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PR00182

Identifier
ECOLNEIPORIN  [View Relations]  [View Alignment]  
Accession
PR00182
No. of Motifs
5
Creation Date
19-MAR-1993  (UPDATE 07-JUN-1999)
Title
E.coli/Neisseria porin superfamily signature
Database References
PRINTS; PR00183 ECOLIPORIN; PR00184 NEISSPPORIN
PROSITE; PS00576 GRAM_NEG_PORIN; PS00558 EUKARYOTIC_PORIN
PFAM; PF00267 Gram-ve_porins
INTERPRO; IPR001702
PDB; 1OMF
SCOP; 1OMF
CATH; 1OMF
Literature References
1. JAP, B.K. AND WALIAN, P.J.
Biophysics of the structure and function of porins.
Q.REV.BIOPHYS. 23 367-403 (1990).
 
2. NIKAIDO, H.
Porins and specific channels of bacterial outer membranes.
MOL.MICROBIOL. 6 435-442 (1992).
 
3. WEISS, M.S., KREUSCH, A., SCHILTZ, E., NESTEL, U., WELTE, W., 
WECKESSER, J. AND SCHULZ, G.E.
The structure of porin from Rhodobacter casulatus at 1.8A resolution.
FEBS LETT. 280 379-382 (1991).
 
4. PAUPTIT, R.A., SCHIRMER, T., JANSONIUS, J.N., ROSENBUSCH, J.P,
PARKER, M.W., TUCKER, A.D., TSERNOGLOU, D., WIESS, M.S. AND SCHULZ, G.E.
A common channel-forming motif in evolutionarily distant porins
J.STRUCT.BIOL. 107 136-145 (1991).
 
5. KREUSCH, A. AND SCHULZ, G.E. 
Refined structure of the porin from Rhodopseudomonas blastica. 
Comparison with the porin from Rhodobacter capsulatus.
J.MOL.BIOL. 243 891-905 (1994).
 
6. COWAN, S.W.
Bacterial porins: lessons from three high-resolution structures.
CURR.OPIN.STRUCT.BIOL. 3 501-507 (1993).

Documentation
Porins are found in the outer membranes of Gram-negative bacteria,
mitochondria and chloroplasts, where they form ion-selective channels for 
small hydrophilic molecules (up to ~600 Da) [1,2]. X-ray structure analyses
of several bacterial porins [3-5] have revealed a 16-stranded anti-parallel
beta-barrel structure enclosing the transmembrane pore, by contrast with
all other integral membrane proteins described to date, which are alpha-
helical. Three subunits form a trimer; the 3-fold axis is approximately
parallel to the barrel axes and is assumed to be perpendicular to the
membrane plane [6].  
 
From the range of porins now known, similarities have been observed between
porins from different species, and between porins of different specificity
within the same species. But most porins cannot be related to each other on
the basis of sequence alone, and this is reflected in the lengths of the 
known porin sequences, which range from 282-483 residues/monomer.
 
ECOLNEIPORIN is a 5-element fingerprint that provides a signature for both
Neisseria and E.coli/Salmonella-type porins. The fingerprint was derived
from an initial alignment of 8 sequences: the motifs were drawn from
conserved regions spanning virtually the full alignment length. Three
iterations on OWL19.1 were required to reach convergence, at which point
a true set comprising 51 sequences was identified. The fingerprint is
selective for this superfamily, and there is no cross-reaction with
eukaryotic porins.
 
An update on SPTR37_9f identified a true set of 83 sequences, and 1
partial match.
Summary Information
  83 codes involving  5 elements
0 codes involving 4 elements
0 codes involving 3 elements
1 codes involving 2 elements
Composite Feature Index
58383838383
400000
300000
201001
12345
True Positives
NMPC_ECOLI    O08266        O51943        O51944        
O51945 O51946 O51947 O51948
O52693 O52694 O52695 O52696
O52697 O52698 O52699 O52700
O52701 O85030 O87753 O87754
OMA1_NEIGO OMA1_NEIME OMA2_NEIME OMB1_NEIGO
OMB1_NEIME OMB2_NEIGO OMB2_NEIME OMB3_NEIME
OMB4_NEIME OMB_NEILA OMB_NEISI OMPC_ECOLI
OMPC_KLEPN OMPC_SALTI OMPC_SALTY OMPC_SERMA
OMPF_ECOLI OMPF_SALTI OMPF_SALTY OMPF_SERMA
OMPF_XENNE OMPN_ECOLI OMS1_SALTI OMS2_SALTI
P95344 P95345 P95346 P95347
P95348 P95349 P95350 P95351
P95352 PHOE_CITFR PHOE_ECOLI PHOE_ENTCL
PHOE_KLEOX PHOE_KLEPN PHOE_SALTI PHOE_SALTY
PORI_BPPA2 Q05520 Q08249 Q08250
Q08251 Q08252 Q08253 Q08254
Q51056 Q51059 Q51066 Q51067
Q51068 Q51093 Q51094 Q51095
Q51096 Q51100 Q51240 Q51261
Q51271 Q57378 YEDS_ECOLI
True Positive Partials
Codes involving 2 elements
Q45106
Sequence Titles
NMPC_ECOLI  OUTER MEMBRANE PORIN PROTEIN NMPC PRECURSOR - ESCHERICHIA COLI. 
O08266 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
O51943 HYBRID OUTER MEMBRANE PROTEIN IA/IB PRECURSOR - NEISSERIA GONORRHOEAE.
O51944 OUTER MEMBRANE PROTEIN I PRECURSOR - NEISSERIA GONORRHOEAE.
O51945 OUTER MEMBRANE PROTEIN I PRECURSOR - NEISSERIA GONORRHOEAE.
O51946 OUTER MEMBRANE PROTEIN I PRECURSOR - NEISSERIA GONORRHOEAE.
O51947 OUTER MEMBRANE PROTEIN I PRECURSOR - NEISSERIA GONORRHOEAE.
O51948 OUTER MEMBRANE PROTEIN I PRECURSOR - NEISSERIA GONORRHOEAE.
O52693 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52694 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52695 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52696 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52697 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52698 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52699 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52700 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O52701 OUTER MEMBRANE PORIN - NEISSERIA GONORRHOEAE.
O85030 PORIN OMPN - ESCHERICHIA COLI.
O87753 OMPK35 PORIN PRECURSOR - KLEBSIELLA PNEUMONIAE.
O87754 OMPK37 PORIN PRECURSOR - KLEBSIELLA PNEUMONIAE.
OMA1_NEIGO MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
OMA1_NEIME MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA MENINGITIDIS.
OMA2_NEIME MAJOR OUTER MEMBRANE PROTEIN P.IA PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA MENINGITIDIS.
OMB1_NEIGO MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) - NEISSERIA GONORRHOEAE.
OMB1_NEIME MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) (CLASS 3) - NEISSERIA MENINGITIDIS.
OMB2_NEIGO MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) - NEISSERIA GONORRHOEAE.
OMB2_NEIME MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) (CLASS 3) - NEISSERIA MENINGITIDIS.
OMB3_NEIME MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) (CLASS 3) - NEISSERIA MENINGITIDIS.
OMB4_NEIME MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) (CLASS 3) - NEISSERIA MENINGITIDIS.
OMB_NEILA MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) - NEISSERIA LACTAMICA.
OMB_NEISI MAJOR OUTER MEMBRANE PROTEIN P.IB PRECURSOR (PROTEIN IB) (PIB) (PORIN) - NEISSERIA SICCA.
OMPC_ECOLI OUTER MEMBRANE PROTEIN C PRECURSOR (PORIN OMPC) (OUTER MEMBRANE PROTEIN 1B) - ESCHERICHIA COLI.
OMPC_KLEPN OUTER MEMBRANE PROTEIN C PRECURSOR (PORIN OMPC) (PORIN OMPK36) - KLEBSIELLA PNEUMONIAE.
OMPC_SALTI OUTER MEMBRANE PROTEIN C PRECURSOR (PORIN OMPC) - SALMONELLA TYPHI.
OMPC_SALTY OUTER MEMBRANE PROTEIN C PRECURSOR (PORIN OMPC) - SALMONELLA TYPHIMURIUM.
OMPC_SERMA OUTER MEMBRANE PROTEIN C PRECURSOR (PORIN OMPC) - SERRATIA MARCESCENS.
OMPF_ECOLI OUTER MEMBRANE PROTEIN F PRECURSOR (PORIN OMPF) (OUTER MEMBRANE PROTEIN 1A, IA, OR B) - ESCHERICHIA COLI.
OMPF_SALTI OUTER MEMBRANE PROTEIN F PRECURSOR (PORIN OMPF) (OUTER MEMBRANE PROTEIN S3) - SALMONELLA TYPHI.
OMPF_SALTY OUTER MEMBRANE PROTEIN F PRECURSOR (PORIN OMPF) (OUTER MEMBRANE PROTEIN 1A, IA, OR B) - SALMONELLA TYPHIMURIUM.
OMPF_SERMA OUTER MEMBRANE PROTEIN F PRECURSOR (PORIN OMPF) - SERRATIA MARCESCENS.
OMPF_XENNE OUTER MEMBRANE PROTEIN F PRECURSOR (PORIN OMPF) (OUTER MEMBRANE PROTEIN OPNP) - XENORHABDUS NEMATOPHILUS.
OMPN_ECOLI OUTER MEMBRANE PROTEIN N PRECURSOR (PORIN OMPN) - ESCHERICHIA COLI.
OMS1_SALTI OUTER MEMBRANE PROTEIN S1 PRECURSOR - SALMONELLA TYPHI.
OMS2_SALTI OUTER MEMBRANE PROTEIN S2 PRECURSOR - SALMONELLA TYPHI.
P95344 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95345 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95346 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95347 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95348 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95349 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95350 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95351 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
P95352 OUTER MEMBRANE PROTEIN PIB PRECURSOR - NEISSERIA GONORRHOEAE.
PHOE_CITFR OUTER MEMBRANE PORE PROTEIN E PRECURSOR - CITROBACTER FREUNDII.
PHOE_ECOLI OUTER MEMBRANE PORE PROTEIN E PRECURSOR - ESCHERICHIA COLI.
PHOE_ENTCL OUTER MEMBRANE PORE PROTEIN E PRECURSOR - ENTEROBACTER CLOACAE.
PHOE_KLEOX OUTER MEMBRANE PORE PROTEIN E PRECURSOR - KLEBSIELLA OXYTOCA.
PHOE_KLEPN OUTER MEMBRANE PORE PROTEIN E PRECURSOR - KLEBSIELLA PNEUMONIAE.
PHOE_SALTI OUTER MEMBRANE PORE PROTEIN E PRECURSOR - SALMONELLA TYPHI.
PHOE_SALTY OUTER MEMBRANE PORE PROTEIN E PRECURSOR - SALMONELLA TYPHIMURIUM.
PORI_BPPA2 OUTER MEMBRANE PORIN PROTEIN LC PRECURSOR - BACTERIOPHAGE PA-2.
Q05520 MAJOR OUTER MEMBRANE PROTEIN P.IA PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA MENINGITIDIS.
Q08249 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q08250 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q08251 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q08252 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q08253 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q08254 MAJOR OUTER MEMBRANE PROTEIN PI.A PRECURSOR (PROTEIN IA) (PIA) - NEISSERIA GONORRHOEAE.
Q51056 PORIN (PORB) - NEISSERIA GONORRHOEAE.
Q51059 MAJOR OUTER MEMBRANE PROTEIN (PIB) PRECURSOR (PIB) - NEISSERIA GONORRHOEAE.
Q51066 OUTER MEMBRANE PROTEIN IA PRECURSOR - NEISSERIA GONORRHOEAE.
Q51067 OUTER MEMBRANE PROTEIN IA PRECURSOR - NEISSERIA GONORRHOEAE.
Q51068 OUTER MEMBRANE PROTEIN IA PRECURSOR - NEISSERIA GONORRHOEAE.
Q51093 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51094 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51095 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51096 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51100 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51240 PORA A CLASS 1 OUTER MEMBRANE PROTEIN (P1.7,16) PRECURSOR (P1.7,16) - NEISSERIA MENINGITIDIS.
Q51261 PORB PROTEIN PRECURSOR - NEISSERIA MENINGITIDIS.
Q51271 SEROTYPE 15 OUTER MEMBRANE PROTEIN - NEISSERIA MENINGITIDIS.
Q57378 CLASS 3 OUTER MEMBRANE PORIN PRECURSOR - NEISSERIA MENINGITIDIS.
YEDS_ECOLI POTENTIAL OUTER MEMBRANE PROTEIN YEDS PRECURSOR - ESCHERICHIA COLI.

Q45106 OPCP1 - BURKHOLDERIA CEPACIA (PSEUDOMONAS CEPACIA).
Scan History
OWL19_1    3  100  NSINGLE    
OWL25_3 1 250 NSINGLE
SPTR37_9f 2 181 NSINGLE
Initial Motifs
Motif 1  width=12
Element Seqn Id St Int Rpt
GDQTYMRIGFKG OMPC_SALTI 52 52 -
GDQTYMRLGFKG OMPC_ECOLI 52 52 -
IADLGSKIGFKG OMA1_NEIGO 53 53 -
IADFGSKIGFKG S21405 53 53 -
ISDFGSFIGFKG NGOPORA3S 58 58 -
IVDLGSKIGFKG JH0254 34 34 -
GDQSYIRFGFKG PHOE_ECOLI 52 52 -
GDTTYARLGFKG PORI_BPPA2 54 54 -

Motif 2 width=11
Element Seqn Id St Int Rpt
NRESFIGLAGE NGOPORA3S 99 29 -
NRQSFIGLKGG JH0254 74 28 -
NKQSFIGLKGG S21405 93 28 -
NRQSFIGLKGG OMA1_NEIGO 93 28 -
TRVAFAGLKFQ OMPC_ECOLI 94 30 -
TRVAFAGLKFA OMPC_SALTI 94 30 -
THLAFAGLKFG PORI_BPPA2 98 32 -
TRLAFAGLKYK PHOE_ECOLI 95 31 -

Motif 3 width=12
Element Seqn Id St Int Rpt
VRYDSPEFAGLS JH0254 128 43 -
VRYDSPEFAGFR OMA1_NEIGO 147 43 -
ATYRNTDFFGLV OMPC_ECOLI 150 45 -
ATYRNTDFFGLV OMPC_SALTI 150 45 -
ATYRNNDFFGLV PORI_BPPA2 155 46 -
ATYRNTDFFGVI PHOE_ECOLI 152 46 -
VRYDSPEFSGFS NGOPORA3S 155 45 -
VRYDSPEFAGFS S21405 151 47 -

Motif 4 width=13
Element Seqn Id St Int Rpt
SDVYYAGLNYKNG NGOPORA3S 206 39 -
GESYHVGLNYQNS S21405 177 14 -
SESYHAGFNYKNG JH0254 155 15 -
SESYHAGFNYKNS OMA1_NEIGO 173 14 -
AETYTGGLKYDAN OMPC_ECOLI 239 77 -
ATVYTGGLKYDAN OMPC_SALTI 237 75 -
AEVWAAGLKYDAN PORI_BPPA2 238 71 -
AEAWATGLKYDAN PHOE_ECOLI 228 64 -

Motif 5 width=18
Element Seqn Id St Int Rpt
VVVGAEYDFSKRTSALVS OMA1_NEIGO 283 97 -
IDVGATYYFNKNMSAFVD PHOE_ECOLI 306 65 -
VDVGATYYFNKNMSTFVD PORI_BPPA2 317 66 -
IIAGVDYDFSKRTSAIVS Q05520 342 117 -
IIAGVDYDFSKRTSAIVS NGOPORA3S 338 119 -
VVVGAEYDFSKRTSALVS JH0254 269 101 -
VVVGAEYDFSKRTSALVS S21405 294 104 -
VDVGATYYFNKNMSTYVD OMPC_ECOLI 319 67 -
VDVGATYYFNKNMSTYVD OMPC_SALTI 330 80 -
Final Motifs
Motif 1  width=12
Element Seqn Id St Int Rpt
IADLGSKIGFKG O51944 52 52 -
IADLGSKIGFKG O51945 52 52 -
IADLGSKIGFKG O51946 52 52 -
IADLGSKIGFKG O51948 52 52 -
IADLGSKIGFKG Q08249 53 53 -
IADLGSKIGFKG Q08251 53 53 -
IADLGSKIGFKG Q08254 53 53 -
IADLGSKIGFKG Q51056 53 53 -
IADLGSKIGFKG Q51067 53 53 -
IADLGSKIGFKG Q51068 53 53 -
IVDLGSKIGFKG OMB1_NEIME 53 53 -
IVDLGSKIGFKG Q57378 53 53 -
IVDLGSKIGFKG Q51271 53 53 -
IVDLGSKIGFKG Q51261 53 53 -
IVDLGSKIGFKG Q51100 53 53 -
IVDLGSKIGFKG Q51096 53 53 -
IVDLGSKIGFKG Q51094 53 53 -
IVDLGSKIGFKG Q51093 53 53 -
IVDLGSKIGFKG OMB4_NEIME 53 53 -
IVDLGSKIGFKG OMB3_NEIME 53 53 -
IVDLGSKIGFKG OMB2_NEIME 53 53 -
IADLGSKIGFKG O52693 53 53 -
IADLGSKIGFKG Q08253 53 53 -
IADLGSKIGFKG Q08252 53 53 -
IADLGSKIGFKG Q08250 53 53 -
IADLGSKIGFKG OMA1_NEIGO 53 53 -
IANLGSKIGFKG Q51066 53 53 -
IADFGSKIGFKG OMB_NEILA 53 53 -
ISDFGSKIGFKG O52699 53 53 -
ISDFGSKIGFKG O52694 53 53 -
ISDFGSKIGFKG P95347 53 53 -
ISDFGSKIGFKG O52700 53 53 -
ISDFGSKIGFKG O52696 53 53 -
ISDFGSKIGFKG O52695 53 53 -
IADFGSKIGFKG P95351 53 53 -
IADFGSKIGFKG O08266 53 53 -
IADFGSKIGFKG O52697 53 53 -
IADFGSKIGFKG O52698 53 53 -
IADFGSKIGFKG O52701 53 53 -
IADFGSKIGFKG OMB1_NEIGO 53 53 -
IADFGSKIGFKG OMB2_NEIGO 53 53 -
IADFGSKIGFKG Q51059 53 53 -
IADFGSKIGFKG P95344 53 53 -
ISDFGSKIGFKG O51947 53 53 -
ISDFGSKIGFKG O51943 53 53 -
ISDFGSKIGFKG P95345 53 53 -
ISDFGSKIGFKG P95350 53 53 -
ISDFGSKIGFKG P95352 53 53 -
ISDFGSKIGFKG P95348 53 53 -
ISDFGSKIGFKG P95349 53 53 -
ISDFGSKIGFKG P95346 53 53 -
IVGLGSKIGFKG Q51095 53 53 -
IADFGSRIGFKG OMB_NEISI 53 53 -
ISDFGSFIGFKG OMA1_NEIME 68 68 -
ISDFGSFIGFKG Q51240 70 70 -
ISDFGSFIGFKG Q05520 63 63 -
ISDFGSFIGFKG OMA2_NEIME 64 64 -
GDTTYARLGFKG NMPC_ECOLI 54 54 -
GDQTYMRLGFKG OMPC_ECOLI 52 52 -
GDQTYMRIGFKG OMPC_SALTI 52 52 -
GDTTYARLGFKG PORI_BPPA2 54 54 -
GDQTYMRLGVKG OMPC_KLEPN 52 52 -
GDQSYARIGFKG OMS1_SALTI 52 52 -
GDQTYMRVGFKG OMS2_SALTI 52 52 -
GDQTYMRIGFKG OMPC_SALTY 52 52 -
GDQTYVRFGFKG PHOE_ENTCL 52 52 -
GDQSYARLGFKG O85030 52 52 -
GDQSYIRFGFKG PHOE_ECOLI 52 52 -
GDQSYVRFGFKG PHOE_SALTY 51 51 -
GDQTYLRFGFKG O87754 52 52 -
GDMSYARIGFKG YEDS_ECOLI 52 52 -
GDMTYARLGFKG OMPF_ECOLI 58 58 -
GDQSYARLGFKG OMPN_ECOLI 52 52 -
GDQSYVRFGFKG PHOE_SALTI 51 51 -
GDQSYIRLGFKG PHOE_CITFR 52 52 -
GDDSYARIGIKG OMPF_XENNE 53 53 -
ADQTYAQIGFKG OMPF_SALTI 54 54 -
GDQTYVRFGFKG OMPF_SERMA 53 53 -
GDQSYMRFGLRG OMPC_SERMA 52 52 -
ADQTYAQIGFKG OMPF_SALTY 54 54 -
GDQTYVRFGIKG PHOE_KLEPN 52 52 -
GDQTYVRFGIKG PHOE_KLEOX 52 52 -
DDTTYARIGLKG O87753 54 54 -

Motif 2 width=11
Element Seqn Id St Int Rpt
NRQSFIGLKGG O51944 92 28 -
NRQSFIGLKGG O51945 92 28 -
NRQSFIGLKGG O51946 92 28 -
NRQSFIGLKGG O51948 92 28 -
NRQSFIGLKGG Q08249 93 28 -
NRQSFIGLKGG Q08251 93 28 -
NRQSFIGLKGG Q08254 93 28 -
NRQSFIGLKGG Q51056 93 28 -
NRQSFIGLKGG Q51067 93 28 -
NRQSFIGLKGG Q51068 93 28 -
NRQSFIGLKGG OMB1_NEIME 93 28 -
NRQSFIGLKGG Q57378 93 28 -
NRQSFIGLKGG Q51271 93 28 -
NRQSFIGLKGG Q51261 93 28 -
NRQSFIGLKGG Q51100 93 28 -
NRQSFIGLKGG Q51096 93 28 -
NRQSFIGLKGG Q51094 93 28 -
NRQSFIGLKGG Q51093 93 28 -
NRQSFIGLKGG OMB4_NEIME 93 28 -
NRQSFIGLKGG OMB3_NEIME 93 28 -
NRQSFIGLKGG OMB2_NEIME 93 28 -
SRQSFIGLKGG O52693 93 28 -
SRQSFIGLKGG Q08253 93 28 -
SRQSFIGLKGG Q08252 93 28 -
SRQSFIGLKGG Q08250 93 28 -
NRQSFIGLKGG OMA1_NEIGO 93 28 -
NRQSFIGLKGG Q51066 93 28 -
NKQSFIGLKGG OMB_NEILA 93 28 -
NKQSFIGLKGG O52699 93 28 -
NKQSFIGLKGG O52694 93 28 -
NKQSFIGLKGG P95347 93 28 -
NKQSFIGLKGG O52700 93 28 -
NKQSFIGLKGG O52696 93 28 -
NKQSFIGLKGG O52695 93 28 -
NKQSFVGLKGG P95351 93 28 -
NKQSFVGLKGG O08266 93 28 -
NKQSFVGLKGG O52697 93 28 -
NKQSFVGLKGG O52698 93 28 -
NKQSFVGLKGG O52701 93 28 -
NKQSFVGLKGG OMB1_NEIGO 93 28 -
NKQSFVGLKGG OMB2_NEIGO 93 28 -
NKQSFVGLKGG Q51059 93 28 -
NKQSFVGLKGG P95344 93 28 -
NKQSFVGLKGG O51947 93 28 -
NKQSFVGLKGG O51943 93 28 -
NKQSFVGLKGG P95345 93 28 -
NKQSFVGLKGG P95350 93 28 -
NKQSFVGLKGG P95352 93 28 -
NKQSFVGLKGG P95348 93 28 -
NKQSFVGLKGG P95349 93 28 -
NKQSFIGLKGG P95346 93 28 -
NRQSFIGLKGG Q51095 93 28 -
TRESFIGLEGG OMB_NEISI 93 28 -
NRESFIGLAGE OMA1_NEIME 109 29 -
NRESFIGLAGE Q51240 111 29 -
NRESFVGLAGE Q05520 104 29 -
NRESFVGLAGE OMA2_NEIME 105 29 -
TRLAFAGLKFG NMPC_ECOLI 98 32 -
TRVAFAGLKFQ OMPC_ECOLI 94 30 -
TRVAFAGLKFA OMPC_SALTI 94 30 -
THLAFAGLKFG PORI_BPPA2 98 32 -
TRLAFAGLKFG OMPC_KLEPN 95 31 -
TRLGFAGLKFG OMS1_SALTI 95 31 -
TRLAFAGLKFG OMS2_SALTI 95 31 -
TRVAFAGLKFA OMPC_SALTY 94 30 -
TRLAFAGLKLK PHOE_ENTCL 94 30 -
TRLAFAGLKFA O85030 95 31 -
TRLAFAGLKYK PHOE_ECOLI 95 31 -
TRLAFAGLKLK PHOE_SALTY 94 31 -
TRLAFAGIKVG O87754 95 31 -
TRLAFAGLGFG YEDS_ECOLI 95 31 -
TRLAFAGLKYA OMPF_ECOLI 103 33 -
TRLAFAGLKFA OMPN_ECOLI 95 31 -
TRLAFAGLKLK PHOE_SALTI 94 31 -
TRLAFAGSKLK PHOE_CITFR 95 31 -
TRLAFAGLKFA OMPF_XENNE 96 31 -
VRLAFAGLKYA OMPF_SALTI 98 32 -
TRLGFAGLKFA OMPF_SERMA 97 32 -
TRYGFAGLKFG OMPC_SERMA 95 31 -
VRLAFAGLKYA OMPF_SALTY 98 32 -
TRLAFAGVKLK PHOE_KLEPN 95 31 -
TRLAFAGVKVK PHOE_KLEOX 94 30 -
TRLAFAGLKAG O87753 96 30 -

Motif 3 width=12
Element Seqn Id St Int Rpt
VRYDSPEFAGFS O51944 146 43 -
VRYDSPEFAGFS O51945 146 43 -
VRYDSPEFAGFS O51946 146 43 -
VRYDSPEFAGFS O51948 146 43 -
VRYDSPEFAGFS Q08249 147 43 -
VRYDSPEFAGFS Q08251 147 43 -
VRYDSPEFAGFS Q08254 147 43 -
VRYDSPEFAGFS Q51056 147 43 -
VRYDSPEFAGFS Q51067 147 43 -
VRYDSPEFAGFS Q51068 147 43 -
VRYDSPEFAGLS OMB1_NEIME 147 43 -
VRYDSPEFAGLS Q57378 147 43 -
VRYDSPEFAGLS Q51271 147 43 -
VRYDSPEFAGLS Q51261 147 43 -
VRYDSPEFAGLS Q51100 147 43 -
VRYDSPEFAGLS Q51096 147 43 -
VRYDSPEFAGLS Q51094 147 43 -
VRYDSPEFAGLS Q51093 147 43 -
VRYDSPEFAGLS OMB4_NEIME 147 43 -
VRYDSPEFAGLS OMB3_NEIME 147 43 -
VRYDSPEFAGLS OMB2_NEIME 147 43 -
VRYDSPEFAGFS O52693 147 43 -
VRYDSPEFAGFS Q08253 147 43 -
VRYDSPEFAGFS Q08252 147 43 -
VRYDSPEFAGFS Q08250 147 43 -
VRYDSPEFAGFR OMA1_NEIGO 147 43 -
VRYDSPEFAGFS Q51066 147 43 -
VRYDSPEFAGFS OMB_NEILA 151 47 -
ARYDSPEFAGFS O52699 151 47 -
ARYDSPEFAGFS O52694 151 47 -
ARYDSPEFAGFS P95347 151 47 -
ARYDSPEFAGFS O52700 151 47 -
ARYDSPEFAGFS O52696 151 47 -
ARYDSPEFAGFS O52695 151 47 -
VRYDSPEFAGFS P95351 151 47 -
VRYDSPEFAGFS O08266 151 47 -
VRYDSPEFAGFS O52697 151 47 -
VRYDSPEFAGFS O52698 151 47 -
VRYDSPEFAGFS O52701 151 47 -
VRYDSPEFAGFS OMB1_NEIGO 151 47 -
VRYDSPEFAGFS OMB2_NEIGO 151 47 -
VRYDSPEFAGFS Q51059 151 47 -
ARYDSPEFAGFS P95344 151 47 -
VRYDSPEFAGFS O51947 151 47 -
ARYDSPEFAGFS O51943 151 47 -
ARYDSPEFAGFS P95345 151 47 -
ARYDSPEFAGFS P95350 151 47 -
ARYDSPEFAGFS P95352 151 47 -
ARYDSPEFAGFS P95348 151 47 -
ARYDSPEFAGFS P95349 151 47 -
ARYDSPEFGGFS P95346 151 47 -
VRYDSPEFAGLS Q51095 147 43 -
VRYDSPVFAGFS OMB_NEISI 151 47 -
VRYDSPEFSGFS OMA1_NEIME 165 45 -
VRYDSPEFSGFS Q51240 167 45 -
VRYDSPEFSGFS Q05520 160 45 -
VRYDSPDFSGFS OMA2_NEIME 161 45 -
ATYRNNDFFGLV NMPC_ECOLI 155 46 -
ATYRNTDFFGLV OMPC_ECOLI 150 45 -
ATYRNTDFFGLV OMPC_SALTI 150 45 -
ATYRNNDFFGLV PORI_BPPA2 155 46 -
ATYRNSDFFGLV OMPC_KLEPN 151 45 -
ATYRNTDFFGLV OMS1_SALTI 152 46 -
ATYRNTDFFGLV OMS2_SALTI 152 46 -
ATYRNTDFFGLV OMPC_SALTY 150 45 -
ATYRNTDFFGAI PHOE_ENTCL 151 46 -
ATYRNTDFFGLV O85030 152 46 -
ATYRNTDFFGVI PHOE_ECOLI 152 46 -
ATYRNTDFFGIV PHOE_SALTY 151 46 -
ATYRNSDFFGLV O87754 152 46 -
ATYRNNGFFGXV YEDS_ECOLI 152 46 -
ATYRNSNFFGLV OMPF_ECOLI 159 45 -
ATYRNTDFFGLV OMPN_ECOLI 152 46 -
ATYRNTDFFGIV PHOE_SALTI 151 46 -
ATYRNTDFFGVV PHOE_CITFR 152 46 -
LTYRNTDFFGLV OMPF_XENNE 153 46 -
LTYRNSDFFGLV OMPF_SALTI 157 48 -
ATYRNNNFFGLV OMPF_SERMA 154 46 -
ATYRNNDFFGLV OMPC_SERMA 151 45 -
LTYRNSDFFGLV OMPF_SALTY 157 48 -
ATYRNTDFFGLV PHOE_KLEPN 152 46 -
ATYRNTDFFGVV PHOE_KLEOX 151 46 -
ATYRNSDFFGLV O87753 153 46 -

Motif 4 width=13
Element Seqn Id St Int Rpt
SESYHAGFNYKNS O51944 173 15 -
SESYHAGFNYKNS O51945 173 15 -
SESYHAGFNYKNS O51946 173 15 -
SESYHAGFNYKNS O51948 173 15 -
SESYHAGFNYKNS Q08249 174 15 -
SESYHAGFNYKNS Q08251 174 15 -
SESYHAGFNYKNS Q08254 174 15 -
SESYHAGFNYKNS Q51056 174 15 -
SESYHAGFNYKNS Q51067 174 15 -
SESYHAGFNYKNS Q51068 174 15 -
SESYHAGFNYKNG OMB1_NEIME 174 15 -
SESYHAGFNYKNG Q57378 174 15 -
SESYHAGFNYKNG Q51271 174 15 -
SESYHAGFNYKNG Q51261 174 15 -
SESYHAGFNYKNG Q51100 174 15 -
SESYHAGFNYKNG Q51096 174 15 -
SESYHAGFNYKNG Q51094 174 15 -
SESYHAGFNYKNG Q51093 174 15 -
SESYHAGFNYKNG OMB4_NEIME 174 15 -
SESYHAGFNYKNG OMB3_NEIME 174 15 -
SESYHAGFNYKNG OMB2_NEIME 174 15 -
SESYHAGFNYKNS O52693 174 15 -
SESYHAGFNYKNS Q08253 174 15 -
SESYHAGFNYKNS Q08252 174 15 -
SESYHAGFNYKNS Q08250 174 15 -
SESYHAGFNYKNS OMA1_NEIGO 173 14 -
SESYHAGFNYKNS Q51066 174 15 -
GESYHVGLNYQNS OMB_NEILA 177 14 -
GESYHVGLNYRNN O52699 177 14 -
GESYHVGLNYRNG O52694 177 14 -
GESYHVGLNYRNG P95347 177 14 -
GESYHVGLNYRNG O52700 177 14 -
GESYHVGLNYRNG O52696 177 14 -
GESYHVGLNYRNG O52695 177 14 -
GESYHVGLNYRNN P95351 177 14 -
GESYHVGLNYQNS O08266 177 14 -
GESYHVGLNYQNS O52697 177 14 -
GESYHVGLNYQNS O52698 177 14 -
GESYHVGLNYQNS O52701 177 14 -
GESYHVGLNYQNS OMB1_NEIGO 177 14 -
GESYHVGLNYQNS OMB2_NEIGO 177 14 -
GESYHVGLNYQNS Q51059 177 14 -
GESYHVGLNYRNG P95344 177 14 -
GESYHVGLNYRNN O51947 177 14 -
GESYHVGLNYRNG O51943 177 14 -
GESYHVGLNYRNG P95345 177 14 -
GESYHVGLNYRNG P95350 177 14 -
GESYHVGLNYRNG P95352 177 14 -
GESYHVGLNYQNS P95348 177 14 -
GESYHVGLNYQNS P95349 177 14 -
GESYHVGLNYRNG P95346 177 14 -
SESYHAGFNYKNG Q51095 174 15 -
RHSFDLGLNYENS OMB_NEISI 186 23 -
SDVYYAGLNYKNG OMA1_NEIME 216 39 -
SDVYYAGLNYKNG Q51240 218 39 -
SDVYYAGLNYKNG Q05520 212 40 -
SDVYYAGLNYKNG OMA2_NEIME 211 38 -
AEVWAAGLKYDAN NMPC_ECOLI 238 71 -
AETYTGGLKYDAN OMPC_ECOLI 239 77 -
ATVYTGGLKYDAN OMPC_SALTI 237 75 -
AEVWAAGLKYDAN PORI_BPPA2 238 71 -
AETYTGGLKYDAN OMPC_KLEPN 236 73 -
AEAWTIGAKYDAY OMS1_SALTI 251 87 -
ADAWTAGLKYDAN OMS2_SALTI 245 81 -
ATVYTGGLKYDAN OMPC_SALTY 237 75 -
AEAWATGLKYDAN PHOE_ENTCL 227 64 -
ADAWTAGLKYDAN O85030 238 74 -
AEAWATGLKYDAN PHOE_ECOLI 228 64 -
AEAWATGVKYDAN PHOE_SALTY 227 64 -
AEAWTAGLKYDAN O87754 243 79 -
AEAWTVGAKYDAN YEDS_ECOLI 250 86 -
AEQWATGLKYDAN OMPF_ECOLI 233 62 -
ADAWTAGLKYDAN OMPN_ECOLI 238 74 -
AEGWATGVKYDAN PHOE_SALTI 227 64 -
AEAWATGLKYDAN PHOE_CITFR 228 64 -
AEAWNIGAKYDAN OMPF_XENNE 235 70 -
AESWAVGAKYDAN OMPF_SALTI 231 62 -
ADAWTVGAKYDAN OMPF_SERMA 231 65 -
AEGYSGGLKYDAN OMPC_SERMA 238 75 -
AASWAVGAKYDAN OMPF_SALTY 231 62 -
AEAWATGLKYDAN PHOE_KLEPN 228 64 -
AEAWATGLKYDAN PHOE_KLEOX 226 63 -
AEAWATSAKYDAN O87753 227 62 -

Motif 5 width=18
Element Seqn Id St Int Rpt
VVVGAEYDFSKRTSALVS O51944 283 97 -
VVVGAEYDFSKRTSALVS O51945 283 97 -
VVVGAEYDFSKRTSALVS O51946 283 97 -
VVVGAEYDFSKRTSALVS O51948 283 97 -
VVVGAEYDFSKRTSALVS Q08249 284 97 -
VVVGAEYDFSKRTSALVS Q08251 284 97 -
VVVGAEYDFSKRTSALVS Q08254 284 97 -
VVVGAEYDFSKRTSALVS Q51056 284 97 -
VVVGAEYDFSKRTSALVS Q51067 284 97 -
VVVGAEYDFSKRTSALVS Q51068 284 97 -
VVVGAEYDFSKRTSALVS OMB1_NEIME 288 101 -
VVVGAEYDFSKRTSALVS Q57378 289 102 -
VVVGAEYDFSKRTSALVS Q51271 288 101 -
VVVGAEYDFSKRTSALVS Q51261 286 99 -
VVVGAEYDFSKRTSALVS Q51100 289 102 -
VVVGAEYDFSKRTSALVS Q51096 287 100 -
VVVGAEYDFSKRTSALVS Q51094 287 100 -
VVVGAEYDFSKRTSALVS Q51093 286 99 -
VVVGAEYDFSKRTSALVS OMB4_NEIME 288 101 -
VVVGAEYDFSKRTSALVS OMB3_NEIME 288 101 -
VVVGAEYDFSKRTSALVS OMB2_NEIME 288 101 -
VVVGAEYDFSKRTSALVS O52693 284 97 -
VVVGAEYDFSKRTSALVS Q08253 284 97 -
VVVGAEYDFSKRTSALVS Q08252 284 97 -
VVVGAEYDFSKRTSALVS Q08250 284 97 -
VVVGAEYDFSKRTSALVS Q51066 284 97 -
VVVGAEYDFSKRTSALVS OMB_NEILA 294 104 -
VVVGAEYDFSKRTSALVS O52699 303 113 -
VVVGAEYDFSKRTSALVS O52694 305 115 -
VVVGAEYDFSKRTSALVS P95347 305 115 -
VVVGAEYDFSKRTSALVS O52700 305 115 -
VVVGAEYDFSKRTSALVS O52696 305 115 -
VVVGAEYDFSKRTSALVS O52695 305 115 -
VVVGAEYDFSKRTSALVS P95351 305 115 -
VVVGAEYDFSKRTSALVS O08266 305 115 -
VVVGAEYDFSKRTSALVS O52697 305 115 -
VVVGAEYDFSKRTSALVS O52698 305 115 -
VVVGAEYDFSKRTSALVS O52701 305 115 -
VVVGAEYDFSKRTSALVS OMB1_NEIGO 305 115 -
VVVGAEYDFSKRTSALVS OMB2_NEIGO 305 115 -
VVVGAEYDFSKRTSALVS Q51059 307 117 -
VVVGAEYDFSKRTSALVS P95344 305 115 -
VVVGAEYDFSKRTSALVS O51947 296 106 -
VVVGAEYDFSKRTSALVS O51943 304 114 -
VVVGAEYDFSKRTSALVS P95345 305 115 -
VVVGAEYDFSKRTSALVS P95350 305 115 -
VVVGAEYDFSKRTSALVS P95352 305 115 -
VVVGAEYDFSKRTSALVS P95348 305 115 -
VVVGAEYDFSKRTSALVS P95349 305 115 -
VVVGAEYDFSKRTSALVS P95346 305 115 -
VVVGAEYDFSKRTSVLVS Q51095 289 102 -
VIVGADYDFSKRTSALVS OMB_NEISI 314 115 -
IIAGVDYDFSKRTSAIVS OMA1_NEIME 349 120 -
IIAGVDYDFSKRTSAIVS Q51240 348 117 -
IIAGVDYDFSKRTSAIVS OMA2_NEIME 343 119 -
VDVGATYYFKKNMSTFVD NMPC_ECOLI 317 66 -
VDVGATYYFNKNMSTYVD OMPC_KLEPN 315 66 -
VDVGMTYYFNKNMSTYVD OMS1_SALTI 345 81 -
ADVGATYYFNKNFSTYVD OMS2_SALTI 334 76 -
VDVGATYYFNTNMSTYVD OMPC_SALTY 330 80 -
IDVGATYYFNKNMSAFVD PHOE_ENTCL 305 65 -
ADVGATYYFNKNMSTYVD O85030 328 77 -
IDVGATYYFNKNMSAFVD PHOE_SALTY 305 65 -
MDVGATYYFNRNMSTYVD O87754 325 69 -
VDIGATYYFNKNMSTYVD YEDS_ECOLI 348 85 -
FEVGATYYFNKNMSTYVD OMPF_ECOLI 317 71 -
ADIGATYYFNKNMSTYVD OMPN_ECOLI 328 77 -
IDVGAIYYFNKNMSAFVD PHOE_SALTI 305 65 -
IDVGATYYFNKNMSAFVD PHOE_CITFR 306 65 -
VSVGTYYYFNKNLSTYVD OMPF_XENNE 324 76 -
IQAGATYYFNKNMNVWVD OMPF_SALTI 316 72 -
VSVGTTYYFNKNMSTYVD OMPF_SERMA 326 82 -
VDLGATYFFNKNMSTYVD OMPC_SERMA 328 77 -
IQAGATYYFNKNMNVWVD OMPF_SALTY 316 72 -
IDVGLTYYFNKNMNAFVD PHOE_KLEPN 306 65 -
IDVGVTYYFNKNMNAFVD PHOE_KLEOX 304 65 -
IEVGTWYYFNKNMNVYAA O87753 311 71 -
VVVGAEYDFSKRTSALVS OMA1_NEIGO 283 97 -
IDVGATYYFNKNMSAFVD PHOE_ECOLI 306 65 -
VDVGATYYFNKNMSTYVD OMPC_ECOLI 319 67 -
VDVGATYYFNKNMSTYVD OMPC_SALTI 330 80 -
VDVGATYYFNKNMSTFVD PORI_BPPA2 317 66 -
IIAGVDYDFSKRTSAIVS Q05520 342 117 -