1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151       161       171       181       191       201       211       221       231       241       251       261       271       281       291       301       311       321       331       341       351       361       371       381       391       401       411       421       431       441     
                       |---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|-------
 WN2B_MOUSE            ------------MLKLQGEDEAAQLAPRRARVPVPRPTAPDVSPSSARLGLACLLLLLLLTLPARVDTSWWYIGALG--------------ARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHT-VFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHD------------------QRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRL--KDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGANFTAARQ----------GYRHATRTDLVYFDNSPDYCVLDKASGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFH--WCCAVRCKECRNTVDVHTCKAPKKAEWLDQT  
 Q9PWH1                -----------------------MKSFCSEVVAKSRLGLKQWGWCGWTPMGSAWKKWISEQRSSLELWDVGSLAIGHQYSSL-------GTQPILCGSIPGLVPKQLRFCRNYVEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDSLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSATICGCDTRHKGSPGE---------------------GWKWGGCSEDVEFGSMVSREFADARENRP---DARSAMNRHNNEAGRTSIIELMHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVET----LRPKYNFFKAPTEKDLVYYENSPNFCEPNPETGSFGTRDRICNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFH--WCCYVRCQECIRVYDVHTCK  
 WNT2_BRARE            -------------------------------------------MNFLPNGICFYLSVAICWFSSRVDASWWYMGTLG--------------SQVMCDNIPGLINKQRQLCRQHPKVMQAIGAGIKNWIGECQHQFRTHRWNCNTMAREHN-LFGRLLHRSSREAAFVYAISSAGMVYTLTRACSQGELENCSCDPGKKGSSRD------------------AKGAFDWGGCSDHVDHAIKFTQVFIDAKERKE--RDARALMNLHNNRAGRKAVKRFMNLECKCHGVSGSCNVRTCWLAMADFRQTGDYLRKKYNNAIQVVMNQYGTGFTSAYR----------MLKRPNKNDLVYFEDSPDYCIWDHESGSVGTGGRVCNRTSRGTDSCEVMCCGRGYDTSRVSRTTKCECKFQ--WCCAVHCRDCQEEVDVHTCKTQS  
 WNT4_CHICK            ---------------------------------------------MSPEYFLRSLLLIILATFSANASNWLYLAKLSSVGSI--------SEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCS--TLDTLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELDKCGCDRTVQGGSPQ---------------------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSNRALMNLHNNEAGRKAILNNMRVECKCHGVSGSCEFKTCWKAMPPFRKVGNVLKEKFDGATEVEQ------SEIGSTKVLVPKNSQFKPHTDE--DLVYLDSSPDFCDHDLKNGVLGTSGRQCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKFH--WCCSVKCKPCHRVVEIHTCR  
 WNT3_HUMAN            --------------------------------------------MEPHLLGLLLGLLLGGTRVLAGYPIWWSLALGQQYTSL-------GSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGE---------------------GWKWGGCSEDADFGVLVSREFADARENRP---DARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVET----LRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFH--WCCYVSCQECIRIYDVHTCK  
 WNT1_MOUSE            ------------------------------------MGLWALLPSWVSTTLLLALTALPAALAANSSGRWWGIVNIASSTNLL--TDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPH--LFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGP---------------------DWHWGGCSDNIDFGRLFGREFVDSGEKG---RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRAS-RAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFH--WCCHVSCRNCTHTRVLHECL  
 WNT4_XENLA            ---------------------------------------------MTPEYFLRSLLMMILAVFSANASNWLYLAKLSSVGSI--------SEEETCEKLKGPIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCS--TLDTLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGDLEKCGCDRTVHGVSPQ---------------------GFQWSGCSDNILYGVAFSQSFVDVRERSKGGSSSRALMNLHNNEAGRKAILNNMRVECKCHGVSGSCEVKTCWKAMPTFRKVGNVLKEKFDGATEVEQ------KKIGSTKVLVPKNSQFKPHTDE--DLVYLDSSPDFCDHDLKNGVLGTTGRQCNKTSKAIDGCELMCCGRGFHTEEVEIVERCSCKFH--WCCFVKCKQCHKVVEMHTCR  
 WNT1_HUMAN            ------------------------------------MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLL--TDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPH--LFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGP---------------------DWHWGGCSDNIDFGRLFGREFVDSGEKG---RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRAS-RAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFH--WCCHVSCRNCTHTRVLHECL  
 WN3A_XENLA            -----------------------------------------------MGCFGYLLLIIGLHQVLATYPIWWSLAVGQQYSSL-------GTQPIPCGTIPGLVAKQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVNDNLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSATICGCDTHHKGPPGE---------------------GWKWGGCSEDMDFGSMVSREFADARENRP---DARSAMNRHNNEAGRTSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVET----LRPKYTFFKPPIERDLIYYESSPNFCEPNPETGSFGTRDRECNVTSHGIDGCDLLCCGRGQNTRTEKRKEKCHCIFH--WCCYVSCQECMRVYDVHTCK  
 WNT6_MOUSE            --------------------------------------------MLPPVPSRLGLLLLLL-CPAHVDGLWWAVGSPLVM-----------DPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRECQFQFRFRRWNCS----SHSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAPPRPSGLLGTPGPPGPTGSPDASAAWEWGGCGDDVDFGDEKSRLFMDAQHKRG-RGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALSTCWQKLPPFREVGARLLERFHGASRVMG--------TNDGKALLPAVRTLKPPGRA--DLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFH--WCCVVQCHRCRVRKELSLCL  
 WNT4_RAT              ---------------------------------------------MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSI--------SEEETCEKLKGLIQRQVQMCKRNLEVMDSVRHGAQLAIEECQYQFRNRRWNCS--TLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGDLEKCGCDRTVHGVSPQ---------------------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEP------RRVGSSRALVPRNAQFKPHTDE--DLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAHVELAERCGCRFH--WCCFVKCRQCQRLVEMHTCR  
 WNT3_MOUSE            --------------------------------------------MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSL-------ASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGE---------------------GWKWGGCSEDADFGVLVSREFADARENRP---DARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVET----LRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFH--WCCYVSCQECIRIYDVHTCK  
 WNT2_HUMAN            -------------------------------------------MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATG------------GSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHS-LFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKD------------------SKGIFDWGGCSDNIDYGIKFARAFVDAKERKG--KDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANE----------RFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFH--WCCAVRCQDCLEALDVHTCKAPKNADWTTAT  
 WNT6_HUMAN            --------------------------------------------MLPPLPSRLGLLLLLLLCPAHVGGLWWAVGSPLVM-----------DPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRECQFQFRFRRWNCS----SHSKAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAPPRPSGLPGTPGPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRLFMDARHKRG-RGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMG--------TNDGKALLPAVRTLKPPGRA--DLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFH--WCCVVQCHRCRVRKELSLCL  
 WNT4_DROME            MGSHPHGHALAGLAKLGIIVAGGQGLPGNLGYGGTMLNGGGVGGAAGMGLRIGSNTNNMDMQQGLYNEHFISEHTVMAVFTSQ-------GQVGGPCRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQ---------------------DFQWGGCNDNLKHGKRVTRSFLDLR---GGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIAKAP-NQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--------TKDRQCLHP----DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRVENKYFCK  
 WNT4_MOUSE            ---------------------------------------------MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSI--------SEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCS--TLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQ---------------------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEP------RRVGSSRALVPRNAQFKPHTDE--DLVYLEPSPDFCEQDIRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCGCRFH--WCCFVKCRQCQRLVEMHTCR  
 P79752                ------------------------------------MRNLALLLG-VKAACILLVSSLTGTGAVNNSGRWWGIVNVASSSNLL--TNSKNVQLVLDPSLALLSRRQRRLIRQNPGILHAIAAGLHAAIKECKWQFRNRRWNCPTTHSPA--VFGKIVNRGCRETAFVFAIMSAGVTHAVARSCSEGAIEFCTCDYRRRGPGGP---------------------DWHWGGCSDNVEFGRMFSREFVDSSERG---RDLRYLTNLHNNEAGRMTVSSEMRQECKCHGMSGSCTVRTCWMRLPSFRMVGDFLKDRFDGASRVVYANKGSNRASHRAHPRHLEPENPAHKPPSSMDLVYFEKSPNFCSYSGKTGTLGTSGRACNSTSPGLDGCELLCCGRGFKTRTESMTERCHCTFH--WCCHVSCLNCTSTRTLHQCV  
 Q9VM29                MGSHPHGHALAGLAKLGIIVPGGQGLPGNLGYGGTMLNGGGVGGAAGMGLGIGSNTNNMDMQQGLYNEHFISEHTVMAVFTSQ-------GQVGGPCRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQ---------------------DFQWGGCNDNLKHGKRVTRSFLDLR---GGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAP-NQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--------TKDRQCLHP----DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK  
 WNT1_AMBME            ------------------------------------MRPMTFIVG-LKTLWILAFSSLSNTLAVNNSGRWWGVVNVVTSTNLL--TDTKNVQLVLDPSLQLLSRKQRKLIRQNPGILHSINSGLQSAMKECKWQFRSRRWNCPTTGGDN--IFGKIVNKGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGT---------------------DWHWGGCSDNIDFGRVFGREFVDSSERG---RDLRYLMNRHNNEAGRMTVFSEMKQECKCHGMSGSCAVRTCWMRLPTFRAVGDFLKDRFDGASRVIYGNKGSNRAS-RVQTHHLEPENPTHKPPSPQDLVYFEKSPNFCTYNGKTGTSGTSGRVCNSSSLGLDGCELLCCGRGYRTKTQRVTERCHCTFH--WCCHVSCLNCTNTQVLHECL  
 WN2B_XENLA            --------------------------------------------------MHFAYILILLILTPRVDSSWWYIGALG--------------ARVICDNIPGLVNKQRQLCQKHPDIMQAIGEGAKEWIRECQHQFRHHRWNCSTLDRDHT-VFGRVMLRSSRETAFVYAISYAGVVYAITRACSQGELKSCNCDPKKRGRSKD------------------ERGEFDWGGCSDHIDFGIKFPKDFVDAKEKRL--KDARALMNLHNNRCGRMAVKRFMNLECKCHGVSGSCTLRTCWRAMSDFRKTGDFLRRRYNGAIQVTMNQDGSGFAVANQ----------NFRKATKKDLVYFENSPDYCVMDKTAGSLGTAGRVCDKVSRGTDGCEVMCCGRGYDTTRVTRITKCECKFH--WCCAVRCKECEETVDVHTCKAPKRAEWLDQT  
 Q98SN7                ----------------MLSPNRLAASPGIAVAPGRAECGAFPRTAGAAPRICLPFVLILLALTPRADSSWWYIGALG--------------ARVICDNIPGLVNKQRQLCQRYPDIMQSVGEGAKEWIRECQYQFRHHRWNCSTLDRDHT-VFGRVMLRSSREAAFVYAISSAGVVYAITRACSQGELKACGCDPLKRGRAKD------------------ERGEFDWGGCSDNINYGIRFAKAFVDAKEKKV--KDARALMNLHNNRCGRMAVKRFLKLECKCHGVSGSCTLRTCWLAMSDFRKTGDYLQKKYNGAIQVIMNQDGTGFTVANK----------NFRKPTKTDLVYFENSPDYCVMDKSAGSLGTAGRVCNKVSRGTDGCEVMCCGRGYDTTRVTRVTKCECKFH--WCCAVRCKECEDTVDVHTCKAPKRAEWLDQT  
 WN3A_MOUSE            -----------------------------------------------MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSL-------STQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGE---------------------GWKWGGCSEDIEFGGMVSREFADARENRP---DARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVET----LRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFH--WCCYVSCQECTRVYDVHTCK  
 Q9CZW3                -------------------------------------------MNVPLGGIWLWLPLLLTWLTPEVSSSWWYMRATG------------GSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHS-LFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGSAKD------------------SKGTFDWGGCSDNIDYGIKFARAFVDAKERKG--KDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANK----------RFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFH--WCCAVRCQDCLEALDVHTCKAPKSADWATPT  
 WNT2_MOUSE            -------------------------------------------MNVPLGGIWLWLPLLLTWLTPEVSSSWWYMRATG------------GSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHS-LFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGSAKD------------------SKGTFDWGGCSDNIDYGIKFARAFVDAKERKG--KDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGEYLWRKYNGAIQVVMNQDGTGFTVANK----------RFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFH--WCCAVRCQDCLEALDVHTCKAPKSADWATPT  
 Q8UW39                -------------------------------------------MNFVPSGICFYVSVALCWLTAEVDASWWYMGTLG--------------SQVMCDNIPGLVNKQRQLCRQHPKVMQAIGSGIKDWISECQHQFRNHRWNCNTTARDHN-LFGRLLLRSSREVAFIYALSSAGVVYALARACSQGDLDSCSCDPAKKGSSRD------------------AKGSFSWGGCSDHVDHAMRFSQAFVDAKERKE--RDARALMNLHNNRAGRKAVKRFMTLECKCHGVSGSCSVRTCWSAMADFRRTGDHLRKKYNGAVQVAVNQYGTGFTTAHA----------HFKQPGKNDLVYLEDSPDYCVRDQDSGSLGTGGRLCNRTSPGTDGCEVMCCGRGYDTSRVGRTTKCECKFH--WCCAVLCRDCHQQVDVHTCKGLT  
 WNT1_XENLA            ------------------------------------MRILTFLLG-LKTLWVLAFSSLSNTIAVNNSGKWWGIVNVASAGNVLPGSDARPVPLVLDPSLQLLSR-QKRLIRQNPGILQSITRGLHSAIRECKWHFRNRRWNCPTGTGNQ--VFGKIINRGCRETAFVFAITSAGVTHSVARSCSEGSIESCSCDYRRRGPGGP---------------------DWHWGGCSDNIEFGRFIGREFVDSSERG---RDLKYLVNLHNNQAGRLTVLTEMRQECKCHGMSGSCSLRTCWMRLPPFRSVGDALKDRFDGASKVTYSNNGSNRWGSRSDPPHLEPENPTHALPSSQDLVYFEKSPNFCSPSEKNGTPGTTGRICNSTSLGLDGCELLCCGRGYRSLAEKVTERCHCTFN--WCCHVTCLNCTSSQIVHECL  
 WNT4_HUMAN            ---------------------------------------------MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSI--------SEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCS--TLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQ---------------------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEP------RRVGSSRALVPRNAQFKPHTDE--DLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFH--WCCFVKCRQCQRLVELHTCR  
 WN3A_HUMAN            -----------------------------------------------MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSL-------GSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLA-IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGK---------------------GWKWGGCSEDIEFGGMVSREFADARENRP---DARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVET----LRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFH--WCCYVSCQECTRVYDVHTCK  
 WN2B_HUMAN            ----------MLRPGGAEEAAQLPLRRASAPVPVPSPAAPDGSRASARLGLACLLLLLLLTLPARVDTSWWYIGALG--------------ARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHT-VFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHD------------------QRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRL--KDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQ----------GYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFH--WCCAVRCKECRNTVDVHTCKAPKKAEWLDQT  
 WNT1_BRARE            ------------------------------------MRVLALLLA-VKAACVLLVSSLTGTGAVNNSGRWWGIVNVASSGNLL--TNSKNVQLVLDPSLALLSRRQRKLIRQNPGILHAIAAGLHTAIKECKWQFRNRRWNCPTTHSPN--VFGKIVNRGCRETAFVFAITSAGVTHAVARSCSEGAIESCTCDYRRRGPGGP---------------------DWHWGGCSDNVEFGRMFGREFVDSSERG---RDLRYLTNLHNNEAGRMTVASEMQQECKCHGMSGSCTVRTCWMRLPSFRLVGDYLKDRFDGASRVVYANKGSNRASHRADPRHLEPENPAHKLPSSRDLVYFEKSPNFCSYNGKTGTHGTSGRTCNSSSPALDGCELLCCGRGYKTRMEQVTERCHCTFH--WCCHVSCLNCTSTQTVHQCL