_0 were required to reach convergence, at which point a
true set comprising 7 sequences was identified. A single partial match was
also found, YSCH99867, which is similar to the GTP1/OBG family but shows
marked differences in the region surrounding the third GTP-binding site.
 
An update on SPTR37_9f identified a true set of 58 sequences, and 6
partial matches.
Summary Information
  58 codes involving  4 elements
1 codes involving 3 elements
5 codes involving 2 elements
Composite Feature Index
458585858
31101
25311
1234
True Positives
128U_DROME    DRG2_HUMAN    DRG_MOUSE     DRG_XENLA     
GTP1_SCHPO O04174 O13998 O25293
O27559 O27658 O28136 O28907
O30861 O45691 O51251 O51722
O53459 O57346 O58261 O59329
O66865 O67849 O83161 O83724
O84094 O84423 OBG_BACSU P71909
P72931 P73886 P78786 P95722
P95758 P96085 Q18219 Q18220
Q58722 Q58728 Y024_MYCGE Y024_MYCPN
Y303_HELPY Y384_MYCGE Y384_MYCPN YAD6_YEAST
YBN5_YEAST YCHF_CAEEL YCHF_ECOLI YCHF_HAEIN
YEAD_SCHPO YG3Y_YEAST YG4I_YEAST YHBZ_ECOLI
YHBZ_HAEIN YHW8_YEAST YKK3_CAEEL YLF2_YEAST
YRB1_HALCU YYAF_BACSU
True Positive Partials
Codes involving 3 elements
O22445
Codes involving 2 elements
O26946 O59046 O87407 P74120
Q58803
Sequence Titles
128U_DROME  GTP-BINDING PROTEIN 128UP - DROSOPHILA MELANOGASTER (FRUIT FLY). 
DRG2_HUMAN DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN DRG2 - HOMO SAPIENS (HUMAN).
DRG_MOUSE DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN DRG (NEDD3 PROTEIN) - MUS MUSCULUS (MOUSE).
DRG_XENLA DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN DRG (XDRG) - XENOPUS LAEVIS (AFRICAN CLAWED FROG).
GTP1_SCHPO GTP-BINDING PROTEIN 1 - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O04174 GTP-BINDING PROTEIN - ARABIDOPSIS THALIANA (MOUSE-EAR CRESS).
O13998 HYPOTHETICAL 44.3 KD PROTEIN C27E2.03C IN CHROMOSOME I - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
O25293 GTP-BINDING PROTEIN (GTP1) - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
O27559 GTP-BINDING PROTEIN - METHANOBACTERIUM THERMOAUTOTROPHICUM.
O27658 GTP-BINDING PROTEIN, GTP1/OBG FAMILY - METHANOBACTERIUM THERMOAUTOTROPHICUM.
O28136 GTP-BINDING PROTEIN - ARCHAEOGLOBUS FULGIDUS.
O28907 GTP-BINDING PROTEIN - ARCHAEOGLOBUS FULGIDUS.
O30861 GTP-BINDING PROTEIN - CAULOBACTER CRESCENTUS.
O45691 M01E5.2 PROTEIN - CAENORHABDITIS ELEGANS.
O51251 CONSERVED HYPOTHETICAL PROTEIN - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O51722 GTP-BINDING PROTEIN (OBG) - BORRELIA BURGDORFERI (LYME DISEASE SPIROCHETE).
O53459 HYPOTHETICAL 38.1 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
O57346 GTP-BINDING PROTEIN - ONCORHYNCHUS TSCHAWYTSCHA (CHINOOK SALMON) (KING SALMON).
O58261 397AA LONG HYPOTHETICAL GTP-BINDING PROTEIN - PYROCOCCUS HORIKOSHII.
O59329 387AA LONG HYPOTHETICAL DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN - PYROCOCCUS HORIKOSHII.
O66865 HYPOTHETICAL 41.3 KD PROTEIN - AQUIFEX AEOLICUS.
O67849 GTP-BINDING PROTEIN - AQUIFEX AEOLICUS.
O83161 CONSERVED HYPOTHETICAL GTP-BINDING PROTEIN - TREPONEMA PALLIDUM.
O83724 GTP-BINDING PROTEIN (OBG) - TREPONEMA PALLIDUM.
O84094 GTP BINDING PROTEIN - CHLAMYDIA TRACHOMATIS.
O84423 GTP BINDING PROTEIN - CHLAMYDIA TRACHOMATIS.
OBG_BACSU SPO0B-ASSOCIATED GTP-BINDING PROTEIN - BACILLUS SUBTILIS.
P71909 HYPOTHETICAL 50.4 KD PROTEIN - MYCOBACTERIUM TUBERCULOSIS.
P72931 GTP-BINDING PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P73886 HYPOTHETICAL 39.3 KD PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
P78786 FISSION YEAST - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
P95722 OBG - STREPTOMYCES COELICOLOR.
P95758 OBG - STREPTOMYCES GRISEUS.
P96085 GTP-BINDING PROTEIN - THERMOPLASMA ACIDOPHILUM.
Q18219 COSMID C26E6 - CAENORHABDITIS ELEGANS.
Q18220 COSMID C26E6 - CAENORHABDITIS ELEGANS.
Q58722 HYPOTHETICAL GTP-BINDING PROTEIN MJ1326 - METHANOCOCCUS JANNASCHII.
Q58728 HYPOTHETICAL GTP-BINDING PROTEIN MJ1332 - METHANOCOCCUS JANNASCHII.
Y024_MYCGE PROBABLE GTP-BINDING PROTEIN MG024 - MYCOPLASMA GENITALIUM.
Y024_MYCPN PROBABLE GTP-BINDING PROTEIN MG024 HOMOLOG - MYCOPLASMA PNEUMONIAE.
Y303_HELPY PROBABLE GTP-BINDING PROTEIN HP0303 - HELICOBACTER PYLORI (CAMPYLOBACTER PYLORI).
Y384_MYCGE PROBABLE GTP-BINDING PROTEIN MG384 - MYCOPLASMA GENITALIUM.
Y384_MYCPN PROBABLE GTP-BINDING PROTEIN MG384 HOMOLOG - MYCOPLASMA PNEUMONIAE.
YAD6_YEAST HYPOTHETICAL 40.7 KD PROTEIN IN PYK1-SNC1 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YBN5_YEAST HYPOTHETICAL 44.2 KD GTP-BINDING PROTEIN IN SCO2-MRF1 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YCHF_CAEEL PUTATIVE GTP-BINDING PROTEIN W08E3.3 - CAENORHABDITIS ELEGANS.
YCHF_ECOLI PROBABLE GTP-BINDING PROTEIN IN TREA-PTH INTERGENIC REGION (ORF-3) - ESCHERICHIA COLI.
YCHF_HAEIN PROBABLE GTP-BINDING PROTEIN HI0393 - HAEMOPHILUS INFLUENZAE.
YEAD_SCHPO HYPOTHETICAL 45.4 KD GTP-BINDING PROTEIN C2E11.13C IN CHROMOSOME I - SCHIZOSACCHAROMYCES POMBE (FISSION YEAST).
YG3Y_YEAST HYPOTHETICAL 41.0 KD PROTEIN IN YIP1-CBP4 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YG4I_YEAST HYPOTHETICAL 45.2 KD GTP-BINDING PROTEIN IN TRX1-ZPR1 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YHBZ_ECOLI HYPOTHETICAL 43.3 KD GTP-BINDING PROTEIN IN DACB-RPMA INTERGENIC REGION - ESCHERICHIA COLI.
YHBZ_HAEIN HYPOTHETICAL 43.4 KD GTP-BINDING PROTEIN HI0877 - HAEMOPHILUS INFLUENZAE.
YHW8_YEAST HYPOTHETICAL 55.5 KD GTP-BINDING PROTEIN IN CDC23-DBP8 INTERGENIC REGION - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YKK3_CAEEL HYPOTHETICAL 64.3 KD GTP-BINDING PROTEIN C02F5.3 IN CHROMOSOME III - CAENORHABDITIS ELEGANS.
YLF2_YEAST PUTATIVE GTP-BINDING PROTEIN YLF2 - SACCHAROMYCES CEREVISIAE (BAKER'S YEAST).
YRB1_HALCU HYPOTHETICAL 40 KD GTP-BINDING PROTEIN IN RIBOSOMAL PROTEIN GENE CLUSTER 5'REGION - HALOBACTERIUM CUTIRUBRUM.
YYAF_BACSU HYPOTHETICAL 40.1 KD GTP-BINDING PROTEIN IN RPSF-SPO0J INTERGENIC REGION - BACILLUS SUBTILIS.

O22445 DEVELOPMENTALLY REGULATED GTP BINDING PROTEIN - PISUM SATIVUM (GARDEN PEA).

O26946 GTP-BINDING PROTEIN, GTP1/OBG FAMILY - METHANOBACTERIUM THERMOAUTOTROPHICUM.
O59046 357AA LONG HYPOTHETICAL PROTEIN - PYROCOCCUS HORIKOSHII.
O87407 ESSENTIAL GC PROTEIN - NEISSERIA GONORRHOEAE.
P74120 HYPOTHETICAL 50.8 KD PROTEIN - SYNECHOCYSTIS SP. (STRAIN PCC 6803).
Q58803 HYPOTHETICAL PROTEIN MJ1408 - METHANOCOCCUS JANNASCHII.
Scan History
OWL24_0    2  100  NSINGLE    
OWL28_1 1 100 NSINGLE
SPTR37_9f 2 91 NSINGLE
Initial Motifs
Motif 1  width=21
Element Seqn Id St Int Rpt
VGLVGFPSVGKSTLLSVVSSA OBG_BACSU 161 161 -
VGIVGFPNSGKSTLISKLSNA Y384_MYCGE 162 162 -
VGMLGLPNAGKSTFIRAVSAA YHBZ_HAEIN 162 162 -
VGMLGMPNAGKSTFIRAVSAA YHBZ_ECOLI 162 162 -
IGFVGFPSVGKSTLLSNLAGV DRG_MOUSE 67 67 -
VGFVGFPSVGKSTLLSNLAGV 128U_DROME 67 67 -
VAMVGFPSVGKSTLLSSMTST YKK3_CAEEL 65 65 -
VAFIGFPSVGKSTLLSAITKT GTP1_SCHPO 65 65 -
VALVGFPSVGKSSLINAMTNA YRB1_HALCU 64 64 -
LGLIGLPNAGKSTILNKISNA YHW8_YEAST 342 342 -

Motif 2 width=19
Element Seqn Id St Int Rpt
KPKIADYHFTTLVPNLGMV OBG_BACSU 182 0 -
KPKIANYRFTTLIPVLGVV Y384_MYCGE 183 0 -
KPKVADYPFTTLVPSLGVV YHBZ_HAEIN 183 0 -
KPKVADYPFTTLVPSLGVV YHBZ_ECOLI 183 0 -
YSEVAAYEFTTLTTVPGVI DRG_MOUSE 88 0 -
YSEVAAYEFTTLTTVPGCI 128U_DROME 88 0 -
HSEAAGYEFTTLTCIPGVI YKK3_CAEEL 86 0 -
KSATASYEFTTLTAIPGVL GTP1_SCHPO 86 0 -
DSEVGAYEFTTLNVNPGML YRB1_HALCU 85 0 -
KPKIGHWQFTTLSPTIGTV YHW8_YEAST 363 0 -

Motif 3 width=16
Element Seqn Id St Int Rpt
MADLPGLIEGAHQGVG OBG_BACSU 210 9 -
FADIPGLIENASEGSG Y384_MYCGE 210 8 -
VADIPGLIEGAADGAG YHBZ_HAEIN 211 9 -
VADIPGLIEGAAEGAG YHBZ_ECOLI 211 9 -
LLDLPGIIEGAKDGKG DRG_MOUSE 115 8 -
LLDLPGIIEGAKDGKG 128U_DROME 115 8 -
LLDLPGIIEGASQGKG YKK3_CAEEL 113 8 -
MLDLPGIIEGASQGRG GTP1_SCHPO 113 8 -
LLDVPGLIEGAAGGRG YRB1_HALCU 112 8 -
VADIPGIIQGASLDKG YHW8_YEAST 392 10 -

Motif 4 width=19
Element Seqn Id St Int Rpt
GHQFLRHIERTRVIVHVID OBG_BACSU 227 1 -
GHDFLRHIERCEILIHLIS Y384_MYCGE 227 1 -
GIRFLKHLERCRVLIHLVD YHBZ_HAEIN 228 1 -
GIRFLKHLERCRVLLHLID YHBZ_ECOLI 228 1 -
GRQVIAVARTCNLILIVLD DRG_MOUSE 132 1 -
GRQVIAVARTCNLIFMVLD 128U_DROME 132 1 -
GRQVISVAKTADLILMMLD YKK3_CAEEL 130 1 -
GRQAVSAARTADLILMVFG GTP1_SCHPO 129 0 -
GKEILSVIRGADLVIFVLS YRB1_HALCU 129 1 -
GLEFLRHIERSNGWVFVLD YHW8_YEAST 409 1 -
Final Motifs
Motif 1  width=21
Element Seqn Id St Int Rpt
CGIVGLPNVGKSTLFNALTKA YCHF_HAEIN 4 4 -
LGIVGLPNVGKSTLFNALTKT O66865 5 5 -
AGIVGLPNVGKSTLFSAITNL Y024_MYCPN 4 4 -
AGIVGLPNVGKSTLFSAITNL Y024_MYCGE 4 4 -
LGIVGLPNVGKSTLFNALTRN O53459 5 5 -
VGIIGLPNAGKSTLIAALSAA P72931 162 162 -
VGLVGFPSAGKSSLVSAISAA P71909 162 162 -
AGIVGLPNVGKSTLFNAITQA YYAF_BACSU 5 5 -
AGIVGLPNVGKSTLFNALVAN P73886 4 4 -
AGIVGLPNVGKSTLFSSLTSS O51251 5 5 -
IGLVGFPNAGKSTLISTISNA Y303_HELPY 159 159 -
CGIVGLPNVGKSTLFNALTKA YCHF_ECOLI 4 4 -
VGLVGFPNAGKSTLLSRLTRA O67849 163 163 -
VGLVGFPSVGKSTLLSVVSSA OBG_BACSU 161 161 -
VALVGYPSAGKSSLISVLSAA P95758 162 162 -
VALVGYPSAGKSSLISVLSAA P95722 162 162 -
VGLVGLPNAGKSTFLAAASAA O30861 162 162 -
CGIIGLPNVGKSTIFSALTAN O83161 5 5 -
VGIVGFPNTGKSTLISKLSNA Y384_MYCPN 162 162 -
VGIVGFPNSGKSTLISKLSNA Y384_MYCGE 162 162 -
VGMLGLPNAGKSTFIRAVSAA YHBZ_HAEIN 162 162 -
VGIVGLPNVGKSSTFNALTKT O25293 5 5 -
CGIVGLPNVGKSGLFNALTGA O84094 8 8 -
IGVVGKPNVGKSTFFSAATLV O58261 3 3 -
VGMLGMPNAGKSTFIRAVSAA YHBZ_ECOLI 162 162 -
IGLVGFPNAGKSTLFNTLART O84423 161 161 -
IGFVGFPSVGKSTLLSNLAGV DRG_XENLA 67 67 -
IGFVGFPSVGKSTLLSNLAGV DRG_MOUSE 67 67 -
IGLVGLPNAGKSSLLNRITSA O51722 163 163 -
VVLIGFPSVGKSTLLNELTSA O27658 80 80 -
IGLVGKPNVGKSTMFNALTEK Q58728 4 4 -
VGFVGFPSVGKSTLLSNLAGV 128U_DROME 67 67 -
VALIGFPSVGKSTLLTMLTGT O04174 65 65 -
AVLIGYPSVGKSTLLNKLTGA O28136 66 66 -
VAMVGFPSVGKSTLLSSMTST YKK3_CAEEL 65 65 -
VGFIGFPSVGKSTLMTQLTGT P78786 66 66 -
IGIAGKPNAGKSTFFKAATLA O28907 4 4 -
VALIGFPSVGKSTFLSLMTAT O57346 65 65 -
AAFVGFPSVGKSTLLNKLTNA Q58722 87 87 -
VAFIGFPSVGKSTLLSAITKT GTP1_SCHPO 65 65 -
VGFVGFPSVGKSTLLSKLTGT YAD6_YEAST 68 68 -
VVLIGYPSVGKSSLLGKITTT YG3Y_YEAST 66 66 -
VALVGFPSVGKSSLINAMTNA YRB1_HALCU 64 64 -
VALIGFPSVGKSTFLSLMTST DRG2_HUMAN 65 65 -
AGLVGFPNAGKSSLLRAISRA O45691 191 191 -
AGIVGLANVGKSTFFQAITRC YBN5_YEAST 23 23 -
IVLVGLPNVGKSELLRALTGV O59329 84 84 -
VALVGFPNVGKSSLLNRLTNS P96085 63 63 -
IGLLGFPNAGKSTLLKALVPE Q18219 164 164 -
IGLLGFPNAGKSTLLKALVPE Q18220 164 164 -
IGIVGKPSSGKSTTLNSLTDA YG4I_YEAST 7 7 -
TGIVGMPNVGKSTFFRAITKS O13998 23 23 -
VGFVGLPNAGKSSLLNFFTHA O83724 164 164 -
IAVTGKPNVGKSSFFNAATLS O27559 7 7 -
VGILGLPNVGKSTFFNVLTKS YCHF_CAEEL 24 24 -
LGLIGLPNAGKSTILNKISNA YHW8_YEAST 342 342 -
SGIVGLANVGKSTFFQAITNS YLF2_YEAST 19 19 -
IGIVGMPNIGKSTLFQILTKT YEAD_SCHPO 48 48 -

Motif 2 width=19
Element Seqn Id St Int Rpt
GIEAANYPFCTIEPNTGVV YCHF_HAEIN 25 0 -
KAQAANYPFCTIEPNVGVV O66865 27 1 -
QVEIANYPFATIEPNAGIV Y024_MYCPN 25 0 -
QVEIANYPFATIEPNTGIV Y024_MYCGE 25 0 -
NVVAANYPFATIEPNEGVV O53459 26 0 -
RPKIADYPFTTLVPNLGVV P72931 183 0 -
KPKIADYPFTTLVPNLGVV P71909 183 0 -
GAESANYPFCTIDPNVGIV YYAF_BACSU 26 0 -
KAEAANFPFCTIEPNVGVV P73886 26 1 -
NVEIANYPFCTIEPNIGIV O51251 26 0 -
KPKIANYEFTTLVPNLGVV Y303_HELPY 180 0 -
GIEAANFPFCTIEPNTGVV YCHF_ECOLI 25 0 -
KPKIADYPFTTLSPNLGVM O67849 184 0 -
KPKIADYHFTTLVPNLGMV OBG_BACSU 182 0 -
KPKIADYPFTTLVPNLGVV P95758 183 0 -
KPKIADYPFTTLVPNLGVV P95722 183 0 -
KPKIADYPFTTLTPNLGVV O30861 183 0 -
VVEAANYPFCTIEPNVGMV O83161 26 0 -
KPKIANYRFTTLVPVLGVV Y384_MYCPN 183 0 -
KPKIANYRFTTLIPVLGVV Y384_MYCGE 183 0 -
KPKVADYPFTTLVPSLGVV YHBZ_HAEIN 183 0 -
NAQSANYPFCTIEPNKAIV O25293 27 1 -
QVASCNYPFCTIDPNVGIV O84094 29 0 -
DVEIANYPFTTIEANVGVT O58261 24 0 -
KPKVADYPFTTLVPSLGVV YHBZ_ECOLI 183 0 -
EVKVGAYPFTTLHPSLGLV O84423 182 0 -
YSEVAAYEFTTLTTVPGVV DRG_XENLA 88 0 -
YSEVAAYEFTTLTTVPGVI DRG_MOUSE 88 0 -
KSRVANYPFTTKIPHLGML O51722 184 0 -
ESKVGDYQFTTLEIVPGVM O27658 101 0 -
PAEIGNYPFTTIQPNKGIA Q58728 25 0 -
YSEVAAYEFTTLTTVPGCI 128U_DROME 88 0 -
HSEAASYEFTTLTCIPGVI O04174 86 0 -
KSEVADYDFTTLKPVPGIL O28136 87 0 -
HSEAAGYEFTTLTCIPGVI YKK3_CAEEL 86 0 -
RSEAAAYEFTTLTTVPGVL P78786 87 0 -
DAEIANYPFTTIKPNVGIG O28907 25 0 -
ASEAASYEFTTLTCIPGVI O57346 86 0 -
KSEVGAYAFTTLTIVPGIL Q58722 108 0 -
KSATASYEFTTLTAIPGVL GTP1_SCHPO 86 0 -
ESEAAEYEFTTLVTVPGVI YAD6_YEAST 89 0 -
KSEIAHYAFTTLTSVPGVL YG3Y_YEAST 87 0 -
DSEVGAYEFTTLNVNPGML YRB1_HALCU 85 0 -
ASEAASYEFTTLTCIPGVI DRG2_HUMAN 86 0 -
KPKVASYPFTTLHPHIGVV O45691 212 0 -
LGNPANYPFATIDPEEARV YBN5_YEAST 45 1 -
DVESADYPFTTTEPVPAMM O59329 105 0 -
ESEIGDYAFTTLQPIPGIL P96085 84 0 -
SVKIADYAFTTVNPQVAFF Q18219 186 1 -
SVKIADYAFTTVNPQVAFF Q18220 186 1 -
GAAVGAFPFTTIEPNQATG YG4I_YEAST 28 0 -
LGNPANYPYATIDPEEAKV O13998 45 1 -
RSRVAPYPFTTRIPYLGVL O83724 185 0 -
EAEVASYPFTTIDANHAVA O27559 28 0 -
EAQAENFPFCTIDPNESRV YCHF_CAEEL 45 0 -
KPKIGHWQFTTLSPTIGTV YHW8_YEAST 363 0 -
LGNPANYPFATIDAECAKV YLF2_YEAST 41 1 -
LGNPANYPFATIDPVHAKA YEAD_SCHPO 70 1 -

Motif 3 width=16
Element Seqn Id St Int Rpt
FVDIAGLVAGASKGEG YCHF_HAEIN 69 25 -
FVDIAGLVKGASKGEG O66865 71 25 -
FVDIAGLVKGASKGEG Y024_MYCPN 69 25 -
FVDIAGLVKGASQGQG Y024_MYCGE 69 25 -
FVDIAGLVKGASEGAG O53459 70 25 -
FADIPGLIEGAAAGIG P72931 211 9 -
VADVPGLIPGASRGRG P71909 210 8 -
FTDIAGIVKGASKGEG YYAF_BACSU 70 25 -
FVDIAGLVAGASKGEG P73886 70 25 -
FVDIAGLVKGASTGEG O51251 70 25 -
MADIPGIIEGASEGKG Y303_HELPY 208 9 -
FVDIAGLVKGASKGEG YCHF_ECOLI 69 25 -
IADIPGLIEDAHKGAG O67849 212 9 -
MADLPGLIEGAHQGVG OBG_BACSU 210 9 -
IADVPGLIPGASQGKG P95758 210 8 -
VADVPGLIPGASQGKG P95722 210 8 -
LADIPGLIEGASEGAG O30861 211 9 -
CVDIAGLVKGASQGEG O83161 70 25 -
FADIPGLIENASEGSG Y384_MYCPN 210 8 -
FADIPGLIENASEGSG Y384_MYCGE 210 8 -
VADIPGLIEGAADGAG YHBZ_HAEIN 211 9 -
FVDIAGLIKGASKGEG O25293 71 25 -
FVDIAGLVKGAASGAG O84094 73 25 -
MVDVAGLVPGAHEGRG O58261 75 32 -
VADIPGLIEGAAEGAG YHBZ_ECOLI 211 9 -
MADIPGIIEGASQNRG O84423 213 12 -
LLDLPGIIEGAKDGKG DRG_XENLA 115 8 -
LLDLPGIIEGAKDGKG DRG_MOUSE 115 8 -
IADIPGIIKGASFGVG O51722 211 8 -
IFDIPGIITGASRGRG O27658 128 8 -
VIDVAGLVPGAHEGRG Q58728 76 32 -
LLDLPGIIEGAKDGKG 128U_DROME 115 8 -
LLDLPGIIEGASEGKG O04174 113 8 -
IIDVPGIIEGAASGRG O28136 114 8 -
LLDLPGIIEGASQGKG YKK3_CAEEL 113 8 -
ILDLPGIIEGAKDGRG P78786 114 8 -
LIDVAGLVPDAHKGRG O28907 72 28 -
LLDLPGIIEGASQGKG O57346 113 8 -
LLDAPGIIVGASSGKG Q58722 135 8 -
MLDLPGIIEGASQGRG GTP1_SCHPO 113 8 -
MLDLPGIIDGAKDGRG YAD6_YEAST 116 8 -
IVDLPGIIYGASQGKG YG3Y_YEAST 114 8 -
LLDVPGLIEGAAGGRG YRB1_HALCU 112 8 -
LLDLPGIIEGAAQGKG DRG2_HUMAN 113 8 -
VADIPGLIEDSHLNKG O45691 240 9 -
VYDIAGLTKGASAGEG YBN5_YEAST 90 26 -
LVEVPGLLEGAALGKG O59329 132 8 -
ILDLPGIIENASYGSA P96085 111 8 -
IADLPGIIEGASMNRG Q18219 221 16 -
IADLPGIIEGASMNRG Q18220 221 16 -
LLDVAGLVPGAHSGRG YG4I_YEAST 81 34 -
VFDIAGLTKGASTGVG O13998 89 25 -
LADVPGILERASQGVG O83724 213 9 -
LIDVAGLVPGAHEGRG O27559 79 32 -
VTDIAGLVKGASEGQG YCHF_CAEEL 89 25 -
VADIPGIIQGASLDKG YHW8_YEAST 392 10 -
IYDIAGLTRGASQGHG YLF2_YEAST 85 25 -
IYDTAGLTRNSSKGEG YEAD_SCHPO 114 25 -

Motif 4 width=19
Element Seqn Id St Int Rpt
GNKFLANIRETDAIGHVVR YCHF_HAEIN 86 1 -
GNQFLSHIREVDAVAMVLR O66865 88 1 -
GNQFLANIREVDLICHVVR Y024_MYCPN 86 1 -
GNQFLANIREVDLICHVVR Y024_MYCGE 86 1 -
GNKFLAHIRECDAICQVVR O53459 87 1 -
GHEFLRHIERTRLLLHVLD P72931 228 1 -
GLDFLRHIERCAVLVHVVD P71909 227 1 -
GNKFLSHIRQVDAICHVVR YYAF_BACSU 87 1 -
GNQFLANIREVDAIVHVVR P73886 87 1 -
GNKFLANIREVSLIVHVVR O51251 87 1 -
GISFLKHIERTKVLAFVLD Y303_HELPY 225 1 -
GNQFLTNIRETEAIGHVVR YCHF_ECOLI 86 1 -
GHEFLRHIERTKFLAHVID O67849 229 1 -
GHQFLRHIERTRVIVHVID OBG_BACSU 227 1 -
GLEFLRHVERCSVLVHVLD P95758 227 1 -
GLEFLRHVERCSVLVHVLD P95722 227 1 -
GTRFLGHVERSATLIHLID O30861 228 1 -
GNRFLAHVREVGVLAHVVR O83161 87 1 -
GHYFLRHIERCEILIHLIS Y384_MYCPN 227 1 -
GHDFLRHIERCEILIHLIS Y384_MYCGE 227 1 -
GIRFLKHLERCRVLIHLVD YHBZ_HAEIN 228 1 -
GNQFLANIKECEVILQVVR O25293 88 1 -
GNRFLSHIRETHAIAHVVR O84094 90 1 -
GNKFLDDLRMASALIHVVD O58261 92 1 -
GIRFLKHLERCRVLLHLID YHBZ_ECOLI 228 1 -
GLDFLRHIERTRLLLFVID O84423 230 1 -
GRQVIAVARTCNLILIVLD DRG_XENLA 132 1 -
GRQVIAVARTCNLILIVLD DRG_MOUSE 132 1 -
GTKFLKHIAKTKILALVID O51722 228 1 -
GREILSVARSADLIVIVLD O27658 145 1 -
GNKFLDDLRQADAFILVVD Q58728 93 1 -
GRQVIAVARTCNLIFMVLD 128U_DROME 132 1 -
GRQVIAVAKSSDLVLMVLD O04174 130 1 -
GKEVISAVRVADLIIIVAD O28136 131 1 -
GRQVISVAKTADLILMMLD YKK3_CAEEL 130 1 -
GKQVITVARTCNLIFIVLD P78786 131 1 -
GNEFLDNLRQSEAVIHVVD O28907 89 1 -
GRQVIAVARTADVVIMMLD O57346 130 1 -
GTEVLSAVRSADLILLTVD Q58722 152 1 -
GRQAVSAARTADLILMVFG GTP1_SCHPO 129 0 -
GKQVIAVARTCNLLFIILD YAD6_YEAST 133 1 -
GRQVVATARTADLVLMVLD YG3Y_YEAST 131 1 -
GKEILSVIRGADLVIFVLS YRB1_HALCU 129 1 -
GRQVIAVARTADVIIMMLD DRG2_HUMAN 130 1 -
GISFLKHIERCESLWYVLD O45691 257 1 -
GNAFLSHIRSVDSIYQVVR YBN5_YEAST 107 1 -
GPQLLAVIRNADAIAIVID O59329 149 1 -
GREILSAVRAADLIVIVTD P96085 128 1 -
GYKFLKHLEYADIVVMVVD Q18219 238 1 -
GYKFLKHLEYADIVVMVVD Q18220 238 1 -
GNKFLDDLRHADALIHVVD YG4I_YEAST 98 1 -
GNAFLSHVRAVDAIYQVVR O13998 106 1 -
GLRFLKHLTRCAGLAFLID O83724 230 1 -
GNKFLDDLRQARAFLHVID O27559 96 1 -
GNAFLSHVSACDALFHLCR YCHF_CAEEL 106 1 -
GLEFLRHIERSNGWVFVLD YHW8_YEAST 409 1 -
GNKFLNDIRHVEGIFQVVR YLF2_YEAST 102 1 -
GNAFLSNIRSVDALFQLVR YEAD_SCHPO 131 1 -