WORKLIST ENTRIES (1):

OESTROGENR View alignment       Oestrogen receptor signature
 Type of fingerprint: COMPOUND with 8  elements
Links:
   PRINTS; PR00047 STROIDFINGER; PR00398 STRDHORMONER
   PRINTS; PR00521 ANDROGENR; PR01282 COUPTNFACTOR; PR01283 ECDYSTEROIDR
   PRINTS; PR00528 GLCORTICOIDR; PR01284 NUCLEARECPTR; PR00350 VITAMINDR
   PRINTS; PR00544 PROGESTRONER; PR01288 PROXISOMEPAR; PR00545 RETINOIDXR
   PRINTS; PR01293 RORNUCRECPTR; PR00546 THYROIDHORMR; PR02034 LIVERXRECPTR
   INTERPRO; IPR001292
   PFAM; PF02159 Oest_recep
   MIM; 133430; 601663

 Creation date 08-JUN-1996; UPDATE 08-JUL-2010

   1. NUCLEAR RECEPTORS NOMENCLATURE COMMITTEE
   A unified nomenclature system for the nuclear receptor superfamily.
   CELL 97 161-163 (1999).
  
   2. NISHIKAWA, J-I., KITAURA, M., IMAGAWA, M. AND NISHIHARA, T.
   Vitamin D receptor contains multiple dimerisation interfaces that
   are functionally different.
   NUCLEIC ACIDS RES. 23(4) 606-611 (1995).
  
   3. DE VOS, P., SCHMITT, J., VERHOEVEN, G. AND STUNNENBERG, G.
   Human androgen receptor expressed in HeLa cells activates transcription
   in vitro.
   NUCLEIC ACIDS RES. 22(7) 1161-1166 (1994).
  
   4. DANIELIAN, P.S., WHITE, R., LEES, J.A. AND PARKER, M.G.
   Identification of a conserved region required for hormone dependent
   transcriptional activation by steroid hormone receptors.
   EMBO J. 11 1025-1033 (1992).

   Steroid or nuclear hormone receptors (NRs) constitute an important super-
   family of transcription regulators that are involved in widely diverse 
   physiological functions, including control of embryonic development, cell
   differentiation and homeostasis [1]. Members of the superfamily include the
   steroid hormone receptors and receptors for thyroid hormone, retinoids, 
   1,25-dihydroxy-vitamin D3 and a variety of other ligands. The proteins 
   function as dimeric molecules in nuclei to regulate the transcription of 
   target genes in a ligand-responsive manner [2,3]. In addition to C-terminal
   ligand-binding domains, these nuclear receptors contain a highly-conserved,
   N-terminal zinc-finger that mediates specific binding to target DNA 
   sequences, termed ligand-responsive elements. In the absence of ligand,
   steroid hormone receptors are thought to be weakly associated with nuclear
   components; hormone binding greatly increases receptor affinity.
  
   NRs are extremely important in medical research, a large number of them
   being implicated in diseases such as cancer, diabetes, hormone resistance
   syndromes, etc. [1]. While several NRs act as ligand-inducible transcription
   factors, many do not yet have a defined ligand and are accordingly termed 
   "orphan" receptors. During the last decade, more than 300 NRs have been
   described, many of which are orphans, which cannot easily be named due to 
   current nomenclature confusions in the literature. However, a new system 
   has recently been introduced in an attempt to rationalise the increasingly 
   complex set of names used to describe superfamily members [1].
  
   The oestrogen receptor consists of 3 functional and structural domains:
   an N-terminal (modulatory) domain; a DNA binding domain that mediates
   specific binding to target DNA sequences, termed ligand-responsive
   elements; and a hormone binding domain. The N-terminal domain is unique to
   the oestrogen receptors and spans approximately the first 180 residues; the
   highly-conserved DNA-binding domain is smaller (around 65 residues) and
   occupies the central portion of the protein; and the hormone binding
   domain lies at the receptor C-terminus. 
  
   The oestrogen receptor [4] stimulates transcription via 2 distinct
   transcriptional activation domains: TAF-1 in the N-terminal domain, and
   TAF-2 in the hormone-binding domain. TAF-2 activity requires a region in
   the C-terminus of the hormone-binding domain (between residues 538-552 in
   the mouse oestrogen receptor) that is conserved in many nuclear hormone
   receptors. It is therefore suggested that this region may be essential
   for ligand-dependent transcriptional activation by other members of the
   nuclear receptor family [3].
  
   OESTROGENR is an 8-element fingerprint that provides a signature for the
   oestrogen receptors. The fingerprint was derived from an initial alignment
   of 4 sequences: the motifs span the N-terminal modulatory domain preceding
   the highly-conserved zinc-binding region shared by the steroid hormone
   receptor family. Two iterations on OWL28.0 were required to reach
   convergence, at which point a true set comprising 8 sequences was
   identified. A single partial match was also found (ORZMER), an oestrogen
   receptor from the killifish that matches motifs 5 and 6.
  
   An update on SPTR57.15_40.15f identified a true set of 46 sequences,
   together with numerous partial matches, all of which are family members
   that fail to match one or more motifs.

  SUMMARY INFORMATION
     46 codes involving  8 elements
      3 codes involving  7 elements
      3 codes involving  6 elements
      2 codes involving  5 elements
      2 codes involving  4 elements
      0 codes involving  3 elements
      1 codes involving  2 elements

   COMPOSITE FINGERPRINT INDEX
  
    8|  46   46   46   46   46   46   46   46  
    7|   3    3    3    3    3    3    3    0  
    6|   2    1    3    1    2    3    3    3  
    5|   1    0    0    1    2    2    2    2  
    4|   1    1    0    0    2    2    1    1  
    3|   0    0    0    0    0    0    0    0  
    2|   0    0    0    0    0    1    1    0  
   --+-----------------------------------------
     |   1    2    3    4    5    6    7    8  

True positives..
 A8KAF4_HUMAN   Q5T5H7_HUMAN   Q14268_HUMAN   Q14267_HUMAN   
 ESR1_HUMAN     B6ZGU3_HUMAN   B6CK22_TRAOB   B6CK20_CERAE   
 B6CK18_HYLLA   B6CK17_PONPY   B6CK16_9PRIM   B6CK15_PANPA   
 B6CK21_COLGU   B6CK19_PAPAN   A2TEV4_PIG     ESR1_PIG       
 B6CK23_ATEPA   B6CK24_CEBAP   ESR1_FELCA     ESR1_BOVIN     
 B3VQI7_MOUSE   Q3UT58_MOUSE   ESR1_MOUSE     ESR1_MESAU     
 D0FYH4_RAT     ESR1_RAT       ESR1_HORSE     A8QZK3_9SAUR   
 B6E1V9_9SAUR   ESR1_CHICK     B6ZK18_9FALC   B6ZK19_TORTR   
 Q1EDB6_MICOH   Q8AYH0_COTJA   B6CZ21_9SAUR   Q3LGB2_CRONI   
 ESR1_TAEGU     Q765N7_ALLMI   B2NIY0_XENLA   B2NIY1_XENLA   
 Q8UWB0_CAICR   Q25C14_XENTR   ESR1_XENLA     Q6W5G7_XENLA   
 Q0KKA1_9AMPH   A8VFJ8_PLEWA   
Subfamily:  Codes involving 7 elements
 Subfamily True positives..
 Q9H2M1_HUMAN   Q9H2M2_HUMAN   Q8UWA9_CNEUN   
Subfamily:  Codes involving 6 elements
 Subfamily True positives..
 Q2HWK5_EUBMA   B6F0Z4_PRODO   B6F101_PROAN   
Subfamily:  Codes involving 5 elements
 Subfamily True positives..
 B4E3R5_HUMAN   Q6W5G9_XENTR   
Subfamily:  Codes involving 4 elements
 Subfamily True positives..
 B6F0Z7_ACISC   B6F0Z9_9ACTI   
Subfamily:  Codes involving 2 elements
 Subfamily True positives..
 B6F0Z6_ACISC   


  PROTEIN TITLES
   A8KAF4_HUMAN     cDNA FLJ77952, highly similar to Homo sapiens oestrogen rece
   Q5T5H7_HUMAN     Estrogen receptor 1 - Homo sapiens 
   Q14268_HUMAN     Estrogen receptor-related protein protein - Homo sapiens 
   Q14267_HUMAN     Estrogen receptor-related protein - Homo sapiens 
   ESR1_HUMAN       Estrogen receptor - Homo sapiens 
   B6ZGU3_HUMAN     Estrogen receptor 1 - Homo sapiens 
   B6CK22_TRAOB     Estrogen receptor alpha - Trachypithecus obscurus 
   B6CK20_CERAE     Estrogen receptor alpha - Cercopithecus aethiops 
   B6CK18_HYLLA     Estrogen receptor alpha - Hylobates lar 
   B6CK17_PONPY     Estrogen receptor alpha - Pongo pygmaeus 
   B6CK16_9PRIM     Estrogen receptor alpha - Gorilla gorilla 
   B6CK15_PANPA     Estrogen receptor alpha - Pan paniscus 
   B6CK21_COLGU     Estrogen receptor alpha - Colobus guereza 
   B6CK19_PAPAN     Estrogen receptor alpha - Papio anubis 
   A2TEV4_PIG       Estrogen receptor alpha - Sus scrofa 
   ESR1_PIG         Estrogen receptor - Sus scrofa 
   B6CK23_ATEPA     Estrogen receptor alpha - Ateles paniscus 
   B6CK24_CEBAP     Estrogen receptor alpha - Cebus apella 
   ESR1_FELCA       Estrogen receptor - Felis catus 
   ESR1_BOVIN       Estrogen receptor - Bos taurus 
   B3VQI7_MOUSE     Estrogen receptor alpha variant U1 - Mus musculus 
   Q3UT58_MOUSE     Putative uncharacterized protein - Mus musculus 
   ESR1_MOUSE       Estrogen receptor - Mus musculus 
   ESR1_MESAU       Estrogen receptor - Mesocricetus auratus 
   D0FYH4_RAT       Estrogen receptor alpha - Rattus norvegicus 
   ESR1_RAT         Estrogen receptor - Rattus norvegicus 
   ESR1_HORSE       Estrogen receptor - Equus caballus 
   A8QZK3_9SAUR     Estrogen receptor alpha - Pseudemys nelsoni 
   B6E1V9_9SAUR     Estrogen receptor - Chrysemys picta 
   ESR1_CHICK       Estrogen receptor - Gallus gallus 
   B6ZK18_9FALC     Estrogen receptor alpha - Gyps africanus 
   B6ZK19_TORTR     Estrogen receptor alpha - Torgos tracheliotus 
   Q1EDB6_MICOH     Estrogen receptor alpha - Microtus ochrogaster 
   Q8AYH0_COTJA     Estrogen receptor alpha - Coturnix coturnix japonica 
   B6CZ21_9SAUR     Estrogen receptor alpha - Lepidochelys olivacea 
   Q3LGB2_CRONI     Estrogen receptor alpha - Crocodylus niloticus 
   ESR1_TAEGU       Estrogen receptor - Taeniopygia guttata 
   Q765N7_ALLMI     Estrogen receptor a - Alligator mississippiensis 
   B2NIY0_XENLA     Brain estrogen receptor alpha1 - Xenopus laevis 
   B2NIY1_XENLA     Brain estrogen receptor alpha2 - Xenopus laevis 
   Q8UWB0_CAICR     Estrogen receptor - Caiman crocodilus 
   Q25C14_XENTR     Estrogen receptor alpha - Xenopus tropicalis 
   ESR1_XENLA       Estrogen receptor - Xenopus laevis 
   Q6W5G7_XENLA     Estrogen receptor alpha 1 - Xenopus laevis 
   Q0KKA1_9AMPH     Estrogen receptor alpha - Andrias japonicus 
   A8VFJ8_PLEWA     Estrogen receptor alpha - Pleurodeles waltlii 
 
   Q9H2M1_HUMAN     Estrogen receptor 1 - Homo sapiens 
   Q9H2M2_HUMAN     Estrogen receptor alpha - Homo sapiens 
   Q8UWA9_CNEUN     Estrogen receptor - Cnemidophorus uniparens 
 
   Q2HWK5_EUBMA     Estrogen receptor alpha - Eublepharis macularius 
   B6F0Z4_PRODO     Estrogen receptor alpha - Protopterus dolloi 
   B6F101_PROAN     Estrogen receptor alpha - Protopterus annectens 
 
   B4E3R5_HUMAN     cDNA FLJ51616, highly similar to Estrogen receptor - Homo sa
   Q6W5G9_XENTR     Estrogen receptor alpha - Xenopus tropicalis 
 
   B6F0Z7_ACISC     Estrogen receptor alpha2 - Acipenser schrenckii 
   B6F0Z9_9ACTI     Estrogen receptor alpha - Atractosteus tropicus 
 
   B6F0Z6_ACISC     Estrogen receptor alpha1 - Acipenser schrenckii 

SCAN HISTORY OWL28_0 2 100 NSINGLE SPTR37_9f 2 11 NSINGLE SPTR57.15_40.15f 3 300 NSINGLE INITIAL MOTIF SETS OESTROGENR1 Length of motif = 19 Motif number = 1 Oestrogen receptor motif I - 1 PCODE ST INT HTKASGMALLHQIQGNELE ESTR_HUMAN 6 6 HTKASGMALLHQIQGNELE ESTR_MOUSE 6 6 HTKASGMALLHQIQGNELE ESTR_RAT 6 6 HTKASGVTLLHQIQGTELE ESTR_CHICK 6 6 OESTROGENR2 Length of motif = 18 Motif number = 2 Oestrogen receptor motif II - 1 PCODE ST INT LNRPQLKIPLERPLGEVY ESTR_HUMAN 26 1 LNRPQLKMPMERALGEVY ESTR_MOUSE 26 1 LNRPQLKMPMERALGEVY ESTR_RAT 26 1 LSRPQLKIPLERSLSDMY ESTR_CHICK 26 1 OESTROGENR3 Length of motif = 18 Motif number = 3 Oestrogen receptor motif III - 1 PCODE ST INT DSSKPAVYNYPEGAAYEF ESTR_HUMAN 45 1 DNSKPTVFNYPEGAAYEF ESTR_MOUSE 45 1 DNSKPAVFNYPEGAAYEF ESTR_RAT 45 1 ESNKTGVFNYPEGATYDF ESTR_CHICK 45 1 OESTROGENR4 Length of motif = 16 Motif number = 4 Oestrogen receptor motif IV - 1 PCODE ST INT AQVYGQTGLPYGPGSE ESTR_HUMAN 70 7 APVYGQSGIAYGPGSE ESTR_MOUSE 74 11 APVYGQSSITYGPGSE ESTR_RAT 75 12 APVYGSTTLSYAPTSE ESTR_CHICK 66 3 OESTROGENR5 Length of motif = 15 Motif number = 5 Oestrogen receptor motif V - 1 PCODE ST INT FPPLNSVSPSPLMLL ESTR_HUMAN 97 11 FPQLNSVSPSPLMLL ESTR_MOUSE 101 11 FPQLNSVSPSPLMLL ESTR_RAT 102 11 FHSLNNVPPSPVVFL ESTR_CHICK 91 9 OESTROGENR6 Length of motif = 17 Motif number = 6 Oestrogen receptor motif VI - 1 PCODE ST INT PQLSPFLQPHGQQVPYY ESTR_HUMAN 115 3 PQLSPFLHPHGQQVPYY ESTR_MOUSE 119 3 PHVSPFLHPHGHQVPYY ESTR_RAT 120 3 PQLSPFIHHHSQQVPYY ESTR_CHICK 109 3 OESTROGENR7 Length of motif = 20 Motif number = 7 Oestrogen receptor motif VII - 1 PCODE ST INT LENEPSGYTVREAGPPAFYR ESTR_HUMAN 132 0 LENEPSAYAVRDTGPPAFYR ESTR_MOUSE 136 0 LENEPSAYAVRDTGPPAFYR ESTR_RAT 137 0 LENEQGSFGMREAAPPAFYR ESTR_CHICK 126 0 OESTROGENR8 Length of motif = 20 Motif number = 8 Oestrogen receptor motif VIII - 1 PCODE ST INT NSDNRRQGGRERLASTNDKG ESTR_HUMAN 153 1 NSDNRRQNGRERLSSSNEKG ESTR_MOUSE 157 1 NSDNRRQNGRERLSSSSEKG ESTR_RAT 158 1 SSDNRRHSIRERMSSTNEKG ESTR_CHICK 147 1 FINAL MOTIF SETS OESTROGENR1 Length of motif = 19 Motif number = 1 Oestrogen receptor motif I - 3 PCODE ST INT HTKASGMALLHQIQGNELE A8KAF4_HUMAN 6 6 HTKASGMALLHQIQGNELE Q5T5H7_HUMAN 6 6 HTKASGMALLHQIQGNELE Q14268_HUMAN 6 6 HTKASGMALLHQIQGNELE Q14267_HUMAN 6 6 HTKASGMALLHQIQGNELE ESR1_HUMAN 6 6 HTKASGMALLHQIQGNELE B6ZGU3_HUMAN 6 6 HTKASGMALLHQIQGNELE B6CK22_TRAOB 6 6 HTKASGMALLHQIQGNELE B6CK20_CERAE 6 6 HTKASGMALLHQIQGNELE B6CK18_HYLLA 6 6 HTKASGMALLHQIQGNELE B6CK17_PONPY 6 6 HTKASGMALLHQIQGNELE B6CK16_9PRIM 6 6 HTKASGMALLHQIQGNELE B6CK15_PANPA 6 6 HTKASGMALLHQIQGNELE B6CK21_COLGU 6 6 HTKASGMALLHQIQGNELE B6CK19_PAPAN 6 6 HTKASGMALLHQIQANELE A2TEV4_PIG 6 6 HTKASGMALLHQIQANELE ESR1_PIG 6 6 HTKASGMALLHQIQGNELE B6CK23_ATEPA 6 6 HTKASGMALLHQIQGNELE B6CK24_CEBAP 6 6 HTKASGMALLHQIQGNELE ESR1_FELCA 6 6 HTKASGMALLHQIQANELE ESR1_BOVIN 6 6 HTKASGMALLHQIQGNELE B3VQI7_MOUSE 6 6 HTKASGMALLHQIQGNELE Q3UT58_MOUSE 6 6 HTKASGMALLHQIQGNELE ESR1_MOUSE 6 6 HTKASGMALLHQIQGNELE ESR1_MESAU 6 6 HTKASGMALLHQIQGNELE D0FYH4_RAT 6 6 HTKASGMALLHQIQGNELE ESR1_RAT 6 6 HTKASGMALLHQIQGNELE ESR1_HORSE 6 6 HTKTSGVALLHQIQGTELE A8QZK3_9SAUR 6 6 HTKTSGVALLHQIQGTELE B6E1V9_9SAUR 6 6 HTKASGVTLLHQIQGTELE ESR1_CHICK 6 6 HTKTSGVTLLHQIQGTELE B6ZK18_9FALC 4 4 HTKTSGVTLLHQIQGTELE B6ZK19_TORTR 4 4 HTKASGMALLHQIQGNELE Q1EDB6_MICOH 6 6 HTKASGVTLLHQIQGTELE Q8AYH0_COTJA 6 6 HTKNSGVALLHQIQSTELE B6CZ21_9SAUR 6 6 HTKTSGVTLLHQIQGTELE Q3LGB2_CRONI 6 6 HTKTSGVTLLHQIQGTELE ESR1_TAEGU 4 4 HTKTSGVTLLHQIQGTELE Q765N7_ALLMI 6 6 HNKTTGVTLLHQIQSSELE B2NIY0_XENLA 6 6 HNKTTGVTLLHQIQSSELE B2NIY1_XENLA 6 6 HTKTSGVTLLHQIQGTELE Q8UWB0_CAICR 6 6 HNKTTGVTLLHQIQSSELE Q25C14_XENTR 6 6 PNKTTGVTFLHQIQSSELE ESR1_XENLA 6 6 PNKTTGVTFLHQIQSSELE Q6W5G7_XENLA 6 6 HSKIPGVTLLHQIQATELE Q0KKA1_9AMPH 4 4 HSKTPGVALLHQIQATELE A8VFJ8_PLEWA 4 4 OESTROGENR2 Length of motif = 18 Motif number = 2 Oestrogen receptor motif II - 3 PCODE ST INT LNRPQLKIPLERPLGEVY A8KAF4_HUMAN 26 1 LNRPQLKIPLERPLGEVY Q5T5H7_HUMAN 26 1 LNRPQLKIPLERPLGEVY Q14268_HUMAN 26 1 LNRPQLKIPLERPLGEVY Q14267_HUMAN 26 1 LNRPQLKIPLERPLGEVY ESR1_HUMAN 26 1 LNRPQLKIPLERPLGEVY B6ZGU3_HUMAN 26 1 LNRPQLKIPLERPLGEVY B6CK22_TRAOB 26 1 LNRPQLKIPLERPLGEVY B6CK20_CERAE 26 1 LNRPQLKIPLERPLGEVY B6CK18_HYLLA 26 1 LNRPQLKIPLERPLGEVY B6CK17_PONPY 26 1 LNRPQLKIPLERPLGEVY B6CK16_9PRIM 26 1 LNRPQLKIPLERPLGEVY B6CK15_PANPA 26 1 LNRPQLKIPLERPLGEVY B6CK21_COLGU 26 1 LNRPQLKIPLERPLGEVY B6CK19_PAPAN 26 1 LNRPQLKIPLERPLGEVY A2TEV4_PIG 26 1 LNRPQLKIPLERPLGEVY ESR1_PIG 26 1 LNRPQLKIPLERPLGEVY B6CK23_ATEPA 26 1 LNRPQLKIPLERPLGEVY B6CK24_CEBAP 26 1 LNRPQLKIPLERPLGEVY ESR1_FELCA 26 1 LNRPQLKIPLERPLGEVY ESR1_BOVIN 26 1 LNRPQLKMPMERALGEVY B3VQI7_MOUSE 26 1 LNRPQLKMPMERALGEVY Q3UT58_MOUSE 26 1 LNRPQLKMPMERALGEVY ESR1_MOUSE 26 1 LSRPQLKMPLERALSEVY ESR1_MESAU 26 1 LNRPQLKMPMERALGEVY D0FYH4_RAT 26 1 LNRPQLKMPMERALGEVY ESR1_RAT 26 1 LNLPQFKIPLERPLGEVY ESR1_HORSE 26 1 LSRPQLKIPLDRSLSEMY A8QZK3_9SAUR 26 1 LSRPQLKIPLDRSLSEMY B6E1V9_9SAUR 26 1 LSRPQLKIPLERSLSDMY ESR1_CHICK 26 1 LSRPQLKIPLERSLSDMY B6ZK18_9FALC 24 1 LSRPQLKIPLERSLSDMY B6ZK19_TORTR 24 1 LNRPQLKMPLERALGEVY Q1EDB6_MICOH 26 1 LSRPQLKIPLERSLSDMY Q8AYH0_COTJA 26 1 LSRPQLKIPLDRSLSEMY B6CZ21_9SAUR 26 1 LSRPQLKIPLDRSLTEMY Q3LGB2_CRONI 26 1 LSRPQLKIPLERSLSDMY ESR1_TAEGU 24 1 LSRPQLKIPLDRSLSEMY Q765N7_ALLMI 26 1 LSRPPLKIPLERPLGEMC B2NIY0_XENLA 26 1 LSRPPLKIPLERPLGEMC B2NIY1_XENLA 26 1 LSRPQLKIPLDRSLSEMY Q8UWB0_CAICR 26 1 LSRPPLKIPLERPLSEMY Q25C14_XENTR 26 1 LTRPPLKISLERPLGEMY ESR1_XENLA 26 1 LTRPPLKISLERPLGEMY Q6W5G7_XENLA 26 1 LGRPALKIPLDRPLSDMY Q0KKA1_9AMPH 24 1 RGRPPLKLPLDRSLGEMY A8VFJ8_PLEWA 24 1 OESTROGENR3 Length of motif = 18 Motif number = 3 Oestrogen receptor motif III - 3 PCODE ST INT DSSKPAVYNYPEGAAYEF A8KAF4_HUMAN 45 1 DSSKPAVYNYPEGAAYEF Q5T5H7_HUMAN 45 1 DSSKPAVYNYPEGAAYEF Q14268_HUMAN 45 1 DSSKPAVYNYPEGAAYEF Q14267_HUMAN 45 1 DSSKPAVYNYPEGAAYEF ESR1_HUMAN 45 1 DSSKPAVYNYPEGAAYEF B6ZGU3_HUMAN 45 1 DSSKPAVYNYPEGAAYEF B6CK22_TRAOB 45 1 DSSKPAVYNYPEGAAYEF B6CK20_CERAE 45 1 DSSKPAVYNYPEGAAYEF B6CK18_HYLLA 45 1 DSSKPAVYNYPEGAAYEF B6CK17_PONPY 45 1 DSSKPAVYNYPEGAAYEF B6CK16_9PRIM 45 1 NSSKPAVYNYPEGAAYEF B6CK15_PANPA 45 1 DSSKPAVYNYPEGAAYEF B6CK21_COLGU 45 1 DSSKPAVYSYPEGAAYEF B6CK19_PAPAN 45 1 DSSKPAVYNYPEGAAYDF A2TEV4_PIG 45 1 DSSKPAVYNYPEGAAYDF ESR1_PIG 45 1 DSSKPAVYNYPEGAAYEF B6CK23_ATEPA 45 1 DSSKPAVYNYPEGAAYEF B6CK24_CEBAP 45 1 DGSKPAVYNYPEGAAYDF ESR1_FELCA 45 1 DSSKPAVYNYPEGAAYDF ESR1_BOVIN 45 1 DNSKPTVFNYPEGAAYEF B3VQI7_MOUSE 45 1 DNSKPTVFNYPEGAAYEF Q3UT58_MOUSE 45 1 DNSKPTVFNYPEGAAYEF ESR1_MOUSE 45 1 DSSKPAMFNYPEGAAYEF ESR1_MESAU 45 1 DNSKPAVFNYPEGAAYEF D0FYH4_RAT 45 1 DNSKPAVFNYPEGAAYEF ESR1_RAT 45 1 ESSKPPVYDYPEGAAYDF ESR1_HORSE 45 1 ESNKTGVFNYPEGTTYDF A8QZK3_9SAUR 45 1 ESNKTGVFNYPEGTTYDF B6E1V9_9SAUR 45 1 ESNKTGVFNYPEGATYDF ESR1_CHICK 45 1 ESNKTGVFNYPEGATYDF B6ZK18_9FALC 43 1 ESNKTGVFNYPEGATYDF B6ZK19_TORTR 43 1 DGSKPAVFNYPESAAYEF Q1EDB6_MICOH 45 1 ESNKTGVFNYPEGATYDF Q8AYH0_COTJA 45 1 ESNKTGVFNYPEGTTYDF B6CZ21_9SAUR 45 1 ESNKTGIFNYPEGTTYDF Q3LGB2_CRONI 45 1 ETNKTGVFNYPEGATYDF ESR1_TAEGU 43 1 ESNKTGIFNYPEGTTYDF Q765N7_ALLMI 45 1 ENNRTGIFNYPEGTTYDF B2NIY0_XENLA 45 1 ENNRTGIFNYPEGTTYDF B2NIY1_XENLA 45 1 ENNKTGIFNYPEGTTYDF Q8UWB0_CAICR 45 1 ENNRTGIFNYPEGTTYDF Q25C14_XENTR 45 1 ENNRTGIFNYPEGTTYDF ESR1_XENLA 45 1 ENNRTGIFNYPEGTTYDF Q6W5G7_XENLA 45 1 ENNRTGIFNYSEGATFDF Q0KKA1_9AMPH 43 1 ENSRTGIFSYPEGTTYEF A8VFJ8_PLEWA 43 1 OESTROGENR4 Length of motif = 16 Motif number = 4 Oestrogen receptor motif IV - 3 PCODE ST INT AQVYGQTGLPYGPGSE A8KAF4_HUMAN 70 7 AQVYGQTGLPYGPGSE Q5T5H7_HUMAN 70 7 AQVYGQTGLPYGPGSE Q14268_HUMAN 70 7 AQVYGQTGLPYGPGSE Q14267_HUMAN 70 7 AQVYGQTGLPYGPGSE ESR1_HUMAN 70 7 AQVYGQTGLPYGPGSE B6ZGU3_HUMAN 70 7 AQVYGQTGLPYGPGSE B6CK22_TRAOB 70 7 AQVYGQTGLPYGPGSE B6CK20_CERAE 70 7 AQVYGQTGLPYGPGSE B6CK18_HYLLA 70 7 AQVYGQTGLPYGPGSE B6CK17_PONPY 70 7 AQVYGQTGLPYGPGSE B6CK16_9PRIM 70 7 AQVYGQTGLPYGPGSE B6CK15_PANPA 70 7 AQVYGQTGLPYGPGSE B6CK21_COLGU 70 7 AQVYGQTGLPYGPGSE B6CK19_PAPAN 70 7 APVYGQSGLAYGPGSE A2TEV4_PIG 70 7 APVYGQSGLAYGPGSE ESR1_PIG 70 7 AQVYGQSGLPYGPGSE B6CK23_ATEPA 70 7 AQVYGQSGLPYGPGSE B6CK24_CEBAP 70 7 APVYGQSGLAYGSGSE ESR1_FELCA 70 7 APVYGQSGLPYGPGSE ESR1_BOVIN 70 7 APVYGQSGIAYGPGSE B3VQI7_MOUSE 71 8 APVYGQSGIAYGPGSE Q3UT58_MOUSE 74 11 APVYGQSGIAYGPGSE ESR1_MOUSE 74 11 APVYGQTGIAYGSGSE ESR1_MESAU 69 6 APVYGQSSITYGPGSE D0FYH4_RAT 75 12 APVYGQSSITYGPGSE ESR1_RAT 75 12 ASVYGQSGLAYGPGSE ESR1_HORSE 70 7 APVYSSTSLSYAPASE A8QZK3_9SAUR 66 3 APVYSSTSLSYAPASE B6E1V9_9SAUR 66 3 APVYGSTTLSYAPTSE ESR1_CHICK 66 3 APVYSSTTLSYAPTSE B6ZK18_9FALC 64 3 APVYSSTTLSYAPTSE B6ZK19_TORTR 64 3 APVYGQSGIAYGPGSE Q1EDB6_MICOH 72 9 APVYGSTTLSYAPTSE Q8AYH0_COTJA 66 3 APVYSSTSLSYAPASE B6CZ21_9SAUR 66 3 APVYSSTSLSYAPTSE Q3LGB2_CRONI 66 3 APVYSSTTLSYAPTSE ESR1_TAEGU 64 3 APVYSSTSLSYAPTSE Q765N7_ALLMI 66 3 APVYSSASLSYAPSSE B2NIY0_XENLA 67 4 APVYSSASLSYAPSSE B2NIY1_XENLA 67 4 APVYSSTSLSYAPTSE Q8UWB0_CAICR 66 3 APVYSSASLSYAASSE Q25C14_XENTR 67 4 APVYSSASLSYAASSE ESR1_XENLA 67 4 APVYSSASLSYAASSE Q6W5G7_XENLA 67 4 APIYSSASLNYAASSE Q0KKA1_9AMPH 65 4 APIYSSASLSYAASSD A8VFJ8_PLEWA 65 4 OESTROGENR5 Length of motif = 15 Motif number = 5 Oestrogen receptor motif V - 3 PCODE ST INT FPPLNSVSPSPLMLL A8KAF4_HUMAN 97 11 FPPLNSVSPSPLMLL Q5T5H7_HUMAN 97 11 FPPLNSVSPSPLMLL Q14268_HUMAN 97 11 FPPLNSVSPSPLMLL Q14267_HUMAN 97 11 FPPLNSVSPSPLMLL ESR1_HUMAN 97 11 FPPLNSVSPSPLMLL B6ZGU3_HUMAN 97 11 FPPLNSVSPSPLMLL B6CK22_TRAOB 97 11 FPPLNSVSPSPLMLL B6CK20_CERAE 97 11 FPPLNSVSPSPLMLL B6CK18_HYLLA 97 11 FPPLNSVSPSPLMLL B6CK17_PONPY 97 11 FPPLNSVSPSPLMLL B6CK16_9PRIM 97 11 FPPLNSVSPSPLMLL B6CK15_PANPA 97 11 FPPLNSVSPSPLMLL B6CK21_COLGU 97 11 FPPLNSVSPSPLMLL B6CK19_PAPAN 97 11 FQPLNSVSPSPLVLL A2TEV4_PIG 97 11 FQPLNSVSPSPLVLL ESR1_PIG 97 11 FPPLNSVSPSPLMLL B6CK23_ATEPA 97 11 FPTLNSVSPSQLMLL B6CK24_CEBAP 97 11 FPPLNSVSPSPLVLL ESR1_FELCA 97 11 FPPLNSVSPSPLVLL ESR1_BOVIN 97 11 FPQLNSVSPSPLMLL B3VQI7_MOUSE 98 11 FPQLNSVSPSPLMLL Q3UT58_MOUSE 101 11 FPQLNSVSPSPLMLL ESR1_MOUSE 101 11 FPQLNSVSPSPLMLL ESR1_MESAU 96 11 FPQLNSVSPSPLMLL D0FYH4_RAT 102 11 FPQLNSVSPSPLMLL ESR1_RAT 102 11 FPPLNSVSPSQLMLL ESR1_HORSE 97 11 FHSLNNVPPSPVVFL A8QZK3_9SAUR 91 9 FHSLNNVPPSPVVFL B6E1V9_9SAUR 91 9 FHSLNNVPPSPVVFL ESR1_CHICK 91 9 FHSLNNVPPSPVVFL B6ZK18_9FALC 89 9 FHSLNNVPPSPVVFL B6ZK19_TORTR 89 9 FPQLNSVSPSPLMLL Q1EDB6_MICOH 99 11 FHSLNNVPPSPVVFL Q8AYH0_COTJA 91 9 FHSLNNVPPSPMVFL B6CZ21_9SAUR 91 9 FHSLNNVPPSPVVFL Q3LGB2_CRONI 91 9 FHSLNSVPPSPVVFL ESR1_TAEGU 89 9 FHSLNNVPPSPVVFL Q765N7_ALLMI 91 9 LHTLNNVPPSPVVFL B2NIY0_XENLA 92 9 LHTLNNVPPSPVVFL B2NIY1_XENLA 92 9 FHSLNNVPPSPVVFL Q8UWB0_CAICR 91 9 LHTLNNVPPSPVVFL Q25C14_XENTR 92 9 LHTLNNVPPSPVVFL ESR1_XENLA 92 9 LHTLNNVPPSPVVFL Q6W5G7_XENLA 92 9 LHSLNSVPPSPVVFL Q0KKA1_9AMPH 90 9 LHSLNSVPPSPVVFL A8VFJ8_PLEWA 90 9 OESTROGENR6 Length of motif = 17 Motif number = 6 Oestrogen receptor motif VI - 3 PCODE ST INT PQLSPFLQPHGQQVPYY A8KAF4_HUMAN 115 3 PQLSPFLQPHGQQVPYY Q5T5H7_HUMAN 115 3 PQLSPFLQPHGQQVPYY Q14268_HUMAN 115 3 PQLSPFLQPHGQQVPYY Q14267_HUMAN 115 3 PQLSPFLQPHGQQVPYY ESR1_HUMAN 115 3 PQLSPFLQPHGQQVPYY B6ZGU3_HUMAN 115 3 PQLSPFLQPHGQQVPYY B6CK22_TRAOB 115 3 PQLSPFLQPHGQQVPYY B6CK20_CERAE 115 3 PQLSPFLQPHGQQVPYY B6CK18_HYLLA 115 3 PQLSPFLQPHGQQVPYY B6CK17_PONPY 115 3 PQLSPFLQPHGQQVPYY B6CK16_9PRIM 115 3 PQLSPFLQPHGQQVPYY B6CK15_PANPA 115 3 PQLSPFLQPHGQQVPYY B6CK21_COLGU 115 3 PQLSPFLQPHGQQVPYY B6CK19_PAPAN 115 3 PQLSPFLHPHGQQVPYY A2TEV4_PIG 115 3 PQLSPFLHPHGQQVPYY ESR1_PIG 115 3 PQLSPFLQPHGQQVPYY B6CK23_ATEPA 115 3 PQLSPFLQPHGQQVPYY B6CK24_CEBAP 115 3 PQLSPFLHPHGQQVPYY ESR1_FELCA 115 3 QPLSPFLHPHGQQVPYY ESR1_BOVIN 116 4 PQLSPFLHPHGQQVPYY B3VQI7_MOUSE 116 3 PQLSPFLHPHGQQVPYY Q3UT58_MOUSE 119 3 PQLSPFLHPHGQQVPYY ESR1_MOUSE 119 3 PQLSPFLHPHGQQVPYY ESR1_MESAU 115 4 PQLSPFLHPHGHQVPYY D0FYH4_RAT 120 3 PHVSPFLHPHGHQVPYY ESR1_RAT 120 3 PQLSPYLHPPGQQVPYY ESR1_HORSE 115 3 PQLSPFIHHHSQQVPYY A8QZK3_9SAUR 109 3 PQLSPFIHHHSQQVPYY B6E1V9_9SAUR 109 3 PQLSPFIHHHSQQVPYY ESR1_CHICK 109 3 PQLSPFIHHHSQQVPYY B6ZK18_9FALC 107 3 PQLSPFIHHHSQQVPYY B6ZK19_TORTR 107 3 PQLSPFLHPHGQQVPYY Q1EDB6_MICOH 118 4 PQLSPFIHHHSQQVPYY Q8AYH0_COTJA 109 3 PQLSPFIHHHSQQVPYY B6CZ21_9SAUR 109 3 PQLSPFIHHHSQQVPYY Q3LGB2_CRONI 109 3 PHWSPFIHHHSQQVPYY ESR1_TAEGU 107 3 PQLSPFIHHHSQQVPYY Q765N7_ALLMI 109 3 PQLSPFIHHHGQQVPYY B2NIY0_XENLA 109 2 PQLSPFIHHHGQQVPYY B2NIY1_XENLA 109 2 PQLSPFVHHHSQQVPYY Q8UWB0_CAICR 109 3 PQLSPFIHHHGQQVPYY Q25C14_XENTR 109 2 PQLSPFIHHHGQQVPYY ESR1_XENLA 110 3 PQLSPFIHHHGQQVPYY Q6W5G7_XENLA 109 2 PQLSPFIHHHGQQVPYY Q0KKA1_9AMPH 108 3 PQLSPFIHHHGQQVPYY A8VFJ8_PLEWA 108 3 OESTROGENR7 Length of motif = 20 Motif number = 7 Oestrogen receptor motif VII - 3 PCODE ST INT LENEPSGYTVREAGPPAFYR A8KAF4_HUMAN 132 0 LENEPSGYTVREAGPPAFYR Q5T5H7_HUMAN 132 0 LENEPSGYTVREAGPPAFYR Q14268_HUMAN 132 0 LENEPSGYTVREAGPPAFYR Q14267_HUMAN 132 0 LENEPSGYTVREAGPPAFYR ESR1_HUMAN 132 0 LENEPSGYTVREAGPPAFYR B6ZGU3_HUMAN 132 0 LENEPSGYTVREAGPPAFYR B6CK22_TRAOB 132 0 LENEPSGYTVREAGPPAFYR B6CK20_CERAE 132 0 LENEPSGYTVREAGPPAFYR B6CK18_HYLLA 132 0 LENEPSGYTVREAGPPAFYR B6CK17_PONPY 132 0 LENEPSGYTVREAGPPAFYR B6CK16_9PRIM 132 0 LENEPSGYTVREAGPPAFYR B6CK15_PANPA 132 0 LENEPSGYTVREAGQPAFYR B6CK21_COLGU 132 0 LENEPSGYTVREAGPPAFYR B6CK19_PAPAN 132 0 LENEPSGYAVREAGPPAFYR A2TEV4_PIG 132 0 LENEPSGYAVREAGPPAFYR ESR1_PIG 132 0 LENEPSGYTVREAGQPAFYR B6CK23_ATEPA 132 0 LENEPSGYTVREAGPPAFYR B6CK24_CEBAP 132 0 LENEPSGYAVREAGPPAFYR ESR1_FELCA 132 0 LENESSGYAVREAGPPAYYR ESR1_BOVIN 133 0 LENEPSAYAVRDTGPPAFYR B3VQI7_MOUSE 133 0 LENEPSAYAVRDTGPPAFYR Q3UT58_MOUSE 136 0 LENEPSAYAVRDTGPPAFYR ESR1_MOUSE 136 0 LENEPSAYAVRDSGPPAFYR ESR1_MESAU 132 0 LENEPSAYAVRDTGPPAFYR D0FYH4_RAT 137 0 LENEPSAYAVRDTGPPAFYR ESR1_RAT 137 0 LENEPSGYSVCEAGPQAFYR ESR1_HORSE 132 0 LENDQSSFGMREAGPPAFYR A8QZK3_9SAUR 126 0 LENDQSSFGMREAGPPAFYR B6E1V9_9SAUR 126 0 LENEQGSFGMREAAPPAFYR ESR1_CHICK 126 0 LENEQGSFGMREAAPPAFYR B6ZK18_9FALC 124 0 LENEQGSFGMREAAPPAFYR B6ZK19_TORTR 124 0 ENEPSAYAAVRDPGPPAFYR Q1EDB6_MICOH 136 1 LENEQGSFGMRETAPPAFYR Q8AYH0_COTJA 126 0 LENDQSSFGMREAGPPTFYR B6CZ21_9SAUR 126 0 LENDQSGFGMREAAPPTFYR Q3LGB2_CRONI 126 0 LENDQGSFGMREAAPPAFYR ESR1_TAEGU 124 0 LENDQSGFGMREAAPSTFYR Q765N7_ALLMI 126 0 LESEQGTFAVREAPPPTFYR B2NIY0_XENLA 126 0 LESEQGTFAVREAPPPTFYR B2NIY1_XENLA 126 0 LENDQSGFGMREAASSTFYR Q8UWB0_CAICR 126 0 LESEQGTFAVREAAPPTFYR Q25C14_XENTR 126 0 LESEQGTFAVREAAPPTFYR ESR1_XENLA 127 0 LESEQGTFAVREAAPPTFYR Q6W5G7_XENLA 126 0 LENEQGTYGAREAAPPAFYR Q0KKA1_9AMPH 125 0 LDSDQGSFGAREAAPPAFYR A8VFJ8_PLEWA 125 0 OESTROGENR8 Length of motif = 20 Motif number = 8 Oestrogen receptor motif VIII - 3 PCODE ST INT NSDNRRQGGRERLASTNDKG A8KAF4_HUMAN 153 1 NSDNRRQGGRERLASTNDKG Q5T5H7_HUMAN 153 1 NSDNRRQGGRERLASTNDKG Q14268_HUMAN 153 1 NSDNRRQGGRERLASTNDKG Q14267_HUMAN 153 1 NSDNRRQGGRERLASTNDKG ESR1_HUMAN 153 1 NSDNRRQGGRERLASTNDKG B6ZGU3_HUMAN 153 1 NSDNRRQGGRERLASTNDKG B6CK22_TRAOB 153 1 NSDNRRQGGRERLASTNDKG B6CK20_CERAE 153 1 NSDNRRQGGRERLASTNDKG B6CK18_HYLLA 153 1 NSDNRRQGGRERLASTNDKG B6CK17_PONPY 153 1 NSDNRRQGGRERLASTNDKG B6CK16_9PRIM 153 1 NSDNRRQGGRERLASTNDKG B6CK15_PANPA 153 1 NSDNRRQGGRERLASTNDKG B6CK21_COLGU 153 1 NSDNRRQGGRERLASTNDKG B6CK19_PAPAN 153 1 NSDNRRQGGRERLASTSDKG A2TEV4_PIG 153 1 NSDNRRQGGRERLASTSDKG ESR1_PIG 153 1 NSDNRRQGGRERLPSTNDKG B6CK23_ATEPA 153 1 NSDNRRQGGRERLASTNDKG B6CK24_CEBAP 153 1 TSDNRRQSGRERLASTGDKG ESR1_FELCA 153 1 NSDNRRQGGRERLASTSDKG ESR1_BOVIN 154 1 NSDNRRQNGRERLSSSNEKG B3VQI7_MOUSE 154 1 NSDNRRQNGRERLSSSNEKG Q3UT58_MOUSE 157 1 NSDNRRQNGRERLSSSNEKG ESR1_MOUSE 157 1 NSDNRRQSGRERLSSSSEKG ESR1_MESAU 153 1 NSDNRRQNGRERLSSSSEKG D0FYH4_RAT 158 1 NSDNRRQNGRERLSSSSEKG ESR1_RAT 158 1 NADNRRQGGRERLASSGDKG ESR1_HORSE 153 1 SSDNRRQGSRERMSSTSEKG A8QZK3_9SAUR 147 1 SSDNRRQGSRERMSSTSEKG B6E1V9_9SAUR 147 1 SSDNRRHSIRERMSSTNEKG ESR1_CHICK 147 1 SSDNRRHSIRERMSSTNDKG B6ZK18_9FALC 145 1 SSDNRRHSIRERMSSTNDKG B6ZK19_TORTR 145 1 NSDNRRQSGRERLSNNGEKG Q1EDB6_MICOH 157 1 SSDNRRHSIRERMSSASEKG Q8AYH0_COTJA 147 1 SSDNRRQGSRERMSSTSEKG B6CZ21_9SAUR 147 1 GADNRRQSGRERMSSTSEKA Q3LGB2_CRONI 147 1 NSDNRRHSIRERMSSANEKG ESR1_TAEGU 145 1 GADSRRQSGRERMSSTSEKT Q765N7_ALLMI 147 1 SSDNRRQSGRERMSSANDKG B2NIY0_XENLA 147 1 SSDNRRQSGRERMSSANDKG B2NIY1_XENLA 147 1 SADSRHQSGRERMSSTSEKA Q8UWB0_CAICR 147 1 SSDNRRQSGRERMTSANDKG Q25C14_XENTR 147 1 SSDNRRQSGRERMSSANDKG ESR1_XENLA 148 1 SSDNRRQSGRERMSSANDKG Q6W5G7_XENLA 147 1 SSDLRRQTGRERISTASEKG Q0KKA1_9AMPH 146 1 SSDLRRQPGRERPSTASEKG A8VFJ8_PLEWA 146 1

User query: Display/Full Code "OESTROGENR"